Blog

The French Connection at SBI: A Bastille Day special

Monsieur le Professeur Jonathan Bond takes an in-depth look at the French side of SBI.

12 July, 2019 Read More

Modeling Treatments for RAS- and RAF-mutant Cancers

Cancers, particularly melanomas, bearing oncogenic NRAS and HRAS mutations are currently considered undruggable.

01 July, 2019 Read More

Haematopoetic Stem Cell Transplantation (HSCT): What We Can Do to Fight Complications

PhD student Simeng Li writes about the Eissner Group's aim to quantify the risk of endothelial damage for individual donor-recipient pairs in a paediatric cohort of patients.

17 June, 2019 Read More

Working in systems biology: how I reconciled my first love of mathematics with my experience in biology

PhD student Laura Tuffery gives a personal account of the factors that led her to became a researcher at Systems Biology Ireland.

04 June, 2019 Read More

Learning how to navigate.

Using classical systems biology methods, the Fey group has developed a study that suggests animals use important landmarks as signposts in learning direction and distance information.

16 May, 2019 Read More

Ebhardt Group Updates

Dr Ebhardt has been involved in multiple studies with a focus on pharmacological interventions in prostate cancer.

15 April, 2019 Read More

Patient and Public Involvement Offers Insightful Experience for Researchers

SBI postdoc Niamh O'Driscoll explains how patient and public involvement (PPI) has impacted her research as she works to solve difficult problems in ovarian cancer therapies.

01 April, 2019 Read More

Personalised nutrition in Elderly

MSCA TOPMed10 fellowship - Research by Dr. Caoileann Murphy

08 November, 2018 Read More

Investigating the interplay of Epigenetics and Cancer Signalling in acquired Drug Resistance in Melanoma

MSCA TOPMed10 fellowship - Research by Dr. Ariane Watson

15 August, 2018 Read More

Overcoming resistance of RAS-mutant cells to RAF inhibitors by combining structurally different inhibitors can open new strides in targeted therapy.

Malignant melanoma is a skin cancer primarily caused by UV exposure. Due to its tendency to spread rapidly and its resistance to drugs, melanomas rank among the deadliest cancers.

25 July, 2018 Read More

New Prognostic Marker in Childhood and Adolescent Leukaemia

Prof. Jonathan Bond discusses his recent work published in the academic journal, "Leukemia".

17 July, 2018 Read More

SBI Deputy Director Boris Kholodenko Elected to Royal Irish Academy

Prof. Boris Kholodenko is among 28 new members who were welcomed to the Royal Irish Academy on Friday, the 25th May, 2018.

20 June, 2018 Read More

Melanoma Awareness Event May 14th, 2018

Monday 14th May 2018 marked the first Skin Cancer Awareness Event at UCD.

15 May, 2018 Read More

Minister Bruton Announces Expansion of Amgen Biotech Experience

Over 13,500 secondary school students are to benefit from a biotechnology hands-on lab experience over the next three years, after the Amgen Foundation announced an expansion of its Amgen Biotech Experience (ABE) progamme in partnership with University College Dublin (UCD) and Dublin City University

15 May, 2018 Read More

SBI Wins Research Lab of the Year 2018

Systems Biology Ireland won "Research Laboratory of the Year" recently at the Irish Laboratory Awards 2018.

25 April, 2018 Read More

Leukaemia Researcher Jonathan Bond Joins SBI as UCD 'Brendan McGonnell' Professor of Paediatric Molecular Haemato-Oncology

Professor Jonathan Bond has recently started at SBI as the UCD Brendan Mc Gonnell Professor of Paediatric Molecular Haemato-Oncology.

05 April, 2018 Read More

SBI Researchers Present New Research at Irish Association of Cancer Research (IACR) Conference 2018

The 54th IACR conference in Dublin in February 2018 saw a gathering of the frontiers of cancer research both from Ireland and internationally. SBI was strongly represented by researchers of various career stages...

03 April, 2018 Read More

Systems Biology Ireland to Bring the Power of Systems Medicine to Colorectal Cancer Patients

Researchers from Systems Biology Ireland (SBI) are participating in a €6 million international study called ‘COLOSSUS’ to harness the power of systems biomedicine, network analysis and mathematical modelling to improve treatments for colorectal cancer patients.

30 March, 2018 Read More

President Higgins Honours SFI President of Ireland Future Research Leaders Awardees

President of Ireland, Michael D. Higgins, honoured the recipients of the SFI President of Ireland Future Research Leaders Award, including SBI's Dr. Christina Kiel, at a special ceremony in Áras an Uachtaráin in Dublin recently.

07 February, 2018 Read More

eCancer Interview with Walter Kolch from EAPM 2017 Conference

SBI Director Walter Kolch recently spoke with eCancer while attending the European Alliance for Personalised Medicine Congress in Belfast.

