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'A clock glass with Iodine crystals in Dichloromethane'. Image by Ms Susan Kelleher.
School of Chemistry & Chemical Biology - Research Publications 2007/08
Below is the list of research publications for the School of Chemistry & Chemical Biology in the academic year 2007/08
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| Professor Patrick Guiry | |
| McManus, H. A.; Cusack, D.; Guiry, P. J. (2008) 'P/Oxazoline Ligands' In: Armin Börner (eds). Phosphorus Ligands In Asymmetric Catalysis - Synthesis and Applications. Weinheim: Wiley-VCH. | |
| Coyne, A. G.; Guiry, P. J. (2008) 'The Development and Application of Rhodium-Catalysed Hydroboration of Alkenes' In: P.G. Andersson, I. Munslow (eds). Modern Reduction Methods. Weinheim: Wiley-VCH. | |
| Dr Wilhelm Risse | |
| Breen, Darragh; Curran, Katherine; Risse, Wilhelm (2007) 'Stereochemistry of polymers formed by metathesis polymerization of bicyclic and polycyclic olefins' In: Baugh, Lisa S.; Canich, Jo Ann M (eds). Stereoselective Polymerization with Single-Site Catalysts. Boca Raton, Fla: CRC Press LLC. | |
| Dr Xiangming Zhu | |
Richard R. Schmidt, Xiangming Zhu (2008) 'Glycosyl Trichloroacetimidates' In: Bertram O. Fraser-Reid, Kuniaki Tatsuta, Joachim Thiem (eds). Glycoscience - Chemistry and Chemical Biology. Berlin Heidelberg: Springer-Verlag. |
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| Xiangming Zhu, Richard R. Schmidt (2008) 'Glycoside Synthesis from 1-Oxygen-Substituted Glycosyl Imidates' In: Alexei V. Demchenko (eds). Handbook of Chemical Glycosylation. Weinheim: Wiley-VCH. | |
| Dr Michael Casey | |
| Grealis, J. P., Muller-Bunz, H., Ortin, Y., Condell, M., Casey, M., McGlinchey, M. J., (2008) 'Birch reduction of hexaphenyl- and pentaphenylbenzene and an X-ray crystallography and NMR spectroscopy study of cis- and epi-1,2,3,4,5,6-hexaphenylcyclohexane and of 2,3,5,6-tetraphenyl-1,1 '-bicyclohexylidene: Cannizzaro's conundrum revisited'. Chemistry-A European Journal, 14 (5):1552-1560. | |
| Banide, E. V., Grealis, J. P., Mueller-Bunz, H., Ortin, Y., Casey, M., Mendicute-Fierro, C., Lagunas, M. C., McGlinchey, M. J., (2008) 'Chromium, iron, ruthenium and gold complexes of 3,3-(biphenyl-2,2 '-diyl)-1-diphenylphosphino-1-phenylallene: A versatile ligand'. Journal of Organometallic Chemistry, 693 (10):1759-1770. | |
| Grealis, J. P., Muller-Bunz, H., Casey, M., McGlinchey, M. J., (2008) 'Cannizzaro's (C7H6)n conundrum resolved: [1.1.1]orthocyclophane was first made 150 years ago'. Tetrahedron Letters, 49 (9):1527-1530. | |
| Professor Kenneth A Dawson | |
| Lynch, I., Dawson, K. A., (2008) 'Protein-nanoparticle interactions'. Nano Today, 3 (1-2):40-47. | |
| Dr Paul Evans | |
| M. J. Stefanko, Y. K. Gun¿ko and P. Evans (2008) 'Synthesis of Functionalised Polyethylene Glycol Derivatives of Naproxen for Biomedical Applications'. Tetrahedron, 64 (44):10132-10139. | |
| A. O¿Byrne and P. Evans, (2008) 'Rapid synthesis of the tetrahydroquinoline alkaloids; angustureine, cuspareine and galipinine'. Tetrahedron, 64 (35):8067-8072. | |
