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'Il fait froid - Il 'fate' froid!'. Image by Ms Sinead Lindsay.

'Il fait froid - Il 'fate' froid!'. Image by Ms Sinead Lindsay.

UCD Biomolecular & Biomedical Science

UCD School of Biomolecular & Biomedical Science - Research Publications 2013/14

Below is the list of research publications for the UCD School of Biomolecular & Biomedical Science in the academic year 2013/14.




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Book Chapters

Professor Ciaran Regan
Ciaran M Regan (2014) 'Role of the environment, epigenetics and synapses in cognitive enhancement' In: Shira Knafo and Cesar Venero (eds). Cognitive Enhancement. US: Elsevier.  


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Peer Reviewed Journals

Dr Orina Belton
de Gaetano M, Dempsey E, Marcone S, James WG, Belton O (2013) Conjugated linoleic acid targets β2 integrin expression to suppress monocyte adhesion J IMMUNOL, 191 (8):4326-4336.  
McCarthy C, Lieggi NT, Barry D, Mooney D, de Gaetano M, James WG, McClelland S, Barry MC, Escoubet-Lozach L, Li AC, Glass CK, Fitzgerald DJ, Belton O (2013) 'Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid'. EMBO molecular medicine, 5 (9):1443-1457.  
Dr Oliver Blacque
Sebiha Cevik, Anna A. W. M. Sanders, Erwin Van Wijk, Karsten Boldt5, Lara Clarke, Jeroen van Reeuwijk, Yuji Hori, Nicola Horn, Lisette Hetterschijt, Anita Wdowicz, Andrea Mullins, Katarzyna Kida, Oktay I. Kaplan, Sylvia E. C. van Beersum, Ka Man Wu, Stef J. F. Letteboer, Dorus A. Mans, Toshiaki Katada, Kenji Kontani, Marius Ueffing, Ronald Roepman, Hannie Kremer,and Oliver E. Blacque. (2013) 'Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain'. PLoS Genetics.  
Mohan S, Timbers TA, Kennedy J, Blacque OE, Leroux MR (2013) 'Striated Rootlet and Nonfilamentous Forms of Rootletin Maintain Ciliary Function'. Current Biology.  
Professor Geraldine Butler
Sarah L. Maguire, Can Wang, Linda M. Holland, François Brunel, Cécile Neuvéglise, Jean-Marc Nicaud, Martin Zavrel, Theodore C. White, Kenneth H. Wolfe, and Geraldine Butler (2014) 'Zinc finger transcription factors displaced SREBP proteins as the major sterol regulators during Saccharomycotina evolution'. PLoS Genetics, :e1004076-e1004076.  
Connolly LA, Riccombeni A, Grózer Z, Holland LM, Lynch DB, Andes DR, Gácser A, Butler G. (2013) 'The APSES transcription factor Efg1 is a global regulator that controls morphogenesis and biofilm formation in Candida parapsilosis'. Molecular Microbiology, 90 (1):36-53.  
Dr Patrick Caffrey
Eimear De Poire, Niamh Stephens, Bernard Rawlings, Patrick Caffrey (2013) 'Engineered biosynthesis of disaccharide-modified polyene macrolides'. Applied and Environmental Microbiology, 79 (19):6156-6159.  
Dr Gerard Cagney
F?cking M, Lopez LM, English JA, Dicker P, Wolff A, Brindley E, Wynne K, Cagney G, Cotter DR (2014) 'Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia'. Molecular Psychiatry.  
English JA, Wynne K, Cagney G, Cotter DR (2013) 'Targeted Proteomics for Validation of Biomarkers in Early Psychosis'. Biological Psychiatry.  
Di Cara F, Duca E, Dunbar DR, Cagney G, Heck MM (2013) 'Invadolysin, a conserved lipid-droplet-associated metalloproteinase, is required for mitochondrial function in Drosophila'. Journal of Cell Science, 126 (Pt 20):4769-4781.  
Dr Jillian Casey
Gadancheva VG, Casey JP, Russell JD, McDaid J, Betts DR, Lynch SA. (2014) 'Vocal cord paralysis in association with 9q34 duplication'. Clinical Dysmorphology.  
