BioNanoInteractions. Image by Dr Iseult Lynch.
School of Chemistry & Chemical Biology - Research Publications 2006/07
Below is the list of research publications for the School of Chemistry & Chemical Biology in the academic year 2006/07
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| Professor Michael James McGlinchey | |
| McGlinchey, M. J., Ortin, Y., Seward, C. M. (2007) 'Chromium Compounds with CO or Isocyanides' In: D. M. P. Mingos & R. H. Crabtree (eds). Comprehensive Organometallic Chemistry III, Volume 5. Oxford, UK: Elsevier. | |
| Professor Robert O'Neill | |
| Killoran, S.J. and O'Neill, R.D. (2006) 'Electrosynthesis and permselective characterisation of mixed polymers of o-phenylenediamine for biosensor applications' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari. | |
| Kirwan S.M., Rocchitta G., Lowry J.P. and O'Neill R.D. (2006) 'Designing a polymer/enzyme composite biosensor suitable for clinical monitoring of glutamate in brain ECF' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari. | |
| O'Brien, K.B., Killoran, S.J., O'Neill, R.D. and Lowry, J.P. (2006) 'Development of a catalase based biosensor for the detection of endogenous hydrogen peroxide in brain extracellular fluid' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari. | |
| Rocchitta G., McMahon C.P., Serra P.A., Kirwan S.M., Bolger F.B., Lowry J.P. and O'Neill R.D. (2006) 'Significant enhancement of glutamate biosensor sensitivity, using a polycation-modified polymer/enzyme composite sensing layer' In: Monitoring Molecules in Neuroscience. Cagliari: University of Cagliari. | |
| Dr Vitaly Buckin | |
| Hickey, S., Lawrence, J., Hagan, S., Buckin, V. (2006) 'Analysis of the Phase Diagram and Microstructural Transitions in Phospholipid Microemulsion Systems using High-Resolution Ultrasonic Spectroscopy'. Langmuir, 22 :5575-5583. | |
| Professor Kenneth A Dawson | |
| Stubenrauch, C. et al. (2007) 'Gelled polymerizable microemulsions. 1. Phase behavior'. Langmuir, 23 :7730-7737. | |
| Linse, S. et al. (2007) 'Nucleation of protein fibrillation by nanoparticles'. PNAS, 104 :8691-8696. | |
| Lynch, I, et al. (2007) 'The nanoparticle–protein complex as a biological entity; a complex fluids and surface science challenge for the 21st century'. Advances in Colloid and Interface Science, 134-135 :167-174. | |
| Cedervall, T. et al. (2007) 'Detailed identification of plasma proteins adsorbed on copolymer nanoparticles'. Angewandte Chemie-International Edition in English, 46 :5754-5756. | |
| Cedervall, T. et al. (2007) 'Understanding the nanoparticle protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles'. PNAS, 104 :2050-2055. | |
| Lindman, S. et al. (2007) 'Systematic investigation of the thermodynamics of HSA adsorption to N-iso-propylacrylamide/N-tert-butylacrylamide copolymer nanoparticles. Effects of particle size and hydrophobicity'. Nano Letters, 7 :914-920. | |
| Lynch I, Dawson KA, Linse S. (2006) 'Surface-adsorbed proteins affect cellular signalling'. STKE, . | |
| Dr Paul Evans | |
