Publications per DCRC PI

2021 (to April) and 2020

Neil Docherty

  • Cohen RV, Pereira TV, Aboud CM, Petry TBZ, Lopes Correa JL, Schiavon CA, Pompílio CE, Pechy FNQ, da Costa Silva ACC, de Melo FLG, Cunha da Silveira LP, de Paris Caravatto PP, Halpern H, Monteiro FLJ, da Costa Martins B, Kuga R, Palumbo TMS, Docherty NG, le Roux CW. Effect of Gastric Bypass vs Best Medical Treatment on Early-Stage Chronic Kidney Disease in Patients With Type 2 Diabetes and Obesity: A Randomized Clinical Trial. JAMA Surg. 2020 Jun 3;155(8):e200420. doi: 10.1001/jamasurg.2020.0420. Epub ahead of print. PMID: 32492126; PMCID: PMC7270872.
  • Martin WP, le Roux CW, Docherty NG. Impact of Metabolic Surgery on Renal Injury in Pre-Clinical Models of Diabetic Kidney Disease. Nephron. 2020 Dec 2:1-10. doi: 10.1159/000511790. Epub ahead of print. PMID: 33264793.
  • Moffett RC, Docherty NG, le Roux CW. The altered enteroendocrine repertoire following roux-en-Y-gastric bypass as an effector of weight loss and improved glycaemic control. Appetite. 2021 Jan 1;156:104807. doi: 10.1016/j.appet.2020.104807. Epub 2020 Aug 29. PMID: 32871202.
  • Docherty NG, le Roux CW. Bariatric surgery for the treatment of chronic kidney disease in obesity and type 2 diabetes mellitus. Nat Rev Nephrol. 2020 Dec;16(12):709-720. doi: 10.1038/s41581-020-0323-4. Epub 2020 Aug 10. PMID: 32778788.
  • Martin WP, White J, López-Hernández FJ, Docherty NG, le Roux CW. Metabolic Surgery to Treat Obesity in Diabetic Kidney Disease, Chronic Kidney Disease, and End-Stage Kidney Disease; What Are the Unanswered Questions? Front Endocrinol (Lausanne). 2020 Aug 17;11:289. doi: 10.3389/fendo.2020.00289. PMID: 33013677; PMCID: PMC7462008.
  • Wilkinson M, Sinclair P, Dellatorre-Teixeira L, Swan P, Brennan E, Moran B, Wedekind D, Downey P, Sheahan K, Conroy E, Gallagher WM, Docherty N, Roux CL, Brennan DJ. The Molecular Effects of a High Fat Diet on Endometrial Tumour Biology. Life (Basel). 2020 Sep 10;10(9):188. doi: 10.3390/life10090188. PMID: 32927694; PMCID: PMC7554710.
  • Canney AL, Cohen RV, Elliott JA, M Aboud C, Martin WP, Docherty NG, le Roux CW. Improvements in diabetic albuminuria and podocyte differentiation following Roux-en-Y gastric bypass surgery. Diab Vasc Dis Res. 2020 Jan-Feb;17(1):1479164119879039. doi: 10.1177/1479164119879039. Epub 2019 Nov 14. PMID: 31726864; PMCID: PMC7510366.
  • Silveira FC, Docherty NG, Sallet PC, Moraes M, Monclaro T, Arruda E Silva M, Pizani CE, Sallet JA, le Roux CW. Early Post-operative Weight Change After Roux-en-Y Gastric Bypass Predicts Weight Loss at 12-Month Follow-up. Obes Surg. 2020 Dec;30(12):5020-5025. doi: 10.1007/s11695-020-04942-1. Epub 2020 Aug 28. PMID: 32857300.
  • Nair M, Martin WP, Zhernovkov V, Elliott JA, Fearon N, Eckhardt H, McCormack J, Godson C, Brennan EP, Fandriks L, Docherty NG, le Roux CW. Characterization of the renal cortical transcriptome following Roux-en-Y gastric bypass surgery in experimental diabetic kidney disease. BMJ Open Diabetes Res Care. 2020 Jul;8(1):e001113. doi: 10.1136/bmjdrc-2019-001113. Erratum in: BMJ Open Diabetes Res Care. 2020 Aug;8(1): PMID: 32747384; PMCID: PMC7398104.
  • Sancho-Martínez SM, Blanco-Gozalo V, Quiros Y, Prieto-García L, Montero- Gómez MJ, Docherty NG, Martínez-Salgado C, Morales AI, López-Novoa JM, López-Hernández FJ. Impaired Tubular Reabsorption Is the Main Mechanism Explaining Increases in Urinary NGAL Excretion Following Acute Kidney Injury in Rats. Toxicol Sci. 2020 May 1;175(1):75-86. doi: 10.1093/toxsci/kfaa029. PMID: 32110797.
  • Wallenius V, Elias E, Elebring E, Haisma B, Casselbrant A, Larraufie P, Spak E, Reimann F, le Roux CW, Docherty NG, Gribble FM, Fändriks L. Suppression of enteroendocrine cell glucagon-like peptide (GLP)-1 release by fat-induced small intestinal ketogenesis: a mechanism targeted by Roux-en-Y gastric bypass surgery but not by preoperative very-low-calorie diet. Gut. 2020 Aug;69(8):1423-1431. doi: 10.1136/gutjnl-2019-319372. Epub 2019 Nov 21. PMID: 31753852; PMCID: PMC7347417.