Casey, J; McGettigan, P; Brosnahan, D; Curtis, E; Treacy, E; Ennis, S; Lynch, SA. (2014) 'Atypical Alstrom syndrome with novel ALMS1 mutations precluded by current diagnostic criteria'. European Journal of Medical Genetics, 57 (2-3):55-59. Available Online  
Professor Michael Duffy
Duffy MJ, Lamerz R, Haglund C, Nicolini A, Kalousová M, Holubec L, Sturgeon C. (2014) 'Tumor markers in colorectal cancer, gastric cancer and gastrointestinal stromal cancers: European group on tumor markers 2014 guidelines update'. INT J CANCER, 14 (11):2513-2522.  
Romagnoli M, Mineva ND, Polmear M, Conrad C, Srinivasan S, Loussouarn D, Barillé-Nion S, Georgakoudi I, Dagg Á, McDermott EW, Duffy MJ, McGowan PM, Schlomann U, Parsons M, Bartsch JW, Sonenshein GE. (2014) 'ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis'. EMBO molecular medicine, 6 (2):278-294.  
Duffy MJ, Crown J (2014) 'Precision Treatment for Cancer: Role of Prognostic and Predictive Markers'. Critical reviews in clinical laboratory sciences, 50 (1):30-45.  
Duffy MJ, Crown J (2013) 'Monitoring response to therapy in patients with cancer: is circulating DNA the answer?'. Annals of Translational Medicine, 2013 (1):24-25.  
Duffy MJ, Crown J (2013) 'Companion biomarkers: paving the pathway to personalized treatment for cancer'. Clinical Chemistry, 59 (10):1447-1456.  
Dr Neil Ferguson
Voros, J., Urbanek, A., Rautureau, G., O'Connor, M., Fisher, H. C., Ashcroft, A.E. & Ferguson, N. (2013) ': Large-scale production, structural and biophysical characterizations of the human hepatitis B virus polymerase'. Journal of Virology.  
Professor William Gallagher
Stephen F Madden, Colin Clarke, Britta Stordal, Mark S Carey, Russell Broaddus, William M Gallagher, John Crown, Gordon B Mills and Bryan T Hennessy. (2014) 'OvMark: a user-friendly system for the identification of prognostic biomarkers in publically available ovarian cancer gene expression datasets'. Molecular Cancer, 13 (241).  
O¿Leary, P. C., Terrile, M., Bajor, M., Gaj, P., Hennessy, B. T., Mills, G. B., Zagozdzon, A., O¿Connor, D. P., Brennan, D. J., Connor, K., Li, J., Gonzalez-Angulo, A., Sun, H., Pu, J., Pontén, F., Uhlén, M., Jirström, K., Nowis, D. A., Crown, J. P., Zagozdzon, R., and Gallagher, W. M. (2014) 'Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer'. Breast Cancer Research, 16 (4).  
Denecker, G. and Vandamme, N. and Akay, O. and Koludrovic, D. and Taminau, J. and Lemeire, K. and Gheldof, A. and De Craene, B. and Van Gele, M. and Brochez, L. and Udupi, G. M. and Rafferty, M. and Balint, B. and Gallagher, W. M. and Ghanem, G. and Huylebroeck, D. and Haigh, J. and van den Oord, J. and Larue, L. and Davidson, I. and Marine, J-C and Berx, G. (2014) 'Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression'. Cell Death and Differentiation, 21 (8):1250-1261.  
O'Hurley, Gillian and Sjosted, Evelina and Rahman, Arman and Li, Bo and Kampf, Caroline and Ponten, Fredrik and Gallagher, William M. and Lindskog, Cecilia (2014) 'Garbage in, garbage out: A critical evaluation of strategies used for validation of immunohistochemical biomarkers'. Molecular oncology, 8 (4, SI):783-798.  
Mulrane, Laoighse and Klinger, Rut and McGee, Sharon F. and Gallagher, William M. and O'Connor, Darran P. (2014) 'microRNAs: a new class of breast cancer biomarkers'. Expert Review of Molecular Diagnostics, 14 (3):347-363.  
O'Hurley, Gillian and Daly, Etain and O'Grady, Anthony and Cummins, Robert and Quinn, Cecily and Flanagan, Louise and Pierce, Aisling and Fan, Yue and Lynn, Miriam A. and Rafferty, Mairin and Fitzgerald, Dara and Ponten, Fredrik and Duffy, Michael J. and Jirstrom, Karin and Kay, Elaine W. and Gallagher, William M. (2014) 'Investigation of molecular alterations of AKT-3 in triple-negative breast cancer'. Histopathology, 64 (5):660-670.  
