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UCD Biomolecular & Biomedical Science

'Carpe Diem'. Image by Mrs Monica de Gaetano.

'Carpe Diem'. Image by Mrs Monica de Gaetano.

UCD School of Biomolecular & Biomedical Science - Research Publications 2010/11

Below is the list of research publications for the UCD School of Biomolecular & Biomedical Science in the academic year 2010/11




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Book Chapters
Professor William Gallagher
Collins, B. C., Lau, T. Y. K., Pennington, S. R., and Gallagher, W. M. (2011) 'Differential proteomics incorporating iTRAQ labelling and multi-dimensional separations' In: Jean-Charles Gautier (eds). Methods in Molecular Biology - Drug Safety Evaluation. N/A: Humana Press. Available Online  
Lau, T. Y. K., Collins, B. C., Stone, P., Tang, N., Gallagher, W. M., and Pennington, S. R. (2011) 'Absolute quantification of toxicological biomarkers via multiple reaction monitoring' In: Gautier, J.-C (eds). Methods in Molecular Medicine - Drug Safety Evaluation. New York: Humana Press. Available Online  
Cooney, H. C. M. and Gallagher, W. M. (2011) 'Fibulins and their role in the ECM' In: Margareta M. Mueller and Norbert E. Fusenig (eds). Tumour-Associated Fibroblasts and Their Matrix: Tumor Stroma. Unknown: Spinger Science+Business Media B. V.  
Professor Wim Meijer
Prescott, J.F., W.G. Meijer, J.A. Vazquez-Boland (2010) 'Rhodococcus' In: C.L. Gyles, J.F. Prescott, J.G. Songer, C.O. Thoen (eds). Pathogenesis of bacterial infections of animals. Ames, IA: Wiley-Blackwell Publishing.  
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Peer Reviewed Journals
Professor Steffen Backert
Zhou, P,Hussain, SK,Liles, MR,Arias, CR,Backert, S,Kieninger, J,Oyarzabal, OA (2011) 'A simplified and cost-effective enrichment protocol for the isolation of Campylobacter spp. from retail broiler meat without microaerobic incubation'. BMC microbiology, 11 .  
Backert, S,Clyne, M (2011) 'Pathogenesis of Helicobacter pylori Infection'. Helicobacter, 16 :19-25.  
Oelkers, JM,Vinzenz, M,Nemethova, M,Jacob, S,Lai, FPL,Block, J,Szczodrak, M,Kerkhoff, E,Backert, S,Schluter, K,Stradal, TEB,Small, JV,Koestler, SA,Rottner, K (2011) 'Microtubules as Platforms for Assaying Actin Polymerization In Vivo'. PLoS ONE, 6 .  
Tegtmeyer, N,Wittelsberger, R,Hartig, R,Wessler, S,Martinez-Quiles, N,Backert, S (2011) 'Serine Phosphorylation of Cortactin Controls Focal Adhesion Kinase Activity and Cell Scattering Induced by Helicobacter pylori'. Cell, 9 :520-531.  
Dr Oliver Blacque
Williams CL, Li C, Kida K, Inglis PN, Mohan S, Semenec L, Bialas NJ, Stupay RM, Chen N, Blacque OE*, Yoder BK*, Leroux MR* *co-corresponding (2011) 'MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis'. Journal of Cell Biology, 192 (6):1023-1041.  
Kaplan OI, Molla-Herman A, Cevik S, Ghossoub R, Kida K, Kimura Y, Jenkins P, Martens JR, Setou M, Benmerah A, Blacque OE. (2010) 'AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport'. Journal of Cell Science, 123 :3966-3977.  
Jensen VL, Bialas NJ, Bishop-Hurley SL, Molday LL, Kida K, Nguyen PA, Blacque OE, Molday RS, Leroux MR, Riddle DL (2010) 'Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25'. PLoS Genetics, 6 (11).  
Dr Barry Boland
Boland B, Smith DA, Mooney D, Jung SS, Walsh DM, Platt FM (2010) 'Macroautophagy is not directly involved in the metabolism of amyloid precursor protein'. Journal of Biological Chemistry, 285 (48):37415-37426.  
Professor Geraldine Butler
Sai S, Holland LM, McGee CF, Lynch DB, Butler G (2011) 'Evolution of Mating within the Candida parapsilosis Species Group'. Eukaryotic Cell, 10 (4):578-587.  