  • Martin WP, Bauer J, Coleman J, Dellatorre-Teixeira L, Reeve JLV, Twomey PJ, Docherty NG, O'Riordan A, Watson AJ, le Roux CW, Holian J. Obesity is common in chronic kidney disease and associates with greater antihypertensive usage and proteinuria: evidence from a cross-sectional study in a tertiary nephrology centre. Clin Obes. 2020 Dec;10(6):e12402. doi: 10.1111/cob.12402. Epub 2020 Aug 26. PMID: 32845571; PMCID: PMC7685118.
  • Martin WP, Tuohy C, Doody A, Jackson S, Canavan RJ, Slattery D, Twomey PJ, McKenna MJ, le Roux CW, Docherty NG. Parallel assessment of albuminuria and plasma sTNFR1 in people with type 2 diabetes and advanced chronic kidney disease provides accurate prognostication of the risks of renal decline and death. Sci Rep. 2020 Sep 9;10(1):14852. doi: 10.1038/s41598-020-71684-6. PMID: 32908199; PMCID: PMC7481247.
  • Murphy CF, Fanning M, Raftery N, Elliott JA, Docherty NG, Donohoe CL, Ravi N, le Roux CW, Reynolds JV. Early experience with a nutrition and survivorship clinic in esophageal cancer. Dis Esophagus. 2021 Feb 10;34(2):doaa061. doi: 10.1093/dote/doaa061. PMID: 32566939.
  • Murphy CF, Stratford N, Docherty NG, Moran B, Elliott JA, Healy ML, McMorrow JP, Ravi N, Goldstone AP, Reynolds JV, le Roux CW. A Pilot Study of Gut-Brain Signaling After Octreotide Therapy for Unintentional Weight Loss After Esophagectomy. J Clin Endocrinol Metab. 2021 Jan 1;106(1):e204-e216. doi: 10.1210/clinem/dgaa697. PMID: 33000149.

Catherine Godson

  • Serhan CN, Gupta SK, Perretti M, Godson C, Brennan E, Li Y, Soehnlein O, Shimizu T, Werz O, Chiurchiù V, Azzi A, Dubourdeau M, Gupta SS, Schopohl P, Hoch M, Gjorgevikj D, Khan FM, Brauer D, Tripathi A, Cesnulevicius K, Lescheid D, Schultz M, Särndahl E, Repsilber D, Kruse R, Sala A, Haeggström JZ, Levy BD, Filep JG, Wolkenhauer O. The Atlas of Inflammation Resolution (AIR). Mol Aspects Med. 2020 Aug;74:100894. doi: 10.1016/j.mam.2020.100894. Epub 2020 Sep 3. PMID: 32893032; PMCID: PMC7733955.
  • Godson C. Balancing the Effect of Leukotrienes in Asthma. N Engl J Med. 2020 Apr 9;382(15):1472-1475. doi: 10.1056/NEJMcibr2000118. PMID: 32268033.
  • Doyle R, Godson C, Brennan E. Promoting resolution in kidney disease: are we nearly there yet? Curr Opin Nephrol Hypertens. 2020 Jan;29(1):119-127. doi: 10.1097/MNH.0000000000000558. PMID: 31599748.
  • Perretti M, Godson C. Formyl peptide receptor type 2 agonists to kick-start resolution pharmacology. Br J Pharmacol. 2020 Oct;177(20):4595-4600. doi: 10.1111/bph.15212. Epub 2020 Sep 20. PMID: 32954491; PMCID: PMC7520433.
  • Fu T, Mohan M, Brennan EP, Woodman OL, Godson C, Kantharidis P, Ritchie RH, Qin CX. Therapeutic Potential of Lipoxin A<sub>4</sub> in Chronic Inflammation: Focus on Cardiometabolic Disease. ACS Pharmacol Transl Sci. 2020 Jan 17;3(1):43-55. doi: 10.1021/acsptsci.9b00097. PMID: 32259087; PMCID: PMC7088989.
  • Benson KA, Murray SL, Doyle R, Doyle B, Dorman AM, Sadlier D, Brennan E, Large M, Cavalleri GL, Godson C, Conlon PJ. Diagnostic utility of genetic testing in patients undergoing renal biopsy. Cold Spring Harb Mol Case Stud. 2020 Oct 7;6(5):a005462. doi: 10.1101/mcs.a005462. PMID: 32723786; PMCID: PMC7552929.
  • Nair M, Martin WP, Zhernovkov V, Elliott JA, Fearon N, Eckhardt H, McCormack J, Godson C, Brennan EP, Fandriks L, Docherty NG, le Roux CW. Characterization of the renal cortical transcriptome following Roux-en-Y gastric bypass surgery in experimental diabetic kidney disease. BMJ Open Diabetes Res Care. 2020 Jul;8(1):e001113. doi: 10.1136/bmjdrc-2019-001113. Erratum in: BMJ Open Diabetes Res Care. 2020 Aug;8(1): PMID: 32747384; PMCID: PMC7398104.
  • Maciuszek M, Cacace A, Brennan E, Godson C, Chapman TM. Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential. Eur J Med Chem. 2021 Mar 5;213:113167. doi: 10.1016/j.ejmech.2021.113167. Epub 2021 Jan 12. PMID: 33486199.