O'Hurley, Gillian and Prencipe, Maria and Lundon, Dara and O'Neill, Amanda and Boyce, Susie and O'Grady, Anthony and Gallagher, William M. and Morrissey, Colm and Kay, Elaine W. and Watson, R. William G. (2014) 'The Analysis of Serum Response Factor Expression in Bone and Soft Tissue Prostate Cancer Metastases'. Prostate, 74 (3):306-313.  
Nyamundanda, G., Gormley, I.C., Fan,Y., Gallagher, W.M. and Brennan, L. (2013) 'MetSizeR: selecting the optimal sample size for metabolomic studies using an analysis based approach'. BMC Bioinformatics.  
Dr Carmel Hensey
O'Shea LC, Hensey C, Fair T (2013) 'Progesterone regulation of AVEN protects bovine oocytes from apoptosis during meiotic maturation'. Biology of reproduction, 89 (6).  
Lynne O'Shea, Trudee Fair and Carmel Hensey (2013) 'Aven is dynamically regulated during Xenopus oocyte maturation and is required for oocyte survival'. Cell Death & Disease, 4 (11).  
Dr Caroline Herron
Charles Métais1, Kathryn Brennan1, Alex J. Mably1, Michael Scott1, Dominic M. Walsh1, Caroline E. Herron1 (2013) 'Simvastatin Treatment Preserves Synaptic Plasticity in AβPPswe/ PS1dE9 Mice'. Journal of Alzheimers Disease.  
Andrew J. Nicoll1, Silvia Panico2,w, Darragh B. Freir1,3, Daniel Wright1, Cassandra Terry1, Emmanuel Risse1, Caroline E. Herron3, Tiernan¿Malley3,4, Jonathan D.F. Wadsworth1, Mark A. Farrow1, Dominic M. Walsh4, Helen R. Saibil2 & John Collinge1 (2013) 'Amyloid-b nanotubes are associated with prion protein-dependent synaptotoxicity'. Nature Communications, (DOI: 10.1038/ncomms3):1-9.  
Dr Chandralal Hewage
Kenny, O., Smyth, T. J., Hewage, C. M., Brunton, N. P., McLoughlin, P. (2014) 4-hydroxyphenylacetic acid derivatives of inositol from dandelion (Taraxacum officinale) root characterised using LC-SPE-NMR and LC-MS techniques Phytochemistry, 98 (0):197-203. Available Online  
Kenny, O.a d and Smyth, T.J.a and Walsh, D.b and Kelleher, C.T.c and Hewage, C.M.d and Brunton, N.P.a (2014) 'Investigating the potential of under-utilised plants from the Asteraceae family as a source of natural antimicrobial and antioxidant extracts'. Food Chemistry, 161 :79-86. Available Online  
Dr Breandán Kennedy
Reynolds AL, Kent D, Kennedy BN. (2014) 'Current and emerging therapies for ocular neovascularisation'. Advances in experimental medicine and biology, 2014;801: :797-804.  
Sasore T, Reynolds AL, Kennedy BN. (2014) 'Targeting the PI3K/Akt/mTOR pathway in ocular neovascularization'. Advances in experimental medicine and biology, 801 :805-811.  
Shine L, Kilty C, Gross J, Kennedy B. (2014) 'Vacuolar ATPases and their role in vision'. Advances in experimental medicine and biology, 801 :97-103.  
Sasore T, Kennedy B. (2014) 'Deciphering Combinations of PI3K/AKT/mTOR Pathway Drugs Augmenting Anti-Angiogenic Efficacy In Vivo'. PLoS ONE.  
Deeti S, O'Farrell S, Kennedy BN. (2013) 'Early safety assessment of human oculotoxic drugs using the zebrafish visualmotor response'. Journal of Pharmacol Toxicol Methods, 30 (69).  
Professor Therese Kinsella
Keating GL, Reid HM, Eivers SB, Mulvaney EP & Kinsella BT. (2014) 'Transcriptional Regulation of the Human Thromboxane A2 Receptor Gene by Wilms' tumour (WT)1and hypermethylated in cancer (HIC) 1 in Prostate and Breast Cancer'. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms, 1839 (6):467-492.  
Professor Jonathan Malthouse
Wild AA, Fennell K, Morgan GG, Hewage CM, Malthouse JP (2014) 'A 13C-NMR study of azacryptand complexes'. Dalton transactions (Cambridge, England : 2003), 43 :13557-13562.  