| B. Bradshaw, P. Evans, J. Fletcher, A. T. L. Lee, P. G. Mwashimba, D. Oehlrich, E. J. Thomas, R. H. Davies, B. C. P. Allen, K. J. Broadley, A. Hamrouni and C. Escargueil (2008) 'Synthesis of 5-Hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-ones; Selective Antagonists of Muscarinic (M3) Receptors'. Organic and Biomolecular Chemistry, 6 (12):2138-2157. | |
| P. Evans, A. T. L. Lee and E. J. Thomas (2008) 'Synthesis of a 6-Aryloxymethyl-5-hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-one: a Muscarinic (M3) Antagonist'. Organic and Biomolecular Chemistry, 6 (12):2158-2167. | |
| Professor Declan Gerard Gilheany | |
| Lee J. Higham, Jimmy Muldoon, P. Gabriel Kelly, David M. Corr, Helge Mueller-Bunz and Declan G. Gilheany (2007) 'A Re-Evaluation of the Electrophilic Substitution Reactions of the Ramirez Ylide'. Journal of Organic Chemistry, 72 :8780-8785. | |
| Professor Patrick Guiry | |
| Guiry PJ, Singh S, Duffy CD, Shah ST, (2008) 'ZrCl4 as an efficient catalyst for a novel one-pot protection/deprotection synthetic methodology'. Journal of Organic Chemistry, 73 (16):6429-6432. | |
| Guiry PJ, Shah ST, (2008) 'The chemoselective and efficient deprotection of silyl ethers using trimethylsilyl bromide'. Org Biomol Chem, 12 (NA):2168-2172. | |
| Guiry PJ, Hargaden GC, O'Sullivan TP, (2008) 'Synthesis of non-symmetric bis(oxazoline)-containing ligands and their application in the catalytic enantioselective Nozaki-Hiyama-Kishi allylation of benzaldehyde'. Org Biomol Chem, 3:562-566. | |
| Hargaden GC, Guiry PJ (2008) 'The development of the asymmetric Nozaki-Hiyama-Kishi reaction (vol 349, pg 2407, 2007)'. Advanced Synthesis & Catalysis, 350 (1):9-9. | |
| McBean GJ, Montgomery T, Buon C, Eibauer S, Guiry PJ, Keenan AK, (2007) 'Comparative potencies of 3,4-methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [3H]noradrenaline and [3H]5-HT transport in mammalian cell lines'. Brit. J. Pharm, 7 (NA):1121-1130. | |
| Guiry PJ, O'Sullivan TP, Vallin KS, Shah ST, Fakhry J, Maderna P, Scannell M, Sampaio AL, Perretti M, Godson C, (2007) 'Aromatic lipoxin A4 and lipoxin B4 analogues display potent biological activities'. Journal of medicinal chemistry, 24:5894-5902. | |
| Hargaden GC, Muller-Bunz H, Guiry PJ (2007) 'New proline-oxazoline ligands and their application in the asymmetric Nozaki-Hiyama-Kishi reaction'. European Journal of Organic Chemistry, (25):4235-4243. | |
| Professor Gil Lee | |
| W.S. Chang, H. Shang, R.M. Perera, S.M. Lok, D. Sedlak, R.J. Kuhn, and G.U Lee (2008) 'Rapid Detection of Dengue Virus in Serum using Magnetic Separation and Fluorescence Detection'. Analyst, 133 (2):233-240. | |
| V.A. Gorti, H. Shang, S.T. Wereley, and G.U Lee (2008) 'Immunoassays in Nanoliter Volume Reactors using Fluorescent Particle Diffusometry'. Langmuir, 24 (6):2947-2952. | |
| A. Kumar, V.M. Gorti, H. Shang, G.U Lee, N.K. Yip, and S.T. Wereley (2008) 'Optical Diffusometry Techniques and Applications in Biological Agent Detection'. Journal of Fluids Engineering-Transactions of the ASME, 130, 11, 111401, 130 (11):111-401. | |
| Professor Michael James McGlinchey | |