  • Andrews D, Godson C. Lipoxins and synthetic lipoxin mimetics: therapeutic potential in renal diseases. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Apr 8:158940. doi: 10.1016/j.bbalip.2021.158940. Epub ahead of print. PMID: 33839296.

Fiona McGillicuddy

  • Curley S, Gall J, Byrne R, Yvan-Charvet L, McGillicuddy FC. Metabolic Inflammation in Obesity-At the Crossroads between Fatty Acid and Cholesterol Metabolism. Mol Nutr Food Res. 2021 Jan;65(1):e1900482. doi: 10.1002/mnfr.201900482. Epub 2020 Aug 20. PMID: 32754976.
  • Ralston JC, Nguyen-Tu MS, Lyons CL, Cooke AA, Murphy AM, Falvey A, Finucane OM, McGillicuddy FC, Rutter GA, Roche HM. Dietary substitution of SFA with MUFA within high-fat diets attenuates hyperinsulinaemia and pancreatic islet dysfunction. Br J Nutr. 2020 Aug 14;124(3):247-255. doi: 10.1017/S0007114520000859. Epub 2020 Mar 3. PMID: 32122411.
  • Ahmed MO, Byrne RE, Pazderska A, Segurado R, Guo W, Gunness A, Frizelle I, Sherlock M, Ahmed KS, McGowan A, Moore K, Boran G, McGillicuddy FC, Gibney J. HDL particle size is increased and HDL-cholesterol efflux is enhanced in type 1 diabetes: a cross-sectional study. Diabetologia. 2021 Mar;64(3):656-667. doi: 10.1007/s00125-020-05320-3. Epub 2020 Nov 9. PMID: 33169205.
  • O'Reilly ME, Lenighan YM, Dillon E, Kajani S, Curley S, Bruen R, Byrne R, Heslin AM, Moloney AP, Roche HM, McGillicuddy FC. Conjugated Linoleic Acid and Alpha Linolenic Acid Improve Cholesterol Homeostasis in Obesity by Modulating Distinct Hepatic Protein Pathways. Mol Nutr Food Res. 2020 Apr;64(7):e1900599. doi: 10.1002/mnfr.201900599. Epub 2020 Jan 22. PMID: 31917888.
  • Ralston JC, Mitchelson KAJ, Lynch GM, Tran TTT, Wang H, Strain CR, Lenighan YM, Kennedy EB, Stanton C, McGillicuddy FC, Su Q, O'Toole PW, Roche HM. Microbiome Transfer Partly Overrides Lack of IL-1RI Signaling to Alter Hepatic but not Adipose Tissue Phenotype and Lipid Handling following a High-Fat Diet Challenge. Mol Nutr Food Res. 2021 Jan;65(1):e2000202. doi: 10.1002/mnfr.202000202. Epub 2020 Jul 12. PMID: 32558187.

Carel le Roux

  • le Roux CW. Biography: Carel le Roux. Obes Surg. 2020 Jun;30(6):2074-2075. doi: 10.1007/s11695-020-04618-w. PMID: 32314254. Rubino F, Puhl RM, Cummings DE, Eckel RH, Ryan DH, Mechanick JI, Nadglowski J, Ramos Salas X, Schauer PR, Twenefour D, Apovian CM, Aronne LJ, Batterham RL,
  • Berthoud HR, Boza C, Busetto L, Dicker D, De Groot M, Eisenberg D, Flint SW, Huang TT, Kaplan LM, Kirwan JP, Korner J, Kyle TK, Laferrère B, le Roux CW, McIver L, Mingrone G, Nece P, Reid TJ, Rogers AM, Rosenbaum M, Seeley RJ, Torres AJ, Dixon JB. Joint international consensus statement for ending stigma of obesity. Nat Med. 2020 Apr;26(4):485-497. doi: 10.1038/s41591-020-0803-x. Epub 2020 Mar 4. PMID: 32127716; PMCID: PMC7154011.
  • Kwok S, Adam S, Ho JH, Iqbal Z, Turkington P, Razvi S, Le Roux CW, Soran H, Syed AA. Obesity: A critical risk factor in the COVID-19 pandemic. Clin Obes. 2020 Dec;10(6):e12403. doi: 10.1111/cob.12403. Epub 2020 Aug 28. PMID: 32857454; PMCID: PMC7460880.
  • Rubino F, Cohen RV, Mingrone G, le Roux CW, Mechanick JI, Arterburn DE, Vidal J, Alberti G, Amiel SA, Batterham RL, Bornstein S, Chamseddine G, Del Prato S, Dixon JB, Eckel RH, Hopkins D, McGowan BM, Pan A, Patel A, Pattou F, Schauer PR, Zimmet PZ, Cummings DE. Bariatric and metabolic surgery during and after the COVID-19 pandemic: DSS recommendations for management of surgical candidates and postoperative patients and prioritisation of access to surgery. Lancet Diabetes Endocrinol. 2020 Jul;8(7):640-648. doi: 10.1016/S2213-8587(20)30157-1. Epub 2020 May 7. PMID: 32386567; PMCID: PMC7252156.