Cleary JA, Doherty W, Evans P, Malthouse JPG (2014) 'Hemiacetal stabilization in a chymotrypsin inhibitor complex and the reactivity of the hydroxyl group of the catalytic serine residue of chymotrypsin'. Biochimica Et Biophysica Acta-Proteins and Proteomics, 1844 :1119-1127.  
Dunny E, Doherty W, Evans P, Malthouse JP, Nolan D, Knox AJ (2013) 'Vinyl sulfone-based peptidomimetics as anti-trypanosomal agents: design, synthesis, biological and computational evaluation'. Journal of medicinal chemistry, 56 (17):6638-6650.  
Dr Gethin McBean
Rojo, A.I., McBean, G., Cindric, M., Egea, J. Lopez, M.G., Rada, P, Zarkovic, N, Cuadrado, A. (2014) 'Redox control of microglial function: molecular mechanisms and functional significance'. Antioxidants & Redox Signaling, 21 (12):1766-1801.  
Dr Margaret McGee
Annibali D, Whitfield JR, Favuzzi E, Jauset T, Serrano E, Cuartas I, Redondo-Campos S, Folch G, Gonzàlez-Juncà  A, Sodir NM, Massó-Vallés D, Beaulieu ME, Swigart LB, Mc Gee MM, Somma MP, Nasi S, Seoane J, Evan GI, Soucek L (2014) 'Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis'. Nature Communications, 5.  
Dr Hilary McMahon
Molloy B, McMahon HE. (2013) 'A cell biased effect of estrogen in prion infection'. Journal of Virology.  
Dr Tara McMorrow
Sumayao R, McEvoy B, Martin-Martin N, McMorrow T, Newsholme P. (2013) 'Cystine dimethylester loading promotes oxidative stress and a reduction in ATP independent of lysosomal cystine accumulation in a human proximal tubular epithelial cell line'. Experimental Physiology, 98 (10):1505-1517.  
H. Cassidy, J.Slyne, H. Frain, C. Slattery , M.P. Ryan, T. McMorrow (2013) 'High-Throughput Proteomic Approaches to the Elucidation of Potential'. Proteome science, 1 (2):159-179.  
Professor Wim Meijer
Wang, X; Coulson, GB; Miranda CasoLuengo, AA; Miranda CasoLuengo, R; Hondalus, MK; Meijer, WG (2014) 'IcgA is a virulence factor of Rhodococcus equi modulating intracellular growth'. Infection and Immunity, 82 (5):1793-1800.  
Whittingham, JL; Blagova, EV; Finn, CE; Luo, H; Miranda-CasoLuengo, R; Turkenburg, JP, Leech, AP; Walton, PH; Murzin, AG; Meijer, WG; Wilkinson, AJ (2014) 'Structure of the virulence-associated protein VapD from the intracellular pathogen Rhodococcus equi'. Acta Crystallographica Section D-Biological Crystallography, 70 :2139-2151.  
Maischberger, E; Cummins, CA; Fitzpatrick, E; Gallagher, ME; Worrall, S;Rousseau, K; Thornton, DJ; Meijer, WG; Miranda-CasoLuengo, R; Duggan, VE;Carrington, SD; Irwin, JA; Reid, CJ (2013) ''The expression of mucin genes and the presence of mucin gene products in the equine endometrium''. Research in Veterinary Science, 95 (1):169-175.  
Cauchard, S; Giguère, S; Venner, M; Muscatello, G; Cauchard, J; Cohen, ND; Haas, A; Hines, SA; Hondalus, MK; Horohov, DW; Meijer, WG; Prescott, JF; Vázquez-Boland, J (2013) 'Rhodococcus equi research 2008-2012: Report of the Fifth International Havemeyer Workshop'. Equine Veterinary Journal, 45 :523-526.  
Liu, L; Tharmalingam, T; Maischberger, E; Miranda-CasoLuengo, R; Meijer, WG; Rudd, PM; Irwin, JA (2013) 'A HPLC-based glycoanalytical protocol allows the use of natural O-glycans derived from glycoproteins as substrates for glycosidase discovery from microbial culture'. Glycoconjugate journal, 30 (8):791-800.  