| Kelleher, S., Muldoon, J., Müller-Bunz, H. and Evans, P. (2007) 'Studies concerning the double reduction of Diels–Alder derived bicylic sulfonamides'. Tetrahedron Letters, 48 . | |
| Banide E. V., Müller-Bunz H., Manning A. R., Evans P. and McGlinchey M. J. (2007) 'X-Ray Crystal Structure of an Unprecedented Alkene-Pentacarbonyldicobalt-Alkyne Complex: First Isolation of a Stable Magnus-Type Pauson-Khand Reaction Intermediate'. Angewandte Chemie International Edition, 46 . | |
| Evans, P. (2007) 'The Double Reduction of Cyclic Sulfonamides for the Synthesis of (4S-Phenylpyrrolidin-4R-yl)methanol and 2S-Methyl-4S-phenylpyrrolidine'. Journal of Organic Chemistry, 72 . | |
| Byrne, S. J., le Bon, B., Corr, S. A., Stefanko, M., O'Connor, C., Gun'ko, Y. K., Rakovich, Y. P., Donegan, J. F., Williams, Y., Volkov, Y., Evans, P. (2007) 'Synthesis, Characterisation, and Biological Studies of CdTe Quantum Dot-Naproxen Conjugates'. ChemMedChem, 2 . | |
| Professor Declan Gerard Gilheany | |
| Bergin, E., O'Connor, C. T., Robinson, S. B., McGarrigle, E. M., O'Mahony, C. P. and Gilheany, D. G. (2007) 'Synthesis of P-Stereogenic Phosphorus Compounds. Asymmetric Oxidation of Phosphines under Appel Conditions'. Journal of the American Chemistry Society . | |
| King, G., Bergin, E., Muller-Bunz, H., Gilheany, DG. (2007) '(R,R)-Ethylenebis[(2-methylphenyl)-phenylphosphine oxide] ('o-Tolyl DiPAMPO')'. Acta Crystallogr E, 63 :3278-409. | |
| Professor Patrick Guiry | |
| Hargaden, GC; McManus, HA; Cozzi, PG; Guiry, PJ; (2007) 'The application of bis(oxazoline) ligands in the catalytic enantioselective methallylation of aldehydes'. Organic & Biomolecular Chemistry, 5 (5):763-766. | |
| Coyne, AG; Guiry, PJ; (2007) 'Rhodium-catalysed asymmetric hydrosilylation of ketones using HETPHOX ligands'. Tetrahedron Letters, 48 (5):747-750. | |
| Professor Michael James McGlinchey | |
| Banide, E.V., Molloy, B.C., Ortin, Y., Muller-Bunz, H., McGlinchey, M.J. (2007) 'From allenes to tetracenes: A synthetic and structural study of silyl- and halo-allenes and their dimers'. Eur J Org Chem, :2611-2622. | |
| Nikitin, K., Muller-Bunz, H., Ortin, Y., McGlinchey, M.J. (2007) 'Joining the rings: the preparation of 2- and 3-indenyl-triptycenes, and curious related processes'. Org Biomol Chem, 5 :1952-1960. | |
| Banide, E.V., Muller-Bunz, H., Manning, A.R., Evans, P., McGlinchey, M.J. (2007) 'X-ray crystal structure of an alkene-pentacarbonyldicobalt-alkyne complex: Isolation of a stable Magnus-type Pauson-Khand reaction intermediate'. Angew Chem Int Edit, 46 :2907-2910. | |
| Dr Grace Morgan | |
| McKee, V., Nelson, J. and Morgan, G. G. (2006) 'Tris[2-(2-nitrobenzylideneamino)ethyl]amine'. Acta Cryst. E, 62 (9):3747-3749. | |
| Morgan, G. G., Murnaghan, K. D., Muller-Bunz, H., McKee, V. and Harding, C. J. (2006) 'Manganese(III) Spin Crossover Triggered by Geometric Tuning'. Angew. Chem. Int. Ed, 45 :7192-7195. | |
| Professor Paul Murphy | |
| Danieli, E., Lalot, J., Murphy, P.V. (2007) 'Selective protecting group manipulations on the 1-deoxynojirimycin scaffold'. Tetrahedron, 63 :6827-6834. | |
Loukou,C., Tosin, M., Müller-Bunz, H., Murphy, P.V. (2007) 'Synthesis of sugar-lactams from azides of glucuronic acid'. Carbohydrate Research, 342 :1953-1959.  |