| Grealis, J. P., Muller-Bunz, H., Ortin, Y., Condell, M., Casey, M., McGlinchey, M. J., (2008) 'Birch reduction of hexaphenyl- and pentaphenylbenzene and an X-ray crystallography and NMR spectroscopy study of cis- and epi-1,2,3,4,5,6-hexaphenylcyclohexane and of 2,3,5,6-tetraphenyl-1,1 '-bicyclohexylidene: Cannizzaro's conundrum revisited'. Chemistry-A European Journal, 14 (5):1552-1560. | |
| Nikitin, K., Mueller-Bunz, H., Ortin, Y., Risse, W., McGlinchey, M. J., (2008) 'Twin triptycyl spinning tops: A simple case of molecular gearing with dynamic C2 symmetry'. European Journal of Organic Chemistry, (18):3079-3084. | |
| Ogini, F. O., Ortin, Y., Mahmoudkhani, A. H., Cozzolino, A. F., McGlinchey, M. J., Vargas-Baca, I., (2008) 'An investigation of the formation of 1,3,5-heterosubstituted benzene rings by cyclo-condensation of acetyl-substituted organometallic complexes'. Journal of Organometallic Chemistry, 693 (11):1957-1967. | |
| Banide, E. V., Grealis, J. P., Mueller-Bunz, H., Ortin, Y., Casey, M., Mendicute-Fierro, C., Lagunas, M. C., McGlinchey, M. J., (2008) 'Chromium, iron, ruthenium and gold complexes of 3,3-(biphenyl-2,2 '-diyl)-1-diphenylphosphino-1-phenylallene: A versatile ligand'. Journal of Organometallic Chemistry, 693 (10):1759-1770. | |
| Payen, O., Top, S., Vessieres, A., Brule, E., Plamont, M. A., McGlinchey, M. J., Muller-Bunz, H., Jaouen, G., (2008) 'Synthesis and structure-activity relationships of the first ferrocenyl-aryl-hydantoin derivatives of the nonsteroidal antiandrogen nilutamide'. Journal of Medicinal Chemistry, 51 (6):1791-1799. | |
| Grealis, J. P., Muller-Bunz, H., Casey, M., McGlinchey, M. J., (2008) 'Cannizzaro's (C7H6)n conundrum resolved: [1.1.1]orthocyclophane was first made 150 years ago'. Tetrahedron Letters, 49 (9):1527-1530. | |
| Professor Paul Murphy | |
| Anquetin, G., Horgan, G., Rawe, S., Murray, D., Madden, A., MacMathuna, P., Doran, P., Murphy, P. V., (2008) 'Synthesis of novel macrolactam and macroketone analogues of migrastatin from D-glucal and comparison with macrolactone and acyclic analogues: A dorrigocin A congener is a potent inhibitor of gastric cancer cell migration'. European Journal of Organic Chemistry, (11):1953-1958. | |
| Anquetin, G., Rawe, S. L., McMahon, K., Murphy, E. P., Murphy, P. V., (2008) 'Synthesis of novel migrastatin and Dorrigocin A analogues from D-glucal'. Chemistry-A European Journal, 14 (5):1592-1600. | |
| Chagnault, V., Lalot, J., Murphy, P. V., (2008) 'Synthesis of somatostatin mimetics based on 1-deoxynojirimycin'. Chemmedchem, 3 (7):1071-1076. | |
| Zhao, Y. X., Zhou, Y., O'Boyle, K. M., Murphy, P. V., (2008) 'Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis'. Bioorganic and Medicinal Chemistry, 16 (12):6333-6337. | |
| Murphy PV, Zhao Y, Zhou Y, O'Boyle KM, (2008) 'Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis'. Bioorganic & medicinal chemistry, 12 (NA):6333-6337. | |
| Zhou, Y., Zhao, Y., O'Boyle, K. M., Murphy, P. V., (2008) 'Hybrid angiogenesis inhibitors: Synthesis and biological evaluation of bifunctional compounds based on 1-deoxynojirimycin and aryl-1,2,3-triazoles'. Bioorganic & Medicinal Chemistry Letters, 18 (3):954-958. | |