Layton, BA; Cao, Y; Ebentier, DL; Hanley, K; Ballesté, E; Brandão, J; Byappanahalli, M; Converse, R; Farnleitner, AH; Gentry-Shields, J; Gidley, ML; Gourmelon, M; Lee, CS; Lee, J; Lozach, S; Madi, T; Meijer, WG; Noble, R; Peed, L; Reischer, GH; Rodrigues, R; Rose, JB; Schriewer, A; Sinigalliano, C; Srinivasan, S; Stewart, J; Van De Werfhorst, LC; Wang, D; Whitman, R; Wuertz, S; Jay, J; Holden, PA; Boehm, AB; Shanks, O; Griffith, JF (2013) 'Performance of human fecal anaerobe-associated PCR-based assays in a multi-laboratory method evaluation study'. Water Research, 47 (18):6897-6908.  
Raith, MR; Kelty, CA; Griffith, JF; Schriewer, A; Wuertz, S; Mieszkin, S; Gourmelon, M; Reischer, GH; Farnleitner, AH; Ervin, JS; Holden, PA; Ebentier, DL; Jay, JA; Wang, D; Boehm, AB; Aw, TG; Rose, JB; Balleste, E; Meijer, WG; Sivaganesan, M; Shanks, O (2013) 'Comparison of PCR and quantitative real-time PCR methods for the characterization of ruminant and cattle fecal pollution sources'. Water Research, 47 (18):6921-6928.  
Schriewer, A; Goodwin, KD; Sinigalliano, CD; Cox, A; Wanless, D; Bartkowiak, J; Ebentier, DL; Hanley, KT; Ervin, J; Deering, LA; Shanks, OC; Peed, LA; Meijer, WG; Griffith, JF; SantoDomingo, J; Jay, JA; Holden, PA; Wuertz, S (2013) 'Performance evaluation of canine-associated Bacteroidales assays in a multi-laboratory comparison study'. Water Research, 47 (18):6909-6920.  
Sinigalliano, C.D., J. Erven, L.C. van de Werfhorst, B. Badgley, E. Balleste, J. Bartkowiak, A.B. Boehm, M. Byappanahalli, K.D. Goodwin, M. Gourmelon, J. Griffith, P.A. Holden, J. Jay, B. Layton, C. Lee, J. Lee, W.G. Meijer, R. Noble, M. Raith, H. Ryu, M/J. Sadowsky, A. Schriewer, D. Wanless, R. Whitman, S. Wuertz, J.W. Santo Domingo (2013) 'Multi-laboratory evaluations of the performance of Catellicoccus marimammalium PCR assays developed to target gull fecal sources'. Water Research, 47 (18):6883-6896.  
Dr Raul Miranda Caso Luengo
Whittingham, JL; Blagova, EV; Finn, CE; Luo, H; Miranda-CasoLuengo, R; Turkenburg, JP, Leech, AP; Walton, PH; Murzin, AG; Meijer, WG; Wilkinson, AJ (2014) 'Structure of the virulence-associated protein VapD from the intracellular pathogen Rhodococcus equi'. Acta Crystallographica Section D-Biological Crystallography, 70 :2139-2151.  
Wang X, Coulson GB, Miranda-Casoluengo AA, Miranda-Casoluengo R, Hondalus MK, Meijer WG (2014) 'IcgA (Orf5) is a virulence factor of Rhodococcus equi modulating intracellular growth'. Infection and Immunity, IAI.01670-13. Available Online  
Liu, L; Tharmalingam, T; Maischberger, E; Miranda-CasoLuengo, R; Meijer, WG; Rudd, PM; Irwin, JA (2013) 'A HPLC-based glycoanalytical protocol allows the use of natural O-glycans derived from glycoproteins as substrates for glycosidase discovery from microbial culture'. Glycoconjugate journal, 30 (8):791-800.  
Dr Cormac Declan Murphy
Winn, M; Habimana, O; Casey, E; Murphy, C (2014) 'Characterisitics of Streptomyces griseus biofilms in continuous flow tubular reactors'. FEMS MICROBIOL LETT, 352 :157-164.  
Kavanagh, E; Winn, M; NicGabhann, C; O'Connor, NK; Beier, P; Murphy CD (2014) 'Microbial biotransformation of aryl sulfanylpentafluorides'. Environmental Science and Pollution Research, 21 :753-758.  