Silva AP, Miranda IM, Guida A, Synnott J, Rocha R, Silva R, Amorim A, Pina-Vaz C, Butler G, Rodrigues AG. (2011) 'Transcriptional Profiling of Azole-Resistant Candida parapsilosis Strains'. Antimicrobial Agents and Chemotherapy, 55 :3546-3556.  
Dr Patrick Caffrey
Naseem Khan, Bernard Rawlings, Patrick Caffrey (2011) 'A labile point in mutant amphotericin polyketide synthases'. Biotechnology Letters, 33 :1121-1126.  
Dr Gerard Cagney
Ryan C, Greene D, Guenole A, van Attikum H, Krogan NJ, Cunningham P, Cagney G (2011) 'Improved functional overview of protein complexes using inferred epistatic relationships'. BMC systems biology, 5 (80). Available Online  
Agbor TA, Cheong A, Comerford KM, Scholz CC, Bruning U, Clarke A, Cummins EP, Cagney G, Taylor CT (2010) 'Small ubiquitin-related modifier (SUMO)-1 protein modification promotes glycolysis in Hypoxia'. Journal of Biological Chemistry .  
Zheng J, Benschop JJ, Shales M, Kemmeren P, Greenblatt J, Cagney G, Holstege F, Li H, Krogan NJ (2010) 'Epistatic relationships reveal the functional organization of yeast transcription factors'. Molecular systems biology, 6 .  
Dr John Crean
Smith, J. Meehan, M., Crean J. and McCann A (2011) 'Alpha T-catenin (CTNNA3); A gene in the hand is worth two in the nest'. Cellular and Molecular Life Sciences, 68 (15):2493-2498.  
Kavanagh DH, Savage DA, Patterson CC, McKnight AJ, Crean JK (2011) 'Association Analysis of Canonical Wnt Signalling Genes in Diabetic Nephropathy'. PLoS ONE, 6 (8).  
C. O'Donovan, Fionnuala Hickey, Derek P. Brazil, Noelynn Oliver, Finian Martin, Catherine Godson, and John Crean (2011) 'Cross talk between connective tissue growth factor and transforming growth factor-Beta1 via interaction with the type III TGF-Beta receptor modulates mesangial cell behavior with pathogenic implications for diabetic nephropathy'. Biochem J .  
Dr Neil Ferguson
Chi, C., Bach, A., Engstrom, A., Stromgaard, K., Lundstrom, P., Ferguson, N. & Jemth, P. (2011) 'Biophysical characterization of the complex between human papillomavirus E6 protein and synapse associated protein 97'. Journal of Biological Chemistry, 286 :3597-3606.  
O'Nuallain, B., Freir, D., Nicoll, A. Risse, E., Ferguson, N., Herrron, C., Collinge, J. & Walsh, D. (2010) 'Abeta dimers rapidly form synaptotoxic protofibrils'. Journal of Neuroscience, 30 :14411-14419.  
Arbely, E., Rutherford, T. J., Neuweiler, H., Sharpe, T. D., Ferguson, N. & Fersht, A. R. (2010) 'Carboxly pKa values and acid denaturation of BBL'. Journal of molecular biology, 403 :313-327.  
Professor William Gallagher
O'Neill A.J., Prencipe M., Dowling C., Fan Y., Mulrane L., Gallagher W.M., O'Connor D., O'Connor R., Devery A., Corcoran C., Rani S., O¿Driscoll L., Fitzpatrick J., R., Watson R.W.G. (2011) 'Characterisation and Manipulation of Docetaxel Resistant Prostate Cancer Cell Lines'. MOL CANCER .  
Gremel, G., Ryan, D., Rafferty, M., Lanigan, F., Hegarty, S., Lavelle, M., Murphy, I., Unwin, L., Joyce, C., Faller, W., McDermott, E.W., Sheahan, K., Ponten, F.,Gallagher W.M. (2011) 'Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma'. British Journal of Cancer, 105 (4):565-574.  
Lindsay, C. R., Lawn, S., Campbell, A. D., Faller, W. J., Rambow, F., Mort, R. L., Timpson, P., Li, A., Cammareri, P., Ridgway, R. A., Morton, J. P., Doyle, B., Hegarty, S., Rafferty, R., Murphy, I. G., McDermott, E. W., Sheahan, K., Pedone, K., Finn, A. J., Groben, P. A., Thomas, N. E., Hao, H., Carson, C., Norman, J. C., Machesky, L. M., Gallagher, W. M., Jackson, I. J., Van Kempen, L., Beermann, F., Der, C., Larue, L., Welch, H. C., Ozanne, B. W. Sansom, O. J. (2011) 'P-Rex1 is required for efficient melanoblast migration and melanoma metastasis'. Nature Communications .  