  • Cohen RV, Pereira TV, Aboud CM, Petry TBZ, Lopes Correa JL, Schiavon CA, Pompílio CE, Pechy FNQ, da Costa Silva ACC, de Melo FLG, Cunha da Silveira LP,de Paris Caravatto PP, Halpern H, Monteiro FLJ, da Costa Martins B, Kuga R, Palumbo TMS, Docherty NG, le Roux CW. Effect of Gastric Bypass vs Best Medical Treatment on Early-Stage Chronic Kidney Disease in Patients With Type 2 Diabetes and Obesity: A Randomized Clinical Trial. JAMA Surg. 2020 Jun 3;155(8):e200420. doi: 10.1001/jamasurg.2020.0420. Epub ahead of print. PMID: 32492126; PMCID: PMC7270872.
  • McCrimmon RJ, Catarig AM, Frias JP, Lausvig NL, le Roux CW, Thielke D, Lingvay I. Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised controlled clinical trial. Diabetologia. 2020 Mar;63(3):473-485. doi: 10.1007/s00125-019-05065-8. Epub 2020 Jan 2. PMID: 31897524; PMCID: PMC6997246.
  • Sudlow AC, le Roux CW. Why are adolescents with obesity and diabetes not having bariatric surgery earlier? Surg Obes Relat Dis. 2021 Jan;17(1):33-35. doi: 10.1016/j.soard.2020.10.005. Epub 2020 Oct 15. PMID: 33218902.
  • Sudlow A, le Roux CW, Pournaras DJ. The metabolic benefits of different bariatric operations: what procedure to choose? Endocr Connect. 2020 Feb;9(2):R28-R35. doi: 10.1530/EC-19-0467. PMID: 31917678; PMCID: PMC6993254.
  • Moffett RC, Docherty NG, le Roux CW. The altered enteroendocrine repertoire following roux-en-Y-gastric bypass as an effector of weight loss and improved glycaemic control. Appetite. 2021 Jan 1;156:104807. doi: 10.1016/j.appet.2020.104807. Epub 2020 Aug 29. PMID: 32871202.
  • Neff KJ, Le Roux CW. The Effect of Metabolic Surgery on the Complications of Diabetes: What Are the Unanswered Questions? Front Endocrinol (Lausanne). 2020 May 29;11:304. doi: 10.3389/fendo.2020.00304. PMID: 32547487; PMCID: PMC7272689.
  • Canney AL, Cohen RV, Elliott JA, M Aboud C, Martin WP, Docherty NG, le Roux CW. Improvements in diabetic albuminuria and podocyte differentiation following Roux-en-Y gastric bypass surgery. Diab Vasc Dis Res. 2020 Jan-Feb;17(1):1479164119879039. doi: 10.1177/1479164119879039. Epub 2019 Nov 14. PMID: 31726864; PMCID: PMC7510366.
  • Sultan S, Patel AG, El-Hassani S, Whitelaw B, Leca BM, Vincent RP, le Roux CW, Rubino F, Aywlin SJB, Dimitriadis GK. Male Obesity Associated Gonadal Dysfunction and the Role of Bariatric Surgery. Front Endocrinol (Lausanne). 2020 Jun 19;11:408. doi: 10.3389/fendo.2020.00408. PMID: 32636807; PMCID: PMC7318874.
  • Martin WP, le Roux CW. Comment on: Impact of serum uric acid on renal function after bariatric surgery: a retrospective study. Surg Obes Relat Dis. 2020 Feb;16(2):295-298. doi: 10.1016/j.soard.2019.11.002. Epub 2019 Nov 13. PMID: 31839528; PMCID: PMC7116486.
  • Sudlow AC, Le Roux CW, Pournaras DJ. Long-term outcomes of bariatric surgery in patients with diabetes. Expert Rev Endocrinol Metab. 2020 May;15(3):141-146. doi: 10.1080/17446651.2020.1754191. Epub 2020 Apr 15. PMID: 32292077.
  • Martin WP, le Roux CW, Docherty NG. Impact of Metabolic Surgery on Renal Injury in Pre-Clinical Models of Diabetic Kidney Disease. Nephron. 2020 Dec 2:1-10. doi: 10.1159/000511790. Epub ahead of print. PMID: 33264793.
  • Wilkinson M, Sinclair P, Dellatorre-Teixeira L, Swan P, Brennan E, Moran B, Wedekind D, Downey P, Sheahan K, Conroy E, Gallagher WM, Docherty N, Roux CL, Brennan DJ. The Molecular Effects of a High Fat Diet on Endometrial Tumour Biology. Life (Basel). 2020 Sep 10;10(9):188. doi: 10.3390/life10090188. PMID: 32927694; PMCID: PMC7554710.
  • le Roux CW, Hartvig NV, Haase CL, Nordsborg RB, Olsen AH, Satylganova A. Obesity, cardiovascular risk and healthcare resource utilization in the UK. Eur J Prev Cardiol. 2020 May 27:2047487320925639. doi: 10.1177/2047487320925639. Epub ahead of print. PMID: 32460533.
  • Docherty NG, le Roux CW. Bariatric surgery for the treatment of chronic kidney disease in obesity and type 2 diabetes mellitus. Nat Rev Nephrol. 2020 Dec;16(12):709-720. doi: 10.1038/s41581-020-0323-4. Epub 2020 Aug 10. PMID: 32778788.
  • Al-Ozairi E, El Samad A, Al Kandari J, Taghadom E, Adam S, le Roux C, Syed AA. Continuous Glucose Monitoring of Glycemic Variability During Fasting Post- Sleeve Gastrectomy. Obes Surg. 2020 Oct;30(10):3721-3729. doi: 10.1007/s11695-020-04505-4. PMID: 32676844; PMCID: PMC7467959.
