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'Stuck like glue.' Image by Dr Anika Mostaert.

'Stuck like glue.' Image by Dr Anika Mostaert.

UCD Conway Institute - Research Publications 2008/09

Below is the list of research publications for the UCD Conway Institute in the academic year 2008/09




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Books
Professor Ulla Knaus
Ruse M, Knaus, UG (2008) The role of small Rho GTPases in TLR signaling. Methods in Signal Transduction Series: CRC.  
Professor Prem Puri
Puri et al (2009) Pediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg. Available Online  
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Book Chapters
Professor Mohamed Al-Rubeai
Browne S. M. and Al-Rubeai M. (2009) 'Selection Methods for High-Producing Mammalian Cell Lines' In: Cell Engineering: Cell Line development. Berlin: Springer.  
Melero-Martin J. M., Santhalingam S., Al-Rubeai M. (2009) 'Methodology for optimal in vitro cell expansion in tissue engineering' In: Bioreactor Systems for Tissue Engineering. Berlin: Springer-Verlag. Available Online  
Dr Marguerite Clyne
Stephen Carrington, Marguerite Clyne, Colm Reid, Eammon Fitzpatrick and Anthony Corfield (2009) 'Microbial interaction with mucus and mucins' In: Microbial Glycobiology. United Satates of America: Academic Press.  
Prof Michael Duffy
Duffy MJ (2009) 'Biomarkers in breast cancer: use in aiding diagnosis, determining prognosis and predicting response to therapy' In: Adit Ben-Baruch (eds). Breast Cancer: From Pathogenesis to Potential Therapeutic Modalities. Kerala, India: Transworld Research Network.  
Professor Michael J. Dunn
McManus C, Rose ML, Dunn MJ (2008) 'Diagnostic markers for monitoring heart transplant rejection' In: Clinical Proteomics: From Diagnosis to Therapy. Weinheim: Wiley-VCH.  
Donoghue P, Stastna M, Dunn MJ (2008) 'Protein separation by two-dimensional electrophoresis' In: Eyk JE, Dunn MJ (eds). Clinical Proteomics: From Diagnosis to Therapy. Weinheim: Wiley-VCH.  
Focking M, Pennington K, English J, Dunn MJ, Cotter D (2008) 'Proteomics provides insights into major psychiatric disorders' In: Clinical Proteomics: From Diagnosis to Therapy. Weinheim: Wiley-VCH.  
Professor Patrick Guiry
M. O. Fitzpatrick; A. G. Coyne; P. J. Guiry, (2009) 'Ligand Design for the Intermolecular Asymmetric Heck Reaction' In: Martin Oestrich (eds). The Mizoroki-Heck Reaction. Chichester, United Kingdom: Wiley. Available Online  
Dr Tara McMorrow
McMorrow T., Campbell E., Slattery C., Ryan M.P. (2008) 'Altered gene expression and molecular Mechanisms modulating epithelial-mesenchymal transition in human renal epithelial cells' In: Paul J Higgins (eds). Human Epithelial Tumor Cell Plasticity: Implications for Cancer Progression and Metastasis. India: Research Signpost.  
Dr Jens Erik Nielsen
Nielsen JE (2009) 'Analyzing Enzymatic pH ActivityProfiles and Protein TitrationCurves Using Structure-Based pKaCalculations and TitrationCurve Fitting' In: Michael L. Johnson and Ludwig Brand (eds). Methods in Enzymology, Volume 454. Elsevier. Available Online  
Nielsen JE (2008) 'Analyzing Protein NMR pH-Titration Curves' In: A. Wheeler and David C. Spellmeyer (eds). Annual Reports in Computational Chemistry, Volume 4. Amsterdam: Elsevier.  
Professor Ronan O'Connell
O'Connell PR (2008) 'ANAL CANCER' In: Herold A, Matzel K, Lehur PA, O'Connell PR (eds). EUROPEAN MANUAL OF COLOPROCTOLOGY. Frankfurt: Springer.  
Professor William Powderly
Powderly WG. (2009) 'Oral Fungal Infections' In: E. Anaissie, M. McGinnis, M. Pfaller (eds). Clinical Mycology. Philadelphia: Churchill Livingstone.  
Overton ET, Powderly WG (2009) 'Treatment of persons infected with human immunodeficiency virus' In: Palliative Medicine. Philadelphia: Saunders, Elsevier.  
Powderly W, Overton ET (2008) 'Treatment of persons infected with the human immunodeficiency virus' In: Walsh D (eds). Palliative Medicine. Philadelphia: Saunders Elsevier.  
Professor Prem Puri
P. Puri and J. Gillick (2009) 'Preoperative assessment and Vascular Access' In: P. Puri and M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
S. Paran and P. Puri (2009) 'Teratomas' In: P. Puri and M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
P. Puri and S. Paran (2009) 'Prune belly syndrome' In: P. Puri and M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
P. Puri (2009) 'Hirshprung's disease and variants' In: P. Puri and M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
P. Puri and N. Nakazawa (2009) 'Congenital Diaphragmatic Hernia' In: P. Puri and M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
P. Puri and S. Paran (2009) 'Duplication anomalies' In: P. Puri and M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
P. Puri and S. Paran (2009) 'Birth Trauma' In: P. Puri and M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
P. Puri (2009) 'Vesicoureteral reflux' In: P. Puri and M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
P. Puri and A. Mortell (2009) 'Duplications of the alimentary tract' In: P. Puri and M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
P. Puri and U. Rolle (2009) 'Transport of the surgical neonate' In: P. Puri & M. Hollwarth (eds). Paediatric Surgery: Diagnosis & Management. Heidelberg: Springer Berlin Heidelberg.  
P. Puri (2008) 'Birth Injuries' In: D Gupta (eds). Neonatal Surgery. Dehli: Jaypee Brothers Medical Publishers (P) Ltd.  
P. Puri (2008) 'Vesicoureteral Reflux' In: A. Pierro & M. Davenport (eds). Oxford Handbook of Paediatric Surgery. UK: Oxford University Press.  
Dr Emma C Teeling
Teeling, E.C. (2009) 'Chiroptera' In: Time Tree of Life. Oxford: Oxford University Press.  
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Books Edited
Professor Mohamed Al-Rubeai
M. Al-Rubeai (Ed.). (2009) Cell Engineering Vol. 6: Cell Line Development. Springer.  
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Peer Reviewed Journals
Professor Mohamed Al-Rubeai
Woolley J. F. and Al-Rubeai M (2009) 'The isolation and identification of a secreted biomarker associated with cell stress in serum-free CHO cell culture. Biotechnology and Bioengineering'. Biotechnology and Bioengineering, 104 :590-600.  
Boehm D., Murphy W. G. and Al-Rubeai M (2009) 'The potential of human peripheral blood derived CD34+ cells for ex vivo red blood cell production'. Journal of Biotechnology .  
Sandhu K. S. and Al-Rubeai M. (2009) 'The effect of Bcl-2, YAMA, and XIAP over-expression on apoptosis and adenovirus production in HEK293 cell line'. Biotechnology and Bioengineering, 104 :752-765.  
Kuystermans D. and Al-Rubeai M. (2009) 'cMyc increases cell number through uncoupling of cell division from cell size in CHO cells'. BMC Biotechnology, 9 . Available Online  
Woolley J. F. and Al-Rubeai M (2009) 'The application of SELDI-TOF mass spectrometry to mammalian cell culture'. Biotechnology Advances, 104 :590-600.  
Khoo S. H. G. and Al-Rubeai M. (2009) 'Metabolic characterization of a hyper-productive state in an antibody producing NS0 myeloma cell line'. Metabolic Engineering, 11 :199-211.  
Khoo S. H. G. and Al-Rubeai M. (2009) 'Detailed understanding of enhanced specific antibody productivity in NS0 myeloma cells'. Biotechnology and Bioengineering, 102 :188-199.  
Professor Alan Baird
Winter DC, Hogan AM, Collins D, Baird AW, (2009) 'Estrogen and gastrointestinal malignancy'. Molecular and cellular endocrinology, 1-2 (NA):19-24.  
Winter DC, Hogan AM, Kennelly R, Collins D, Baird AW, (2009) 'Oestrogen inhibits human colonic motility by a non-genomic cell membrane receptor-dependent mechanism'. The British Journal of Surgery, 7 (NA):817-822.  
O'Farrelly C, Nemeth E, Baird AW, (2009) 'Microanatomy of the liver immune system'. Seminars in immunopathology .  
Winter DC, Gallagher TK, Baird AW, (2009) 'Constitutive basal and stimulated human small bowel contractility is enhanced in obesity'. Annals of surgical innovation and research, (NA).  
Winter DC, Hogan AM, Gallagher TK, Rory K, Baird AW, (2009) 'Gastric applications of electrical field stimulation'. Surgical laparoscopy, endoscopy & percutaneous techniques, 2 (NA):85-89.  
Irwin JA, Ryan MT, Baird AW, Mulholland CW, (2009) 'Practical classes: a platform for deep learning? Overall context in the first-year veterinary curriculum'. Journal of veterinary medical education, 2 (NA):180-185.  
Keely SJ, Baird AW, Skelly MM, O'Donoghue DP, Barrett KE, (2008) 'Bradykinin regulates human colonic ion transport in vitro'. British journal of pharmacology, 155 (4):558-566.  
Dr John Andrew Baugh
Merk M, Baugh J, Zierow S, Leng L, Pal U, Lee SJ, Ebert AD, Mizue Y, Trent JO, Mitchell R, Nickel W, Kavathas PB, Bernhagen J, Bucala R (2009) 'The Golgi-associated protein p115 mediates the secretion of macrophage migration inhibitory factor'. Journal of Immunology .  
Martos R, Baugh J, Ledwidge M, O'Loughlin C, Murphy NF, Conlon C, Patle A, Donnelly SC, McDonald K (2009) 'Diagnosis of heart failure with preserved ejection fraction: improved accuracy with the use of markers of collagen turnover'. European Journal of Heart Failure .  
Dr Orina Belton
Belton O, McClelland S, Gawaz M, Kennerknecht E, Konrad CS, Sauer S, Schuerzinger K, Massberg S, Fitzgerald DJ, (2009) 'Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse'. Atherosclerosis, 202 (1):84-91.  
Dr Oliver Blacque
Bialas NJ, Inglis PN, Li C, Robinson JF, Parker JD, Healey MP, Davis EE, Inglis CD, Toivonen T, Cottell DC, Blacque OE, Quarmby LM, Katsanis N, Leroux MR. (2009) 'Functional interactions between the ciliopathy-associated Meckel syndrome 1(MKS1) protein and two novel MKS1-related (MKSR) proteins'. Journal of Cell Science, 122 (5):611-624.  
Dr Billy Bourke
Bourke B, Rowland M, Fleming P, (2009) 'Looking in the mouth for Crohn's disease'. Inflammatory bowel diseases .  
Professor David Brayden
Jones, M., Mantovani, G., Ryan, S. M., Wang, X., Brayden, D. J., & Haddleton, D. M. (2009) 'Phosphine-mediated one-pot thiol-ene ¿click¿ approach to polymer¿protein conjugates'. Chemical Communications, 35 :5272-5274. Available Online  
Sayers, C.T., Mantovani, G., Ryan, S. M., Randev, R.K., Keiper, O., Leszczyszyn, O. I., Blindauer, C., Brayden, D. J., & Haddleton, D. M. (2009) 'Site-specific N-terminus conjugation of poly(mPEG1100) methacrylates to salmon calcitonin: synthesis and preliminary biological evaluation. Site-specific N-terminus conjugation of poly(mPEG1100) methacrylates to salmon calcitonin: synthesis and preliminary biological evaluation'. Soft Matter, 5 :3038-3038.  
Callanan JJ, Fletcher NF, Bexiga MG, Brayden DJ, Brankin B, Willett BJ, Hosie MJ, Jacque JM, (2009) 'Lymphocyte migration through the blood brain barrier (BBB) in feline immunodeficiency virus infection is significantly influenced by the pre-existence of virus and TNF-alpha within the CNS: studies using an in vitro feline BBB model'. Neuropathology and applied neurobiology .  
Brayden DJ, Keely S, Ryan SM, Haddleton DM, Limer A, Mantovani G, Murphy EP, Colgan SP, (2009) 'Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers'. Journal of controlled release : official journal of the Controlled Release Society, 135 (1):35-43.  
Brayden DJ, Ryan SM, Wang X, Mantovani G, Sayers CT, Haddleton DM, (2009) 'Conjugation of salmon calcitonin to a combed-shaped end functionalized poly(poly(ethylene glycol) methyl ether methacrylate) yields a bioactive stable conjugate'. Journal of controlled release : official journal of the Controlled Release Society, 135 (1):51-59.  
Brayden DJ, Feighery LM, Smith P, O'Mahony L, Fallon PG, (2008) 'Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease'. Digestive diseases and sciences, 53 (9):2495-2506.  
Dr Lorraine Brennan
Brennan L, (2008) 'Session 2: Personalised nutrition. Metabolomic applications in nutritional research'. The Proceedings of the Nutrition Society, 67 (4):404-408.  
4. Baccini M, Bachmaier EM, Biggeri A, Boekschoten MV, Bouwman FG, Brennan L, Caesar R, Cinti S, Coort SL, Crosley K, Daniel H, Drevon CA, Duthie S, Eijssen L, Elliott RM, van Erk M, Evelo C, Gibney M, Heim C, Horgan GW, Johnson IT, Kelder T, Kleemann R, Kooistra T, van Iersel MP, Mariman EC, Mayer C, McLoughlin G, Müller M, Mulholland F, van Ommen B, Polley AC, Pujos-Guillot E, Rubio-Aliaga I, Roche HM, de Roos B, Sailer M, Tonini G, Williams LM, de Wit N; For the NuGO PPS Team. (2008) 'The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation'. Genes & Nutrition, 3 .  
Turner DL, PaixaÌ¿o VB, Salgueiro CA, Brennan L, Reid GA, Chapman SK, (2008) 'The Solution Structure of a Tetraheme Cytochrome from Shewanella frigidimarina Reveals a Novel Family Structural Motif'. Biochemistry .  
Professor Geraldine Butler
Butler G, Rasmussen MD, Lin MF, Santos MA, Sakthikumar S, Munro CA, Rheinbay E, Grabherr M, Forche A, Reedy JL, Agrafioti I, Arnaud MB, Bates S, Brown AJ, Brunke S, Costanzo MC, Fitzpatrick DA, de Groot PW, Harris D, Hoyer LL, Hube B, Klis FM, Kodira C, Lennard N, Logue ME, Martin R, Neiman AM, Nikolaou E, Quail MA, Quinn J, Santos MC, Schmitzberger FF, Sherlock G, Shah P, Silverstein KA, Skrzypek MS, Soll D, Staggs R, Stansfield I, Stumpf MP, Sudbery PE, Srikantha T, Zeng Q, Berman J, Berriman M, Heitman J, Gow NA, Lorenz MC, Birren BW, Kellis M,Cuomo CA. (2009) 'Evolution of pathogenicity and sexual reproduction in eight Candida genomes'. Nature, 459 :657-662.  
Dr Gerard Cagney
Cagney G, Wong JW, McRedmond JP, (2009) 'Activity profiling of platelets by chemical proteomics'. Proteomics, 9 (1):40-50.  
Shields DC, Casey FP, Cagney G, Krogan NJ, (2008) 'Optimal stepwise experimental design for pairwise functional interaction studies'. Bioinformatics, (NA).  
Shields DC, Casey FP, Cagney G, Krogan NJ, (2008) 'Optimal stepwise experimental design for pairwise functional interaction studies'. Bioinformatics .  
Professor Sean Callanan
Callanan JJ, Nolan CM, O'Sullivan FM, Brabazon DC, (2009) 'Genomic imprinting in Canis familiaris'. Reproduction in Domestic Animals, 44 Suppl 2 :16-21.  
O'Farrelly C, Chapwanya A, Meade KG, Doherty ML, Callanan JJ, Mee JF, (2009) 'Histopathological and molecular evaluation of Holstein-Friesian cows postpartum: toward an improved understanding of uterine innate immunity'. Theriogenology, 71 (9):1396-1407.  
O'Farrelly C, Shaughnessy RG, Meade KG, Cahalane S, Allan B, Reiman C, Callanan JJ, (2009) 'Innate immune gene expression differentiates the early avian intestinal response between Salmonella and Campylobacter'. Veterinary Immunology and Immunopathology .  
Mally A, Sieber M, Hoffmann D, Adler M, Vaidya VS, Clement M, Bonventre JV, Zidek N, Rached E, Amberg A, Callanan JJ, Dekant W, (2009) 'Comparative analysis of novel noninvasive renal biomarkers and metabonomic changes in a rat model of gentamicin nephrotoxicity'. Toxicological sciences : an official journal of the Society of Toxicology, 109 (2):336-349.  
McLean WH, Fallon PG, Sasaki T, Sandilands A, Campbell LE, Saunders SP, Mangan NE, Callanan JJ, Kawasaki H, Shiohama A, Kubo A, Sundberg JP, Presland RB, Fleckman P, Shimizu N, Kudoh J, Irvine AD, Amagai M, (2009) 'A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming'. Nature Genetics, 41 (5):602-608.  
Callanan JJ, Fletcher NF, Bexiga MG, Brayden DJ, Brankin B, Willett BJ, Hosie MJ, Jacque JM, (2009) 'Lymphocyte migration through the blood brain barrier (BBB) in feline immunodeficiency virus infection is significantly influenced by the pre-existence of virus and TNF-alpha within the CNS: studies using an in vitro feline BBB model'. Neuropathology and applied neurobiology .  
Duggan V, Bryan J, Puggioni A, McAllister H, Callanan J, Katz L, (2009) 'Thrombosis of the pulmonary artery in a yearling thoroughbred colt'. Journal of Veterinary Internal Medicine, 23 (1):215-219.  
Nally JE, Monahan AM, Callanan JJ, (2008) 'Proteomic analysis of Leptospira interrogans shed in urine of chronically infected hosts'. Infection and Immunity, 76 (11):4952-4958.  
Gallagher WM, Mulrane L, Rexhepaj E, Penney S, Callanan JJ, (2008) 'Automated image analysis in histopathology: a valuable tool in medical diagnostics'. EXPERT REV MOL DIAGN, 8 (6):707-725.  
Dr Marguerite Clyne
Bourke B, Corcionivoschi N, Clyne M, Lyons A, Elmi A, Gundogdu O, Wren BW, Dorrell N, Karlyshev AV, (2009) 'Campylobacter jejuni cocultured with epithelial cells reduces surface capsular polysaccharide expression'. Infection and Immunity, 77 (5):1959-1967.  
Clyne M, Reeves EP, Ali T, Leonard P, Hearty S, O'Kennedy R, May FE, Westley BR, Josenhans C, Rust M, Suerbaum S, Smith A, Drumm B, (2008) 'Helicobacterpylori Lipopolysaccharide Interacts With TFF1 in a pH-Dependent Manner'. Gastroenterology .  
Dr John Crean
Godson C, Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, (2008) 'Regulation and consequences of differential gene expression in diabetic kidney disease'. Biochemical Society transactions, Pt 5 (NA):941-945.  
Dr Paul Crossey
Duncan ER, Crossey PA, Walker S, Anilkumar N, Poston L, Douglas G, Ezzat VA, Wheatcroft SB, Shah AM, Kearney MT (2008) 'Effect of endothelium-specific insulin resistance on endothelial function in vivo'. Diabetes, 57 (12):3307-3314.  
Professor Mark Crowe
Cavestany D. Viñoles C, Crowe MA, La Manna A and Mendoza A (2009) 'Effect of prepartum diet on postpartum ovarian activity in Holstein cows in a pasture-based dairy system'. Animal Reproduction Science, 114 :1-13.  
Piebes AHG, van de Griend B, Rijnders MJW, de Vries IJR, van der Weijden GC, Crowe MA and Gruys E (2009) 'Subacute ruminal acidosis, claw problems and infertility in (high producing) milk cows (article in Dutch)'. Tijdschr Diergeneeskd, 134 :486-490.  
Crowe MA, Lane EA, Sweeney T, Ryan M, Roche JF, (2009) 'Relationship between serum gonadotropins and pituitary immunoreactive gonadotropins and steroid receptors during the first FSH increase of the estrous cycle and following steroid treatment in heifers'. Animal Reproduction Science, 1-2 (NA):66-82.  