| Loukou, C., Tosin, M., Miiller-Bunz, H., Murphy, P. V., (2008) 'Synthesis of sugar-lactams from azides of glucuronic acid (vol 342, pg 1953, 2007)'. Carbohydrate Research, 343 (2):412-413. | |
Murphy, P.V. (2007) 'Peptidomimetics, glycomimetics and scaffolds from carbohydrate building blocks'. European Journal of Organic Chemistry, :4177-4187. |
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| Professor Robert O'Neill | |
| Killoran SJ, O'Neill RD, (2007) 'Characterization of permselective coatings electrosynthesized on Pt-Ir from the three phenylenediamine isomers for biosensor applications' Electrochimica Acta, 7303-7312 | |
| Rothwell SA, Killoran SJ, Neville EM, et al.(2008) 'Poly(o-phenylenediamine) electrosynthesized in the absence of added background electrolyte provides a new permselectivity benchmark for biosensor applications' Electrochemistry Communications, 1078-1081 | |
| Migheli R, Puggioni G, Dedola S, et al. (2008) 'Novel integrated microdialysis-amperometric system for in vitro detection of dopamine secreted from PC12 cells: Design, construction, and validation' Analytical Biochemistry, 323-330 | |
| O'Neill RD, Lowry JP, Rocchitta G, et al. (2008) 'Designing sensitive and selective polymer/enzyme composite biosensors for brain monitoring in vivo' Trac-Trends in Analytical Chemistry, 78-88 | |
| Rocchitta G, Migheli R, Dedola S, et al. (2007) 'Development of a distributed, fully automated, bidirectional telemetry system for amperometric microsensor and biosensor applications' Sensors and Actuators B-Chemical, 700-709 | |
| Killoran SJ, Rai DK, O'Neill RD, (2007) 'Comparison of phenylenediamine isomers for the synthesis of permselective biosensor polymers for neurochemical analysis' Journal of Neurochemistry, 196-197 | |
| Kinsella ME, Lowry JP, O'Neill RD, (2007) 'Biosensor for the neurotransmitter L-glutamic acid: Development and characterisation' Journal of Neurochemistry, 197-197 | |
| Rothwell SA, O'Neill RD (2007) 'PT fibre as a novel electrode material in PPD-based biosensor design for neurotransmitter glutamate' Journal of Neurochemistry, 198-198 | |
| O'Brien KB, Killoran SJ, O'Neill RD, et al. (2007) 'Development and characterization in vitro of a catalase-based biosensor for hydrogen peroxide monitoring' Biosensors & Bioelectronics, 2994-30000 | |
| Kirwan SM, Rocchitta G, McMahon CP, et al. (2007) 'Modifications of poly(o-phenylenediamine) permselective layer on Pt-Ir for biosensor application in neurochemical monitoring' Sensors, 420-437 | |
| Professor Donal O'Shea | |
| Hogan AML, Tricotet T, Meek A, et al. (2008) 'Applications of enantioselective carbolithiation of ortho-substituted beta-methylstyrenes'. Journal of Organic Chemistry, 73 (15):6041-6044. | |
| Hogan AML, O'Shea DF (2008) 'Asymmetric cascade reaction sequences via chiral lithiated intermediates'. Journal of Organic Chemistry, 73 (7):2503-2509. | |
| Killoran J, McDonnell SO, Gallagher JF, et al. (2008) 'A substituted BF2-chelated tetraarylazadipyrromethene as an intrinsic dual chemosensor in the 650-850 nm spectral range'. New Journal of Chemistry, 32 (3):483-489. | |