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| Zaric, V., Doyle, D., Murphy, P.V., O’ Boyle, K.M. (2007) 'Inhibition of endothelial cell proliferation by N-?-D-mannopyranosyl-thiophene-2-carboxamides'. AntiCancer Research, 27 :1331-1336. | |
| O'Brien, C., Polakova, M., Pitt, N., Tosin, M., Murphy, P.V., (2007) 'Glycosidation-anomerisation reactions of 6,1-anhydroglucopyranuronic acid and anomerisation of beta-D-glucopyranosiduronic acids promoted by SnCl4'. Chemistry-A European Journal, 13 (3):902-909. | |
| Cronin, L., Tosin, M., Muller-Bunz, H., Murphy, P.V. (2007) 'The synthesis of cyclicimidates from amides of glucuronic acid and investigation of glycosidation reactions'. Carbohydrate Research, 342 (1):111-118. | |
| Paul V. Murphy* and Julie L. Dunne (2006) 'Syntheses of peptidomimetics based on pyranose and polyhydroxylated piperidine scaffolds'. Curr. Org. Synth . | |
| Professor Robert O'Neill | |
| O'Brien, K. B., K illoran, S. J., O'Neill, R. D., Lowry, J. P. (2007) 'Development and characterization in vitro of a catalase-based biosensor for hydrogen peroxide monitoring'. Biosensors & Bioelectronics, 22 (12):2994-3000. | |
| Serra, P. A., Rocchitta, G., Bazzu, G., Manca, A., Puggioni, G. M., Lowry, J. P., O'Neill, R. D. (2007) 'Design and construction of a low cost single-supply embedded telemetry system for amperometric biosensor applications'. Sensors and Actuators B-Chemical, 122 (1):118-126. | |
| McMahon, C. P., Rocchitta, G., Kirwan, S. M., Killoran, S. J., Serra, P. A., Lowry, J. P., O'Neill, R. D. (2007) 'Oxygen tolerance of an implantable polymer/enzyme composite glutamate biosensor displaying polycation-enhanced substrate sensitivity'. Biosensors & Bioelectronics, 22 (7):1466-1473. | |
| Kirwan, S. M., Rocchitta, G., McMahon, C. P., Craig, J. D., Killoran, S. J., O'Brien, K. B., Serra, P. A., Lowry, J. P., O'Neill, R. D. (2007) 'Modifications of poly(o-phenylenediamine) permselective layer on Pt-Ir for biosensor application in neurochemical monitoring'. Sensors, 7 (4):420-437. | |
| Dr Donal O'Shea | |
| Cottineau, B., O’Shea, D. F. (2007) '7-Azaindoles via carbolithiation of vinyl pyridines'. Tetrahedron, 63 :10354-10362. | |
| Gallagher, J.F., Le-Bas, M.-D. H., Coleman, C.M., O’Shea, D.F. (2007) '6-(4-Fluorophenyl) -8-phenyl-2,3-dihydro-4H-imidazo[5,1-b][1,3]thiazin-4-one: An Unusual [6-5] Fused Ring System'. Acta Crystallography, C63 :160-165. | |
| Cotter, J., Hogan, A.-M.L., O’Shea, D.F. (2007) 'Development and Application of a Direct Vinyl Lithiation of cis-Stilbene and a Directed Vinyl Lithiation of an Unsymmetrical cis-Stilbene'. Organic Letters, 9 :1493-1497. |
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| McKinley, N.F., O’Shea, D.F. (2006) 'Carbolithiation of Diphenylacetylene as a Stereoselective Route to (Z)-Tamoxifen and Related Tetra-substituted Olefin Analogues'. Journal of Organic Chemistry . | |
| Dr Wilhelm Risse | |
| K. Curran, W. Risse, L. Boggioni, I. Tritto, (2007) 'Olefin Addition Polymerisation of Cyclobutene-Type Monomers with Early and Late Transition Metal Compounds'. Polymer Preprints, 48 (1). | |