Crowe MA, Beltman ME, Lonergan P, Diskin MG, Roche JF, (2009) 'Effect of progesterone supplementation in the first week post conception on embryo survival in beef heifers'. Theriogenology, 71 (7):1173-1179.  
MA Crowe (2008) 'Resumpyion of ovarian cycliclty in post-partum beef and dairy cows'. Reproduction in Domestic Animals, 43 (Suppl. 5):20-28.  
Prof Michael Duffy
Gallagher WM, Lanigan F, McKiernan E, Brennan DJ, Hegarty S, Millikan RC, McBryan J, Jirstrom K, Landberg G, Martin F, Duffy MJ, (2009) 'Increased claudin-4 expression is associated with poor prognosis and high tumour grade in breast cancer'. International Journal of Cancer, 124 (9):2088-2097.  
O'Donovan N, Browne BC, O'Brien N, Duffy MJ, Crown J, (2009) 'HER-2 signaling and inhibition in breast cancer'. Current Cancer Drug Targets, 9 (3):419-438.  
McGowan PM, Duffy MJ, McKiernan E, O'Donovan N, (2009) 'The role of ADAMs in disease pathophysiology'. Clinica chimica acta; international journal of clinical chemistry, 403 (1-2):31-36.  
McGowan PM, Duffy MJ, McKiernan E, O'Donovan N, (2009) 'Role of ADAMs in cancer formation and progression'. Clinical Cancer Research, 15 (4):1140-1144.  
Schmitt M, Duffy MJ, Napieralski R, Martens JW, Span PN, Spyratos F, Sweep FC, Brunner N, Foekens JA, (2009) 'Methylated genes as new cancer biomarkers'. EUROPEAN JOURNAL OF CANCER, 45 (3):335-346.  
Duffy MJ, Markey GC, Cullen R, Diggin P, Hill AD, Mc Dermott EW, O'Higgins NJ, (2009) 'Estrogen receptor-beta mRNA is associated with adverse outcome in patients with breast cancer'. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 30 (4):171-175.  
Martens JW, Span PN, Sieuwerts AM, Heuvel JJ, Spyratos F, Duffy MJ, Eppenberger-Castori S, Vacher S, O'Brien K, McKiernan E, Pierce A, Vuaroqueaux V, Foekens JA, Sweep FC, (2009) 'Harmonisation of multi-centre real-time reverse-transcribed PCR results of a candidate prognostic marker in breast cancer: an EU-FP6 supported study of members of the EORTC - PathoBiology Group'. EUROPEAN JOURNAL OF CANCER, 45 (1):74-81.  
Diamandis EP, Sturgeon CM, Duffy MJ, Stenman UH, Lilja H, Brünner N, Chan DW, Babaian R, Bast RC Jr, Dowell B, Esteva FJ, Haglund C, Harbeck N, Hayes DF, Holten-Andersen M, Klee GG, Lamerz R, Looijenga LH, Molina R, Nielsen HJ, Rittenhouse H, Semjonow A, Shih IeM, Sibley P, Sölétormos G, Stephan C, Sokoll L, Hoffman BR, (2008) 'National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers'. Clinical chemistry, 54 (12):1-79.  
Duffy MJ, McKiernan E, O'Brien K, Grebenchtchikov N, Geurts-Moespot A, Sieuwerts AM, Martens JW, Magdolen V, Evoy D, McDermott E, Crown J, Sweep FC, (2008) 'Protein kinase Cdelta expression in breast cancer as measured by real-time PCR, western blotting and ELISA'. Cancer, 99 (10):1644-1650.  
Crown J, Duffy MJ, (2008) 'A personalized approach to cancer treatment: how biomarkers can help'. Clinical chemistry, 54 (11):1770-1779.  
Professor Michael J. Dunn
McManus, C. A.,Donoghue, P. M.,Dunn, M. J. (2009) 'A fluorescent codetection system for immunoblotting and proteomics through ECL-Plex and CyDye labeling'. Methods Mol Biol, 536 :515-26. Available Online  
Behan, A. T.,Byrne, C.,Dunn, M. J.,Cagney, G.,Cotter, D. R. (2009) 'Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression'. Mol Psychiatry, 14 (6):601-13. Available Online  
Trott, D.,McManus, C. A.,Martin, J. L.,Brennan, B.,Dunn, M. J.,Rose, M. L. (2009) 'Effect of phosphorylated hsp27 on proliferation of human endothelial and smooth muscle cells'. Proteomics, 9 (12):3383-94. Available Online  
Rose, M. L.,Dunn, M. J. (2009) 'Biomarkers of rejection: are we any closer to the Philosopher's Stone?'. Transplantation, 88 (4):453-4. Available Online  
Pennington, K.,Focking, M.,McManus, C. A.,Pariante, C. M.,Dunn, M. J.,Cotter, D. R. (2009) 'A proteomic investigation of similarities between conventional and herbal antidepressant treatments'. J Psychopharmacol, 23 (5):520-30. Available Online  
Govender P, Dunn MJ, Donnelly SC (2009) 'Proteomics and the lung: Analysis of bronchoalveolar lavage fluid'. Proteomics Clinical Applications, 2 :1044-1051.  
English, J. A.,Dicker, P.,Focking, M.,Dunn, M. J.,Cotter, D. R. (2009) '2-D DIGE analysis implicates cytoskeletal abnormalities in psychiatric disease'. Proteomics, 9 (12):3368-82. Available Online  
Eisenacher, M.,Martens, L.,Hardt, T.,Kohl, M.,Barsnes, H.,Helsens, K.,Hakkinen, J.,Levander, F.,Aebersold, R.,Vandekerckhove, J.,Dunn, M. J.,Lisacek, F.,Siepen, J. A.,Hubbard, S. J.,Binz, P. A.,Bluggel, M.,Thiele, H.,Cottrell, J.,Meyer, H. E.,Apweiler, R.,Stephan, C. (2009) 'Getting a grip on proteomics data - Proteomics Data Collection (ProDaC)'. Proteomics, 9 (15):3928-33. Available Online  
Bell AW et al. (2009) 'A HUPO test sample study reveals common problems in mass spectrometry-based proteomics'. Nature Methods, 6 :423-430.  
Donoghue, P. M.,Hughes, C.,Vissers, J. P.,Langridge, J. I.,Dunn, M. J. (2008) 'Nonionic detergent phase extraction for the proteomic analysis of heart membrane proteins using label-free LC-MS'. Proteomics, 8 (18):3895-905. Available Online  
Radwan, M.,Miller, I.,Grunert, T.,Marchetti-Deschmann, M.,Vogl, C.,O'Donoghue, N.,Dunn, M. J.,Kolbe, T.,Allmaier, G.,Gemeiner, M.,Muller, M.,Strobl, B. (2008) 'The impact of tyrosine kinase 2 (Tyk2) on the proteome of murine macrophages and their response to lipopolysaccharide (LPS)'. Proteomics, 8 (17):3469-85. Available Online  
Pennington, K.,Dicker, P.,Dunn, M. J.,Cotter, D. R. (2008) 'Proteomic analysis reveals protein changes within layer 2 of the insular cortex in schizophrenia'. Proteomics, 8 (23-24):5097-107. Available Online  
Dunn MJ, Donoghue PM, Hughes C, Vissers JP, Langridge JI, (2008) 'Nonionic detergent phase extraction for the proteomic analysis of heart membrane proteins using label-free LC-MS'. Proteomics, 8 (18):3895-3905.  
Strobl B, Radwan M, Miller I, Grunert T, Marchetti-Deschmann M, Vogl C, O'Donoghue N, Dunn MJ, Kolbe T, Allmaier G, Gemeiner M, Müller M, (2008) 'The impact of tyrosine kinase 2 (Tyk2) on the proteome of murine macrophages and their response to lipopolysaccharide (LPS)'. Proteomics, 8 (17):3469-3485.  
Dr Giuliano Elia
Power, K. A.,McRedmond, J. P.,de Stefani, A.,Gallagher, W. M.,Gaora, P. O. (2009) 'High-throughput proteomics detection of novel splice isoforms in human platelets'. PLoS ONE, 4 (3). Available Online  
Keenan, J.,Elia, G.,Dunn, M.J.,Orr, D.F.,Pierscionek, B.K. (2009) 'Crystallin distribution patterns in concentric layers from toad eye lenses'. Proteomics, 9 .  
Bell, A. W.,Deutsch, E. W.,Au, C. E.,Kearney, R. E.,Beavis, R.,Sechi, S.,Nilsson, T.,Bergeron, J. J.,Beardslee, T. A.,Chappell, T.,Meredith, G.,Sheffield, P.,Gray, P.,Hajivandi, M.,Pope, M.,Predki, P.,Kullolli, M.,Hincapie, M.,Hancock, W. S.,Jia, W.,Song, L.,Li, L.,Wei, J.,Yang, B.,Wang, J.,Ying, W.,Zhang, Y.,Cai, Y.,Qian, X.,He, F.,Meyer, H. E.,Stephan, C.,Eisenacher, M.,Marcus, K.,Langenfeld, E.,May, C.,Carr, S. A.,Ahmad, R.,Zhu, W.,Smith, J. W.,Hanash, S. M.,Struthers, J. J.,Wang, H.,Zhang, Q.,An, Y.,Goldman, R.,Carlsohn, E.,van der Post, S.,Hung, K. E.,Sarracino, D. A.,Parker, K.,Krastins, B.,Kucherlapati, R.,Bourassa, S.,Poirier, G. G.,Kapp, E.,Patsiouras, H.,Moritz, R.,Simpson, R.,Houle, B.,Laboissiere, S.,Metalnikov, P.,Nguyen, V.,Pawson, T.,Wong, C. C.,Cociorva, D.,Semchuk, P. (2009) 'A HUPO test sample study reveals common problems in mass spectrometry-based proteomics'. Nat Methods . Available Online  
Carbone, A.,Gloghini, A.,Cabras, A.,Elia, G. (2009) 'The Germinal centre-derived lymphomas seen through their cellular microenvironment'. Br J Haematol, 145 (4):468-80. Available Online  
Carolan, J. C.,Fitzroy, C. I.,Ashton, P. D.,Douglas, A. E.,Wilkinson, T. L. (2009) 'The secreted salivary proteome of the pea aphid Acyrthosiphon pisum characterised by mass spectrometry'. Proteomics, 9 (9):2457-67. Available Online  

Carbone, A.,Gloghini, A.,Cabras, A.,Elia, G. (2009) 'Differentiating germinal center-derived lymphomas through their cellular microenvironment'. Am J Hematol . Available Online  
Bell, A.W. et al. (2009) 'A HUPO test sample study reveals common problems in mass spectrometry-based proteomics'. Nat Methods . Available Online  
Pennington, K.,Dicker, P.,Dunn, M. J.,Cotter, D. R. (2008) 'Proteomic analysis reveals protein changes within layer 2 of the insular cortex in schizophrenia'. Proteomics, 8 (23-24):5097-107. Available Online  
Elia G, (2008) 'Biotinylation reagents for the study of cell surface proteins'. Proteomics, 8 (19):4012-4024.  
Dawson KA, Lundqvist M, Stigler J, Elia G, Lynch I, Cedervall T, (2008) 'Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts'. Proceedings of the National Academy of Sciences of the United States of America, 38 (NA):14265-14270.  
Professor Alexander Evans
F Jimenez-Krassel, JK Folger, JLH Ireland, GW Smith, X Hou, JS Davis, P Lonergan, ACO Evans, and JJ Ireland (2009) 'Evidence that high variation in ovarian reserves of healthy young adults has a negative impact on the corpus luteum and endometrium during reproductive cycles of single-ovulating species'. Biology of Reproduction, 80 (6):1272-1281.  
NA Smith, FM Mc Auliffe, K Quinn, P Lonergan, ACO Evans. (2009) 'Transient high glycaemic intake in the last trimester of pregnancy increases offspring birth weight and postnatal growth rate in sheep'. British Journal of Obstetrics and Gynaecology, 116 (7):975-983.  
JJ Ireland, AE Zielak, F Jimenez-Krassel, J Folger, A Bettegowda, D Scheetz, S Walsh, F Mossa, PG Knight, GW Smith, P Lonergan, ACO Evans (2009) 'Variation in the Ovarian Reserve is linked to Alterations in Intrafollicular Estradiol Production and Ovarian Biomarkers of Follicular Differentiation and Oocyte Quality in Cattle'. Biology of Reproduction, 80 (5):954-964.  
JLH Ireland, D Scheetz, F Jimenez-Krassel, AP Themmen, F Ward, P Lonergan, GW Smith, GI Perez, ACO Evans, JJ Ireland. (2008) 'Antral follicle count reliably predicts number of morphologically healthy oocytes and follicles in ovaries of young adult cattle'. Biology of Reproduction, 79 (6):1219-1225.  
MA de Feu, J Patton, ACO Evans, P Lonergan, ST Butler. (2008) 'The effect of strain of Holstein-Fresian cow on size of ovarian structures, periovulatory circulating steroid concentrations, and embryo quality following superovulation'. Theriogenology, 70 (7):1101-1110.  
de Feu, M.A., Patton, J., Evans, A.C.O., Lonergan, P., Butler, S.T. (2008) 'The effect of strain of Holstein-Friesian cow on size of ovarian structures, periovulatory circulating steroid concentrations, and embryo quality following superovulation'. Theriogenology, 70 :1101-1110.  
KE Ryan, C Glister, P Lonergan, F Martin, PG Knight, ACO Evans (2008) 'Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vivo and in vitro studies in cattle and sheep'. Journal of Ovarian Research, 1 (2):1-13.  
PAR Hawkens, ACO Evans and AP Beard. (2008) 'Prior exposure of maiden ewes to rams enhances their behavioural interactions with rams but is not a pre-requisite to their endocrine response to the ram effect'. Animal Reproduction Science, 108 :13-21.  
Dr Paul Evans
Evans P, Klein JE, Müller-Bunz H, (2009) 'Studies concerning the electrophilic amino-alkene cyclisation for the synthesis of bicyclic amines'. Organic &Amp; Biomolecular Chemistry, 7 (5):986-995.  
Y. Kavanagh, C. M. Chaney, J. Muldoon and P. Evans (2008) 'Iridium Catalyst Mediated Isomerisation-Cyclisation of Pauson-Khand Derived Bicyclic Allylic Alcohols'. Journal of Organic Chemistry, 73 .  
J. Klein, H. Müller-Bunz, Y. Ortin and P. Evans (2008) 'Formation of Cyclic Sulfonamides via an Unusual 8-endo -trig Heck Olefination Reaction0'. Tetrahedron Letters, 49 .  
Dr Neil Ferguson
Neuweiler, H., Sharpe, T. D., Rutherford, T. J., Johnson, C. M., Allen, M. D., Ferguson, N. & Fersht, A. R. (2009) 'The folding mechanism of BBL: Plasticity of transition state structure observed within an ultrafast folding protein family'. Journal of Molecular Biology, 390 :1060-1073.  
Arbely, A., Rutherford, T. J., Sharpe, T. D., Ferguson, N. & Fersht, A. R. (2009) 'Downhill versus barrier-limited folding. 1. Energetic and structural basis for the perturbation of the protein BBL on protonation of a histidine of unusually low pKa'. Journal of Molecular Biology, 387 :986-992.  
Neuweiler, H., Sharpe, T. D., Johnson, C. M., Teufel, D. P., Ferguson, N. & Fersht, A. R. (2009) 'Downhill versus barrier limited folding of BBL. 2. Mechanistic Insights from kinetics of folding monitored by independent tryptophan probes'. Journal of Molecular Biology, 387 :975-985.  
Professor Oliver Fitzgerald
Bresnihan B, Pontifex E, Thurlings RM, Vinkenoog M, El-Babalawy H, Fearon U, Fitzgerald O, Gerlag DM, Rooney T, van de Sande MG, Veale D, Vos K, Tak PP (2009) 'Synovial tissue sublining CD68 expression is a biomarker of therapeutic response in rheumatoid arthritis clinical trials: consistency across centers'. Journal of Rheumatology .  
Syversen SW, Landewe R, van der Heijde D, Bathon JM, Boers M, Bykerk VP, Fitzgerald O, Gladman DD, Garnero P, Geusens P, El-Gabalawy H, Inman RD, Kraus V, Kvien TK, Mease PJ, Ostergaard M, Ritchlin CJ, Tak PP, Taylor WJ, Maksymowych WP (2009) 'Testing of the OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage in rheumatoid arthritis: a systematic literature search on 5 candidate biomarkers'. Journal of Rheumatology .  
Maksymowych WP, Fitzgerald O, Wells GA, Gladman DD, Landewe R, Ostergaard M, Taylor WJ, Christensen R, Tak PP, Boers M, Syversen SW, Bathon JM, Ritchlin CJ, Mease PJ, Mykerk VP, Garnero P, Geusens P, El-Gabalawy H, Aletaha D, Inman RD, Kraus VB, Kvien TK, van der Heijde D (2009) 'Proposal for levels of evidence schema for validation of a soluable biomarker reflecting damage endpoints in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, and recommendations for study design'. Journal of Rheumatology .  
Maksymowych WP, Landewé R, Tak PP, Ritchlin CJ, Ostergaard M, Mease PJ, El-Gabalawy H, Garnero P, Gladman DD, Fitzgerald O, Aletaha D, Bykerk VP, Bathon JM, Syversen SW, Boers M, Geusens P, Inman RD, Kraus VB, Kvien TK, Taylor WJ, Wells GA, van der Heijde D (2009) 'Reappraisal of OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage endpoints in rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: the OMERACT 9 v2 criteria'. Journal of Rheumatology .  
Moran EM, Mullan R, McCormick J, Connolly M, Sullivan O, Fitzgerald O, Bresnihan B, Veale DJ, Fearon U (2009) 'Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis'. Arthritis Research and Therapy .  
Murphy G, Coughlan R, Devlin J, FitzGerald O, McCarthy G (2009) 'Recommendations for the therapeutics of methotrexate in rheumatoid arthritis'. Irish Medical Journal .  
Rooney T, Roux-Lombard P, Veale DJ, Fitzgerald O, Dayer JM, Bresnihan B (2009) 'Synovial tissue and serum biomarkers of disease activity, therapeutic response and radiographic progression. analysis of a proof-of-concept randomized clinical trial of cytokine blockade'. Annals of Rheumatic Diseases .  
Becker K, Fitzgerald O, Green AJ, Keogan M, Newbury-Ecob R, Greenhalgh L, Withers S, Hollox EJ, Aldred PM, Armour JA (2009) 'Constitutional trisomy 8 and Behçet syndrome'. American Journal of Medical Genetics .  
Fitzgerald O, Winchester R (2009) 'Psoriatic arthritis: from pathogenesis to therapy'. Arthritis Research and Therapy .  
French HP, Cusack T, Brennan A, White B, Gilsenan C, Fitzpatrick M, O'Connell P, Kane D, Fitzgerald O, McCarthy GM (2009) 'Exercise and manual physiotherapy arthritis research trial (EMPART): a multicentre randomised controlled trial'. BMC Musculoskeletal Disorders .  
Martin J, Walsh C, Gibbs A, McDonnell T, Fearon U, Keane J, Codd MB, Dodd JD, Veale D, Fitzgerald O, Bresnihan B (2009) 'Comparison of interferon-{gamma}-release assays and conventional screening tests before tumour necrosis factor-{alpha} blockade in patients with inflammatory arthritis'. Annals of Rheumatic Diseases .  
Pearman L, Last J, Fitzgerald O, Veale D, Joyce M, Rainford L, McEntee M, McNulty J, Thomas E, Ryan J, McGee A, Toomey D'Helft R, Lowe J, Brennan PC (2009) 'Rheumatoid arthritis: a novel radiographic projection for hand assessment'. British Journal of Radiology .  
Doran JP, Alraqi S, Callanan I, Fitzgerald O, Bresnihan B, Veale DJ (2009) 'An audit of hospital based outpatient infusions and a pilot program of community-based monoclonal antibody infusions'. IRISH JOURNAL OF MEDICAL SCIENCE .  