| Hogan AML, O'Shea DF (2007) 'Carbolithiation of o-Amino-(E)-Stilbenes: Diastereoselective electrophile substitution with applications to quinoline synthesis'. Journal of Organic Chemistry, 72 (25):9557-9571. | |
| O'Connor AE, Byrne AT, Mcgee MM, et al. (2007) 'A potent nonporphyrin class of photodynamic therapeutic agent: Preclinical and mechanistic studies'. Molecular Cancer Therapeutics, 6 (12):3378S-3378S. | |
| Cottineau B, O'Shea DF (2007) '7-Azaindoles via carbolithiation of vinyl pyridines'. Tetrahedron, 63 (41):10354-10362. | |
| Dr Wilhelm Risse | |
| Nikitin, K., Mueller-Bunz, H., Ortin, Y., Risse, W., McGlinchey, M. J., (2008) 'Twin triptycyl spinning tops: A simple case of molecular gearing with dynamic C2 symmetry'. European Journal of Organic Chemistry, (18):3079-3084. | |
| Curran, K., Risse, W., Boggioni, L., Tritto, I., (2008) 'Addition polymers of strained cyclic olefins - Transition metal catalysed polymerisations of the cyclobutene derivative bicyclo[3.2.0]hept-6-ene'. Macromolecular Chemistry and Physics, 209 (7):707-714. | |
| Dr James Anthony Sullivan | |
| Flanagan, K.A., Sullivan, J.A. and Mulleur-Bunz, H. (2007) 'The Preparation and Characterization of 4-Dimethylaminopyridine (DMAP) Stabilized Palladium nanoparticles'. Langmuir, 23 (25):12508-12520. | |
| Dr Matthias Tacke | |
| Pampillon, C., Claffey, J., Strohfeldt, K., Tacke, M., (2008) 'Synthesis and cytotoxicity studies of new dimethylamino-functionalised and aryl-substituted titanocene anti-cancer agents'. European Journal of Medicinal Chemistry, 43 (1):122-128. | |
| Strohfeldt, K., Tacke, M., (2008) 'Bioorganometallic fulvene-derived titanocene anti-cancer drugs'. Chemical Society Reviews, 37 (6):1174-1187. | |
| Hogan, M., Claffey, J., Pampillon, C., Tacke, M., (2008) 'Synthesis and cytotoxicity studies of new morpholino-functionalised and N-heteroaryl-substituted titanocene anticancer drugs'. Medicinal Chemistry, 4 (2):91-99. | |
| Pampillon, C., Claffey, J., Hogan, M., Tacke, M., (2008) 'Novel achiral titanocene anti-cancer drugs synthesised from bis-N,N-dimethylamino fulvene and lithiated heterocyclic compounds'. Biometals, 21 (2):197-204. | |
| Weber, H., Claffey, J., Hogan, M., Pampillon, C., Tacke, M., (2008) 'Analyses of Titanocenes in the spheroid-based cellular angiogenesis assay'. Toxicology in Vitro, 22 (2):531-534. | |
| Dowling, C. M., Claffey, J., Cuffe, S., Fichtner, I., Pampillon, C., Sweeney, N. J., Strohfeldt, K., Watson, R. W. G., Tacke, M., (2008) 'Antitumor activity of Titanocene Y in xenografted PC3 tumors in mice'. Letters in Drug Design & Discovery, 5 (2):141-144. | |
| M. Tacke (2008) 'The Interaction of Titanocene Y with Double-Stranded DNA: A Computational Study'. Letters in Drug Design & Discovery, 5 :332-335. | |
| J. Claffey, B. Gleeson, M. Hogan, H. Müller-Bunz, D. Wallis, M. Tacke (2008) 'Fluorinated Derivatives of Titanocene Y: Synthesis and Cytotoxicity Studies'. European Journal of Inorganic Chemistry, :4074-4082. | |
| J. Claffey, M. Hogan, H. Müller-Bunz, C. Pampillón, M. Tacke (2008) 'Oxali-Titanocene Y: A Potent Anticancer Drug'. Chemmedchem, 3 :729-731. | |