| Professor Howard Sidebottom | |
| Sidebottom, H., Solignac, G., Mellouki, A., Le Bras, G. and Yujing, Mu. (2007) 'The gas phase tropospheric removal of fluoroaldehydes (CxF2x+1CHO,x=3,4,6)'. Physical Chemistry Chemical Physics, 9 :4200-4210. |
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| Dr James Anthony Sullivan | |
| Sullivan, J. A., and Keane, O. (2007) 'A combination of NOx trapping materials and Urea-SCR catalysts for use in the removal of NOx from mobile diesel engines'. Applied Catalysis B: Environmental. | |
| Sullivan J.A., Keane, O. and Cassidy, A. (2007) 'Beneficial and problematic interactions between NOx trapping materials and carbonaceous particulate matter'. Applied Catalysis B: Environmental, 75 :102-106. | |
| Dr Matthias Tacke | |
| Pampillón, C., Claffey, J., Hogan, M., Tacke, M. (2007) 'Morpholino-Functionalised and Heteroaryl-Substituted Titanocene Anticancer Drugs: Synthesis and Cytotoxicity Studies'. Zeitschrift fuer Anorganische und Allgemeine Chemie, 633 (10):1695-1700. | |
| Müller-Bunz, H., Dix, I., Lou, Y., Pampillón, C., Strohfeldt, K., Sweeney, N. J., Tacke, M. (2007) 'A series of novel 6-aryl fulvenes: Impact of substitution on the phenyl ring, characterised by X-Ray crystallography'. Zeitschrift Fur Krystallographie, 222 (7):376-882. | |
| Hogan, M., Claffey, J. Pampillón, C., Watson, R. W. G., Tacke, M. (2007) 'Synthesis and Cytotoxicity Studies of New Dimethylamino-Functionalised and Azole-Substituted Titanocene Anti-Cancer Drugs'. Organometallics, 26 (10):2501-2506. | |
| Pampillón, C., Claffey, J., Hogan, M., Strohfeldt, K., Tacke, M. (2007) 'Synthesis and Cytotoxicity Studies of New Dimethylamino-Functionalised and Indolyl-Substituted Titanocene Anti-Cancer Drugs'. Transition Metal Chemistry, 32 (4):434-441. | |
| Pampillón, C. Sweeney, N. J., Strohfeldt, K., Tacke, M. (2007) 'Synthesis and Cytotoxicity Studies of New Dimethylamino-Functionalised and Heteroaryl-Substituted Titanocene Anti-Cancer Drugs'. Journal of Organometallic Chemistry, 692 (11):2153-2159. | |
| Beckhove, P., Hanauske, A.-R., Oberschmidt, O., Pampillón, C., Schirrmacher, V., Sweeney, N. J., Strohfeldt, K., Tacke, M. (2007) 'Antitumor Activity of Titanocene Y in Freshly Explanted Human Breast Tumors and in Xenografted MCF-7 Tumors in Mice'. Anti-Cancer Drugs, 18 (3):311-315. | |
| Oberschmidt, O., Hanauske, A.-R., Pampillón, C., Strohfeldt, K., Sweeney,N. J., Tacke, M. (2007) 'Activity of Titanocene Y against Tumor Colony Forming Units'. Anti-Cancer Drugs, 18 (3):317-321. | |
| Sweeney, N.J., Claffey, J., Muller-Bunz, H., Pampillon, C., Strohfeldt, K., Tacke, M. (2007) 'The synthesis and cytotoxic evaluation of a series of benzodioxole substituted titanocenes'. Applied Organometallic Chemistry, 21 (2):57-65. | |
| Sweeney, NJ; Claffey, J; Muller-Bunz, H; Pampillon, C; Strohfeldt, K; Tacke, M; (2007) 'The synthesis and cytotoxic evaluation of a series of benzodioxole substituted titanocenes'. Appl Organomet Chem, 21 :57-65. | |
| Dr Edward Timoshenko | |