Murphy E, Roux-Lombard P, Rooney T, Fitzgerald O, Dayer JM, Bresnihan B (2008) 'Serum levels of tissue inhibitor of metalloproteinase-1 and periarticular bone loss in early rheumatoid arthritis'. Clinical Rheumatology .  
Ritchlin CT, Kavanaugh A, Gladman DD, Mease PJ, Helliwell P, Boehncke WH, de Vlam K, Fiorentino D, Fitzgerald O, Gottlieb AB, McHugh N, Nash PT, Qureshi A, Soriano ER, Taylor WJ (2008) 'Treatment recommendations for psoriatic arthritis'. Annals of Rheumatic Diseases .  
Professor William Gallagher
Gallagher WM, Lanigan F, McKiernan E, Brennan DJ, Hegarty S, Millikan RC, McBryan J, Jirstrom K, Landberg G, Martin F, Duffy MJ, (2009) 'Increased claudin-4 expression is associated with poor prognosis and high tumour grade in breast cancer'. International Journal of Cancer, 9 (NA):2088-2097.  
Borrebaeck CA, Brennan DJ, Ek S, Doyle E, Drew T, Foley M, Flannelly G, O'Connor DP, Gallagher WM, Kilpinen S, Kallioniemi OP, Jirstrom K, O'Herlihy C, (2009) 'The transcription factor Sox11 is a prognostic factor for improved recurrence-free survival in epithelial ovarian cancer'. EUROPEAN JOURNAL OF CANCER, 45 (8):1510-1517.  
Ponten F, Strömberg S, Agnarsdóttir M, Magnusson K, Rexhepaj E, Bolander A, Lundberg E, Asplund A, Ryan D, Rafferty M, Gallagher WM, Uhlen M, Bergqvist M, (2009) 'Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma'. JOURNAL OF PROTEOME RESEARCH, 4 (NA):1639-1646.  
Koenig J, Gallagher WM, Tweats D, (2009) 'Omic profiling for drug safety assessment: current trends and public-private partnerships'. Drug Discovery Today, 14 (7-8):337-342.  
Gallagher WM, Gremel G, Rafferty M, Lau TY, (2009) 'Identification and functional validation of therapeutic targets for malignant melanoma'. Critical reviews in oncology/hematology, 72 (3):194-214.  
Gallagher WM, Mulrane L, Rexhepaj E, Penney S, Callanan JJ, (2008) 'Automated image analysis in histopathology: a valuable tool in medical diagnostics'. EXPERT REV MOL DIAGN, 6 (NA):707-725.  
Gallagher WM, Rexhepaj E, Brennan DJ, Holloway P, Kay E, McCann AH, Landberg G, Duffy MJ, Jirstrom K, (2008) 'Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of estrogen and progesterone receptor levels in breast cancer'. Breast cancer research : BCR, 10 (5).  
Lujambio A, Calin GA, Villanueva A, Ropero S, Sánchez-Céspedes M, Blanco D, Montuenga LM, Rossi S, Nicoloso MS, Faller WJ, Gallagher WM, Eccles SA, Croce CM, Esteller M (2008) 'A microRNA DNA methylation signature for human cancer metastasis'. PNAS, 105 (36):13556-13561.  
O'Riordan A, Johnston O, McMorrow T, Wynne K, Maguire P, Hegarty JE, McCormick A, Watson AJ, Cagney G, Gallagher WM, Ryan MR (2008) 'Identification of Apolipoprotein AI as a serum biomarker of chronic kidney disease in liver transplant recipients, using proteomic techniques'. Proteomics Clinical Applications, 2 (9):1338-1348.  
Professor Catherine Godson
Brazil DP, Roxburgh SA, Kattla JJ, Curran SP, O'Meara YM, Pollock CA, Goldschmeding R, Godson C, Martin F, (2009) 'Allelic depletion of grem1 attenuates diabetic kidney disease'. Diabetes, 58 (7):1641-1650.  
Godson C, Decker Y, McBean G, (2009) 'Lipoxin A4 inhibits IL-1beta-induced IL-8 and ICAM-1 expression in 1321N1 human astrocytoma cells'. American journal of physiology. Cell physiology, 296 (6):1-7.  
Hickey FB, Ryan A, Murphy M, Godson C, (2009) 'Diabetes mellitus and apoptosis: inflammatory cells'. Apoptosis .  
Godson C, Maderna P, Baker N, O'Meara SJ, Scannell M, (2009) 'Lipoxin A4: anti-inflammatory and anti-angiogenic impact on endothelial cells'. Journal of Immunology, 182 (6):3819-3826.  
Godson C, Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, (2008) 'Regulation and consequences of differential gene expression in diabetic kidney disease'. Biochemical Society Transactions, 36 (Pt 5):941-945.  
Godson C, Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, (2008) 'Regulation and consequences of differential gene expression in diabetic kidney disease'. Biochemical Society transactions, Pt 5 (NA):941-945.  
Martin F, McArdle E, McMahon R, Schmid H, Kretzler M, Droguett A, Mezzano S, Brady HR, Furlong F, Godson C, Murphy M, Docherty NG, Griffin B, Howlin J, (2008) 'IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis'. J AM SOC NEPHROL, 9 (NA):1672-1680.  
Professor Stephen Gordon
Vordermeier M, Gordon SV, Hewinson AR. (2009) 'Antigen Mining to Define Mycobacterium bovis Antigens for the Differential Diagnosis of Vaccinated and Infected Animals: A VLA Perspective'. Transboundary and emerging diseases, 56 (6-7):240-247.  
Santangelo Mde L, Klepp L, Nunez-GarcÃia J, Blanco FC, Soria M, Garcia-Pelayo Mdel C, Bianco MV, Cataldi AA, Golby P, Jackson M, Gordon SV, Bigi F. (2009) 'Mce3R, a TetR-type transcriptional repressor, controls the expression of a regulon involved in lipid metabolism in Mycobacterium tuberculosis'. Microbiology (Reading, England), 155 (Pt 7):2245-2255.  
Smith NH, Hewinson RG, Kremer K, Brosch R, Gordon SV. (2009) 'Myths and misconceptions: the origin and evolution of Mycobacterium tuberculosis'. Nature reviews. Microbiology, 7 (7):537-544.  
Garcia Pelayo MC, Uplekar S, Keniry A, Mendoza Lopez P, Garnier T, Nunez Garcia J, Boschiroli L, Zhou X, Parkhill J, Smith N, Hewinson RG, Cole ST, Gordon SV (2009) 'A comprehensive survey of single nucleotide polymorphisms (SNPs) across Mycobacterium bovis strains and M. bovis BCG vaccine strains refines the genealogy and defines a minimal set of SNPs that separate virulent M. bovis strains and M. bovis BCG strains'. Infection and Immunity, 77 (5):2230-2238.  
Gordon SV, Bottai D, Simeone R, Stinear TP, Brosch R. (2009) 'Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants'. BioEssays : news and reviews in molecular, cellular and developmental biology .  
Muller B, Hilty M, Berg S, Garcia-Pelayo MC, Dale J, Boschiroli ML, Cadmus S, Naré B, Ngandolo R, Godreuil S, Diguimbaye-Djaibé C, Kazwala R, Bonfoh B, Njanpop-Lafourcade BM, Sahraoui N, Guetarni D, Aseffa A, Mekonnen MH, Rasolofo Razanamparany V, Ramarokoto H, Djønne B, Oloya J, Machado A, Mucavele C, Skjerve E, Portaels F, Rigouts L, Michel A, Müller A, Källenius G, van Helden PD, Hewinson RG, Zinsstag J, Gordon SV, Smith NH (2009) 'African 1; An Epidemiologically Important Clonal Complex of Mycobacterium bovis Dominant in Mali, Nigeria, Cameroon and Chad'. Journal of Bacteriology .  
Berg S, Firdessa R, Habtamu M, Gadisa E, Mengistu A, Yamuah L, Ameni G, Vordermeier M, Robertson BD, Smith NH, Engers H, Young D, Hewinson RG, Aseffa A, Gordon SV. (2009) 'The burden of mycobacterial disease in ethiopian cattle: implications for public health'. PLoS ONE, 4 (4).  
Wheeler PR, Brosch R, Coldham NG, Inwald JK, Hewinson RG, Gordon SV (2008) 'Functional analysis of a clonal deletion in an epidemic strain of Mycobacterium bovis reveals a role in lipid metabolism'. Microbiology (Reading, England), 154 (Pt 12):3731-3742.  
Ojo O, Sheehan S, Corcoran GD, Okker M, Gover K, Nikolayevsky V, Brown T, Dale J, Gordon SV, Drobniewski F, Prentice MB (2008) 'Mycobacterium bovis Strains Causing Smear-Positive Human Tuberculosis, Southwest Ireland'. Emerging infectious diseases, 14 (12):1931-1934.  
Gordon SV (2008) 'Bovine TB: stopping disease control would block all live exports'. Nature, 456 (7223).  
Professor Andrew Green
Lugtenberg D, Kleefstra T, Oudakker AR, Nillesen WM, Yntema HG, Tzschach A, Raynaud M, Rating D, Journel H, Chelly J, Goizet C, Lacombe D, Pedespan JM, Echenne B, Tariverdian G, O'Rourke D, King MD, Green A, van Kogelenberg M, Van Esch H, Gecz J, Hamel BC, van Bokhoven H, de Brouwer AP. (2008) 'Structural variation in Xq28: MECP2 duplications in 1% of patients with unexplained XLMR and in 2% of male patients with severe encephalopathy'. European Journal of Human Genetics .  
Conroy J, Cochrane L, Anney RJ, Sutcliffe JS, Carthy P, Dunlop A, Mullarkey M, O'hici B, Green AJ, Ennis S, Gill M, Gallagher L. (2008) 'Fine mapping and association studies in a candidate region for autism on chromosome 2q31-q32'. American Journal of Medical Genetics .  
Bailey AJ, Baird G, Bartlett C, Battaglia A, Berney T, Betancur C, Bölte S, Bolton PF, Brian J, Bryson SE, Buxbaum JD, Cantor RM, Cook EH, Coon H, Corsello C, Cuccaro ML, Davis KL, Dawson G, de Jonge M, Devlin B, Ennis S, Estes A, Fombonne E, Freitag CM, Gallagher L, Geschwind DH, Gilbert J, Gill M, Gillberg C, Goldberg J, Green A, Green J, Guter SJ, Haines JL, Hallmayer J, Hus V, Klauck SM, Korvatska O, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lord C, Lotspeich L, Maestrini E, Mahoney W, Mantoulan C, McConachie H, McDougle CJ, McMahon WM, Miller J, Monaco AP, Munson J, Nurnberger JI Jr, Oliveira G, Papanikolaou K, Parr JR, Pericak-Vance MA, Pickles A, Piven J, Posey DJ, Poustka A, Poustka F, Renshaw K, Roberts W, Roge B, Rutter ML, Salt J, Schellenberg GD, Scherer SW, (2008) 'Genome-wide linkage analyses of quantitative and categorical autism subphenotypes'. Biological Psychiatry .  
Professor Patrick Guiry
Fitzpatrick, M. O.,Muller-Bunz, H.,Guiry, P. J. (2009) 'The Synthesis of New HetPHOX Ligands and Their Application to the Intermolecular Asymmetric Heck Reaction'. European Journal of Organic Chemistry, (12):1889-1895.  
Singh, S.,Guiry, P. J. (2009) 'A Facile Synthesis of Both Enantiomers of 6-Acetoxy-5-hexadecanolide, a Major Component of Mosquito Oviposition Attractant Pheromones'. European Journal of Organic Chemistry, (12):1896-1901.  
Guiry PJ, Singh S, (2009) 'Microwave-assisted synthesis of substituted tetrahydropyrans catalyzed by ZrCl4 and its application in the asymmetric synthesis of exo- and endo-brevicomin'. Journal of Organic Chemistry, 74 (15):5758-5761.  
Guiry PJ, Fleming WJ, Müller-Bunz H, Lillo V, Fernández E, (2009) 'Axially chiral P-N ligands for the copper catalyzed beta-borylation of alpha,beta-unsaturated esters'. Organic and Biomolecular Chemistry, 7 (12):2520-2524.  
Guiry PJ, Hargaden GC, (2009) 'Recent applications of oxazoline-containing ligands in asymmetric catalysis'. Chemical Reviews, 109 (6):2505-2550.  
Guiry PJ, Coeffard V, Müller-Bunz H, (2009) 'The synthesis of new oxazoline-containing bifunctional catalysts and their application in the addition of diethylzinc to aldehydes'. Organic and Biomolecular Chemistry, 7 (8):1723-1734.  
Guiry PJ, Shah ST, Singh S, (2009) 'A Novel, Chemoselective and Efficient Microwave-Assisted Deprotection of Silyl Ethers with Selectfluor'. Journal of Organic Chemistry .  
Fekner, T.,Muller-Bunz, H.,Guiry, P. J. (2008) 'Synthesis, Resolution, and Application of Cyclobutyl- and Adamantyl-Quinazolinap Ligands'. European Journal of Organic Chemistry, (30):5055-5066.  
Guiry PJ, Maxwell AC, Franc C, Pouchain L, Muller-Bunz H. (2008) 'Electronically varied quinazolinaps for asymmetric catalysis'. Org Biomol Chem, 20 (NA):3848-3853.  
Dr Chandralal Hewage
Malthouse JP, Howe N, Rogers L, Hewage C, (2009) 'Oxyanion and Tetrahedral Intermediate Stabilization by subtilisin: Detection of a new tetrahedral adduct'. Biochimica et biophysica acta, 1794 (8):1251-1258.  
Professor Desmond Gerard Higgins
McLoughlin P, Leonard MO, Howell K, Madden SF, Costello CM, Higgins DG, Taylor CT, (2008) 'Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung'. American journal of respiratory and critical care medicine, 9 (NA):977-983.  
Professor Suzi Jarvis
Mostaert, A.S., Giordani, C., Crockett, R., Karsten, U., Schumann, R. & Jarvis, S.P. (2009) 'Characterisation of amyloid nanostructures in the natural adhesive of unicellular subaerial algae'. The Journal of Adhesion, 85 :465-483. Available Online  
N.S. Murray, S.P. Jarvis and T. Gunnlaugsson (2009) 'Luminescent self-assembly formation on a gold surface observed by reversible ¿off-on¿ switching of Eu(III) emission'. Chemical Communications, :4959-4961.  
J.I. Kilpatrick, A. Gannepalli, J. P. Cleveland and S. P. Jarvis (2009) 'Frequency modulation atomic force microscopy in ambient environments utilizing robust feedback tuning'. Review of Scientific Instruments, 80 .  
Professor Michael Keane
Belperio JA, Weigt SS, Elashoff RM, Huang C, Ardehali A, Gregson AL, Kubak B, Fishbein MC, Saggar R, Keane MP, Saggar R, Lynch JP 3rd, Zisman DA, Ross DJ, (2009) 'Aspergillus colonization of the lung allograft is a risk factor for bronchiolitis obliterans syndrome'. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 9 (8):1903-1911.  
Keane MP, King R, Stenke E, Kelly E, McDermott S, Hickey C, Murphy K, Tubridy N, (2009) 'Recurrent malaise and oedema in a 35-year-old female'. Intensive care medicine, 35 (7):1314-1315.  
Professor Therese Kinsella
Donnellan PD, Kinsella BT (2009) 'Immature and mature species of the human Prostacyclin Receptor are ubiquitinated and targeted to the 26S proteasomal or lysosomal degradation pathways, respectively'. Journal of Molecular Signaling, 25 .  
Elizabeth C. Turner & B. Therese Kinsella. (2009) 'Transcripional Regulation of the Human Prostacyclin Receptor Gene is dependent on Sp1, Pu.1 and Oct-1 in Megakaryocytes and Endothelial Cells'. Journal of Molecular Biology, 386 :579-597.  
Professor Ulla Knaus
Bhandarkar SS, Jaconi M, Fried LE, Bonner MY et al. (2009) 'Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice'. J Clin Invest, 119 (8):2359-2365.  
Sylvia Luxen, Deborah Noack, Monika Frausto, Suzel Davanture, Bruce E. Torbett and Ulla G. Knaus (2009) 'Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells'. J Cell Sci, 122 :1238-1247.  
Mandy Lehmann, Deborah Noack, Malcolm Wood, Marta Perego, Ulla G Knaus (2009) 'Lung Epithelial Injury by B. Anthracis Lethal Toxin Is Caused by MKK-Dependent Loss of Cytoskeletal Integrity'. Plos One, 4 (3).  
Manukyan M, Nalbant P, Luxen S, Hahn K, Knaus UG (2009) 'RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kB'. J IMMUNOL, 182 (6):3522-3529.  
von Lohneysen K, Noack D, Jesaitis AJ, Dinauer MC, Knaus UG (2008) 'Mutational analysis reveals distinct features of the Nox4-p22phox complex'. J BIOL CHEM .  
Professor Gil Lee
Ajit K. Mahapatro, D. Janes, K. Jeong, and G. Lee (2009) 'Stable and reporducible electronic conduction through DNA molecular junctions'. Applied Physics Letters, 95 (083106).  
Professor Patrick Lonergan
Evans AC, McAuliffe FM, Quinn K, Lonergan P, Smith NA, (2009) 'Transient high glycaemic intake in the last trimester of pregnancy increases offspring birthweight and postnatal growth rate in sheep: a randomised control trial'. BJOG : an international journal of obstetrics and gynaecology, 116 (7):975-983.  
Evans AC, Bettegowda A, Scheetz D, Walsh S, Mossa F, Knight PG, Smith GW, Lonergan P, Ireland JJ, Zielak-Steciwko AE, Jimenez-Krassel F, Folger J, (2009) 'Variation in the ovarian reserve is linked to alterations in intrafollicular estradiol production and ovarian biomarkers of follicular differentiation and oocyte quality in cattle'. Biology of Reproduction, 80 (5):954-964.  
Crowe MA, Beltman ME, Lonergan P, Diskin MG, Roche JF, (2009) 'Effect of progesterone supplementation in the first week post conception on embryo survival in beef heifers'. Theriogenology, 71 (7):1173-1179.  
Evans AC, Ryan KE, Glister C, Lonergan P, Martin F, Knight PG, (2008) 'Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vitro and in vivo studies in cattle and sheep'. Journal of ovarian research, 1 (1).  
Dr David MacHugh
Gu J, Orr N, Park SD, Katz LM, Sulimova G, MacHugh DE, Hill EW (2009) 'A genome scan for positive selection in thoroughbred horses'. PLoS ONE, 4 (6). Available Online  
O'Gorman GM, Park SD, Hill EW, Meade KG, Coussens PM, Agaba M, Naessens J, Kemp SJ, MacHugh DE (2009) 'Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility'. BMC Genomics, 10 . Available Online  
Machugh DE, Gormley E, Park SD, Browne JA, Taraktsoglou M, O'Farrelly C, Meade KG (2009) 'Gene Expression Profiling of the Host Response to Mycobacterium bovis Infection in Cattle'. Transboundary and emerging diseases . Available Online  
Berry DP, McParland S, Kearney JF, Machugh DE, (2008) 'Inbreeding effects on postweaning production traits, conformation, and calving performance in Irish beef cattle'. Journal of Animal Science, 86 (12):3338-3347.  
Meade, K.G., Gormley, E. O¿Farrelly, C. Park, S.D., Costello, E., Keane, J., Zhao, Y., MacHugh, D.E. (2008) 'Antigen stimulation of peripheral blood mononuclear cells from Mycobacterium bovis0 infected cattle yields evidence for a novel gene expression program'. BMC Genomics, 9 . Available Online  
MacHugh DE, Meade KG, Gormley E, O'Farrelly C, Park SD, Costello E, Keane J, Zhao Y, (2008) 'Antigen stimulation of peripheral blood mononuclear cells from Mycobacterium bovis infected cattle yields evidence for a novel gene expression program'. Genomics, 9 .  
Professor Jonathan Malthouse
Malthouse JP, Howe N, Rogers L, Hewage C, (2009) 'Oxyanion and Tetrahedral Intermediate Stabilization by subtilisin: Detection of a new tetrahedral adduct'. Biochimica et biophysica acta, 1794 :1251-1258.  
Dr Gethin McBean
Godson C, Decker Y, McBean G, (2009) 'Lipoxin A4 inhibits IL-1{beta}-induced IL-8 and ICAM-1 expression in 1321N1 human astrocytoma cells'. American journal of physiology. Cell physiology, 296 (NA):C1420-C1427.  