Shaughnessy, M; Harsanyi, H; Li, J; Bright, T; Murphy, C; Sandford, G. (2014) 'Targeted fluorination of a non-steroidal anti-inflammatory drug to prolong metabolic half-life'. Chemmedchem, 9 :733-736.  
Robertson, K; Murphy, CD; Paradisi, F (2013) 'The Synthesis and Biological Testing of Bacilysin Analogues'. Amino Acids, 45 (5):1157-1168.  
Dr Keith Murphy
Sheridan, G.K., Pickering, M., Watters, O., Halley, P.G., O¿Sullivan, N.C., Mooney, C., O¿Connor, J.J., Murphy, K.J. (2014) 'CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity'. Frontiers in Cellular Neuroscience, 8 :233-243.  
Sheridan, G.K., Moeendarbary E., Pickering M., O'Connor J.J., Murphy K.J. (2014) 'Theta-burst stimulation of hippocampal slices induces network-level calcium oscillations and activates analogous gene transcription to spatial learning'. PLoS ONE, 9 (6):e100546-e100546.  
Power BJ, O'Reilly G, Murphy R, Murphy KJ, Pickering M, Jones JF (2014) 'Normal nerve striations are altered in the Trembler-J mouse, a model of'. Muscle & Nerve.  
Watters, O., Pickering, M., Murphy, R., Murphy, K., O'Connor J.J (2014) 'Automated analysis of intracellular calcium fluorescence in rat organotypic hippocampal cultures: comparison to a manual, observer based method'. Journal of Neuroscience Methods, 223 :20-29.  
Sheridan GK, Murphy KJ (2013) 'Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre'. Open Biology, 6 (12).  
Dr Kathy O'Boyle
Downey, C., Daly, F., O'Boyle, KM (2013) 'An in vitro approach to assessing a potential drug interaction between MDMA (ecstasy) and caffeine'. Toxicology in Vitro. Available Online  
Dr David O'Connell
Graham K. Sheridan, Anita Wdowicz, Mark Pickering, Orla Watters, Paul Halley, Niamh C. O¿Sullivan, Claire Mooney, David J. O¿Connell, John J. O¿Connor and Keith J. Murphy (2014) 'CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity'. Frontiers in Cellular Neuroscience, 8 (233):1-15.  
Lalioti VS, Ilari A, O'Connell DJ, Poser E, Sandoval IV, Colotti G (2014) 'Sorcin links calcium signaling to vesicle trafficking, regulates polo-like kinase 1 and is necessary for mitosis'. PLoS ONE, 9 (1). Available Online  
Dr Darran O'Connor
O Leary PC, Terrile M, Bajor M, Gaj P, Hennessy BT, Mills GB, Zagozdzon A, O'Connor DP, Brennan DJ, Connor K, Li J, Gonzalez-Angulo AM, Sun HD, Pu JX, Pontén F, Uhlén M, Jirström K, Nowis DA, Crown JP, Zagozdzon R, Gallagher WM. (2014) 'Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer'. Breast Cancer Research.  
Mulrane L, Klinger R, McGee SF, Gallagher WM, O'Connor DP. (2014) 'microRNAs: a new class of breast cancer biomarkers'. Expert Review of Molecular Diagnostics.  
Mulrane L, Gallagher WM & O¿Connor DP (2014) 'A novel mechanism of regulation of the anti-metastatic miR-31 by EMSY in breast cancer'. Breast Cancer Research.  
Mulrane L, McGee SF, Gallagher WM & O'Connor DP (2013) 'microRNA Dysregulation in Breast Cancer'. Cancer Research.  
Dr John O'Connor
Sheridan, G.K., Pickering, M., Watters, O., Halley, P.G., O¿Sullivan, N.C., Mooney, C., O¿Connor, J.J., Murphy, K.J. (2014) 'CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity'. Frontiers in Cellular Neuroscience, 8 :233-243.  
Sheridan, G.K., Moeendarbary E., Pickering M., O'Connor J.J., Murphy K.J. (2014) 'Theta-burst stimulation of hippocampal slices induces network-level calcium oscillations and activates analogous gene transcription to spatial learning'. PLoS ONE, 9 (6):e100546-e100546.  
Wall, A., Corocoran, A., O'Halloran, K., O' Connor, J.J. (2014) 'Effects of prolyl hydroxylase inhibition and chronic intermittent hypoxia on synaptic plasticity in the rat hippocampus'. Neurobiology of Disease, 62 :8-17.  