| Bellesia, G., Fedorov, M.V., Timoshenko, E.G. (2007) 'Molecular dynamics study of structural properties of beta-sheet assemblies formed by synthetic de novo oligopeptides'. Physica A-Statistical Mechanics and it's Applications, 373 (NA):455-476. | |
| Dr Xiangming Zhu | |
| Zhu, X., Jin, Y., Wickham, J. (2007) 'Efficient Synthesis of Methylene exo-Glycal: Another Use of Glycosylthiomethyl Chlorides'. Journal of Organic Chemistry, 72 :2670-2673. | |
| Zhu, X., Kawatkar, S., Rao, Y., Boons, G. J. (2006) 'A Practical Approach for the Stereoselective Introduction of ?-L-Arabinofuranosides'. Journal of the American Chemistry Society, 128 :11948-11957. | |
| Dr Paul Evans | |
| Bickley, J. F., Evans, P., Meek, A., Morgan, B. S. Roberts, S. M. (2006) 'Novel Preparation of (-)-4-Hydroxycyclohex-2-enone: Reaction of 4-Hydroxycyclohex-2-enone and 4-hydroxycyclopent-2-enone with some Thiols' Tetrahedron Asymmetry . | |
| Mr Alexander Gorelov | |
| Kavanagh, C.A., Gorelova, T.A., Selezneva, II., Rochev, Y.A., Dawson, K.A., Gallagher, W.M., Gorelov, A.V., Keenan, A.K. (2006) 'Poly(N-isopropylacrylamide) copolymer films as vehicles for the sustained delivery of proteins to vascular endothelial cells' J Biomed Mater Res A, 72 (1):25-35. | |
| Professor Patrick Guiry | |
| Quinn, S.T., Guiry, P.J., Schwabb, T., Keenan, A.K.; McBean, G.J. (2006) 'Blockade of noradrenaline transport abolishes 4-methylthioamphetamine-induced contraction of the rat aorta in vitro' J. Autonomic & Autacoid Pharm . | |
| Dr Iseult Lynch | |
| Lynch, I., Dawson, K.A., Linse, S. (2006) 'Detecting cryptic epitopes created by nanoparticles' Science STKE . | |
| Professor Howard Sidebottom | |
| Nolan, L., Guihur, A-L., Manning, M., Sidebottom, H. (2006) 'Atmospheric oxidation of the chlorinated solvents, 1,1,1-trichloroethane, trichloroethene and tetrachloroethene' NATO Science Series . | |
| Dr Matthias Tacke | |
| O’Connor, K., Gill, C., Tacke, M., Rehmann, F.-J. K., Strohfeldt, K., Sweeney, N., Fitzpatrick, J. M., Watson, R. W. G. (2006) 'Novel Titanocene Anti-Cancer Drugs and their Effect on Apoptosis and the Apoptotic Pathway in Prostate Cancer Cells' Apoptosis . | |
| Professor Paul Murphy | |
| Anquetin, G., Rawe, S.L., Murphy, P.V. (2007) Synthesis and anticancer activity of new migrastatin analogs 234th ACS National Meeting. | |
| Dr Donal O'Shea | |
| O'Shea, D.F. (2007) Directed Stilbene Lithiation 8th International Symposium on Carbanion Chemistry, Madison, WI, USA. | |
| O'Shea, D.F. (2007) New Light Activated Anti-cancer Agents Central European Society for Anticancer Drug Research Meeting, Frankfurt, Germany. | |
| Dr James Anthony Sullivan | |
| Flanagan,K. and Sullivan, J.A. (2007) Preparation, Characterisation and Assessment of the Catalytic Activity of an Aqueous Dispersion of Palladium Nanoparticles and a MWCNT Supported Palladium Nanoparticle Composite Europacat VIII Turku, Finland, | |
| Sullivan, J.A., Dulgheru, P. and Keane, O. (2007) The Influence of Transient H2 and 13CH3OH pulses on the soot combustion activity of Pt catalysts containing NOx trapping materials Europacat VIII Turku, Finland. | |