McBean GJ, Murphy A, Vines A, (2009) 'Stimulation of EAAC1 in C6 glioma cells by store-operated calcium influx'. Biochimica et biophysica acta, 1788 :551-558.  
Dr Margaret McGee
Bannon JH, Mc Gee MM. (2009) 'Understanding the role of aneuploidy in tumorigenesis'. BIOCHEMICAL SOCIETY TRANSACTIONS, 37 ((Pt 4):):910-913.  
Bane FT, Bannon JH, Pennington SR, Campiani G, Williams DC, Zisterer DM, Mc Gee MM, (2009) 'The microtubule-targeting agents, PBOX-6 and paclitaxel, induce nuclear-cytoplasmic redistribution of the peptidyl prolyl isomerases, cyclophilin A and pin1, in malignant haematopoietic cells'. Journal of Pharmacology and Experimental Therapeutics, 329 :38-47.  
Professor Paul McLoughlin
McLoughlin P, Costello CM, Cahill E, Martin F, Gaine S, (2009) 'Role of Gremlin in the Lung: Development and Disease'. American Journal of Respiratory Cell and Molecular Biology .  
McLoughlin P, Howell K, Costello CM, Sands M, Dooley I, (2009) 'L-Arginine promotes angiogenesis in the chronically hypoxic lung: a novel mechanism ameliorating pulmonary hypertension'. American journal of physiology. Lung cellular and molecular physiology, 6 (NA):1-50.  
McLoughlin P, Leonard MO, Howell K, Madden SF, Costello CM, Higgins DG, Taylor CT, (2008) 'Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung'. American Journal of Respiratory and Critical Care Medicine, 178 (9):977-983. Available Online  
Dr Tara McMorrow
Jennings P, Aydin S, Bennett J, McBride R, Weiland C, Tuite N, Gruber LN, Perco P, Gaora PO, Ellinger-Ziegelbauer H, Ahr HJ, Kooten CV, Daha MR, Prieto P, Ryan MP, Pfaller W, McMorrow T (2009) 'Inter-laboratory comparison of human renal proximal tubule (HK-2) transcriptome alterations due to Cyclosporine A exposure and medium exhaustion'. Toxicology in Vitro, 23 (3):486-499.  
O Riordan A., Johnston O., McMorrow T., Wynne K., Maguire P., Hegarty J.E., McCormick A., Watson A.J., Cagney G., Gallagher W.M. and Ryan M.P. (2008) 'Identification of Apolipoprotein AI as a serum biomarker of chronic kidney disease in liver transplant recipients, using proteomic techniques'. Proteomics Clinical Applications, 2 (8):1338-1348.  
Nee L, O'Connell S, Nolan S, Ryan MP, McMorrow T, (2008) 'Nitric Oxide Involvement in TNF-alpha and IL-1beta-Mediated Changes in Human Mesangial Cell MMP-9 and TIMP-1'. Experimental Nephrology, 110 (2):1-1.  
Professor Walter McNicholas
Garvey, J. F.,Taylor, C. T.,McNicholas, W. T. (2009) 'Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation'. Eur Respir J, 33 (5):1195-205. Available Online  
McNicholas, W. T. (2009) 'Obstructive sleep apnea and inflammation'. Prog Cardiovasc Dis, 51 (5):392-9. Available Online  
Ryan, S.,Taylor, C. T.,McNicholas, W. T. (2009) 'Systemic inflammation: a key factor in the pathogenesis of cardiovascular complications in obstructive sleep apnoea syndrome?'. Thorax, 64 (7):631-6. Available Online  
Ryan, S.,McNicholas, W. T. (2009) 'Inflammatory cardiovascular risk markers in obstructive sleep apnoea syndrome'. Cardiovasc Hematol Agents Med Chem, 7 (1):76-81. Available Online  
Riha, R. L.,McNicholas, W. T. (2009) 'The genetic and cardiovascular aspects of obstructive sleep apnoea/hypopnoea syndrome'. Eur Respir J, 33 (2):233-6. Available Online  
Ryan, S.,Doherty, L. S.,Rock, C.,Nolan, G. M.,McNicholas, W. T. (2009) 'Effects of Salmeterol on Sleeping Oxygen Saturation in Chronic Obstructive Pulmonary Disease'. Respiration . Available Online  
de Chazal P, Heneghan C, McNicholas WT. (2009) 'Multimodal detection of sleep apnoea using electrocardiogram and oximetry signals'. Philos Transact A Math Phys Eng Sci, 367 (1887):369-389.  
Heneghan, C.,Chua, C. P.,Garvey, J. F.,de Chazal, P.,Shouldice, R.,Boyle, P.,McNicholas, W. T. (2008) 'A portable automated assessment tool for sleep apnea using a combined Holter-oximeter'. Sleep, 31 (10):1432-9. Available Online  

Ryan, S.,McNicholas, W. T. (2008) 'Intermittent hypoxia and activation of inflammatory molecular pathways in OSAS'. Arch Physiol Biochem, 114 (4):261-6. Available Online  
Harte, S.,McNicholas, W. T.,Donnelly, S. C.,Dodd, J. D. (2008) 'Honeycomb cysts in idiopathic pulmonary haemosiderosis: high-resolution CT appearances in two adults'. Br J Radiol, 81 (972):e295-8. Available Online  
Rodenstein D; Cost-B26 Action on Sleep Apnoea Syndrome (2008) 'Driving in Europe: the need of a common policy for drivers with obstructive sleep apnoea syndrome'. Journal of Sleep Research, 17 (3):281-284.  
Professor Wim Meijer
Smith, C.J., B.S. Danilowicz, W.G. Meijer (2009) 'Bacteria associated with the mucus layer of Merlangius merlangus0 (whiting) as biological tags to determine harvest location'. Canadian Journal of Fisheries and Aquatic Science, 66 :713-716.  
Vazquez-Boland, J.A., Prescott, J.F., Meijer, W.G, Leadon DP, Hines, S.A. (2009) 'Rhodococcus equi comes of age'. Equine Veterinary Journal, 41 (1):93-95.  
Dr Anika Mostaert
Mostaert, A.S., Giordani, C., Crockett, R., Karsten, U., Schumann, R. and Jarvis, S.P. (2009) 'Characterisation of amyloid nanostructures in the natural adhesive of unicellular subaerial algae'. The Journal of Adhesion, 85 :465-483. Available Online  
Hedderman, T.G., Mostaert, A.S., Shanahan, A.E. and Byrne, H.J. (2009) 'The dispersion of SWCNT bundles on interaction with p-Terphenyl'. New Carbon Materials, 24 (1):73-82. Available Online  
Fukuma, T., Mostaert, A.S., Serpell, L.C. and Jarvis, S.P. (2008) 'Revealing molecular-level surface structure of amyloid fibrils in liquid by means of frequency modulation atomic force microscopy'. Nanotechnology, 19 (38):384010-(6pp).  
Dr Evelyn Murphy
Brayden DJ, Keely S, Ryan SM, Haddleton DM, Limer A, Mantovani G, Murphy EP, Colgan SP, (2009) 'Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers'. Journal of controlled release : official journal of the Controlled Release Society, 1 (NA):35-43.  
Dr Keith J Murphy
Regan CM, Seymour CM, Foley AG, Murphy KJ, (2008) 'Intraventricular infusions of anti-NCAM PSA impair the process of consolidation of both avoidance conditioning and spatial learning paradigms in Wistar rats'. Neuroscience, 157 (4):813-820.  
Regan CM, Conboy L, Foley AG, O'Boyle NM, Lawlor M, Gallagher HC, Murphy KJ, (2008) 'Curcumin-induced degradation of PKCdelta is associated with enhanced dentate NCAM PSA expression and spatial learning in adult and aged Wistar rats'. Biochemical Pharmacology, 77 (7):1254-1265.  
Dr Jarlath Nally
Nally JE, Sayers G, Marques PX, Evans NJ, O'Grady L, Doherty ML, Carter SD, (2009) 'Identification of spirochetes associated with contagious ovine digital dermatitis'. JOURNAL OF CLINICAL MICROBIOLOGY, 4 (NA):1199-1201.  
Avril M. Monahan, John J. Callanan, and Jarlath E. Nally (2008) 'A proteomic analysis of Leptospira0 being shed in urine of chronically infected hosts'. Infection and Immunity, 76 (11):4952-4958.  
Professor Philip Newsholme
McClenaghan NH, Scullion SM, Mion B, Hewage C, Malthouse JPG, Flatt PR, Newsholme P, Brennan L (2009) 'Prolonged L-alanine exposure induces changes in metabolism, Ca 2+ handling and desensitisation of insulin secretion in clonal pancreatic beta-cells'. CLINICAL SCIENCE, 116 :341-351.  
Vinolo MA, Hatanaka E, Lambertucci RH, Newsholme P, Curi R. (2009) 'Effect of short chain fatty acids on effector mechanisms of neutrophils'. CELL BIOCHEMISTRY AND FUNCTION, 27 (1):48-55.  
Keane D. and Newsholme P. (2008) 'Saturated and unsaturated (including arachidonic acid) non-esterified fatty acid modulation of insulin secretion from pancreatic beta-cells'. BIOCHEMICAL SOCIETY TRANSACTIONS, 36 :955-958.  
Dr Jens Erik Nielsen
Nielsen JE, Søndergaard CR, Garrett AE, Carstensen T, Pollastri G, (2009) 'Structural Artifacts in Protein-Ligand X-ray Structures: Implications for the Development of Docking Scoring Functions'. Journal of medicinal chemistry, 52 (18):5674-5684.  
Lepperdinger G, Reitinger S, Müllegger J, Greiderer B, Nielsen JE, (2009) 'Designed human serum hyaluronidase 1 variant, HYAL1{Delta}L, exhibits activity up to pH 5.9'. Journal of Biological Chemistry, 284 (29):19173-19177.  
Professor Ronan O'Connell
Jones JF, Banahan M, Peirce C, Buffini M, O'Herlihy C, O'Connell PR, (2009) 'Atrophy of the sphincters of continence in an experimental model'. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, (NA).  
Jones JF, Peirce C, Healy CF, O'Herlihy C, O'Connell PR, (2009) 'Reduced somatosensory cortical activation in experimental models of neuropathic fecal incontinence'. Diseases of the colon and rectum, 8 (NA):1417-1422.  
O'Connell PR, Burke JP, Watson RW, Murphy M, Docherty NG, Coffey JC, (2009) 'Simvastatin impairs smad-3 phosphorylation and modulates transforming growth factor beta1-mediated activation of intestinal fibroblasts'. The British Journal of Surgery, 5 (NA):541-551.  
O'Connell PR, Coffey JC, Rowan F, Burke J, Dochery NG, Kirwan WO, (2009) 'Pathogenesis of and unifying hypothesis for idiopathic pouchitis'. The American journal of gastroenterology, 4 (NA):1013-1023.  
O'Connell PR, Ryan JD, Joyce MR, Pierce C, Brannigan A, (2009) 'Haematoma in a hydrocele of the canal of Nuck mimicking a Richter's hernia'. Hernia : the journal of hernias and abdominal wall surgery, (NA).  
O'Connell PR, Rowan FE, Docherty NG, Coffey JC, (2009) 'Sulphate-reducing bacteria and hydrogen sulphide in the aetiology of ulcerative colitis'. The British Journal of Surgery, 2 (NA):151-158.  
O'Riordan JM, Healy CF, McLoughlin D, Cassidy M, Brannigan AE, O'Connell PR. (2009) 'ANTIPLATELET AGENTS IN THE PERIOPERATIVE PERIOD'. Archives of Surgery, 144 (1):69-76.  
O'Connell PR, (2008) 'Stapled haemorrhoidopexy for the treatment of haemorrhoids: a systematic review Burch J, Epstein D, Baba-Akbari Sari A et al, Colorectal Disease doi: 10.1111/j.1463-1318.2008.01638.x'. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, (NA).  
Jones JF, Healy CF, O'Herlihy C, O'Brien C, O'Connell PR, (2008) 'Experimental models of neuropathic fecal incontinence: an animal model of childbirth injury to the pudendal nerve and external anal sphincter'. Diseases of the colon and rectum, 11 (NA):1619-161.  
Fakhro A, O¿Riordan JM, Lawler LP, O¿Connell PR (2008) 'CECAL VULVULUS AS A COMPLICATION OF GASTRIC BANDING'. Obesity Surgery .  
Jones JF, Peirce C, Healy CF, O'Herlihy C, O'Connell PR, (2008) 'Effect of prolonged vaginal distention and sphincter transection on physiologic function of the external anal sphincter in an animal model'. Obstetrics and gynecology, 4 (NA):943-91.  
O'Connell PR, Burke JP, Ferrante M, Dejaegher K, Watson RW, Docherty NG, De Hertogh G, Vermeire S, Rutgeerts P, D'Hoore A, Penninckx F, Geboes K, Van Assche G, (2008) 'Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohn's disease'. Inflammatory bowel diseases, (NA):1197-1204.  
O'Herlihy C, Mahony R, Behan M, O'Connell PR, (2008) 'Effect of second vaginal delivery on anal function in patients at risk of occult anal sphincter injury after first forceps delivery'. Diseases of the colon and rectum, 9 (NA):1361-1366.  
Dr Kevin O'Connor
O'Connor KE, Goff M, Nikodinovic-Runic J, (2009) 'Characterization of temperature-sensitive and lipopolysaccharide overproducing transposon mutants of Pseudomonas putida CA-3 affected in PHA accumulation'. FEMS MICROBIOL LETT, 2 (NA):297-305.  
O'Connor KE, Kenny ST, Runic JN, Kaminsky W, Woods T, Babu RP, Keely CM, Blau W, (2008) 'Up-cycling of PET (polyethylene terephthalate) to the biodegradable plastic PHA (polyhydroxyalkanoate)'. Environmental Science &Amp; Technology, 42 (20):7696-7701.  
O'Connor KE, Nikodinovic J, Kenny ST, Babu RP, Woods T, Blau WJ, (2008) 'The conversion of BTEX compounds by single and defined mixed cultures to medium-chain-length polyhydroxyalkanoate'. Applied microbiology and biotechnology, 4 (NA):665-673.  
Dr James O'Gara
Stevens, N., Greene, C.M., O'Gara, J. P. and Humphreys, H. (2009) 'Biofilm characteristics of Staphylococcus epidermidis isolates associated with device-related meningitis'. Journal of Medical Microbiology, 58 (7):855-862.  
Cotter, J.J., O'Gara, J. P. and E. Casey (2009) 'Rapid depletion of dissolved oxygen in 96 well microtitre plate Staphylococcus epidermidis biofilm assays promotes biofilm development and is influenced by inoculum cell concentration'. Biotechnology and Bioengineering, 103 (5):1042-1047.  
Glynn, A. A., S. T. O'Donnell, D. C. Molony, E. Sheehan, D. J. McCormack, and J. P. O'Gara. (2009) 'Hydrogen peroxide induced repression of icaADBC transcription and biofilm development in Staphylococcus epidermidis'. Journal of Orthopaedic Research, 27 :627-630.  
O'Neill, E., Humphreys, H., and O'Gara, J.P. (2009) 'Carriage of both the fnbA and fnbB genes and growth at 37oC promotes FnBP-mediated biofilm development in MRSA clinical isolates'. Journal of Medical Microbiology, 58 :399-402.  
Stevens, N. T., Sadovskaya, I., Jabbouri, S., Sattar, T., O'Gara, J. P., Humphreys, H. and C. M. Greene (2009) 'Staphylococcus epidermidis Polysaccharide Intercellular Adhesin induces IL-8 expression in human astrocytes via a mechanism involving TLR2'. Cellular Microbiology, 11 :421-432.  
Cotter, J.J., O'Gara, J. P., Mack, D. and E. Casey (2009) 'Oxygen-mediated regulation of biofilm development is controlled by the alternative sigma factor σB in Staphylococcus epidermidis'. Applied and Environmental Microbiology, 75 :261-264.  
Professor Stefan Oscarson
Oscarson S, Bonaccorsi F, Catelani G, (2009) 'A new route for the synthesis of Streptococcus pneumoniae 19F and 19A capsular polysaccharide fragments avoiding the beta-mannosamine glycosylation step'. Carbohydrate research, 344 (12):1442-1448.  
Andersson, Claes-Henrik; Lahmann, Martina; Oscarson, Stefan; Grennberg, Helena (2009) 'Reversible non-covalent derivatisation of carbon nanotubes with glycosides'. Soft Matter, 5 (14):2713-2716.  
J. D. M. Olsson, S. Oscarson (2009) 'Synthesis of phosphorylated Neisseria meningitidis inner core lipopolysaccharide structures'. TETRAHEDRON-ASYMMETR, 20 :879-886.  
Casadevall A, Nakouzi A, Zhang T, Oscarson S, (2009) 'The common Cryptococcus neoformans glucuronoxylomannan M2 motif elicits non-protective antibodies'. Vaccine, 27 (27):3513-3518.  
Widmalm G, Olsson JD, Landström J, Rönnols J, Oscarson S, (2009) 'Synthesis of and molecular dynamics simulations on a tetrasaccharide corresponding to the repeating unit of the capsular polysaccharide from Salmonella enteritidis'. Organic &Amp; Biomolecular Chemistry, 7 (8):1612-1618.  
Surolia A, Gupta G, Gemma E, Oscarson S, (2008) 'Defining substrate interactions with calreticulin: an isothermal titration calorimetric study'. Glycoconjugate journal, 25 (8):797-802.  
Snippe H, Safari D, Dekker HA, Joosten JA, Michalik D, de Souza AC, Adamo R, Lahmann M, Sundgren A, Oscarson S, Kamerling JP, (2008) 'Identification of the smallest structure capable of evoking opsonophagocytic antibodies against Streptococcus pneumoniae type 14'. Infection and Immunity, 76 (10):4615-4623.  
Oscarson S, Olsson JD, Eriksson L, Lahmann M, (2008) 'Investigations of glycosylation reactions with 2-N-acetyl-2N,3O-oxazolidinone-protected glucosamine donors'. Journal of Organic Chemistry, 73 (18):7181-7188.  
Mowbray SL, Covarrubias AS, Högbom M, Bergfors T, Carroll P, Mannerstedt K, Oscarson S, Parish T, Jones TA, (2008) 'Structural, biochemical, and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis'. Journal of Molecular Biology, 381 (3):622-633.  
Dr Francesca Paradisi
Conway PA, Devine K, Paradisi F (2009) 'A simple and efficient method for the synthesis of Erlenmeyer azlactones'. Tetrahedron, 65 (15):2935-2938.  
O'Reilly E, Lestini E, Baiducci D, et al. (2009) 'One-step diketopiperazine synthesis using phase transfer catalysis'. Tetrahedron Letters, 50 (15):1748-1750.  
Paradisi, F. et al. (2008) 'Engineered dehydrogenase biocatalysts for non-natural amino acids: efficient isolation of the D-enantiomer from racemic mixtures'. Organic and Biomolecular Chemistry .  
Gleeson, B. et al. (2008) '\i Novel organotin antibacterial and anticancer drugs0'. Polyhedron, 27 :3619-3624.  
Professor William Powderly
Havlir DV, Haubrich RH, Riddler SA, Dirienzo AG, Komarow L, Powderly WG, Klingman K, Garren KW, Butcher DL, Rooney JF, Haas DW, Mellors JW, (2009) 'Metabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment'. AIDS .  
Mondy K, Onen NF, Overton ET, Presti R, Blair C, Powderly WG, (2009) 'Sub-optimal CD4 recovery on long-term suppressive highly active antiretroviral therapy is associated with favourable outcome'. HIV Medicine, 10 :439-446.  