Watters, O., Pickering, M., Murphy, R., Murphy, K., O'Connor J.J (2014) 'Automated analysis of intracellular calcium fluorescence in rat organotypic hippocampal cultures: comparison to a manual, observer based method'. Journal of Neuroscience Methods, 223 :20-29.  
Sheridan GK, Wdowicz A, Pickering M, Watters O, Halley P, O'Sullivan NC, Mooney C, O'Connell DJ, O'Connor JJ, Murphy KJ (2014) 'CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity'. Frontiers in Cellular Neuroscience, 8.  
Corcoran, A., Kunze, R., Harney, S.C., Breier, G., Marti, H.H., O'Connor, J.J. (2013) 'A role for prolyl hydroxylase domain proteins in hippocampal synaptic plasticity'. Hippocampus, 23 (10):861-872.  
Professor Kevin O'Connor
Cerrone F, Duane G, Casey E, Davis R, Belton I, Kenny ST, Guzik MW, Woods T, Babu RP, O'Connor K. (2014) 'Fed-batch strategies using butyrate for high cell density cultivation of Pseudomonas putida and its use as a biocatalyst'. Applied Microbiology and Biotechnology, 98 :9217-9228. Available Online  
Davis R, Kataria R, Cerrone F, Woods T, Kenny S, O'Donovan A, Guzik M, Shaikh H, Duane G, Gupta VK, Tuohy MG, Padamatti RB, Casey E, O'Connor KE (2013) 'Conversion of grass biomass into fermentable sugars and its utilization for medium chain length polyhydroxyalkanoate (mcl-PHA) production by Pseudomonas strains'. Bioresource Technology, 150C :202-209.  
Casey WT, Nikodinovic-Runic J, Fonseca Garcia P, Guzik MW, McGrath JW, Quinn JP, Cagney G, Prieto MA, O'Connor KE (2013) 'The effect of polyphosphate kinase gene deletion on polyhydroxyalkanoate accumulation and carbon metabolism in Pseudomonas putida?KT2440. Environmental microbiology reports, 5 (5):740-746.  
Cerrone F, Choudhari SK, Davis R, Cysneiros D, O'Flaherty V, Duane G, Casey E, Guzik MW, Kenny ST, Babu RP, O'Connor K (2013) 'Medium chain length polyhydroxyalkanoate (mcl-PHA) production from volatile fatty acids derived from the anaerobic digestion of grass'. Applied Microbiology and Biotechnology, 98 :611-620.  
Dr Niamh O'Sullivan
Menzies FM, Garcia-Arencibia M, Imarisio S, O'Sullivan NC, Ricketts T, Kent BA, Rao MV, Lam W, Green-Thompson ZW, Nixon RA, Saksida LM, Bussey TJ, O'Kane CJ, Rubinsztein DC (2014) 'Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity'. Cell death and differentiation.  
Sheridan GK, Wdowicz A, Pickering M, Watters O, Halley P, O'Sullivan NC, Mooney C, O'Connell DJ, O'Connor JJ, Murphy KJ (2014) 'CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity'. Frontiers in Cellular Neuroscience, 8.  
Dr Mark Pickering
Sheridan, G.K., Pickering, M., Watters, O., Halley, P.G., O¿Sullivan, N.C., Mooney, C., O¿Connor, J.J., Murphy, K.J. (2014) 'CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity'. Frontiers in Cellular Neuroscience, 8 :233-243.  
Sheridan, G.K., Moeendarbary E., Pickering M., O'Connor J.J., Murphy K.J. (2014) 'Theta-burst stimulation of hippocampal slices induces network-level calcium oscillations and activates analogous gene transcription to spatial learning'. PLoS ONE, 9 (6):e100546-e100546.  
Power BJ, O'Reilly G, Murphy R, Murphy KJ, Pickering M, Jones JF (2014) 'Normal nerve striations are altered in the Trembler-J mouse, a model of'. Muscle & Nerve.  
Watters, O., Pickering, M., Murphy, R., Murphy, K., O'Connor J.J (2014) 'Automated analysis of intracellular calcium fluorescence in rat organotypic hippocampal cultures: comparison to a manual, observer based method'. Journal of Neuroscience Methods, 223 :20-29.  
Sheridan GK, Wdowicz A, Pickering M, Watters O, Halley P, O'Sullivan NC, Mooney C, O'Connell DJ, O'Connor JJ, Murphy KJ (2014) 'CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity'. Frontiers in Cellular Neuroscience, 8.  