  • Hankir MK, Langseder T, Bankoglu EE, Ghoreishi Y, Dischinger U, Kurlbaum M, Kroiss M, Otto C, le Roux CW, Arora T, Seyfried F, Schlegel N. Simulating the Post-gastric Bypass Intestinal Microenvironment Uncovers a Barrier-Stabilizing Role for FXR. iScience. 2020 Nov 5;23(12):101777. doi: 10.1016/j.isci.2020.101777. PMID: 33294786; PMCID: PMC7689555.
  • Martin WP, White J, López-Hernández FJ, Docherty NG, le Roux CW. Metabolic Surgery to Treat Obesity in Diabetic Kidney Disease, Chronic Kidney Disease, and End-Stage Kidney Disease; What Are the Unanswered Questions? Front Endocrinol (Lausanne). 2020 Aug 17;11:289. doi: 10.3389/fendo.2020.00289. PMID: 33013677; PMCID: PMC7462008.
  • Gomide Braga T, das Graças Coelho de Souza M, Maranhão PA, Menezes M, Dellatorre-Teixeira L, Bouskela E, Le Roux CW, Kraemer-Aguiar LG. Evaluation of Heart Rate Variability and Endothelial Function 3 Months After Bariatric Surgery. Obes Surg. 2020 Jun;30(6):2450-2453. doi: 10.1007/s11695-020-04397-4. PMID: 31916132.
  • Martin WP, le Roux CW. Can Metabolic Surgery Be Used to Improve Access to and Outcomes of Kidney Transplantation? Obesity (Silver Spring). 2020 Dec;28(12):2259. doi: 10.1002/oby.23052. PMID: 33230960; PMCID: PMC7116467.
  • Silveira FC, Docherty NG, Sallet PC, Moraes M, Monclaro T, Arruda E Silva M, Pizani CE, Sallet JA, le Roux CW. Early Post-operative Weight Change After Roux- en-Y Gastric Bypass Predicts Weight Loss at 12-Month Follow-up. Obes Surg. 2020 Dec;30(12):5020-5025. doi: 10.1007/s11695-020-04942-1. Epub 2020 Aug 28. PMID: 32857300.
  • le Roux CW, Ottosson J, Näslund E, Cohen RV, Stenberg E, Sundbom M, Näslund I. Bariatric Surgery: There Is a Room for Improvement to Reduce Mortality in Patients with Type 2 Diabetes. Obes Surg. 2021 Jan;31(1):461-463. doi: 10.1007/s11695-020-04934-1. Epub 2020 Aug 26. PMID: 32845478.
  • Grannell A, Fallon F, Pournaras D, le Roux CW. Exploring patient beliefs and perceptions regarding obesity as a disease, obesity causation and treatment. Ir J Med Sci. 2021 Feb;190(1):163-168. doi: 10.1007/s11845-020-02319-y. Epub 2020 Jul 21. PMID: 32696243.
  • Duggan SN, O'Connor DB, Antanaitis A, Campion JR, Lawal O, Ahmed M, Tisdall AR, Sherlock M, Boran G, le Roux C, Gibney J, Conlon KC. Metabolic dysfunction and diabetes mellitus during long-term follow-up of severe acute pancreatitis: A case-matched study. Pancreatology. 2020 Jul;20(5):813-821. doi: 10.1016/j.pan.2020.03.016. Epub 2020 Jun 4. PMID: 32522508.
  • Nielsen MS, Ritz C, Wewer Albrechtsen NJ, Holst JJ, le Roux CW, Sjödin A. Oxyntomodulin and Glicentin May Predict the Effect of Bariatric Surgery on Food Preferences and Weight Loss. J Clin Endocrinol Metab. 2020 Apr 1;105(4):dgaa061. doi: 10.1210/clinem/dgaa061. PMID: 32016415.
  • Grannell A, le Roux CW, McGillicuddy D. "I am terrified of something happening to me" The lived experience of people with obesity during the COVID-19 pandemic. Clin Obes. 2020 Dec;10(6):e12406. doi: 10.1111/cob.12406. Epub 2020 Sep 4. PMID: 32885595.
  • Nair M, Martin WP, Zhernovkov V, Elliott JA, Fearon N, Eckhardt H, McCormack J, Godson C, Brennan EP, Fandriks L, Docherty NG, le Roux CW. Characterization of the renal cortical transcriptome following Roux-en-Y gastric bypass surgery in experimental diabetic kidney disease. BMJ Open Diabetes Res Care. 2020 Jul;8(1):e001113. doi: 10.1136/bmjdrc-2019-001113. Erratum in: BMJ Open Diabetes Res Care. 2020 Aug;8(1): PMID: 32747384; PMCID: PMC7398104.