Zolopa A, Andersen J, Komarow L, Sanchez A, Sanne I, Suckow C, Hogg E, Powderly W (2009) 'Early antiretroviral therapy reduces AIDS progression/death in individuals with acute opportunistic infections: a multicenter randomized strategy trial'. PLoS ONE, 4 (5). Available Online  
Professor Prem Puri
Darlow, J. M.,Molloy, N. H.,Green, A. J.,Puri, P.,Barton, D. E. (2009) 'The increased incidence of the RET p.Gly691Ser variant in French-Canadian vesicoureteric reflux patients is not replicated by a larger study in Ireland'. Hum Mutat, 30 (5):E612-7. Available Online  
Cserni, T.,O' Donnel A,Paran, S.,Puri, P. (2009) 'Correlation of enteric NADPH-d positive cell counts with the duration of incubation period in NADPH-d histochemistry'. Pathol Oncol Res, 15 (1):103-7. Available Online  
Cserni, T.,Paran, S.,Kanyari, Z.,O'Donnell, A. M.,Kutasy, B.,Nemeth, N.,Puri, P. (2009) 'New insights into the neuromuscular anatomy of the ileocecal valve'. Anat Rec (Hoboken), 292 (2):254-61. Available Online  
O'Donnell, A. M.,Puri, P. (2009) 'Cholinergic innervation in the developing chick cloaca and colorectum'. J Pediatr Surg, 44 (2):392-4. Available Online  
Doi, T.,Sugimoto, K.,Puri, P. (2009) 'Up-regulation of COUP-TFII gene expression in the nitrofen-induced hypoplastic lung'. J Pediatr Surg, 44 (2):321-4. Available Online  
Everett, K. V.,Capon, F.,Georgoula, C.,Chioza, B. A.,Reece, A.,Jaswon, M.,Pierro, A.,Puri, P.,Gardiner, R. M.,Chung, E. M. (2008) 'Linkage of monogenic infantile hypertrophic pyloric stenosis to chromosome 16q24'. Eur J Hum Genet, 16 (9):1151-4. Available Online  
Mohanan, N.,Colhoun, E.,Puri, P. (2008) 'Renal parenchymal damage in intermediate and high grade infantile vesicoureteral reflux'. J Urol, 180 (4 Suppl):1635-8; discus. Available Online  
O' Donnell AM,Puri, P. (2008) 'RET/GDNF signalling in vagal neural crest-derived neurons of the chick embryo cloaca'. Pediatr Surg Int, 24 (11):1211-4. Available Online  
Donnell, A. M.,Doi, T.,Hollwarth, M.,Kalicinski, P.,Czauderna, P.,Puri, P. (2008) 'Deficient alpha-smooth muscle actin as a cause of functional intestinal obstruction in childhood'. Pediatr Surg Int, 24 (11):1191-5. Available Online  
Doi, T.,Puri, P.,Bannigan, J.,Thompson, J. (2008) 'Downregulation of ROCK-I and ROCK-II gene expression in the cadmium-induced ventral body wall defect chick model'. Pediatr Surg Int, 24 (12):1297-301. Available Online  
O' Donnell AM,Puri, P. (2008) 'Vagal neural crest provides inhibitory neurotransmission to the chick embryo cloaca'. Pediatr Surg Int, 24 (12):1323-6. Available Online  
Sri Paran, T.,Rolle, U.,Puri, P. (2008) 'Postnatal changes in enteric plexus axonal thickness'. Pediatr Surg Int, 24 (12):1365-7. Available Online  
Puri P, Donnell AM, Doi T, Hollwarth M, Kalicinski P, Czauderna P, (2008) 'Deficient alpha-smooth muscle actin as a cause of functional intestinal obstruction in childhood'. Pediatr Surg Int, 11 (NA):1191-1195.  
Puri P, O' Donnell AM, (2008) 'RET/GDNF signalling in vagal neural crest-derived neurons of the chick embryo cloaca'. Pediatr Surg Int, 11 (NA):1211-1214.  
Puri P, Mohanan N, Colhoun E, (2008) 'Renal parenchymal damage in intermediate and high grade infantile vesicoureteral reflux'. The Journal of urology, 4 Suppl (NA):1635-161.  
Puri P, Menezes M, Pini Prato A, Jasonni V, (2008) 'Long-term clinical outcome in patients with total colonic aganglionosis: a 31-year review'. The Journal of pediatrics, 43 (9):1696-1699.  
Professor Ciaran Regan
Regan CM, Seymour CM, Foley AG, Murphy KJ, (2008) 'Intraventricular infusions of anti-NCAM PSA impair the process of consolidation of both avoidance conditioning and spatial learning paradigms in Wistar rats'. Neuroscience, 4 (NA):813-820.  
Regan CM, Conboy L, Foley AG, O'Boyle NM, Lawlor M, Gallagher HC, Murphy KJ, (2008) 'Curcumin-induced degradation of PKCdelta is associated with enhanced dentate NCAM PSA expression and spatial learning in adult and aged Wistar rats'. BIOCHEM PHARMACOL, 77 (7):1254-1265.  
Professor Helen Roche
Roche HM, de Roos B, Rungapamestry V, Ross K, Rucklidge G, Reid M, Duncan G, Horgan G, Toomey S, Browne J, Loscher CE, Mills KH, (2009) 'Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet'. Proteomics, 9 (12):3244-3256.  
Mullen A, Loscher CE, Roche HM, (2009) 'Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages'. Journal of Nutritional Biochemistry, 8 :658-666.  
Osada J, Guillén N, Navarro MA, Arnal C, Noone E, Arbonés-Mainar JM, Acín S, Surra JC, Muniesa P, Roche HM, (2009) 'Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver'. Physiological Genomics, 37 (3):187-198.  
Lovegrove JA, Shaw DI, Tierney AC, McCarthy S, Upritchard J, Vermunt S, Gulseth HL, Drevon CA, Blaak EE, Saris WH, Karlström B, Helal O, Defoort C, Gallego R, López-Miranda J, Siedlecka D, Malczewska-Malec M, Roche HM, (2009) 'LIPGENE food-exchange model for alteration of dietary fat quantity and quality in free-living participants from eight European countries'. British Journal of Nutrition, 101 (5):750-759.  
de Wit N, Baccini M, Bachmaier EM, Biggeri A, Boekschoten MV, Bouwman FG, Brennan L, Caesar R, Cinti S, Coort SL, Crosley K, Daniel H, Drevon CA, Duthie S, Eijssen L, Elliott RM, van Erk M, Evelo C, Gibney M, Heim C, Horgan GW, Johnson IT, Kelder T, Kleemann R, Kooistra T, van Iersel MP, Mariman EC, Mayer C, McLoughlin G, Müller M, Mulholland F, van Ommen B, Polley AC, Pujos-Guillot E, Rubio-Aliaga I, Roche HM, de Roos B, Sailer M, Tonini G, Williams LM, (2008) 'The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation'. Genes & Nutrition, 3 (3-4):147-151.  
Lairon D, Szabo de Edelenyi F, Goumidi L, Bertrais S, Phillips C, Macmanus R, Roche H, Planells R, (2008) 'Prediction of the metabolic syndrome status based on dietary and genetic parameters, using Random Forest'. Genes & Nutrition, 3 (3-4):173-176.  
Daniel H, van Ommen B, Cavallieri D, Roche HM, Klein UI, (2008) 'The challenges for molecular nutrition research 4: the nutritional systems biology level'. Genes & Nutrition, 3 (3-4):107-113.  
Roche HM, Morine MJ, O'Brien C, (2008) 'Session 2: Personalised nutrition. Transcriptomic signatures that have identified key features of metabolic syndrome'. The Proceedings of the Nutrition Society, 67 (4):395-403.  
Professor Denis Shields
Moran N, Bernard E, Parthasarathi L, Cho MK, Aylward K, Raab M, Daxecker H, O'Dushlaine CT, Shields DC, Devocelle M, Keyes T, Cosgrave L, O'Neill S, Mok KH, (2009) 'Ligand switching in cell-permeable peptides: manipulation of the alpha-integrin signature motif'. Chemistry & biology, 4 (6):457-471.  
Edwards RJ, Davey NE, Shields DC, (2009) 'Masking residues using context-specific evolutionary conservation significantly improves short linear motif discovery'. Bioinformatics, 25 (4):443-450.  
Shields DC, Parthasarathi L, Casey F, Stein A, Aloy P, (2008) 'Approved Drug Mimics of Short Peptide Ligands from Protein Interaction Motifs'. Journal of Chemical Information and Modeling .  
Shields DC, Casey FP, Cagney G, Krogan NJ, (2008) 'Optimal stepwise experimental design for pairwise functional interaction studies'. Bioinformatics .  
Professor Jeremy Charles Simpson
Simpson, J.C. (2009) 'Screening the secretion machinery: High throughput imaging approaches to elucidate the secretory pathway'. Seminars in Cell and Developmental Biology, 20 :903-909.  
Martinez-Morales, J.R., Rembold, M., Greger, K., Simpson, J.C., Brown, K.E., Quiring, R., Pepperkok, R., Martin-Bermudo, M.D., Himmelbauer, H. and Wittbrodt, J. (2009) 'Ojoplano-mediated basal constriction is essential for optic cup morphogenesis'. Development, 136 (13):2165-2175.  
Dr Albert Peter Smolenski
Neumüller O, Hoffmeister M, Babica J, Prelle C, Gegenbauer K, Smolenski AP, (2009) 'Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets'. Blood, 114 (7):1396-1404.  
Dr Matthias Tacke
B. Gleeson, J. Claffey, A. Deally, M. Hogan, L. M. Menéndez Méndez, H. Müller-Bunz, S. Patil, D. Wallis, M. Tacke (2009) 'Synthesis and Cytotoxicity Studies of Fluorinated Derivatives of Vanadocene Y'. European Journal of Inorganic Chemistry, :2804-2810.  
M. Hogan, M. Tacke (2009) 'Bioorganometallic Chemistry: A Key To New Chemotherapy?'. Insights into Coordination, Bioinorganic and Applied Inorganic Chemistry, :403-412.  
B. Gleeson, J. Claffey, M. Hogan, H. Müller-Bunz, D. Wallis, M. Tacke (2009) 'Novel Benzyl-Substituted Vanadocene Anticancer Drugs'. Journal of Organometallic Chemistry, 694 :1369-1374.  
D. Wallis, J. Claffey, B. Gleeson, M. Hogan, H. Müller-Bunz, M. Tacke (2009) 'Novel Zirconocene Anticancer Drugs?'. Journal of Organometallic Chemistry, 694 :828-833.  
A. Vessières, M.-A. Plamont, C. Cabestaing, J. Claffey, S. Dieckmann, M. Hogan, H. Müller-Bunz, K. Strohfeldt, M. Tacke (2009) 'Proliferative and Antiproliferative Effects of Titanium- and Iron-Based Metallocene Anticancer Drugs'. Journal of Organometallic Chemistry, 694 :874-879.  
B. Gleeson, J. Claffey, D. Ertler, M. Hogan, H. Müller-Bunz, F. Paradisi, D. Wallis, M. Tacke (2008) 'Novel Organotin Antibacterial and Anticancer'. Polyhedron, 27 :3619-3624.  
I. Fichtner, J. Claffey, B. Gleeson, M. Hogan, D. Wallis, H. Weber, M. Tacke (2008) '\i Antitumor Activity of Oxali-Titanocene Y in Xenografted Caki-1 Tumors in Mice0'. Letters in Drug Design & Discovery, 5 :489-493.  
M. Tacke (2008) 'The Interaction of Titanocene Y with Double-Stranded DNA: A Computational Study'. Letters in Drug Design & Discovery, 5 :332-335.  
M. Hogan, J. Cotter, J. Claffey, B. Gleeson, D. Wallis, D. O¿Shea, M. Tacke (2008) '\i Synthesis and Cytotoxicity Studies of New Dimethylamino-Functionalised and Azaindole-Substituted Titanocene Anticancer Agents0'. Helvetica Chimica Acta, 91 :1787-1797.  
Professor Cormac Taylor
Prime, TA, Blaikie, FH, Evans, C, Nodtochiy, SM, James, AM, Dahm, CC, Vitturi, DA, Patel, RP, Hiley, CR, Abakumova, I, Requejo, R, Chouchani, ET, Hurd, TR, Garvey, JF, Taylor, CT, Brookes, PS, Smith, RAJ & Murphy, MP. (2009) 'A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury'. PNAS, 106 :10764-10769.  
Victor, VM, Nunez, C, D¿Ocon, P, Taylor, CT, Esplugues, JV and Moncada, S. (2009) 'Regulation of oxygen distribution in tissues by nitric oxide'. Circulation Research, 104 :1178-1183.  
O¿Hagan, KA, Cochiglia, S, Zhdanov, AV, Tambawala, MM, Cummins, EP, Monafared, M, Agbor, TA, Garvey, JF, Papkovsky, D, Taylor, CT* & Allan, BB* (2009) 'PGC-1? is coupled to HIF-1?-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells'. PNAS, 106 :2188-2193.  
McLoughlin P, Leonard MO, Howell K, Madden SF, Costello CM, Higgins DG, Taylor CT, (2008) 'Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung'. American journal of respiratory and critical care medicine, 9 (NA):977-983.  
Dr Emma C Teeling
Teeling, E.C., Boutros, R., Stokes, N. and Bekaert, M. (2009) 'UniPrime2: a web service providing easier Universal Primer design'. Nucleic Acids Research, 37 (Web Server Issue):1-13.  
Teeling, E.C. (2009) 'Hear, hear: the convergent evolution of echolocation in bats?'. Trends in Ecology and Evolution, 24 (7):351-354.  
Zhang, S., Zhao, H., Rossiter, S.J., Teeling, E.C., Li, C. and Cotton. J.A. (2009) 'The evolution of color vision in nocturnal mammals'. Proceedings of the National Academy of Sciences of the United States of America, 106 (22):8980-8985.  
Professor Dominic Walsh
Walsh DM, Shankar GM, Leissring MA, Adame A, Sun X, Spooner E, Masliah E, Selkoe DJ, Lemere CA, (2009) 'Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life'. Neurobiology of Disease, 36 (2):293-302.  
Selkoe D, Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, (2009) 'Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake'. Neuron, 62 (6):788-801.  
Walsh DM, Minogue AM, Stubbs AK, Frigerio CS, Boland B, Fadeeva JV, Tang J, Selkoe DJ, (2009) 'gamma-secretase processing of APLP1 leads to the production of a p3-like peptide that does not aggregate and is not toxic to neurons'. Brain Research, 1262 :89-99.  
Sean D. O¿Shea, Imelda M. Smith, Olive M. McCabe, Michelle M. Cronin, Dominic M. Walsh and William T. O¿Connor (2008) 'Intracerebroventricular administration of amyloid b-protein oligomers selectively increases dorsal hippocampal dialysate glutamate levels in the awake rat.0'. Sensors, 8 :7428-7437.  
Linse S, Cabaleiro-Lago C, Quinlan-Pluck F, Lynch I, Lindman S, Minogue AM, Thulin E, Walsh DM, Dawson KA, (2008) 'Inhibition of amyloid beta protein fibrillation by polymeric nanoparticles'. Journal of the American Chemical Society, 130 (46):15437-15443.  
Neng-Wei Hu, Imelda M. Smith, Dominic M. Walsh and Michael J. Rowan (2008) 'Soluble amyloid-ß peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo'. Brain, 131 :2414-2424.  
Walsh DM, Betts V, Leissring MA, Dolios G, Wang R, Selkoe DJ, (2008) 'Aggregation and catabolism of disease-associated intra-Abeta mutations: reduced proteolysis of AbetaA21G by neprilysin'. Neurobiology of Disease, 31 (3):442-450.  
Dr Xiangming Zhu
Xiangming Zhu, Richard R. Schmidt (2009) 'New Principles for Glycoside Bond Formation'. Angewandte Chemie International Edition, 48 :1900-1934.  
Ravindra T. Dere, Xiangming Zhu (2008) 'The First Synthesis of a Thioglycoside Analogue of the Immunostimulant KRN7000'. Organic Letters, 10 (20):4641-4644.  
Cristina Lucas-Lopez, Niamh Murphy, Xiangming Zhu (2008) 'Catalytic Glycosylation with Glycosyl Thioimidate Donors'. European Journal of Organic Chemistry, 2008 (26):4401-4404.  
