Overcoming resistance of RAS-mutant cells to RAF inhibitors by combining structurally different inhibitors can open new strides in targeted therapy.
Wednesday, 25 July, 2018
Tuesday, 17 July, 2018
Recently published research from Bond group in collaboration with Our Lady’s Children’s Hospital Crumlin
Monday, 06 November, 2017
Recently published research from Ryan group in collaboration with the Institute of Cancer Research, London
Tuesday, 09 May, 2017
New research published by the Santra Group in PLoS One
Wednesday, 25 November, 2015
What if the order you performed addition in mattered and the sum "2 + 3 + 4" gave you a different answer to the sum "4 + 3 + 2"? Researchers at UCD have recently found that order matters a surprising amount for sequence alignment, an important part of modern genetic analyses.
Monday, 05 December, 2016
New publication in Science Signalling reconstructs a predictive model using partial knowledge and experimentally observed behaviour of the pathway components.
Monday, 23 May, 2016
New research from SBI's and collaborators at the Institute of Cancer Research in London using genetic screening to identify genes that different cancer cell lines depend upon for survival.
Friday, 11 March, 2016
New research elucidates role of hydroxylases in regulating signalling pathway
Thursday, 07 January, 2016
New research just published by a team led by scientists from SBI has shown for the first time a computationally derived cancer biomarker outperforming classical biomarkers.
Thursday, 10 December, 2015
New research from SBI and collaborators in Basel and Seoul has found that cell fate can be determined by pulsed application of EGF hormone.
Monday, 27 July, 2015
New publication produced by SBI, funded through the EU FP7 Infrastructure for Systems Biology Europe project
Tuesday, 19 November, 2013
Researchers in UCD Conway Institute and Systems Biology Ireland have identified a way that a new class of anti-inflammatory drugs may be used to treat inflammatory bowel disease (IBD).
Tuesday, 17 June, 2014
Findings published in PLoS One will help scientists choose the best strategy to prepare data for statistical analysis
Monday, 23 June, 2014
New research shows opposing biological functions are regulated by the same elements within a protein signalling network
Tuesday, 01 July, 2014
Prof. Higgins is one of only eleven researchers based at Irish universities to feature on the list which is a compilation of highly cited influential names in science.
How protein protection mechanisms aid breast cancer cell migration and other stories from our latest publications
Monday, 06 October, 2014
Read about SBI research on the mechanisms that affect cancer therapy efficacy as well as a round up of our recent publications.
Wednesday, 08 October, 2014
New research from SBI published in Nature Cell Biology shows opposing biological functions are regulated by the same elements within a protein signalling network.
Friday, 31 October, 2014
Nature have announced the top 100 most cited papers of all time, and papers authored by Des Higgins feature twice.
SBI principal investigator Prof. Cormac Taylor receives prestigious Nature accolade for inspiring science students
Tuesday, 04 November, 2014
2014 Nature Award for Mentoring in Science presented at Science Foundation Ireland’s 2014 Summit.
Thursday, 18 December, 2014
Round up of our latest publications, including a feature on a collaboration between researchers at UCD Conway Institute and SBI to use nanoparticles to target tumour cells.
New SBI research on breast cancer’s underlying molecular mechanisms, and more from our latest publications
Thursday, 19 March, 2015
SBI researchers and collaborators explore signalling and metabolic pathways that trigger phenotypic changes in breast cancer cells in response to external cues.