05 January, 2018 Read More

UCD Breast Health Day 2017

Tuesday 24th October marked the third annual UCD Breast Health Day. The event was organized by SBI with help from colleagues from UCD Conway Institute, BREAST-PREDICT, UCD Nutrition Society, One Health UCD, UCD PharmTox Society and Europa Donna Ireland.

05 December, 2017 Read More

Uncovering How the Machinery of Life is Rewired in Breast Cancer

In our latest study we examined how the activity of these protein complexes is altered in breast cancer and in particular how the mutations that occur in breast cancers might influence how these molecular machines function.

06 November, 2017 Read More

Interpreting Genomes and Genome Functions: SBI-EMBL Scientific Meeting 2017

Systems Biology Ireland was delighted to welcome colleagues from the European Molecular Biology Laboratory (EMBL), Europe's flagship laboratory for the life sciences, to a joint scientific meeting on ‘Interpreting Genomes and Genome Functions’, 11-12 September 2017.

14 September, 2017 Read More

Awards Success for SBI

A busy day at two awards ceremonies at the Ballsbridge Hotel in Dublin saw SBI receive recognition for its education, outreach and collaborative activities.

26 May, 2017 Read More

Teacher Recognition Awards for Bringing Amgen Biotech Experience Into the Classroom

Two teachers from secondary schools in Dublin and Donegal have received teacher recognition awards at a ceremony in University College Dublin for their involvement in a science education initiative, the Amgen Biotech Experience.

11 May, 2017 Read More

Improving Cancer Treatment Using Machine Learning and Big Data Analysis

One in ten women in Ireland will develop breast cancer at some stage of their lives. In a recent project, we focused on Lapatinib, a commonly used drug for treating breast cancer.

09 May, 2017 Read More

Why March for Science?

The March for Science took place on the 22nd April, 2017, in over 600 cities around the world. SBI's Dirk Fey talks about what the day meant to those marching in Dublin.

28 April, 2017 Read More

Patient Voice in Cancer Research III

More than 100 cancer survivors and their families joined health care professionals, researchers, patient advocates, funding agencies and charity groups at an open forum in UCD on April 12th organised by SBI, Conway Institute and BREAST-PREDICT.

13 April, 2017 Read More

SBI Welcomes Two New Marie Sklodowska Curie Fellows

SBI is pleased to announce the awarding of prestigious Marie Sklodowska-Curie Fellowships to Dr Ariane Watson and Dr Oleksii Rukhlenko. These highly competitive awards support experienced researchers in their research training and career development.

21 April, 2017 Read More

St. Patrick's Festival -- A Multi-Coloured Scientific Experience

The Amgen Biotech Experience team from SBI joined the vibrant street carnival of Dublin's St Patrick's Festival Big Day Out on 17 March 2017, alongside street theatre, music, aerial performances, workshops, crafts and Irish language.

19 March, 2017 Read More

SBI at the Irish Association for Cancer Research Meeting

A group from SBI attended the 2017 Irish Association for Cancer Research (IACR) meeting in Kilkenny.

27 February, 2017 Read More

Developing Predictive Models of a Complex System Without Fully Knowing Its Inner Mechanisms

Complex systems emerge from dynamic interactions of many entities which influence each others' activities. In living cells thousands of genes and proteins interact with each other in a space, time and context dependent manner. A complete blueprint of these interactions are often unavailable.

05 December, 2016 Read More

SBI Hosts Ireland's First EMBO Leadership Workshop

SBI was delighted to co-organise a three-day 'Art of Leadership' workshop with UCD HR Learning & Development and in conjunction with the European Molecular Biology Organization(EMBO).

21 November, 2016 Read More

Pioneering Systems Biologist Awarded UCD Ulysses Medal

University College Dublin’s highest honour, the UCD Ulysses Medal has been bestowed on Dr Lee Hood in recognition of his outstanding contributions to science. UCD Deputy President and Registrar, Professor Mark Rogers presented the award at the 2016 UCD Conway Festival of Research & Innovation.

15 September, 2016 Read More

SBI Director Walter Kolch Elected to Royal Irish Academy

In recognition of his outstanding achievements in science, Professor Walter Kolch, Director of Systems Biology Ireland, has been elected to the ranks of the Royal Irish Academy. Election to membership of the Royal Irish Academy is the highest academic honour in Ireland.

30 May, 2016 Read More

Genetic Screening of Cancer Cell Lines to Identify New Targeted Treatments

One of the goals of personalised cancer therapeutics is to develop approaches that specifically kill tumour cells without harming healthy cells. A feature of tumour cells that we can exploit is the changes in their DNA that distinguish them from healthy cells.

23 May, 2016 Read More

US Cancer 'Moonshot' Initiative: A Cancer Scientist's Perspective

In this short video, SBI research fellow Dirk Fey discusses the new US cancer 'moonshot', an initiative announced by Barack Obama in his State of the Union address in January 2016.

21 January, 2016 Read More

2 + 4 = 6 , 4 + 2 = 7?

Researchers at UCD have recently found that order matters a surprising amount for sequence alignment, an important part of modern genetic analyses.

25 November, 2015 Read More
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