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Conference Publications
Professor Mohamed Al-Rubeai
Boehm D., Murphy W. G. and Al-Rubeai M. (2009) The effect of cell crowdedness on ex vivo erythropoiesis of peripheral blood derived CD34+ cells Human pluripotent stem cells symposium, Dublin,  
Al-Rubeai M. (2009) Life, stress and death in the bioreactor Cell Line Development and Engineering,  
Boehm D., Murphy W. G. and Al-Rubeai M. (2009) The Influence of the microenvironment on cell expansion, maturation and viability in ex vivo erythropoiesis of peripheral blood derived CD34+ cells 19th European Society for Animal Cell Culture (ESACT-UK) Annual Meeting, Hinxton,  
Krampe, B. and Al-Rubeai, M. (2009) The Influence of the microenvironment on cell expansion, maturation and viability in ex vivo erythropoiesis of peripheral blood derived CD34+ cells 19th European Society for Animal Cell Culture (ESACT-UK) Annual Meeting, Hinxton,  
Al-Rubeai M. (2008) Cell engineering strategy to improve stability, adaptation and growth of cell lines for bioproduction IV National Congress of Bioengineering, Izmir, Turkey,  
Boehm D., Murphy W., Al-Rubeai M. (2008) Ex-vivo production of human red blood cells from peripheral blood derived CD34+ cells Stem Cells Europe,  
Krampe B. and Al-Rubeai M. (2008) Transcriptome analysis of antibody producing NS0 cells in chemostat and perfusion cultures 7th European Symposium on Biochemical Engineering Science (ESBES7),  
Professor David Brayden
Bzik, V & Brayden DJ (2009) Permeating-enhancing and cytotoxic effects of 1-phenyl piperazine in rat colonic mucosa 36th Int. Soc. Controlled Release Society, Abstract 703  
Ryan, SM, McMorrow, J., Murphy, E.P. & Brayden, D. J. (2009) Salmon calcitonin as a potential therapeutic for osteoarthritis and rheumatoid arthritis 36th Int. Soc. Controlled Release Society, Copenhagen, Abstract 450  
Wang, X & Brayden, D.J. (2009) Bone regeneration after acute injected bisphophonate and calcitonin repeated treatments in overiectomised rats Osteoporosis Conference 2009, Manchester, Supplement 4, S2  
Dr John Crean
Godson C, Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, (2008) Biochemical Society transactions Regulation and consequences of differential gene expression in diabetic kidney disease, 941 - 945  
Professor Alexander Evans
F Jimenez-Krassel, JK Folger, M Mondal, DM Scheetz, JLH Ireland, GW Smith, F Mossa, P Lonergan, ACO Evans, JJ Ireland. (2009) Evidence that the inherently high variation in ovarian reserves is positively associated with androgen and estradiol production in cattle 42nd Annual Meeting of Society for the Study of Reproduction, Pittsburgh,  
SW Walsh, JA Browne, MA Crowe, M Mihm and ACO Evans. (2009) Comparison of follicular fluid steroid concentration & mRNA levels in preovulatory follicles between heifers and lactating cows 42nd Annual Meeting of Society for the Study of Reproduction, Pittsburgh,  
L Richardson, JP Hanrahan, A Donovan, S Fair, L O'Hara, M O'Sullivan, P Lonergan, ACO Evans (2009) Sperm penetration and viscosity of cervical mucus in sheep breeds differing in pregnancy rate to cervical AI with frozen thawed semen 42nd Annual Meeting of Society for the Study of Reproduction, Pittsburgh,  
T Swangchan-Uthai, SW Walsh, S Alexander, Z Cheng, MA Crowe, ACO Evans, C Wathes. (2009) Influence of cycle stage and lactation on expression of insulin-like growth factor binding proteins (IGFBPs) in the bovine oviduct 42nd Annual Meeting of Society for the Study of Reproduction,  
F Mossa, D Kenny, F Jimenez-Krassel, GW Smith, D Berry, S Butler, T Fair, P Lonergan, JJ Ireland, ACO Evans. (2009) Undernutrition of heifers during the first trimester of pregnancy diminishes size of the ovarian reserve in female offspring 42nd Annual Meeting of Society for the Study of Reproduction, Pittsburgh,  
N Forde, P Mc Gettigan, JA Browne, B Loftus, J Roche, ACO Evans, P Lonergan, MA Crowe. (2009) Pregnancy specific endometrial gene expression at the initiation of conceptus elongation in cattle 42nd Annual Meeting of Society for the Study of Reproduction, Pittsburgh,  
F Mossa, D Kenny, F Jimenez-Krassel, GW Smith, D Berry, ST Butler, T Fair, P Lonergan, JJ Ireland, ACO Evans. (2009) Effect of undernutrition of heifers during the first trimester of pregnancy on blood pressure in female offspring Workshop of the Gemini-cost action working group 1 Experimental models, Lansk, Poland,  
Dr Jana Haase
Malynn S, Grudzinska J. Campos-Torres A, Haase J. (2008) Stress and cytokine regulated neuronal membrane glycoprotein M6a interacts with and regulates the serotonin transporter (SERT) First Annual Symposium of SFB35 Transmembrane Transporters in Health and Disease,  
Professor Therese Kinsella
T. Kinsella. (2008) Expression and intracellular signalling by the TPa and TPb isoforms of the human thromboxane A2 receptor Biochemical Society (IAS) Gold Medal Lecture, Presented that the Genome Instability and Cancer, Biochemical Society (IAS) Focused Meeting, National University of Ireland, Galway, Ireland,  
Katarina Wikström, David J. Kavanagh, Helen M. Reid & B. Therese Kinsella. (2008) Differential Regulation of RhoA-mediated Signaling by the TPa and TPb isoforms of the human Thromboxane A2 Receptor Conway Institute Annual Festival of Research,  
Helen M. Reid, Martina B. O¿Keeffe, Karol English & B. Therese Kinsella. (2008) Role of Rab5 in Agonist-Induced Internalization of the human Prostacyclin Receptor Moderated poster, presented at Conway Institute Annual Festival of Research,  
Professor Paul McLoughlin
Costello CM, Howell K, Doherty S, Martin F, Belperio J, Keane M, Gaine, S, McLoughlin, P (2009) Potential selective role for CXCR7/CXCL12 signalling in the lung in response to hypoxic stress Physiological Society Annual General Meeting,  
Michelle Sands, Katherine Howell, Christine Costello, Paul McLoughlin (2009) VEGF Family Members can Inhibit Angiogenesis in the Hypoxic Lung Physiological Society Annual General Meeting,  
Cahill E, Costello CM, Howell K, Leonard MO, Southwood M, Morrell NW, McLoughlin P (2009) Hypoxic Upregulation of the BMP Antagonist Gremlin Blocks BMP Signalling in Pulmonary Endothelial Cells Physiological Society Annual Meeting,  
Cahill E, Costello CM, Howell K, Leonard MO, Southwood M, Morrell NW, McLoughlin P (2009) Hypoxic Upregulation of the BMP Antagonist Gremlin Blocks BMP Signalling in Pulmonary Endothelial Cells European Respiratory Society Lung Biology Meeting,  
Costello, CM, Howell K, Brennan D, Doherty S, Martin, F, Gaine, S, McLoughlin, P (2009) Potential selective role for CXCR7/CXCL12 signalling in the lung in response to hypoxic stress European Respiratory Society Lung Biology Meeting,  
Dr Tara McMorrow
Radford R., Ryan M.P., McMorrow T. (2008) Development of Renal Cell Culture Models of Carcinogenesis within the E.U. CarcinoGENOMICS Project: Analysis of Epithelial Mesenchymal Transition (EMT) Induction American Society of Nephrology,  
Martin N., Ryan G.E., McMorrow T., Ryan M.P. (2008) Molecular Mechanisms of Immunosuppressant-Induced Alteration of Barrier Function in Renal Proximal Tubular Cells American Society of Nephrology,  
Bennett J., Ryan M.P., McMorrow T. (2008) Molecular Mechanisms of Immunosuppressive Agents in Human Renal Proximal Tubular Cells American Society of Nephrology,  
Professor Philip Newsholme
N. Mullooly and P. Newsholme (2009) Effects of a glucokinase activator on glucolipotoxix and cytokine-induced beta cell dysfunction and cell integrity Physiology 2009 Oral Communications,  
M. Salvucci, Z. Neufeld and P. Newsholme (2009) Developing a mathematical model of insulin release from pancreatic beta cells: The importance of glutamate Physiology 2009 Poster Communications,  
R.E. Sumayao and P. Newsholme (2009) Effect of cstine dimethylester lysosomal loading on the viability of LLC-PK1 cells Physiology 2009 Poster Communications,  
M. Krause, P.I. Homem de Bittencourt Jr and P. Newsholme (2009) The effect of IL-6 on insulin secretion, nitric oxide release, redox status and signal transduction in a clonal pancreatic beta cell line Physiology 2009 Oral Communications,  
M. Farrelly, C. Murphy and P. Newsholme (2009) Effects of Interleukin-6 on glucagons secretion and viability of the pancreatic alpha cell line (alpha-TC1-9) Physiology 2009 Poster Communications,  
Kiely A and Newsholme P (2008) TLR agonist induced changes in BRIN-BD11 clonal beta cell metabolism, signal transduction and insulin secretion The European Association for the Study of Diabetes 44th Annual meeting Rome, Rome, Italy, S263 - S264  
Mullooly N, Newsholme P, Smith D (2008) Assessment of the AstraZeneca glucokinase activator GKA50 on pancreatic beta cell function and viability in the clonal beta cell line BRIN-BD11 The European Association for the Study of Diabetes 44th Annual meeting Rome, Rome Italy, S201 - S201  
Kiely AM, Newsholme P (2008) TLR agonist induced changes in BRIN-BD11 clonal beta cell metabolism, signal transduction and insulin secretion The European Assocition for the Study of Diabetes 44th Annual meeting Rome, Rome Italy, S263 - S264  
Dr Jens Erik Nielsen
Predrag Kukić, Damien Farrell, Chresten Søndergaard, Una Bjarnadottir, John Bradley, Gianluca Pollastri , Jens Erik Nielsen (2009) Improving the analysis of NMR spectra tracking pH-induced conformational changes: Removing artefacts of the electric field on the NMR chemical shift Celebrate the 50th Anniversary of the Determination of the Structure of Myoglobin. VIII European Symposium of The Protein Society Zurich, Switzerland, June 14-18, 2009,  
Fergal O¿Meara, Chresten R. Søndergaard, Michael A. Johnston, Jens Erik Nielsen (2009) Using an Alanine Scan of Hen Egg White Lysozyme (HEWL) to Validate PEAT-SA Celebrate the 50th Anniversary of the Determination of the Structure of Myoglobin. VIII European Symposium of The Protein Society Zurich, Switzerland, June 14-18, 2009,  
Professor William Powderly
NS Chew, EJ Cotter, PP Doran, WG Powderly (2008) High HIV viral load inhibits osteoblast function and signalling . In: Journal of the International AIDS Society 11(Suppl 1):O33 eds. Ninth International Congress on Drug Therapy in HIV Infection, Available Online  
NS Chew, S McConkey, J Lambert, G Sheehan WG Powderly (2008) Traditional risk factors do not predict osteoporosis in HIV patients . In: BioMed Central eds. Ninth International Congress on Drug Therapy in HIV Infection, Available Online  
Dr Tadhg Ó'Cróinín
N. Corcionivoschi, A. Alemka, M. Clyne, T. O¿Croinin, B. Bourke (2009) Host Derived Reactive Oxygen Species Modulate Bacterial Tyrosine Phosphorylation Pathway to Attenuate CPS Production in Campylobacter jejuni 81-176 during Infection of Human Epithelial Cells American Society of Microbiology : Annual General Meeting,  
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Puri P, Gillick J, Mortell A, Dawrant M, Giles S, Bannigan J, (2008) 'The Adriamycin rat/mouse model and its importance to the paediatric surgeon'. Pediatr Surg Int, 1 (NA):113-118.  
Puri P, Mortell A, Amjad B, Breatnach F, Devaney D, (2007) 'Penile malignant peripheral nerve sheath tumour (schwannoma) in a three-year-old child without evidence of neurofibromatosis'. European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 6 (NA):428-430.  
Puri P, Rolle U, Piaseczna-Piotrowska A, (2007) 'Interstitial cells of Cajal in the normal gut and in intestinal motility disorders of childhood'. Pediatr Surg Int, 12 (NA):1139-1152.  
Kelly, H.,Molony, C. M.,Darlow, J. M.,Pirker, M. E.,Yoneda, A.,Green, A. J.,Puri, P.,Barton, D. E. (2007) 'A genome-wide scan for genes involved in primary vesicoureteric reflux'. J Med Genet, 44 (11):710-7.  
Menezes, M. N.,Puri, P. (2007) 'The role of endoscopic treatment in the management of grade v primary vesicoureteral reflux'. Eur Urol, 52 (5):1505-9.  
Barton DE, Kelly H, Molony CM, Darlow JM, Pirker ME, Yoneda A, Green AJ, Puri P, (2007) 'A genome-wide scan for genes involved in primary vesicoureteric reflux'. JOURNAL OF MEDICAL GENETICS, 11 (NA):710-717.  
Murphy, F. L.,Mazlan, T. A.,Tarheen, F.,Corbally, M. T.,Puri, P. (2007) 'Gastroschisis and exomphalos in Ireland 1998-2004. Does antenatal diagnosis impact on outcome?'. Pediatr Surg Int, 23 (11):1059-1063.  
Menezes, M.,Mohanan, N.,Haroun, J.,Colhoun, E.,Puri, P. (2007) 'New contralateral vesicoureteral reflux after endoscopic correction of unilateral reflux--is routine contralateral injection indicated at initial treatment?'. J Urol, 178 (4 Pt 2):1711-3.  
Puri, P.,Mohanan, N.,Menezes, M.,Colhoun, E. (2007) 'Endoscopic treatment of moderate and high grade vesicoureteral reflux in infants using dextranomer/hyaluronic acid'. J Urol, 178 (4 Pt 2):1714-6; discus.  
Chertin, B.,Mohanan, N.,Farkas, A.,Puri, P. (2007) 'Endoscopic treatment of vesicoureteral reflux associated with ureterocele'. J Urol, 178 (4 Pt 2):1594-7.  
Puri P, Dawrant MJ, Giles S, Bannigan J, (2007) 'Adriamycin produces a reproducible teratogenic model of vertebral, anal, cardiovascular, tracheal, esophageal, renal, and limb anomalies in the mouse'. J Pediatr Surg, 10 (NA):1652-1658.  
Sato, H.,Murphy, P.,Giles, S.,Bannigan, J.,Takayasu, H.,Puri, P. (2007) 'Visualizing expression patterns of Shh and Foxf1 genes in the foregut and lung buds by optical projection tomography'. Pediatr Surg Int .  
Puri P, Dawrant MJ, Giles S, Bannigan J, (2007) 'Adriamycin produces a reproducible teratogenic model of vertebral, anal, cardiovascular, tracheal, esophageal, renal, and limb anomalies in the mouse'. J Pediatr Surg, 10 (NA):1652-1658.  
O' Donnell AM,Puri, P. (2007) 'Deficiency of purinergic P2Y receptors in aganglionic intestine in Hirschsprung's disease'. Pediatr Surg Int .  
Kuroda, S.,Solari, V.,Puri, P. (2007) 'Association of transforming growth factor-beta1 gene polymorphism with familial vesicoureteral reflux'. J Urol, 178 (4 Pt 2):1650-3.  
Rolle, U.,Piaseczna-Piotrowska, A.,Puri, P. (2007) 'Interstitial cells of Cajal in the normal gut and in intestinal motility disorders of childhood'. Pediatr Surg Int .  
Dawrant, M. J.,Giles, S.,Bannigan, J.,Puri, P. (2007) 'Adriamycin produces a reproducible teratogenic model of vertebral, anal, cardiovascular, tracheal, esophageal, renal, and limb anomalies in the mouse'. J Pediatr Surg, 42 (10):1652-8.  
Cserni, T.,Paran, S.,Puri, P. (2007) 'New hypothesis on the pathogenesis of ileocecal intussusception'. J Pediatr Surg, 42 (9):1515-9.  
Puri P, Cserni T, Paran S, (2007) 'New hypothesis on the pathogenesis of ileocecal intussusception'. J Pediatr Surg, 9 (NA):1515-1519.  
Puri P, Cserni T, Paran S, (2007) 'New hypothesis on the pathogenesis of ileocecal intussusception'. J Pediatr Surg, 9 (NA):1515-1519.  
Professor Ciaran Regan
ter Horst, J. P. F., Loscher, J. S., Pickering, M., Regan, C. M., Murphy, K. J., (2008) 'Learning-associated regulation of polysialylated neural cell adhesion molecule expression in the rat prefrontal cortex is region-, cell type- and paradigm-specific'. European Journal of Neuroscience, 28 (3):419-427.  
Shankar, G. M., Li, S. M., Mehta, T. H., Garcia-Munoz, A., Shepardson, N. E., Smith, I., Brett, F. M., Farrell, M. A., Rowan, M. J., Lemere, C. A., Regan, C. M., Walsh, D. M., Sabatini, B. L., Selkoe, D. J., (2008) 'Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory'. Nature Medicine, 14 (8):837-842.  
Foley AG, Hirst WD, Gallagher HC, Barry C, Hagan JJ, Upton N, Hunter AJ, Walsh FS, Regan CM (2008) 'The selective 5-HT(6) receptor antagonists SB-271046 and SB-399885 potentiate NCAM PSA immunolabeling of dentate granule cells, but not neurogenesis, in the hippocampal formation of mature Wistar rats'. Neuropharmacology, 54 (8):1166-1174.  
Dr Wilhelm Risse
Nikitin, K., Mueller-Bunz, H., Ortin, Y., Risse, W., McGlinchey, M. J., (2008) 'Twin triptycyl spinning tops: A simple case of molecular gearing with dynamic C2 symmetry'. European Journal of Organic Chemistry, (18):3079-3084.  
Curran, K., Risse, W., Boggioni, L., Tritto, I., (2008) 'Addition polymers of strained cyclic olefins - Transition metal catalysed polymerisations of the cyclobutene derivative bicyclo[3.2.0]hept-6-ene'. Macromolecular Chemistry and Physics, 209 (7):707-714.  
Professor Helen Roche
Phillips CP, Tierney AC & Roche HM. (2008) 'Gene-Nutrient Interactions in the Metabolic Syndrome'. Journal of Nutrigenetics & Nutrigenomics, 1 :136-151.  
Reynolds CM, Loscher CE, Moloney AE, Roche HM (2008) 'Cis-9, trans-11-conjugated linoleic acid but not its precursor trans-vaccenic acid attenuate inflammatory markers in the human colonic epithelial cell line Caco-2'. BRITISH JOURNAL OF NUTRITION .  
Roche HM, Mullen A, Moloney F, Nugent AP, Doyle L, Cashman KD, (2007) 'Conjugated linoleic acid supplementation reduces peripheral blood mononuclear cell interleukin-2 production in healthy middle-aged males'. J Nutr Biochem, 10 (NA):658-666.  
Professor Pauline Rudd
Rudd PM, Storr SJ, Royle L, Chapman CJ, Hamid UM, Robertson JF, Murray A, Dwek RA, (2008) 'The O-linked glycosylation of secretory/shed MUC1 from an advanced breast cancer patient's serum'. Glycobiology, 18 (6):456-462.  
Dwek RA, Royle L, Campbell MP, Radcliffe CM, White DM, Harvey DJ, Abrahams JL, Kim YG, Henry GW, Shadick NA, Weinblatt ME, Lee DM, Rudd PM, (2008) 'HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software'. Analytical Biochemistry, 376 (1):1-12.  
Dwek RA, Harvey DJ, Royle L, Radcliffe CM, Rudd PM, (2008) 'Structural and quantitative analysis of N-linked glycans by matrix-assisted laser desorption ionization and negative ion nanospray mass spectrometry'. Analytical Biochemistry, 376 (1):44-60.  
Carrington SD, Royle L, Matthews E, Corfield A, Berry M, Rudd PM, Dwek RA, (2008) 'Glycan structures of ocular surface mucins in man, rabbit and dog display species differences'. Glycoconjugate journal .  
Rudd PM, Campbell MP, Royle L, Radcliffe CM, Dwek RA, (2008) 'GlycoBase and autoGU: tools for HPLC-based glycan analysis'. Bioinformatics, 24 (9):1214-1216.  
Rudd PM, Harvey DJ, Crispin M, Scanlan C, Singer BB, Lucka L, Chang VT, Radcliffe CM, Thobhani S, Yuen CT, (2008) 'Differentiation between isomeric triantennary N-linked glycans by negative ion tandem mass spectrometry and confirmation of glycans containing galactose attached to the bisecting (beta1-4-GlcNAc) residue in N-glycans from IgG'. Rapid communications in mass spectrometry : RCM, 22 (7):1047-1052.  
Bardor M, Séveno M, Cabrera G, Triguero A, Burel C, Leprince J, Rihouey C, Vézina LP, D'Aoust MA, Rudd PM, Royle L, Dwek RA, Harvey DJ, Lerouge P, Cremata JA, (2008) 'Plant N-glycan profiling of minute amounts of material'. Analytical Biochemistry .  
Kim BG, Kim YG, Shin DS, Yang YH, Gil GC, Park CG, Mimura Y, Cooper DK, Rudd PM, Dwek RA, Lee YS, (2008) 'High-throughput screening of glycan-binding proteins using miniature pig kidney N-glycan-immobilized beads'. Chemistry & biology, 15 (3):215-223.  
Stevenson FK, McCann KJ, Ottensmeier CH, Callard A, Radcliffe CM, Harvey DJ, Dwek RA, Rudd PM, Sutton BJ, Hobby P, (2008) 'Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma'. Molecular immunology, 45 (6):1567-1572.  
Gordon S, Miller JL, deWet BJ, Martinez-Pomares L, Radcliffe CM, Dwek RA, Rudd PM, (2008) 'The mannose receptor mediates dengue virus infection of macrophages'. PLoS pathogens, 4 (2).  
Cremata JA, Montesino R, Toledo JR, Sánchez O, Sánchez A, Harvey DJ, Royle L, Dwek RA, Rudd PM, Gerwig GJ, Kamerling JP, (2008) 'Monosialylated biantennary N-glycoforms containing GalNAc-GlcNAc antennae predominate when human EPO is expressed in goat milk'. Archives of biochemistry and biophysics, 470 (2):163-175.  
Rudd PM, Brooks SA, Carter TM, Royle L, Harvey DJ, Fry SA, Kinch C, Dwek RA, (2008) 'Altered glycosylation of proteins in cancer: what is the potential for new anti-tumour strategies'. Cancer, 8 (1):2-21.  
Rudd PM, Saldova R, Royle L, Radcliffe CM, Abd Hamid UM, Evans R, Arnold JN, Banks RE, Hutson R, Harvey DJ, Antrobus R, Petrescu SM, Dwek RA, (2007) 'Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG'. Glycobiology, 17 (12):1344-1356.  
Dwek RA, Scanlan CN, Ritchie GE, Baruah K, Crispin M, Harvey DJ, Singer BB, Lucka L, Wormald MR, Wentworth P Jr, Zitzmann N, Rudd PM, Burton DR, (2007) 'Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody'. Journal of Molecular Biology, 372 (1):16-22.  
Rudd PM, Domann PJ, Pardos-Pardos AC, Fernandes DL, Spencer DI, Radcliffe CM, Royle L, Dwek RA, (2007) 'Separation-based glycoprofiling approaches using fluorescent labels'. Proteomics, 7 Suppl 1 :70-76.  
Professor Michael P Ryan
Slattery, C., Ryan, M. P., McMorro, T., (2008) 'E2A proteins: Regulators of cell phenotype in normal physiology and disease'. International Journal of Biochemistry & Cell Biology, 40 (8):1431-1436.  
Slattery, C., Ryan, M. P., McMorrow, T., (2008) 'Protein kinase C beta overexpression induces fibrotic effects in human proximal tubular epithelial cells'. International Journal of Biochemistry & Cell Biology, 40 (10):2218-2229.  
Professor Denis Shields
Ryan, A. W., O'Brien, E., Shields, D., McManus, R., (2008) 'Lack of association between NFKBIL1/LTA polymorphisms and hypertension, myocardial infarct, unstable angina and stable angina in a large Irish population sample'. Atherosclerosis, 197 (1):465-466.  
Tregouet DA, Grisoni ML, Proust C, Alanne M, Desuremain M, Salomaa V, Kuulasmaa K, Cambien F, Nicaud V, Stegmayr B, Virtamo J, Shields D, Kee F, Tiret L, Evans A, (2008) 'Haplotypic analysis of tag SNPs of the interleukin-18 gene in relation to cardiovascular disease events: the MORGAM Project'. European Journal of Human Genetics .  