  • Wallenius V, Elias E, Elebring E, Haisma B, Casselbrant A, Larraufie P, Spak E, Reimann F, le Roux CW, Docherty NG, Gribble FM, Fändriks L. Suppression of enteroendocrine cell glucagon-like peptide (GLP)-1 release by fat-induced small intestinal ketogenesis: a mechanism targeted by Roux-en-Y gastric bypass surgery but not by preoperative very-low-calorie diet. Gut. 2020 Aug;69(8):1423-1431. doi: 10.1136/gutjnl-2019-319372. Epub 2019 Nov 21. PMID: 31753852; PMCID: PMC7347417
  • Braga TG, Graças Coelho de Souza MD, Menezes M, Nogueira Neto JF, Dellatorre-Teixeira L, Bouskela E, le Roux CW, Kraemer-Aguiar LG. Dipeptidyl peptidase-4 activity, lipopolysaccharide, C-reactive protein, glucose metabolism, and gut peptides 3 months after bariatric surgery. Surg Obes Relat Dis. 2021 Jan;17(1):113-120. doi: 10.1016/j.soard.2020.08.030. Epub 2020 Sep 1. PMID: 33036944.
  • Kashyap SR, Kheniser K, Aminian A, Schauer P, Le Roux C, Burguera B. Double-nblinded, randomized, and controlled study on the effects of canagliflozin after bariatric surgery: A pilot study. Obes Sci Pract. 2020 Mar 17;6(3):255-263. doi: 10.1002/osp4.409. PMID: 32523714; PMCID: PMC7278903.
  • Minnock D, Annibalini G, Le Roux CW, Contarelli S, Krause M, Saltarelli R, Valli G, Stocchi V, Barbieri E, De Vito G. Effects of acute aerobic, resistance and combined exercises on 24-h glucose variability and skeletal muscle signalling responses in type 1 diabetics. Eur J Appl Physiol. 2020 Dec;120(12):2677-2691. doi: 10.1007/s00421-020-04491-6. Epub 2020 Sep 9. PMID: 32909059.
  • Papamargaritis D, Al-Najim W, Lim J, Crane J, Lean M, le Roux C, McGowan B, O'Shea D, Webb D, Wilding J, Davies MJ. Effectiveness and cost of integrating a pragmatic pathway for prescribing liraglutide 3.0 mg in obesity services (STRIVE study): study protocol of an open-label, real-world, randomised, controlled trial. BMJ Open. 2020 Feb 13;10(2):e034137. doi: 10.1136/bmjopen-2019-034137. PMID: 32060156; PMCID: PMC7044994.
  • Sjöholm K, Carlsson LMS, Taube M, le Roux CW, Svensson PA, Peltonen M. Comparison of Preoperative Remission Scores and Diabetes Duration Alone as Predictors of Durable Type 2 Diabetes Remission and Risk of Diabetes Complications After Bariatric Surgery: A Post Hoc Analysis of Participants From the Swedish Obese Subjects Study. Diabetes Care. 2020 Nov;43(11):2804-2811. doi: 10.2337/dc20- 157. Epub 2020 Sep 1. PMID: 32873586; PMCID: PMC7576422.
  • Martin WP, Bauer J, Coleman J, Dellatorre-Teixeira L, Reeve JLV, Twomey PJ, Docherty NG, O'Riordan A, Watson AJ, le Roux CW, Holian J. Obesity is common in chronic kidney disease and associates with greater antihypertensive usage and proteinuria: evidence from a cross-sectional study in a tertiary nephrology centre. Clin Obes. 2020 Dec;10(6):e12402. doi: 10.1111/cob.12402. Epub 2020 Aug 26. PMID: 32845571; PMCID: PMC7685118.
  • Nielsen MS, Christensen BJ, Schmidt JB, Tækker L, Holm L, Lunn S, Ritz C, Wewer Albrechtsen NJ, Holst JJ, Schnurr TM, Hansen T, le Roux CW, Lund TB, Floyd AK, Sjödin A. Predictors of weight loss after bariatric surgery-a cross- disciplinary approach combining physiological, social, and psychological measures. Int J Obes (Lond). 2020 Nov;44(11):2291-2302. doi: 10.1038/s41366-020-0576-9. Epub 2020 Apr 23. PMID: 32327722.
  • Martin WP, Tuohy C, Doody A, Jackson S, Canavan RJ, Slattery D, Twomey PJ, McKenna MJ, le Roux CW, Docherty NG. Parallel assessment of albuminuria and plasma sTNFR1 in people with type 2 diabetes and advanced chronic kidney disease rovides accurate prognostication of the risks of renal decline and death. Sci Rep. 2020 Sep 9;10(1):14852. doi: 10.1038/s41598-020-71684-6. PMID: 32908199; PMCID: PMC7481247.
  • Hyde KM, Blonde GD, Bueter M, le Roux CW, Spector AC. Gastric bypass in female rats lowers concentrated sugar solution intake and preference without affecting brief-access licking after long-term sugar exposure. Am J Physiol Regul Integr Comp Physiol. 2020 May 1;318(5):R870-R885. doi: 10.1152/ajpregu.00240.2019. Epub 2020 Feb 21. PMID: 32083966; PMCID: PMC7272762.
  • Miras AD, le Roux CW. Metabolic surgery versus conventional therapy in type 2 diabetes. Lancet. 2021 Jan 23;397(10271):256-257. doi: 10.1016/S0140-6736(21)00129-X. PMID: 33485432.
  • McGlone ER, Carey I, Veličković V, Chana P, Mahawar K, Batterham RL, Hopkins J, Walton P, Kinsman R, Byrne J, Somers S, Kerrigan D, Menon V, Borg C, Ahmed A, Sgromo B, Cheruvu C, Bano G, Leonard C, Thom H, le Roux CW, Reddy M, Welbourn R, Small P, Khan OA. Bariatric surgery for patients with type 2 diabetes mellitus requiring insulin: Clinical outcome and cost-effectiveness analyses. PLoS Med. 2020 Dec 7;17(12):e1003228. doi: 10.1371/journal.pmed.1003228. PMID: 33285553; PMCID: PMC7721482.