Magnusson, K., de Wit. M., Brennan, D. J., Johnson, L. B., McGee, S. F., Lundberg, E., Naicker, K., Klinger, R., Kampf, C., Asplund, A., Wester, K., Gry, M., Bjartell, A., Gallagher, W.M., Rexhepaj, E., Kilpinen, S., Kallioniemi, O. P., Belt, E., Goos, J., Meijer, G., Birgisson, H., Glimelius, B., Borrebaeck, C. A., Navani, S., Uhlén, M., O?Connor, D. P., Jirström, K., and Pontén, F. (2011) 'SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas'. American Journal of Surgical Pathology, 35 (7):937-948.  
Dahlman, A., Rexhepaj, E., Brennan, D. J., Gallagher, W. M., Gaber, A., Lindgren, A., Jirström, K., and Bjartell, A (2011) 'Evaluation of the prognostic significance of MSMB and CRISP3 in prostate cancer using automated image analysis'. Modern Pathology, 24 (5):708-719.  
Fitzgerald, K. T., Holladay, C. A., McCarthy, C., Power, K. A., Pandit, A., and Gallagher, W. M. (2011) 'Standardization of models and methods used to assess nanoparticles in cardiovascular applications'. Small, 7 (6):705-717.  
van der Meel, R., Symons, M. H., Kudernatsch, R., Kok, R. J., Schifflers, R. M., Storm, G., Gallagher, W. M., and Byrne, A. T. (2011) 'The VEGF/Rho GTPase signalling pathway: a promising target for antiangiogenic and anti-invasion therapy'. Drug Discovery Today, 16 (5-6):219-228.  
Devitt, E. J., Power, K. A., Lawless, M. W., Browne, J. A., Gaora, P. O., Gallagher, W. M., and Crowe, J. (2011) 'Early proteomic analysis may allow noninvasive identification of hepatitis C response to treatment with pegylated interferon α-2b and ribavirin'. European Journal of Gastroenterology & Hepatology, 23 (2):177-183.  
Dasari, S., Chambers, M. C., Codreanu, S. G., Liebler, D. C., Collins, B. C., Pennington, S. R., Gallagher, W. M. and Tabb, D. L. (2011) 'Sequence tagging reveals unexpected modifications in toxicoproteomics'. Chemical research in toxicology, 24 (2):204-216.  
Dowling, DP,Miller, IS,Ardhaoui, M,Gallagher, WM (2011) 'Effect of Surface Wettability and Topography on the Adhesion of Osteosarcoma Cells on Plasma-modified Polystyrene'. Biomaterials, 26 :327-347.  
Johnston, O,Cassidy, H,O'Connell, S,O'Riordan, A,Gallagher, W,Maguire, PB,Wynne, K,Cagney, G,Ryan, MP,Conlon, PJ,McMorrow, T (2011) 'Identification of beta 2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods'. Proteomics Clinical Applications, 5 :422-431.  
DeNardo, DG,Brennan, DJ,Rexhepaj, E,Ruffell, B,Shiao, SL,Madden, SF,Gallagher, WM,Wadhwani, N,Keil, SD,Junaid, SA,Rugo, HS,Hwang, ES,Jirstrom, K,West, BL,Coussens, LM (2011) 'Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy'. Cancer, 1 :54-67.  
Brennan, D. J., Laursen, H., O'Connor, D., Borgquist, S., Uhlén, M., Gallagher, W. M., Ponten, F., Millikan, R. C., Ryden, L., and Jirstrom, K. (2011) 'Tumor specific HMG-CoA reductase expression in primary pre-menopausal breast cancer predicts response to tamoxifen'. Breast Cancer Research, 13 (1).  
Fitzpatrick, S. F., Tambuwala, M. M., Bruning, U., Schaible, B., Scholz, C. C., Byrne, A., O'Connor, A., Gallagher, W. M., Lenihan, C. R., Garvey, J. F., Howell, K., Fallon, P. G., Cummins, E. P., and Taylor, C. T. (2011) 'An intact canonical NF-kB pathway is required for inflammatory gene expression in pesponse to hypoxia'. Journal of Immunology, 186 (2):1091-1096.  