Shields DC, Casey FP, Davey NE, Baran I, Varekova RS, (2008) 'Web server to identify similarity of amino acid motifs to compounds (SAAMCO)'. Journal of Chemical Information and Modeling, 48 (7):1524-1529.  
Shields DC, Edwards RJ, Davey NE, (2008) 'CompariMotif: quick and easy comparisons of sequence motifs'. Bioinformatics, 10 (NA):1307-1309.  
Edwards, R. J., Davey, N. E., Shields, D. C., (2008) 'CompariMotif: quick and easy comparisons of sequence motifs'. Bioinformatics, 24 (10):1307-1309.  
O'Dushlaine, C. T., Shields, D. C., (2008) 'Marked variation in predicted and observed variability of tandem repeat loci across the human genome'. BMC Genomics, 9 .  
Shields DC, O'Dushlaine CT, (2008) 'Marked variation in predicted and observed variability of tandem repeat loci across the human genome'. Genomics, 9 .  
Shields DC, O'Halloran AM, Patterson CC, Horan P, Maree A, Curtin R, Stanton A, McKeown PP, (2008) 'Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2)'. Journal of thrombosis and thrombolysis .  
Iohom, G.,Ni Chonghaile, M.,O'Brien J, K.,Cunningham, A. J.,Fitzgerald, D. F.,Shields, D. C. (2007) 'An investigation of potential genetic determinants of propofol requirements and recovery from anaesthesia'. Eur J Anaesthesiol, 24 (11):912-9.  
Professor Jeremy Charles Simpson
Schallus, T., Jaeck, C., Feher, K., Palma, A.S., Liu, Y., Simpson, J.C., Stier, G., Gibson, T.J., Feizi, T., Pieler, T. and Muhle-Goll, C. (2008) 'Malectin - a novel carbohydrate-binding protein in the endoplasmic reticulum with a potential role in the N-glycosylation pathway'. Molecular Biology of the Cell, 19 (8):3404-3414. Available Online  
Dejgaard, S.Y., Murshid, A., Erman, A., Lodge, R., Ly, T.B.N., Pepperkok, R., Simpson, J.C. and Presley, J.F. (2008) 'Comprehensive analysis of Golgi-localized Ras-family proteins finds new proteins involved in ER/Golgi trafficking'. Journal of Cell Science, 121 :2768-2781. Available Online  
Fladeby, C., Gupta, S.N., Barois, N., Lorenzo, P.I., Simpson, J.C., Saatcioglu, F. and Bakke, O. (2008) 'Human PARM-1 is a novel mucin-like, androgen-regulated gene exhibiting proliferative effects in prostate cancer cells'. International Journal of Cancer, 122 :1229-1235.  
Lin, C.C., Tsai, Y.S., Lin, Y.S., Chiu, T.Y., Hsiung, C.C., Lee, M.I., Simpson, J.C. and Hsu, C.N. (2007) 'Boosting multiclass learning with repeating codes and weak detectors for protein subcellular localization'. Bioinformatics, 23 :3374-3381.  
Dr Albert Peter Smolenski
de Oliveira SK, Smolenski A, (2008) 'Phosphodiesterases link the aryl hydrocarbon receptor complex to cyclic nucleotide signaling'. Biochemical Pharmacology .  
Hoffmeister M, Riha P, Neumüller O, Danielewski O, Schultess J, Smolenski AP, (2008) 'Cyclic nucleotide-dependent protein kinases inhibit binding of 14-3-3 to the GTPase-activating protein Rap1GAP2 in platelets'. Journal of Biological Chemistry, 283 (4):2297-2306.  
Professor Torres Sweeney
Krogenæs Anette K, Taubøll Erik, Stien Audun, Oskam Irma C, Lyche Jan L, Dahl Ellen, Thomassen Ragnar F, Sweeney Torres and Ropstad Erik. (2008) 'Valproate (VPA) affects reproductive endocrine function, testis diameter and some semen parameters in non-epileptic adolescent male'. Theriogenology, 70 :15-26.  
Bahar B, Monaghan F, Moloney A, Olaf, McHugh D and Sweeney T. (2008) 'Variations of RNA stability in post-mortem bovine skeletal muscle, liver and subcutaneous adipose tissues'. BMC Molecular Biology, 8 :108-114.  
Sweeney T and Hanrahan J.P. (2008) 'The evidence of associations between prion protein genotype and production, reproduction and health traits in sheep'. Veterinary Research, 39 (4).  
Sayers G., Good B., Hanrahan J. P., O Donovan J., Mulcahy G., Sweeney T. (2008) 'Breed differences in mucosal and systemic antibody response to nematode infection in sheep: an important role for IgE?'. Parasitology, 135 :71-80.  
Negredo, C., Monks, E, Sweeney T. (2007) 'A novel real-time ultrasonic method for prion protein detection using plasminogen as a capture molecule'. BMC Biotechnology, 7 :43-49.  
Lenahan, M. S. O'Brien, K. Kinsella, T. Sweeney, and J.J. Sheridan (2007) 'Prevalence and molecular characterisation of Escherichia coli O157:H7 on Irish lamb carcasses, fleece and in faeces samples'. Journal of Applied Microbiology, 103 (6):2401-2409.  
Sayers G., Good B., Hanrahan J. P., O Donovan J., Mulcahy G., Sweeney T. (2007) 'Breed differences in mucosal and systemic antibody response to nematode infection in sheep: an important role for IgE?'. Parasitology, :1-10.  
Dr Matthias Tacke
Strohfeldt, K., Tacke, M., (2008) 'Bioorganometallic fulvene-derived titanocene anti-cancer drugs'. Chemical Society Reviews, 37 (6):1174-1187.  
Pampillon, C., Claffey, J., Strohfeldt, K., Tacke, M., (2008) 'Synthesis and cytotoxicity studies of new dimethylamino-functionalised and aryl-substituted titanocene anti-cancer agents'. European Journal of Medicinal Chemistry, 43 (1):122-128.  
Pampillon, C., Claffey, J., Hogan, M., Tacke, M., (2008) 'Novel achiral titanocene anti-cancer drugs synthesised from bis-N,N-dimethylamino fulvene and lithiated heterocyclic compounds'. Biometals, 21 (2):197-204.  
Weber, H., Claffey, J., Hogan, M., Pampillon, C., Tacke, M., (2008) 'Analyses of Titanocenes in the spheroid-based cellular angiogenesis assay'. Toxicology in Vitro, 22 (2):531-534.  
Dowling, C. M., Claffey, J., Cuffe, S., Fichtner, I., Pampillon, C., Sweeney, N. J., Strohfeldt, K., Watson, R. W. G., Tacke, M., (2008) 'Antitumor activity of Titanocene Y in xenografted PC3 tumors in mice'. Letters in Drug Design & Discovery, 5 (2):141-144.  
Hogan, M., Claffey, J., Pampillon, C., Tacke, M., (2008) 'Synthesis and cytotoxicity studies of new morpholino-functionalised and N-heteroaryl-substituted titanocene anticancer drugs'. Medicinal Chemistry, 4 (2):91-99.  
M. Tacke (2008) 'The Interaction of Titanocene Y with Double-Stranded DNA: A Computational Study'. Letters in Drug Design & Discovery, 5 :332-335.  
J. Claffey, B. Gleeson, M. Hogan, H. Müller-Bunz, D. Wallis, M. Tacke (2008) 'Fluorinated Derivatives of Titanocene Y: Synthesis and Cytotoxicity Studies'. European Journal of Inorganic Chemistry, :4074-4082.  
J. Claffey, M. Hogan, H. Müller-Bunz, C. Pampillón, M. Tacke (2008) 'Oxali-Titanocene Y: A Potent Anticancer Drug'. Chemmedchem, 3 :729-731.  
Claffey, J., Hogan, M., Muller-Bunz, H., Pampillon, C., Tacke, M., (2008) 'Synthesis and cytotoxicity studies of methoxy benzyl substituted titanocenes'. Journal of Organometallic Chemistry, 693 (3):526-536.  
M. Hogan, J. Claffey, E. Fitzpatrick, T. Hickey, C. Pampillon, M. Tacke (2008) 'Synthesis and Cytotoxicity Studies of Titanocene C Analogues'. Metal-Based Drugs .  
Strohfeldt, K., Müller-Bunz, H., Pampillón, C., Tacke, M. (2007) 'Proliferative and Antiproliferative Effects in Substituted Titanocene Anticancer Drugs'. Transition Metal Chemistry, 32 (7):971-980.  
T. Hickey, J. Claffey, E. Fitzpatrick, M. Hogan, C. Pampillón, M. Tacke (2007) 'Dimethylamino-Functionalised and N-Heteroaryl-Substituted Titanocene Anticancer Drugs: Synthesis and Cytotoxicity Studies'. Investigational New Drugs, 25 (5):425-433.  
Professor Cormac Taylor
Leonard MO, Howell K, Madden SF, Costello CM, Higgins DG, Taylor CT, McLoughlin P (2008) 'Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung'. American Journal of Respiratory and Critical Care Medicine .  
Taylor, C. T., , (2008) 'Mitochondria, oxygen sensing, and the regulation of HIF-2 alpha. Focus on "Induction of HIF-2 alpha is dependent on mitochondrial O-2 consumption in an O-2-sensitive adrenomedullary chromaffin cell line"'. American Journal of Physiology-Cell Physiology, 294 (6):1300-1302.  
Agbor, T. A., Taylor, C. T., (2008) 'SUMO, hypoxia and the regulation of metabolism'. Biochemical Society Transactions, 36 :445-448.  
Cummins, E. P., Seeballuck, F., Keely, S. J., Mangan, N. E., Callanan, J. J., Fallon, P. G., Taylor, C. T., (2008) 'The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis'. Gastroenterology, 134 (1):156-165.  
Taylor, C. T., , (2008) 'Mitochondria and cellular oxygen sensing in the HIF pathway'. Biochemical Journal, 409 :19-26.  
Taylor CT, Pouyssegur J. (2007) 'Oxygen, hypoxia, and stress'. Annals of the New York Academy of Science, 1113 :87-94.  
Dr Emma C Teeling
Bekaert, M. and Teeling, E.C. (2008) 'UniPrime: a workflow-based platform for improved universal primer design'. Nucleic Acids Research, 36 (10).  
Springer, M.S., Meredith, R.W., Eizirik, E., Teeling, E. and Murphy, W.J. (2008) 'Morphology and placental mammal phylogeny'. Systematic Biology, 57 (3):499-503.  
S. J. Puechmaille, P. Piyapan, M. Yokubol, K. Mie Mie, P. J. Bates, C. Satasook, T. Nwe, S. Si. Hla Bu, I. Mackie & E. C. Teeling. (2008) 'Characterization and multiplex genotyping of sixteen polymorphic microsatellite loci in the endangered bumblebee-bat, Craseonycteris thonglongyai (Chiroptera: Craseonycteridae)'. Conservation Genetics .  
Dr Edward Timoshenko
Bellesia, G., Fedorov, M. V., Timoshenko, E. G., (2008) 'Structural transitions in model beta-sheet tapes'. Journal of Chemical Physics, 128 (19).  
Elli, S., Raffaini, G., Ganazzoji, F., Timoshenko, E. G., Kuznetsov, Y. A., (2008) 'Surface adsorption of comb polymers by Monte Carlo simulations'. Polymer, 49 (6):1716-1724.  
Professor Dominic Walsh
Shankar, G. M., Li, S. M., Mehta, T. H., Garcia-Munoz, A., Shepardson, N. E., Smith, I., Brett, F. M., Farrell, M. A., Rowan, M. J., Lemere, C. A., Regan, C. M., Walsh, D. M., Sabatini, B. L., Selkoe, D. J., (2008) 'Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory'. Nature, 14 (8):837-842.  
Irvine, G. B., El-Agnaf, O. M., Shankar, G. M., Walsh, D. M., (2008) 'Protein aggregation in the brain: The molecular basis for Alzheimer's and Parkinson's diseases'. Molecular Medicine, 14 (7-8):451-464.  
Frigerio, C. S., Kukar, T., Osenkowski, P., Wolfe, M. S., Golde, T., Engel, P. C., Walsh, D. M., (2008) 'Selective modulation of the gamma cleavage of Alzheimer's disease amyloid precursor proteins'. Immunology, 197 (2):165-165.  
Welzel, A. T., Smith, I. M., Herron, C., Selkoe, D. J., Walsh, D. M., (2008) 'Purification of distinct assembly forms of cell-derived Alzheimer amyloid-beta protein'. Immunology, 197 (2):164-164.  
Professor Bill Watson
Byrne, J. C., Downes, M. R., O'Donoghue, N., Fitzpatrick, J. M., Dunn, M. J., Watson, R. W. G., (2008) 'Fasting status as a consideration for human serum collection and preparation prior to depletion and analysis'. Electrophoresis, 29 (14):3055-3059.  
Cuffe, S., Dowling, C., Gill, C., Tacke, M., Fitzpatrick, J. M., Carty, M. P., Watson, R. W. G., (2008) 'Novel titanocene analogues induce apoptosis in prostate cancer epithelial cells by initiating a DNA damage response'. Ejc Supplements, 6 (9):29-29.  
Dowling, C. M., Cuffe, S., Gill, C., Tacke, M., Fitzpatrick, J. M., Watson, R. W. G., (2008) 'Effects of docetaxel and novel titanocene analogues on cell death in prostate cancer following downregulation of Id-1 and the IAPS'. European Urology Supplements, 7 (3):276-276.  
D'Arcy, F., Foley, R., Perry, A., Marignol, L., Lawler, M., Gaffney, E., Watson, R. G. W., Fitzpatrick, J. M., Lynch, T. H., (2008) 'No evidence of XMRV in irish prostate cancer patients with the R462q mutation'. European Urology Supplements, 7 (3):271-271.  
Quinlan, M. R., Docherty, N. G., Watson, R. W. G., Fitzpatrick, J. M., (2008) 'Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction'. American Journal of Physiology-Renal Physiology, 295 (1):1-11.  
Dowling, C. M., Claffey, J., Cuffe, S., Fichtner, I., Pampillon, C., Sweeney, N. J., Strohfeldt, K., Watson, R. W. G., Tacke, M., (2008) 'Antitumor activity of Titanocene Y in xenografted PC3 tumors in mice'. Letters in Drug Design & Discovery, 5 (2):141-144.  
O'Connell PR, Burke JP, Ferrante M, Dejaegher K, Watson RW, Docherty NG, De Hertogh G, Vermeire S, Rutgeerts P, D'Hoore A, Penninckx F, Geboes K, Van Assche G, (2008) 'Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohn's disease'. Inflammatory bowel diseases, (NA).  
Fitzpatrick JM, Quinlan MR, Docherty NG, Watson RW, (2008) 'Exploring Mechanisms Involved in Renal Tubular Sensing of Mechanical Stretch following Ureteric Obstruction'. American journal of physiology. Renal physiology, (NA).  
Molloy, E. J., O'Neill, A. J., Grantham-Sloan, J. J., Webb, D. W., Watson, R. W. G., (2008) 'Maternal and neonatal lipopolysaccharide and Fas responses are altered by antenatal risk factors for sepsis'. Clinical and Experimental Immunology, 151 (2):244-250.  
Quinlan, M. R., Watson, R. W. G., Docherty, N. G., Fitzpatrick, J. M., (2008) 'Establishment of an in vitro model of mechanical stretch-induced renal tubular cell apoptosis'. BJU International, 101 :41-41.  
Watson RW, Gill C, Walsh SE, Morrissey C, Fitzpatrick JM, (2007) 'Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms'. Prostate, 15 (NA):1641-1653.  
Watson RW, Molloy EJ, O'Neill AJ, Grantham-Sloan JJ, Sheridan-Pereira M, Fitzpatrick JM, Webb DW, (2007) 'Neonatal encephalopathy is associated with altered perinatal systemic neutrophil apoptosis'. American journal of perinatology, 9 (NA):525-530.  
Professor Matthias Sebastian Wilm
Yokoyama, H.,Gruss, O. J.,Rybina, S.,Caudron, M.,Schelder, M.,Wilm, M.,Mattaj, I. W.,Karsenti, E. (2008) 'Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate'. Journal of Cell Biology, 180 (5):867-875. Available Online  
Kitao, S.,Segref, A.,Kast, J.,Wilm, M.,Mattaj, I. W.,Ohno, M. (2008) 'A compartmentalized phosphorylation/dephosphorylation system that regulates U snRNA export from the nucleus'. Molecular and Cellular Biology, 28 (1):487-497. Available Online  
Thoma, C.,Fraterman, S.,Gentzel, M.,Wilm, M.,Hentze, M. W. (2008) 'Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail'. Rna-a Publication of the Rna Society, 14 (8):1579-1589. Available Online  
Nekrasov, M.,Klymenko, T.,Fraterman, S.,Papp, B.,Oktaba, K.,Kocher, T.,Cohen, A.,Stunnenberg, H. G.,Wilm, M.,Muller, J. (2007) 'Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes'. Embo Journal, 26 (18):4078-4088. Available Online  

Fraterman, S.,Zeiger, U.,Khurana, T. S.,Rubinstein, N. A.,Wilm, M. (2007) 'Combination of peptide OFFGEL fractionation and label-free quantitation facilitated proteomics profiling of extraocular muscle'. Proteomics, 7 (18):3404-3416. Available Online  
Dr Xiangming Zhu
Dere, R. T., Wang, Y. X., Zhu, X. M., (2008) 'A direct and stereospecific approach to the synthesis of alpha-glycosyl thiols'. Organic and Biomolecular Chemistry, 6 (12):2061-2063.  
Wang, X. X., Li, Z. F., Zhu, X. M., Mao, H., Zou, X. F., Kong, L. C., Li, X. S., (2008) 'Features and applications of reactions of alpha,beta-unsaturated N-acylbenzotriazoles with amino compounds'. Tetrahedron, 64 (27):6510-6521.  
Dr Tadhg Ó'Cróinín
O Croinin T and Dorman C.J. (2007) 'Expression of the Fis protein is sustained in late-exponential- and stationary-phase cultures of Salmonella enterica serovar Typhimurium grown in the absence of aeration'. MOLECULAR MICROBIOLOGY, 66 (1):237-251.  
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Other Journals
Dr John Andrew Baugh
Byrne JD, Baugh JA (2008) 'The significance of nanoparticles in particle-induced pulmonary fibrosis' McGill Journal of Medicine, 11 (1):43-50.  
Professor Alexander Evans
Evans, ACO, Mc Loughlin, N (2008) 'Infertility in Cattle:investigating problems and solutions' Public Service Review:Science and Technology, 1 .  
Evans, ACO (2008) 'A New Skills Cultivation: Agriculture is the knowledge hungry industry upon which Irleand's future depends' Public Service Review: Science and Technology, 1 .  
Professor Declan Gerard Gilheany
Gilheany, DG (2008) 'Control and Exploitation of Phosphine Oxidation: The Taming of a Chemical Enfant Terrible' Irish Chemical News .  
Dr Francesca Paradisi
Giacomini, D., Galletti, P. and Paradisi, F. (2008) ' A further step in the environmentally friendly synthesis of Profens' Innovations in Pharmaceutical Technology .  
