Biotechnology and Synthetic Biology

Investigating the application and manipulation of biological materials and systems for their specific utilities in processes and products, biotechnology is the application of living systems to make or modify products or processes for specific use.  All of the basic subject areas of the BSc and MSc programmes in SBBS are intertwined with biotechnology.  The research efforts of the investigators in the School cover medical, industrial and environmental biotechnology.

Our researchers in the area of biotechnology are based in state-of-the-art labs within highly collaborative environments.

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Research Interests:  Antibiotics; Antifungals; micro-organisms; synthetic boiology

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Research Interests: Protein interactions; network biology; synthetic biology; bioinformatics; mass spectrometry

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Research Interests:  NMR Spectroscopy; mocecular modelling; peptides; structural biology; diabetes; antimicrobial; GIP structure; GPCR structure.

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Research Interests:  G-coupled protein receptors; cannabinoids; cell signalling; pharmacology; neuroscience; imaging of cytoskeletal dynamics; therapeutic target dcvelopment.

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Research Interests:  enzymology; biological NMR; proteases; protease inhibition; glyoxal inhibitors, 13C- NMR, development of Apple and Android applications.

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Research Interests: Mechanisms of Disease, Cancer, Mitotic Catastrophe, Mitotic Cell death, Genome stability, Peptidyl prolyl isomerases, Cyclophilin A, Bcl-2 proteins.

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Research Interests: biochemical mechanisms behind Prion diseases; Therapeutics; link between Prion disorders and Alzheimer's disease; aging; oxidative stress.

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Research Interests: Host pathogen interaction, streptococci, staphylococci, E. coli, platelets, glycolipids, lipoteichoic acid, lipopolysaccharide, CD36, infection biology.

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Research Interests: biocatalysis, biotransformation, organofluorine, microbial models of drug metabolism.

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Research Interests:  biotherapeutics; biotechnology;  activity of the calcium binding protein secretagogin in neuronal cells; protein networks.

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Research Interests: biocatalysis and metabolic engineering; biodegradable polymer synthesis by bacteria; Enzymes as biocatalysts in the transformation of aromatic and aliphatic substrates.

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The Integrative Biology Laboratory or "R" Lab is a pluri-disciplinary laboratory focusing on the functions of epithelia. We use physics, chemistry, engineering, molecular and cellular techniques to study secretory pathways. We combine an evolutionary approach using new biophysical and optical methods ranging from cell "morphing" to Light Sheet Microscopy for 3D imaging. Our ultimate goal is to achieve a continuum of knowledge from single bacterium excretion capacity to complex tissue secretion ability in an organism context.

We also provide advice and optical set-up to research groups and collaborate extensively with the private sector in a unique sustainable and open source approach.  Emmanuel Reynaud is a member of the UCD Biomedical Engineering Centre

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Research Interests: Absorptive capacities in the biotechnology industry;  CEO leadership of biotechnology firms; Supervenience as a model to reconnect absorptive capacity to the individual.

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