Agnarsdottir, M, Sooman, L., Bolander, A., Strömberg, S., Rexhepaj, E., Bergqvist, M., Ponten, F., Gallagher, W.M., Lennartsson, J., Ekman, S., Uhlen, M., and Hedstrand, H. (2010) 'SOX10 expression in superficial spreading and nodular malignant melanomas'. Melanoma Research, 20 (6):468-478.  
Rexhepaj, E., Jirstrom, K., O'Connor, D. P., O'Brien, S. L., Landberg G., Duffy, M. J., Brennan, D. J., and Gallagher, W. M. (2010) 'Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer'. BMC Cancer, 10 .  
Dash, B. C., Rethore, G., Monaghan, M., Fitzgerald, K., Gallagher, W.M, and Pandit, A (2010) 'The influence of size and charge of chitosan/polyglutamic acid hollow spheres on cellular internalization, viability and blood compatibility'. Biomaterials, 31 (32):8188-8197.  
Ursini-Siegel, J., Cory, S., Zuo, D., Hardy, W. R., Rexhepaj, E., Lam, S., Schade, B., Jirstrom, K., Bjur, E., Piccirillo, C. A., DeNardo, D., Coussens, L. M., Brennan, D. J., Gallagher, W. M., Park, M., Pawson, T., Hallett, M. and Muller, W. J. (2010) 'Receptor tyrosine kinase signaling in breast cancer cells inhibits the adaptive immune response to favor a pro-tumorigenic state'. Cancer Research, 70 (20):7776-7787.  
Whyte, J., Thornton, L., McNally, S., McCarthy, S., Lanigan, F., Gallagher, W. M., Stein, T., and Martin, F. (2010) 'PKCdelta regulates cell polarisation and proliferation restriction during mammary acinus formation'. Journal of Cell Science, 123 (19):3316-3328.  
Power, KA, Fitzgerald, KT and Gallagher, WM. (2010) 'Examination of cell-host-biomaterial interactions via high-throughput technologies: A re-appraisal'. Biomaterials, 31 (26):6667-6674.  
Brennan, D. J., O'Connor, D. P., Rexhepaj, E., Ponten, F., and Gallagher, W. M. (2010) 'Antibody-based proteomics: fast-tracking molecular diagnostics in oncology'. Nature reviews. Cancer, 10 (9):605-617.  
Dr Jana Haase
Fjorback AW, Müller HK, Haase J, Raarup MK, Wiborg O. (2011) 'Modulation of the dopamine transporter by interaction with Secretory Carrier Membrane Protein 2'. Biochemical and Biophysical Research Communications, 406 (2):165-170.  
Dr Carmel Hensey
Aparicio, IM,Garcia-Herreros, M,O'Shea, LC,Hensey, C,Lonergan, P,Fair, T (2011) 'Expression, Regulation, and Function of Progesterone Receptors in Bovine Cumulus Oocyte Complexes During In Vitro Maturation'. Biology of reproduction, 84 :910-921.  
Dr Chandralal Hewage
Subasinghage AP, Green BD, Flatt PR, Irwin N, Hewage CM (2010) 'Metabolic and structural properties of human obestatin {1-23} and two fragment peptides'. Peptides, 31 (9):1697-1705.  
Mr Oktay Kaplan
Kaplan OI, Molla-Herman A, Cevik S, Ghossoub R, Kida K, Kimura Y, Jenkins P, Martens JR, Setou M, Benmerah A, Blacque OE. (2010) 'AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport'. Journal of Cell Science, 123 :3966-3977.  
Dr Breandán Kennedy
Cederlund ML, Vendrell V, Morrissey ME, Yin J, Gaora PÓ, Smyth VA, Higgins DG, Kennedy BN. (2011) 'mab21l2 transgenics reveal novel expression patterns of mab21l1 and mab21l2, and conserved promoter regulation without sequence conservation'. Developmental dynamics : an official publication of the American Association of Anatomists, 240 (4):745-754.  
Morrissey ME, Shelton S, Brockerhoff SE, Hurley JB, Kennedy BN (2011) 'PRE-1, a cis element sufficient to enhance cone- and rod- specific expression in differentiating zebrafish photoreceptors'. BMC Developmental Biology, 11 .  
Professor Therese Kinsella
Turner EC, Mulvaney EP, Reid HR& Kinsella BT (2011) 'Interaction of the Human Prostacyclin Receptor with the PDZ adapter protein PDZK1: Role in Endothelial Cell Migration and Angiogenesis'. Molecular Biology of the Cell, 22 (15):2664-2679.  