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Conference Publications
Professor Mohamed Al-Rubeai
Al-Rubeai M. (2008) In vitro expansion of chondroprogenitor cells in 2D and 3D culture XIIth BELACT meeting,  
Boehm D., Murphy W., Al-Rubeai M. (2008) Ex-vivo production of red blood cells from peripheral blood derived CD34+ cells Cell Culture Engineering XI,  
Al-Rubeai M., Sandhu K., Naciri M. (2008) Multiparametric flow cytometry for process monitoring and prediction of virus and protein expression Cell Culture Engineering XI,  
Krampe B. and Al-Rubeai M. (2008) Transcriptional profiling of NS0-GS and NS0-Bcl-2 cells producing antibody at different steady states in chemostat culture Cell Culture Engineering XI,  
Al-Rubeai M. (2008) Cell engineering strategy to improve stability, adaptation and growth of cell lines BioProcess International Conference,  
Al-Rubeai M (2008) Suppression of apoptosis Cell Line Development and Engineering,  
Al-Rubeai M (2007) Cell line development and cell engineering strategies for the production of biopharmaceuticals from mammalian cells 2nd Asian Biomanufacturing Conference. Kuala Lumpur, Malaysia,  
Al-Rubeai M. (2007) Cell engineering of apoptosis Optimizing Cell Culture Development, CHI's Third Annual Meeting, Boston USA,  
Professor Alan Baird
Gallagher, T.K., Baird, A.W. and Winter, D.C. (2007) Altered human small bowel contractility in obesity American College of Surgeons,  
Dr Orina Belton
Belton O, McClelland S, Gawaz M, Kennerknecht E, Konrad CS, Sauer S, Schuerzinger K, Massberg S, Fitzgerald DJ, (2008) Atherosclerosis Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse,  
Professor David Brayden
Fletcher, N.F., Bexiga, M., Brayden, D. J., Brankin, B., Willett, B. J., Hosie, M. J., Jacque, J. M. & Callanan, J. J. (2008) Cell migration through the blood-brain barrier in FIV virus infection is significantly influenced by the pre-existence of virus and TNF-a within the CNS: studies using an in vitro feline BBB model J.  Immunology, 197: p. 161, Abstract 3,  
Maher, S., Wang, X, Bzik, V, McClean, S. & Brayden, D. J. (2008) Increased intestinal permeability induced by the anti-microbial peptide, melittin: in vivo and ex vivo studies Transactions of the 35th Int. Soc. Controlled Release Society, Abstract 912,  
Wang, X. & Brayden, DJ (2008) Improved absorption of salmon calcitonin from rat intestine in vivo with sodium caprate and a mucolytic, n-acetyl cysteine Transactions of the 35th Int. Soc. Controlled Release Society,  
Ryan, S., Wang, X., Mantovani, G, Haddleton, D. M. & Brayden, D.J. (2008) Enhanced intestinal delivery and stability both in vivo and in vitro of site-specific PEGylation of salmon calcitonin to different molecular sizes of POLYPEG® Transactions of the 35th Int. Soc. Controlled Release Society, Abstract 918,  
Wang, X, Tambuwala, M., & Brayden, D. J. (2008) Investigation of the absorption-enhancing effects of ethanol in rats Transactions of the 35th Int. Soc. Controlled Release Society,  
Bzik, V & Brayden DJ (2008) Comparison of three in vitro intestinal diffusion systems Transactions of the 35th Int. Soc. Controlled Release Society, New York,  
Rawlinson, LB & Brayden DJ (2008) A methacrylate polymer is bactericidal to Gram-positive and Gram-negative bacteria Society for General Microbiology,  
Haddleton, D. M., Mantovani, G. & Brayden, D. J. (2007) Synthetic glycopolymers and protein bioconjugates from living radical polymerization 235th American Chemical Society meeting,  
Dr Lorraine Brennan
Kandil, S., Brennan, L., McBean, G., (2008) Journal of Neuroimmunology Differential effects of two gliotoxins on glutathione content in rat C6 glioma cells, 169 - 169  
Professor Sean Callanan
Fletcher, N.F., Brayden, D.J., Brankin, B., WIllett, B.J., Hosie, M.J. and Callanan, J.J. (2007) Cell migration through the blood brain barrier in feline immunodeficiency virus infection is significantly influenced by the pre-existence of virus and TNF alpha within the CNS: studies using an in vitro felin BBB model 7th Annual UCD Conway Festival of Research,  
Fletcher, N.F., Brayden, D., Brankin, B., Willett, B., Hosie, M. and Callanan, J.J. (2007) Migration of feline immunodeficiency virus infected lymphocytes across an invitro feline blood brain barrier model is promoted by the basolateral presence of FIV and TNF 25th Annual metting of European Society of Veterinary Pathology,  
Dr Eoin Casey
Eoin Casey, Eoin Syron, John Shanahan, Michael Semmens (2008) Comparative economic analysis of full scale MABR configurations North American Membrane Research Conference, University of Massachusetts, Amherst, USA,  
Safari. A., Karac, A., Walter, M., Casey, E, Ivankovic, A (2008) A two-phase flow model of biofilm detachment 31st Annual Meeting of The Adhesion Society, Austin, TX. USA,  
M. Barrett, E. Casey, B. Glennon (2007) The Impact Of Mixing Times Scales And Process Parameters On The Optimisation And Scale Up Of Anti-Solvent Addition Crystallizations AIChE Annual meeting, Salt Lake City, USA,  
Professor Alexander Evans
Jimenez-Krassel, F; Folger, JK; Smith, GW; Lonergan, P; Evans, ACO, Ireland, JJ (2008) Evidence that the diminished production of progesterone during estrous cycles of cattle with low antral follicle count during follicular waves is repeatable and not caused by alterations in size of the corpus luteum Annual American Society Animal Science ADSA-ASAS meeting, Indiana, USA,  
Mossa, F; Hildebrandt, TT; Mihm, M; Kenny, D; Butler, ST; Fair, T; Lonergan, P; Evans, ACO (2008) Undernutrition during the first trmester of pregnancy does not influence fetal growth, but may affect the developmentofthe circulatory system in cattle Summer workshop of the International Society for Developmental Origins of Adult Health and Disease (DOHaD), Nottingham, UK, 7  
Smyth, N; McAuliffe, Quinn, K; Lonergan, P (2008) Feeding high glycaemic meals in the last trimester of pregnancy in ewes on lamb birth weight and postnatal growth rate Summer workshop of the International Society for Developmental Origins of Adult Health and Disease (DOHaD), Nottingham, UK, 9  
Mossa, F; Jimenez-Krassel, F; Berry, DP; Butler, S; Folger, J; Smith, GW; Lonergan, P; Ireland, JJ; Evans, ACO (2008) Alterations in FSH secretion and pituitary responsiveness to follicular fluid after ovarectomy of dairy cowswith high versus low number of antral follicles 16th International Congress on Animal Reproduction, Budapest, Hungary, 55  
Baker, PJ; Fleming, LM; Mossa, F; Lonergan, P; Evans, ACO; Mihm, M (2008) Decreased mRNA expression of dominance marker genes in preovulatory compared to newly selected dominant follicles in cattle 41st Annual Meeting of the Society for the Study of Reproduction, Hawaii, USA, 194 - 195  
Folger, J; Jimenez-Krassel, A; Bettagowda, G; Smith, G; Mossa, F; Lonergan, P; Evans, ACO, Ireland, J (2008) Evidence that numbers of mRNA transcripts for estrogen receptor alpha and beta are greater in cumulus cells and oocytes from cattle with a diminished ovarian reserve 41st Annual Meeting of the Society for the Study of Reproduction, Hawaii, USA, 87 - 88  
Forde, N; Carter, F; Fair, T; Crowe, M; Evans, ACO; Spencer, T; Bazer, F; O'Gaora, P; Mc Bride, R; Boland, M; Lonergan, P; Roche, J (2008) Effect of pregnancy and progesterone on gene expression in the uterine endometrium of cattle 41st Annual Meeting of the Society for the Study of Reproduction, Hawaii, USA, 67 - 68  
O'Hara, L; Hanrahan, JP; Richardson, L; Donovan, A; Evans, ACO; Lonergan, P (2008) The effect of diluent type and temperature on sperm motility and viability Agricultural Research Forum, Tullamore, Ireland,  
Richardson, L; Hanrahan, JP; Fair, T; O'Hara, L; Donovan, A; Lonergan, P; Evans, ACO (2008) Differences in the number of sperm penetrating cervical mucus from Belclare and Suffolk ewes Agricultural Research Forum, Tullamore, Ireland,  
Everts, RE; Sommers, A; Green, CA; Oliveira, R; Rodriguez-Zas, S; Sung, L-Y; Du, F; Evans, ACO; Boland, M; Fair, T; Lonergan, P; Renard, JP; Yang, X; Tian, X; Lewin, HA , (2007) Major differences in gene expression profiles revealed in day-25 trophoblast but not embryonic discs collected from cattle clones Second International Meeting on Mammalian Embryogenomics, Paris, France, 114  
Tian, X; Smith, SL; Everts, RE; Lonergan, P; Du, F; Sung, L-Y, Zhang, S; Yang, L; Curchoe, C; Xue, F, Sommers, A; Green, CA; Oliveira, R; Rodriguez-Zas, S; Evans, ACO; Boland, M; Fair, T, Lewin, HA; Yang, X (2007) Analyses of somatic cell nuclear reprogramming by the candidate and global gene expression approaches Second International Meeting on Mammalian Embryogenomics, 40  
Lonergan, P; Carter, F; Evans, A; Fair, T (2007) Comparative aspects of oocyte quality Proceedings of the Annual Meeting of the European Society for Domestic Animal Reproduction (ESDAR), Celle, Germany, 62  
Dr Trudee Fair
Grace O¿Gorman, Shirley A. Ellis, Pat Lonergan, Trudee Fair (2008) MHC-I gene expression in pre-implantation embryonic development in cattle American Society of Reproductive Immunology,  
Professor Brian Glennon
M. Barrett, E. Casey, B.Glennon (2007) The impact of mixing times scales and process parameters on the optimisation and scale up of anti-solvent addition crystallisations AIChE Annual Meeting, Salt Lake City, USA,  
Dr Jana Haase
Corbett D, Campos-Torres A, Haase J (2008) THE EFFECTS OF PRO-INFLAMMATORY CYTOKINES ON THE SEROTONIN TRANSPORTER AND INTERACTING PROTEINS IN A NEURONAL CELL LINE Neuroscience Ireland Conference, Galway,  
Dr Patricia Mary Kieran
Hennessy E., Hernández R., Kieran P.M.& McLoughlin H. (2008) Translating Teaching & Learning Across Disciplines in a Modular System Universitas 21 Conference: Does Teaching & Learning Translate?,  
Kieran, P.M. (2008) Introducing Problem-Based Learning to the Chemical Engineering Curriculum International Symposium in Engineering Education: Student-Centred Learning in Small Groups,  
Professor Donal MacElroy
M. McCann, R. Amsarani, M. Rahman, D. A. Mooney, D. P. Dowling and J. M. D. MacElroy (2008) Controlling the Architecture of Micro-porous SiOx and TiOx Coatings for High Temperature CO2/Air Separations The 10th International Conference on Inorganic Membranes (ICIMs), Tokyo, Japan,  
R. Amsarani, M. Rahman, D. A. Mooney, J. M. D. MacElroy and D. P. Dowling (2008) The effect of process parameters on the microstructure and thermal stability of siloxane films deposited by plasma jet system 14th International Conference on Solid Films and Surfaces, Trinity College Dublin, Ireland,  
R. Amsarani, M. Rahman, D. A. Mooney, J. M. D. MacElroy and D. P. Dowling (2007) Influence of thermal treatment on the properties of atmospheric plasma deposited SiOx coatings Technological Plasma Workshop, Belfast, N. Ireland,  
Ramamoorthy, A., R., Rahman, M., Mooney, D.A., MacElroy, J.M.D., Dowling, D.P. (2007) Experimental studies of atmospheric plasma deposited siloxane coatings SFI Science Summit 2007, CityWest, Dublin,  
Moloney, J., McDermott, T.C., Mooney, D.A., MacElroy, J.M.D. (2007) Molecular modelling of the creation of novel, ultra-thin, nano-porous layers and supported membranes using chemical vapor deposition AIChE National Annual Meeting, Salt Lake City, Utah, U.S.A,  
Landowski, M., Deshmukh, S., Mooney, D.A., MacElroy, J.M.D. (2007) Modelling the Drug Release in pH-Sensitive Hydrogels Based on Maa-Co-Hema AIChE National Annual Meeting, Salt Lake City, Utah, U.S.A,  
Moloney, J., McDermott, T.C., Mooney, D.A., MacElroy, J.M.D. (2007) Studies into the Preparation of Model Microporous Silica and Molecular Simulation of Ultra-thin Oxide Layer Deposition on Porous Substrates Conference on Computational Physics CCP2007, Brussels, Belgium,  
Deshmukh, S.A., Landowski, M., McDermott, T.C., Mooney, D.A., MacElroy, J.M.D. (2007) Molecular Simulation of Poly (N-isopropyl acrylamide) Hydrogel crosslinked by Glyoxal bis (diallyl acetal): observation of the lower-Critical-solution- temperature Conference on Computational Physics CCP2007, Brussels, Belgium,  
Akter, T., McDermott, T.C., MacElroy, J.M.D., Mooney, D.A. (2007) Modeling of thin silica layers via kinetic Monte Carlo (KMC) of TEOS (tetraethoxysilane) deposition onto nonporous substrates Conference on Computational Physics CCP2007, Brussels, Belgium,  
Dr Patricia Maguire
Atzei, P., Maguire, P. B., Kennedy, B. N., Moynagh, P. N., (2008) Journal of Neuroimmunology Cactin, a novel regulator of TLR signalling pathways, 162 - 162  
Professor Paul McLoughlin
Nichol A, O'Croinin D, Naughton F, Boylan J, McLoughlin P (2008) Buffered Hypercapnia worsens E coli induced Lung Injury in vivo American Thoracic Society International Conference,  
M. Sands, K. Howell, P. McLoughlin (2008) Pulmonary Hypertension; Stereological Quantification of Intra-Acinar Vessel Length by Lumen Diameter Distribution American Thoracic Society International Conference,  
Adamali HI, Baugh J, Fingerle-Rowson G, McLoughlin P, Donnelly SC (2008) Enzymatic actvity of macrophage inhibitory factor (MIF) regulates growth of pseudomonas aeruginosa (Pa): implications for therapeutic interventions in cystic fibrosis American Thoracic Society International Conference,  
K Howell, C Costello, M Sands, P McLoughlin (2008) Hypoxia-induced angiogenesis in the lung is nitric oxide dependent American Thoracic Society International Conference,  
CM Costello, E Cahill, K Howell, P McLoughlin (2008) Bone morphogenetic protein signalling pathway in chronic hypoxic lung disease Keystone Conference,  
MO Leonard, K Howell, CT Taylor, P McLoughlin. (2008) Hypoxic activation of CREB as a mediator of transcriptional alteration within the mouse lung Keystone Conference,  
Alistair Nichol, Finola Naughton, Donall O Croinin, John Boylan, Paul McLoughlin (2007) Buffered hypercapnia in acute lung injury Australia New Zealand Intensive Care Society Annual Scientific Meeting,  
Alistair Nichol, Finola Naughton, Donall O Croinin, John Boylan, Paul McLoughlin (2007) Hypercapnic acidosis attenuates the neutrophil inflammatory response Australia New Zealand Intensive Care Society Annual Scientific Meeting,  
Dr Tara McMorrow
Bennett, J., Ryan, M.P. and McMorrow, T. (2007) Diiferential effects of Immunosuppressive agents in human renal proximal tubular cells . In: J.Am. Soc. Nephrol eds. American Society of Nephrology, 400A  
Feighery, R., Ryan, M.P. and McMorrow, T. (2007) Proteomic Approaches to Immune-Mediated Epithelial Mesenchymal Transition (EMT) in Renal Disease . In: J. Am. Soc. Nephrol eds. American Society of Nephrology, 373A  
Professor Wim Meijer
Finn, C.E., X. Chen & W.G. Meijer. (2007) 160th Meeting of the Society for General Microbiology P MI 34 Protein networks of Rhodococcus equi,  
Miranda-CasoLuengo, R. and W.G. Meijer. (2007) 160th Meeting of the Society for General Microbiology, Manchester. p CCS 09 Iron acquisition by Rhodococcus equi,  
Dr Cormac Declan Murphy
BR Clark, S Tennant, JH Gill, E Lacey, RJ Capon and CD Murphy (2008) Pyrrolylpolyenes from fungi: biosynthesis and analogue production . In: Leandros Skaltsounis, Prokopios Magiatis eds. 7th Joint Meeting of GA, AFERP, ASP, PSE and SIF, Athens, Greece,  
Dr Evelyn Murphy
O'Kane, M., Markham, T., McEvoy, A. N., Fearon, U., Veale, D. J., FitzGerald, O., Kirby, B., Murphy, E. P., (2008) Journal of Investigative Dermatology Increased expression of the orphan nuclear receptor NURR1 in psoriasis and modulation following TNF-alpha inhibition, 300 - 310  
Anquetin, G., Rawe, S. L., McMahon, K., Murphy, E. P., Murphy, P. V., (2008) Chemistry-a European Journal Synthesis of novel migrastatin and Dorrigocin A analogues from D-glucal, 1592 - 1600  
Zocco, D., Murphy, E. P., (2008) Journal of Neuroimmunology Histamine modulates the expression of corticotrophin-releasing-hormone receptor type I in human inflammatory arthritis, 171 - 171  
McMorrow, J. P., Murphy, E. P., (2008) Journal of Neuroimmunology Transcriptional repression of thrombospondin-1 gene expression by NR4A2 in inflammatory joint disease, 172 - 172  
Dr Kathy O'Boyle
Downey C, O¿Boyle K.M. (2007) Effects of MDMA and caffeine on renal cells and drug metabolising enzymes British Pharmacological Society, Available Online  
Nolan, B., O¿Boyle K.M. (2007) The effects of caffeine on adenosine and dopamine receptor density in rat striatum British Pharmacological Society , Available Online  
Professor Colm O'Brien
Cotter TG, O'Driscoll C, O'Connor J, O'Brien CJ, (2008) Journal of neurochemistry Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo, 524 - 536  
Sarfarazi M, Aragon-Martin JA, Ritch R, Liebmann J, O'Brien C, Blaaow K, Mercieca F, Spiteri A, Cobb CJ, Damji KF, Tarkkanen A, Rezaie T, Child AH, (2008) Molecular vision Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma, 533 - 541  
O'Brien C, Cryan LM, Paraoan L, Hiscott P, Damato BE, Grierson I, Gray D, Farrell M, Doherty GA, Fitzgerald DJ, (2008) Current eye research Expression of COX-2 and prognostic outcome in uveal melanoma, 177 - 184  
Dr Matthias Tacke
Dowling, C. M., Cuffe, S., Gill, C., Tacke, M., Fitzpatrick, J. M., Watson, R. W. G., (2008) European Urology Supplements Effects of docetaxel and novel titanocene analogues on cell death in prostate cancer following downregulation of Id-1 and the IAPS, 276 - 276  
Cuffe, S., Dowling, C., Gill, C., Tacke, M., Fitzpatrick, J. M., Carty, M. P., Watson, R. W. G., (2008) Ejc Supplements Novel titanocene analogues induce apoptosis in prostate cancer epithelial cells by initiating a DNA damage response, 29 - 29  
Professor Dominic Walsh
Kukar, T. L., Ladd, T. B., Bann, M. A., Fraering, P. C., Narlawar, R., Maharvi, G. M., Healy, B., Chapman, R., Welzel, A. T., Price, R. W., Moore, B., Rangachari, V., Cusack, B., Eriksen, J., Jansen-West, K., Verbeeck, C., Yager, D., Eckman, C., Ye, W. J., Sagi, S., Cottrell, B. A., Torpey, J., Rosenberry, T. L., Fauq, A., Wolfe, M. S., Schmidt, B., Walsh, D. M., Koo, E. H., Golde, T. E., (2008) Nature Substrate-targeting gamma-secretase modulators, 925 - 62  
Klyubin, I., Betts, V., Welzel, A. T., Blennow, K., Zetterberg, H., Wallin, A., Lemere, C. A., Cullen, W. K., Peng, Y., Wisniewski, T., Selkoe, D. J., Anwyl, R., Walsh, D. M., Rowan, M. J., (2008) Journal of Neuroscience Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: Prevention by systemic passive immunization, 4231 - 4237  
Martin F, Walsh DW, Roxburgh SA, McGettigan P, Berthier CC, Higgins DG, Kretzler M, Cohen CD, Mezzano S, Brazil DP, (2008) Biochimica et biophysica acta Co-regulation of Gremlin and Notch signalling in diabetic nephropathy, 10 - 21  
Martin F, Walsh DW, Roxburgh SA, McGettigan P, Berthier CC, Higgins DG, Kretzler M, Cohen CD, Mezzano S, Brazil DP, (2008) Biochimica et biophysica acta Co-regulation of Gremlin and Notch signalling in diabetic nephropathy, 10 - 21  
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