| Claffey, J., Hogan, M., Muller-Bunz, H., Pampillon, C., Tacke, M., (2008) 'Synthesis and cytotoxicity studies of methoxy benzyl substituted titanocenes'. Journal of Organometallic Chemistry, 693 (3):526-536. | |
| M. Hogan, J. Claffey, E. Fitzpatrick, T. Hickey, C. Pampillon, M. Tacke (2008) 'Synthesis and Cytotoxicity Studies of Titanocene C Analogues'. Metal-Based Drugs . | |
| T. Hickey, J. Claffey, E. Fitzpatrick, M. Hogan, C. Pampillón, M. Tacke (2007) 'Dimethylamino-Functionalised and N-Heteroaryl-Substituted Titanocene Anticancer Drugs: Synthesis and Cytotoxicity Studies'. Investigational New Drugs, 25 (5):425-433. | |
| Strohfeldt, K., Müller-Bunz, H., Pampillón, C., Tacke, M. (2007) 'Proliferative and Antiproliferative Effects in Substituted Titanocene Anticancer Drugs'. Transition Metal Chemistry, 32 (7):971-980. | |
| Dr Edward Timoshenko | |
| Bellesia, G., Fedorov, M. V., Timoshenko, E. G., (2008) 'Structural transitions in model beta-sheet tapes'. Journal of Chemical Physics, 128 (19). | |
| Elli, S., Raffaini, G., Ganazzoji, F., Timoshenko, E. G., Kuznetsov, Y. A., (2008) 'Surface adsorption of comb polymers by Monte Carlo simulations'. Polymer, 49 (6):1716-1724. | |
| Professor Earle Waghorne | |
| Feakins, D., Bates, F. M., Waghorne, W. E., (2008) 'Quasi-thermodynamics of viscous flow of electrolyte solutions in aqueous, non-aqueous and mixed aqueous solvents'. Journal of Solution Chemistry, 37 (6):727-747. | |
| Dr Xiangming Zhu | |
| Dere, R. T., Wang, Y. X., Zhu, X. M., (2008) 'A direct and stereospecific approach to the synthesis of alpha-glycosyl thiols'. Organic and Biomolecular Chemistry, 6 (12):2061-2063. | |
| Wang, X. X., Li, Z. F., Zhu, X. M., Mao, H., Zou, X. F., Kong, L. C., Li, X. S., (2008) 'Features and applications of reactions of alpha,beta-unsaturated N-acylbenzotriazoles with amino compounds'. Tetrahedron, 64 (27):6510-6521. | |
| Professor Declan Gerard Gilheany | |
| Gilheany, DG (2008) 'Control and Exploitation of Phosphine Oxidation: The Taming of a Chemical Enfant Terrible' Irish Chemical News . | |
| Dr James Anthony Sullivan | |
| Sullivan and Sherry (2008) Acidic and Basic Heterogeneous Catalysts for Biodiesel Production 5th International conference on Environmental Catalysis. | |
| Sullivan and Dulgheru (2008) The effect of changing the NOx storage component in an NSR catalyst on soot combustion 10th International Symposium on Heterogeneous Catalysis. | |
| Sullivan, J.A., Flanagan, K. and Hain, H. (2007) Selective H-D exchange catalysed by aqueous phase Pd nanoparticles COST D36 Workshop, Molecular structure-performance relationships at the surface of functional materials Helsinki Finland. | |
| Dr Matthias Tacke | |
| Dowling, C. M., Cuffe, S., Gill, C., Tacke, M., Fitzpatrick, J. M., Watson, R. W. G., (2008) European Urology Supplements Effects of docetaxel and novel titanocene analogues on cell death in prostate cancer following downregulation of Id-1 and the IAPS, 276 - 276 | |
| Cuffe, S., Dowling, C., Gill, C., Tacke, M., Fitzpatrick, J. M., Carty, M. P., Watson, R. W. G., (2008) Ejc Supplements Novel titanocene analogues induce apoptosis in prostate cancer epithelial cells by initiating a DNA damage response, 29 - 29 | |