Helen M. Reid, Katarina Wikström, David J. Kavanagh, Eamon P. Mulvaney & B. Therese Kinsella. (2011) 'Interaction of Angio-associated Migragatory Cell Protein with the TP-Alpha and TP-Beta isoforms of the human Thromboxane A2 receptor'. Cellular Signalling, 23 (4):700-717.  
Turner, EC, Kavanagh, DJ, Mulvaney, EP, McLean, C, Wikstrom, K, Reid, HM & Kinsella, BT (2011) 'Identification of an interaction between the TPα and TPβ isoforms of the human thromboxane A2 receptor with protein kinase C-related kinase (PRK) 1'. J BIOL CHEM, 287 (17):15440-15457.  
Peter D. Donnellan, Cisca C. Kimbembe, Helen M. Reid & B. Therese Kinsella. (2011) 'Identification of a Novel Endoplasmic Reticulum Export Motif within the Eighth a-Helical Domain (a-H8) of the human Prostacyclin Receptor'. Biochimica et biophysica acta, 1808 :1202-1218.  
Turner EC, Mulvaney EP, Reid HR& Kinsella BT (2011) 'Interaction of the Human Prostacyclin Receptor with the PDZ adapter protein PDZK1: Role in Endothelial Cell Migration and Angiogenesis'. Molecular Cell Biology, 22 (15):2664-2679.  
Professor Jonathan Malthouse
Venneti KC, Malthouse JP, O'Harte FP, Hewage CM (2011) 'Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide'. Biochimica et biophysica acta, 1814 (7):882-888.  
Venneti, KC,Malthouse, JPG,O'Harte, FPM,Hewage, CM (2011) 'Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide'. Biochimica Et Biophysica Acta-Proteins and Proteomics, 1814 :882-888.  
Howe, N,Ceruso, M,Spink, E,Malthouse, JPG (2011) 'pH stability of the stromelysin-1 catalytic domain and its mechanism of interaction with a glyoxal inhibitor'. Biochimica Et Biophysica Acta-Proteins and Proteomics, 1814 :1394-1403.  
Dr Gethin McBean
McBean, G.J. (2011) 'The transsulfuration pathway: a source of cysteine for glutathione in astrocytes'. Amino Acids .  
Vines, A., McBean, G.J., Blanco-Fernández, A. (2010) 'A flow-cytometric method for continuous measurement of intracellular Ca2+ concentration'. Cytometry Part A, 77 (11):1091-1097.  
Dr Margaret McGee
O'Connor AE, Mc Gee MM, Likar Y, Ponomarev V, Callanan JJ, O'shea DF, Byrne AT, Gallagher WM (2011) 'Mechanism of cell death mediated by a BF(2) -chelated tetraaryl-azadipyrromethene photodynamic therapeutic: Dissection of the apoptotic pathway in vitro and in vivo'. INT J CANCER .  
Dr Tara McMorrow
Johnston O, Cassidy H, O'Connell S, O'Riordan A, Gallagher W, Maguire PB, Wynne K, Cagney G, Ryan MP, Conlon PJ, McMorrow T. (2011) 'Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods'. Proteomics Clinical Applications, 5 (7-8):422-431.  
O'Connell S, Slattery C, Ryan MP, McMorrow T. (2011) 'Identification of novel indicators of cyclosporine A nephrotoxicity in a CD-1 mouse model'. Toxicology & Applied Pharmacology, 252 (2):201-210.  
J. Lynch, S. Nolan, C. Slattery, R. Feighery, M.P. Ryan, T. McMorrow (2010) 'High-Mobility Group Box Protein 1: A Novel Mediator of Inflammatory-Induced Renal Epithelial-Mesenchymal Transition'. American Journal of Nephrology, 32 (6):590-602.  
H Cassidy, O Johnston, L Brennan, A O Riordan, P Conlon, MP Ryan, T Mc Morrow (2010) 'Metabolomic Analysis of Human(HOMO SAPIENS) Immunosuppressant Nephropathy Post Renal Transplantation'. IRISH J MED SCI, 7 .  
Professor Wim Meijer
Letek, M. et al. (2010) 'The genome of a pathogenic Rhodococcus: cooptive virulence underpinned by key gene acquisitions'. PLoS Genetics, 6 (9).  