Professor Ciaran Regan
Rendeiro C, Foley A, Lau VC, Ring R, Rodriguez-Mateos A, Vauzour D, Williams CM, Regan C, Spencer JP (2014) 'A role for hippocampal PSA-NCAM and NMDA-NR2B receptor function in flavonoid-induced spatial memory improvements in young rats'. Neuropharmacology, 79 :335-344.  
Foley AG, Cassidy AW, Regan CM (2014) 'Pentyl-4-yn-VPA, a histone deacetylase inhibitor, ameliorates deficits in social behavior and cognition in a rodent model of autism spectrum disorders'. European Journal of Pharmacology.  
CM Regan (2014) 'Decisions, dopamine and degeneracy in complex biological systems'. Neuroscience and Neuroeconomics.  
Professor Mike Scott
Métais C, Brennan K, Mably AJ, Scott M, Walsh DM, Herron CE. (2014) 'Simvastatin treatment preserves synaptic plasticity in AβPPswe/PS1dE9 mice'. Journal of Alzheimer's disease : JAD, 39 (2):315-329.  
Dr Sungyoung Shin
Ho-Sung Lee, Chae Young Hwang, S.-Y. Shin, Ki-Sun Kwon and Kwang-Hyun Cho (2014) 'The MLK3-mediated positive feedback loop is crucial for ROS-dependent cell fate determination'. Science signaling.  
Dongkwan Shin, Ik Soo Kim, Ji Min Lee, S.-Y. Shin, Jong-Hoon Lee, Sung Hee Baek, and Kwang-Hyun Cho (2014) 'RORalpha-mediated Network Switch is Crucial for the Regulation of Cell Proliferation'. Journal of Molecular Cell Biology (JMCB).  
Dr Peadar Ó Gaora
Walsh CA, Bolger JC, Byrne C, Cocchiglia S, Hao Y, Fagan A, Qin L, Cahalin A, McCartan D, McIlroy M, O'Gaora P, Xu J, Hill AD, Young LS (2014) 'Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis'. Cancer research, 74 (9):2533-2544.  


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Conference Publications

Professor Jonathan Malthouse
Malthouse, J.P.G., Howe, N., Petrillo, L., O'Donohoe, C. and Cleary, J (2014) Quantifying the potency of inhibitor warheads with serine and cysteine proteases Gordon Research conference on Proteolytic Enzymes & Their Inhibitors,  
Cleary, J., Doherty, W., Evans, P. and Malthouse, J.P.G (2014) Observing Low Barrier Hydrogen Bonds by 1H-NMR in Chymotrypsin Gordon Research conference on Proteolytic Enzymes & Their Inhibitors,  
Petrillo, T. and Malthouse, JPG. (2013) Determination of the effective molarity of the active site serine in α-chymotrypsin The 2nd Irish NMR Meeting, Trinity Biomedical Sciences Institute, Trinity College Dublin,  
Dr John O'Connor
Mukandala, G., Wall., A.M., O'Connor J.J. (2014) The effects of thalidomide analogues on synaptic plasticity after acute hypoxia in the rat hippocampus are modulated by p38map kinase but not cox-2 inhibition Section Biomedical Sciences, RAMI,  
Audrey M. Wall, Gatambwa Mukandala, John J. O'Connor. (2013) A novel role for tumor necrosis factor-α in synaptic plasticity after acute hypoxia in the rat dentate gyrus Irish Journal of Medical Sciences Volume 183,  
Professor Michael P Ryan
Long, M., O'Leary, F., Ryan, M. and Looby, M. (2013) Deep excavations in Irish glacial deposits Proceedings 18th. International Conference on Soil Mechanics and Geotechnical Engineering (ISCMGE), Paris, 2039 - 2042  
Professor Michael Ryan
Long, M., O'Leary, F., Ryan, M. and Looby, M. (2013) Deep excavations in Irish glacial deposits Proceedings 18th. International Conference on Soil Mechanics and Geotechnical Engineering (ISCMGE), Paris, 2039 - 2042  


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Other Publications

Professor William Gallagher
Nyamundanda, G., Gormley, I.C., Fan, Y., Gallagher, W and Brennan, L. (2013) MetSizeR: a statistical tool for estimating sample sizes for metabolomic experiments. Software.  


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