  • le Roux CW. COVID-19 alters thinking and management in metabolic diseases. Nat Rev Endocrinol. 2021 Feb;17(2):71-72. doi: 10.1038/s41574-020-00449-y. PMID: 33239662; PMCID: PMC7687210.
  • Alruwaili H, Dehestani B, le Roux CW. Clinical Impact of Liraglutide as a Treatment of Obesity. Clin Pharmacol. 2021 Mar 11;13:53-60. doi: 10.2147/CPAA.S276085. PMID: 33732030; PMCID: PMC7958997.
  • Friedman AN, Kaplan LM, le Roux CW, Schauer PR. Management of Obesity in Adults with CKD. J Am Soc Nephrol. 2021 Feb 18:ASN.2020101472. doi: 10.1681/ASN.2020101472. Epub ahead of print. MID: 33602674.
  • Murphy CF, Fanning M, Raftery N, Elliott JA, Docherty NG, Donohoe CL, Ravi N, le Roux CW, Reynolds JV. Early experience with a nutrition and survivorship clinic in esophageal cancer. Dis Esophagus. 2021 Feb 10;34(2):doaa061. doi: 10.1093/dote/doaa061. PMID: 32566939.
  • Cohen RV, Pereira TV, le Roux CW. The Role of Bariatric Surgery in Prevention of Kidney Disease Progression in Moderately Obese Patients With Type 2 Diabetes-Reply. JAMA Surg. 2021 Feb 1;156(2):206-207. doi: 10.1001/jamasurg.2020.5192. PMID: 33206165.
  • Murphy CF, Stratford N, Docherty NG, Moran B, Elliott JA, Healy ML, McMorrow JP, Ravi N, Goldstone AP, Reynolds JV, le Roux CW. A Pilot Study of Gut-Brain Signaling After Octreotide Therapy for Unintentional Weight Loss After Esophagectomy. J Clin Endocrinol Metab. 2021 Jan 1;106(1):e204-e216. doi: 10.1210/clinem/dgaa697. PMID: 33000149.
  • Redpath TL, Livingstone MBE, Dunne AA, Boyd A, le Roux CW, Spector AC, Price RK. Methodological issues in assessing change in dietary intake and appetite following gastric bypass surgery: A systematic review. Obes Rev. 2021 Feb 1. doi: 10.1111/obr.13202. Epub ahead of print. PMID: 33527664.
  • Papamargaritis D, le Roux CW. Do Gut Hormones Contribute to Weight Loss and Glycaemic Outcomes after Bariatric Surgery? Nutrients. 2021 Feb 26;13(3):762. doi: 10.3390/nu13030762. PMID: 33652862; PMCID: PMC7996890.
  • Grannell A, Martin WP, Dehestani B, Al-Najim W, Murphy JC, le Roux CW. Liraglutide Does Not Adversely Impact Fat-Free Mass Loss. Obesity (Silver Spring). 2021 Mar;29(3):529-534. doi: 10.1002/oby.23098. Epub 2021 Feb 2. PMID: 33528919.
  • Mohammed N, Buckley A, Elsheikh M, Allum M, Suliman S, Al Hadad M, le Roux CW, Lessan N, Suliman M. Bariatric surgery in the treatment of patients with obesity and type 1 diabetes: A retrospective study of clinical data. Diabetes Obes Metab. 2021 Mar 9. doi: 10.1111/dom.14369. Epub ahead of print. PMID: 33687753.
  • Nielsen MS, Christensen BJ, Ritz C, Holm L, Lunn S, Tækker L, Schmidt JB, Bredie WLP, Wewer Albrechtsen NJ, Holst JJ, Hilbert A, le Roux CW, Sjödin A. Factors Associated with Favorable Changes in Food Preferences After Bariatric Surgery. Obes Surg. 2021 Mar 30. doi: 10.1007/s11695-021-05374-1. Epub ahead of print. PMID: 33786744.
  • Wölnerhanssen BK, Drewe J, Verbeure W, le Roux CW, Dellatorre-Teixeira L, Rehfeld JF, Holst JJ, Hartmann B, Tack J, Peterli R, Beglinger C, Meyer-Gerspach AC. Gastric emptying of solutions containing the natural sweetener erythritol and effects on gut hormone secretion in humans: A pilot dose-ranging study. Diabetes Obes Metab. 2021 Feb 10. doi: 10.1111/dom.14342. Epub ahead of print. PMID: 33565706.

Helen Roche

  • De Marco Castro E, Calder PC, Roche HM. β-1,3/1,6-Glucans and Immunity: State of the Art and Future Directions. Mol Nutr Food Res. 2021 Jan;65(1):e1901071. doi: 10.1002/mnfr.201901071. Epub 2020 Apr 27. PMID: 32223047; PMCID: PMC7816268.
  • Gleeson LE, Roche HM, Sheedy FJ. Obesity, COVID-19 and innate immunometabolism. Br J Nutr. 2021 Mar 28;125(6):628-632. doi: 10.1017/S0007114520003529. Epub 2020 Sep 7. PMID: 32892755; PMCID: PMC7520638.