Dr Cormac Declan Murphy
T. Fukuda, E.D. Miller, B.R. Clark, A. Alnauman, C.D. Murphy, P.R. Jensen and W. Fenical (2011) 'Structures and Biosynthesis of the Pyridinopyrones, Polyenepyrones from a Marine-Derived Streptomyces Species'. Journal of Natural Products, 74 :1773-1778.  
Misiak, K., Casey, E. and Murphy, CD (2011) 'Factors influencing 4-fluorobenzoate degradation in biofilm cultures of Pseudomonas knackmussii B-13'. Water Research, 45 (11):3512-3520. Available Online  
Amadio, J. and Murphy, C.D. (2011) 'Production of human metabolites of the anti-cancer drug flutamide via biotransformation in Cunninghamella species'. Biotechnology Letters, 33 :321-326.  
Hughes D, Clark BR, Murphy CD (2011) 'Biodegradation of polyfluorinated biphenyl in bacteria'. Biodegradation, 22 (4):741-749.  
Amadio, J., Gordon, K. and Murphy, C.D. (2010) 'Biotransformation of flurbiprofen by Cunninghamella species'. Applied and Environmental Microbiology, 76 :6299-6303.  
Dr Jens Erik Nielsen
Webb H, Tynan-Connolly BM, Lee GM, Farrell D, O'Meara F, Sondergaard CR, Teilum K, Hewage C, McIntosh LP, Nielsen LP (2011) 'Remeasuring HEWL pK(a) values by NMR spectroscopy: Methods, analysis, accuracy, and implications for theoretical pK(a) calculations'. Proteins, 79 (3):685-702.  
Johnston MA, Sondergaard CR, Nielsen JE (2011) 'Integrated prediction of the effect of mutations on multiple protein characteristics'. Proteins, 79 (1):165-178.  
Dr Kathy O'Boyle
Drennan J., Naughton C., Allen D., Hyde A., O'Boyle K., Felle P., Treacy M., Butler M. (2011) 'Patients' level of satisfaction and self-reports of intention to comply following consultation with nurses and midwifes with prescriptive authority: a cross-sectional survey'. International Journal of Nursing Studies, 48 (7):808-817.  
Dr John O'Connor
Watters O, O'Connor JJ (2011) 'A role for tumor necrosis factor-alpha in ischemia and ischemic preconditioning'. Journal of Neuroinflammation, 8 :87-98.  
Watters O, Pickering M, O'Connor J.J. (2011) 'Preconditioning effects of tumor necrosis factor-α and glutamate on calcium dynamics in rat organotypic hippocampal cultures'. Journal of Neuroimmunology, 234 (1-2):27-39.  
Dr Jim O'Gara
Cotter JJ, Maguire P, Soberon F, Daniels S, O'Gara JP, Casey E. (2011) 'Disinfection of meticillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a remote non-thermal gas plasma'. Journal of Hospital Infection, 78 (3):204-207. Available Online  
Rowe, S.E., Mahon, V., Smith, S.G. and O'Gara, J.P. (2011) 'A novel role for SarX in Staphylococcus epidermidis biofilm regulation'. Microbiology, 157 :1042-1049.  
Houston, P., Rowe, S.E., Pozzi, C., Waters, E.M. and O'Gara, J.P. (2011) 'An essential role for the major autolysin in the fibronectin-binding protein-mediated Staphylococcus aureus biofilm phenotype'. Infection and Immunity, 79 :1153-1165.  
Holland, L.M., Conlon, B. and O'Gara, J.P. (2011) 'Mutation of tagO reveals an essential role for wall teichoic acids in Staphylococcus epidermidis biofilm development'. Microbiology, 157 :408-418.  
Rawlinson L.B., O'Gara, J.P., Jones, D.S. and D.J. Brayden (2011) 'Resistance of Staphylococcus aureus to the cationic antimicrobial agent pDMAEMA is influenced by cell surface charge and hydrophobicity'. Journal of Medical Microbiology, 60 (7):968-976.  
Geoghegan, J.A., Corrigan, R.M.,Gruszka, D.T., Speziale, P., O'Gara, J.P., Potts, J.R. and T.J. Foster (2010) 'The role of surface protein SasG in biofilm formation by Staphylococcus aureus'. Journal of Bacteriology, 192 :5663-5673.  
Mr Fergal O'Meara
Webb H, Tynan-Connolly BM, Lee GM, Farrell D, O'Meara F, Sondergaard CR, Teilum K, Hewage C, McIntosh LP, Nielsen LP (2011) 'Remeasuring HEWL pK(a) values by NMR spectroscopy: Methods, analysis, accuracy, and implications for theoretical pK(a) calculations'. Proteins, 79 (3):685-702.  
Dr Margaret Worrall
Anguissola S, McCormack WJ, Morrin MA, Higgins WJ, Fox DM, Worrall DM (2011) 'Pigment Epithelium-Derived Factor (PEDF) Interacts with Transportin SR2, and Active Nuclear Import Is Facilitated by a Novel Nuclear Localization Motif'. PLoS ONE, 6 (10).  
de Koning PJ, Kummer JA, de Poot SA, Quadir R, Broekhuizen R, McGettrick AF, Higgins WJ, Devreese B, Worrall DM, Bovenschen N. (2011) 'Intracellular serine protease inhibitor SERPINB4 inhibits granzyme M-induced cell death'. PLoS ONE, 6 (8).  
de Koning, PJA,Kummer, JA,de Poot, SAH,Quadir, R,Broekhuizen, R,McGettrick, AF,Higgins, WJ,Devreese, B,Worrall, DM,Bovenschen, N (2011) 'Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death'. PLoS ONE, 6 .  
Dr Tadhg Ó'Cróinín
Mangan MW, Lucchini S, O Croinin T, Fitzgerald S, Hinton JC and Dorman CJ (2011) 'The nucleoid-associated protein HU controls three regulons that coordinate virulence, response to stress and general physiology in Salmonella enterica serovar Typhimurium'. Microbiology .  
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Conference Publications
Professor William Gallagher
Maher, S.G., McDowell, D.T., Murphy, S.A., Collins, B.C., Muldoon, C., Gallagher, W.M., Reynolds, J.V. (2011) Pre-treatment complement system serum protein levels predict response to neoadjuvant chemoradiation for oesophageal cancer The Annual Meeting of the Society of Academic and Research Surgery, 1 - 5  
Dolan, R.T., Penny, S., Kelly, C.M., (Kelly, Brennan, D.J., Rexhepaj, E., Jirstrom, K., Ponten, F., Uhlen, M., Gallagher, W.M., Kell, M.R (2011) Development of immunohistochemical surrogates for prediction of breast cancer patient outcome via high-throughput antibody generation and validation using tissue microarray technology The Annual Meeting of the Society of Academic and Research Surgery, 1 - 5  
Hayley, D., McKeen, H. D., Brennan, D. J., Hegarty, S., Lanigan, F., Jirstrom, K., Byrne, C., Yakkundi, A., McCarthy, H. O., Gallagher, W. M., and Robson, T. (2011) The emerging role of FK506-binding proteins as cancer biomarkers: a focus on FKBPL . In: Konstantin Panov (Queen's University Belfast, U.K.) and Paul Thompson (University of Ulster, Coleraine, U.K.) eds. Biochemical Society Irish Area Section Meeting - Signalling and Disease, 663 - 668  
Dahlman, A.K., Rexhepaj, E; Brennan, D.J., Gallagher, W.M., Gaber, A., Lindgren, A., Jirstrom, K., Bjartell, A. (2011) Automated image analysis confirms the predictive significance of MSMB in prostate cancer 26 Annual Congress of the European Association of Urology, I - XIV  
Dr Carmel Hensey
Aparicio, I. M. Garcia-Herreros, M. O'Shea, L. C. Hensey, C. Lonergan, P. Fair, T. (2011) Role of Progestrone and it's receptors on developmental competence of Oocytes in Cattle Reproduction and Fertility Development, Reproduction, Fertility and Development, 23, 227 - 227  
L. O'Shea, T. Fair, C. Hensey (2010) Dynamic Changes in Aven Expression during Oocyte Maturation and Early Embryonic Development in Xenopus laevis American Society for Cell Biology, Molecular Biology of the Cell, 21, (Suppl.) Abs 822,  
Professor Therese Kinsella
Mulvaney EP, Reid HM & B.T. Kinsella BT. (2011) Interaction of angio-associated migratory cell protein with the TPα and TPβ isoforms of the human thromboxane A2 receptor . In: FASEB J eds. Experimental Biology 2011, Washington DC, 25 - 1008.1 Available Online  
Mulvaney EP, Reid HM & B.T. Kinsella BT. (2011) Interaction of angio-associated migratory cell protein with the TPα and TPβ isoforms of the human thromboxane A2 receptor Prospects and Challenges for Therapeutic Targeting of Epoxyeicosanoids Minisymposium at Experimental Biology 2011, Washington DC, . - .  
Turner EC, Mulvaney EP, Reid HM & B.T. Kinsella BT. (2011) The human prostacyclin receptor contains a novel Rab11 binding domain that is regulated by . In: The FASEB Journal eds. Experimental Biology 2011, Washington DC, 25 - 628.8 Available Online  
Dr Tara McMorrow
Robert Radford, Craig Slattery, Michael Ryan, Tara McMorrow (2010) Deciliation of Kidney Epithelial Cells Is an Early marker of Carcinogenic Effects American Society of Cell Biology,  
Dr John O'Connor
Watters O, O'Connor JJ (2010) Modulatory effects of TNFalpha and glutamate pretreatment on calcium homeostasis and glutamate-induced calcium influx in rat organotypic hippocampal cultures Royal academy of medicine in Ireland biomedical sciences section annual meeting 2010,  
Corcoran AE, O'Connor JJ (2010) Acute effects of prolyl hydroxylase inhibiton on synaptic transmission and plasticity in the hippocampal rat slice Royal Academy of medicine in Ireland Biomedical sciences section annual meeting 2010,  
Corcoran A, O'Connor JJ (2010) The effects of hypoxia, prolyl hydroxylase inhibition and TNF-alpha on synaptic transmission in the rat hippocampus Winter Meeting British Pharmacology Society,  
Watters O, O'Connor JJ (2010) TNF-a And Glutamate Preconditioning Effects On Calcium Dynamics In Rat Hippocampal Cultures Winter Meeting British Pharmacology Society,  
Sheridan, G.K., Pickering, M., O'Connor, J.J., Moynagh, P.N., Murphy, K.J. (2010) Similar temporal oscillations in hippocampal NF-kB following spatial learning in rats and high-frequency stimulation of organotypic slice cultures Neuroscience Ireland Meeting,  
Sheridan, G.K., Pickering, M., Halley, P., O'Sullivan, N.C., O'Connor, J.J., Murphy, K.J. (2010) The chemokine, fractalkine (CX3CL1), modulates synaptic plasticity and is upregulated in the rat hippocampus following a spatial learning task Neuroscience Ireland Meeting,  
Batti, L., Taylor, C., O'Connor, J.J. (2010) A role for the prolyl hydroxylase inhibitor, DMOG, on synaptic transmission and neuroprotection in an ex vivo model of cerebral ischaemia Neuroscience Ireland Meeting,  
Sheridan, G.K., Pickering, M., O'Connor, J.J., Moynagh, P.N., Murphy, K.J. (2010) Similar temporal oscillations in hippocampal NF-kB following spatial learning in rats and high-frequency stimulation of organotypic slice cultures Neuroscience Ireland Meeting, TCD. Irish Journal of Medical Science,  
Corcoran A.E., O'Connor JJ (2010) Acute effects of proyly hydroxylase inhibition on synaptic transmission and plasticity in the rat hippocampal slice RCSI June, Irish Journal of Medical Science,  
Watters O, O'Connor JJ (2010) TNF-α And Glutamate preconditioning attenuates calcium mediated activity in the ca region of rat organotypic hippocampal cultures Neuroscience Ireland meeting UCD (Sept) Irish Journal of Medical Science,  
Dr Tadhg Ó'Cróinín
C. Shortt, E. Scanlan, B. Bourke and T. O Croinin (2011) Transcriptional regulation of chemotaxis and motility through DNA supercoiling SGM Irish Branch Meeting - Microbial pathogenesis the key to better therapies, Institute of Technology Tallaght,  
C. Shortt, Scanlan E, Bourke B and O Croinin T (2011) The role of DNA supercoiling in the regulation of motility in Campylobacter jejuni SGM Irish Branch Meeting - Microbial Viruses: Genomics Evolution and Application in Ecology, Biotechnology and Medicine, Queens University Belfast,  
E. Scanlan, C. Shortt, B. Bourke and T. O Croinin (2011) DNA supercoiling in Campylobacter jejuni : A potential global regulator of invasion SGM Irish Branch Meeting - Microbial pathogenesis the key to better therapies, Institute of Technology Tallaght,  
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Other Publications
Professor Jonathan Malthouse
Malthouse JPG (2010) Review of Pain Free Biochemistry by PC Engel, Wiley-Blackwell. Irish Medical Journal 2010 103, 287: Book Reviews.  
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