  • Charles-Messance H, Mitchelson KAJ, De Marco Castro E, Sheedy FJ, Roche HM. Regulating metabolic inflammation by nutritional modulation. J Allergy Clin Immunol. 2020 Oct;146(4):706-720. doi: 10.1016/j.jaci.2020.08.013. Epub 2020 Aug 22. PMID: 32841652.
  • Maruvada P, Lampe JW, Wishart DS, Barupal D, Chester DN, Dodd D, Djoumbou- Feunang Y, Dorrestein PC, Dragsted LO, Draper J, Duffy LC, Dwyer JT, Emenaker NJ, Fiehn O, Gerszten RE, B Hu F, Karp RW, Klurfeld DM, Laughlin MR, Little AR, Lynch CJ, Moore SC, Nicastro HL, O'Brien DM, Ordovás JM, Osganian SK, Playdon M, Prentice R, Raftery D, Reisdorph N, Roche HM, Ross SA, Sang S, Scalbert A,
  • Srinivas PR, Zeisel SH. Perspective: Dietary Biomarkers of Intake and Exposure- Exploration with Omics Approaches. Adv Nutr. 2020 Mar 1;11(2):200-215. doi: 10.1093/advances/nmz075. Erratum in: Adv Nutr. 2020 Mar 1;11(2):468. PMID: 31386148; PMCID: PMC7442414.
  • Roche HM. Metabolism and Inflammation: New Synergies and Insights. Mol Nutr Food Res. 2021 Jan;65(1):e2000994. doi: 10.1002/mnfr.202000994. PMID: 33421313.
  • Hillesheim E, Ryan MF, Gibney E, Roche HM, Brennan L. Optimisation of a metabotype approach to deliver targeted dietary advice. Nutr Metab (Lond). 2020 Sep 29;17:82. doi: 10.1186/s12986-020-00499-z. PMID: 33005208; PMCID: PMC7523294.
  • Hansen AMB, Wium C, Lee S, Tierney AC, McCarthy D, Roche HM, Drevon CA, Birkeland KI, Gulseth HL. Substantial inter-individual variations in insulin secretion and sensitivity across the glucometabolic spectrum. Scand J Clin Lab Invest. 2020 Jul;80(4):282-290. doi: 10.1080/00365513.2020.1730433. Epub 2020 Mar 5. PMID: 32134347.
  • Ralston JC, Nguyen-Tu MS, Lyons CL, Cooke AA, Murphy AM, Falvey A, Finucane OM, McGillicuddy FC, Rutter GA, Roche HM. Dietary substitution of SFA with MUFA within high-fat diets attenuates hyperinsulinaemia and pancreatic islet dysfunction. Br J Nutr. 2020 Aug 14;124(3):247-255. doi: 10.1017/S0007114520000859. Epub 2020 Mar 3. PMID: 32122411.
  • Fitzpatrick SF, King AD, O'Donnell C, Roche HM, Ryan S. Mechanisms of intermittent hypoxia-mediated macrophage activation - potential therapeutic targets for obstructive sleep apnoea. J Sleep Res. 2020 Sep 30:e13202. doi: 10.1111/jsr.13202. Epub ahead of print. PMID: 32996666.
  • Ralston JC, Mitchelson KAJ, Lynch GM, Tran TTT, Wang H, Strain CR, Lenighan YM, Kennedy EB, Stanton C, McGillicuddy FC, Su Q, O'Toole PW, Roche HM. Microbiome Transfer Partly Overrides Lack of IL-1RI Signaling to Alter Hepatic but not Adipose Tissue Phenotype and Lipid Handling following a High-Fat Diet Challenge. Mol Nutr Food Res. 2021 Jan;65(1):e2000202. doi: 10.1002/mnfr.202000202. Epub 2020 Jul 12. PMID: 32558187.
  • Lenighan YM, Nugent AP, Moloney AP, Monahan FJ, Walton J, Flynn A, Roche HM, McNulty BA. A modelling approach to investigate the impact of consumption of three different beef compositions on human dietary fat intakes. Public Health Nutr. 2020 Sep;23(13):2373-2383. doi: 10.1017/S1368980019003471. Epub 2019 Dec 12. PMID: 31829294.
  • O'Reilly ME, Lenighan YM, Dillon E, Kajani S, Curley S, Bruen R, Byrne R, Heslin AM, Moloney AP, Roche HM, McGillicuddy FC. Conjugated Linoleic Acid and Alpha Linolenic Acid Improve Cholesterol Homeostasis in Obesity by Modulating Distinct Hepatic Protein Pathways. Mol Nutr Food Res. 2020 Apr;64(7):e1900599. doi: 10.1002/mnfr.201900599. Epub 2020 Jan 22. PMID: 31917888.
  • Alligier M, Barrès R, Blaak EE, Boirie Y, Bouwman J, Brunault P, Campbell K, Clément K, Farooqi IS, Farpour-Lambert NJ, Frühbeck G, Goossens GH, Hager J, Halford JCG, Hauner H, Jacobi D, Julia C, Langin D, Natali A, Neovius M, Oppert JM, Pagotto U, Palmeira AL, Roche H, Rydén M, Scheen AJ, Simon C, Sorensen TIA, Tappy L, Yki-Järvinen H, Ziegler O, Laville M. OBEDIS Core Variables Project: European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions. Obes Facts. 2020;13(1):1-28. doi: 10.1159/000505342. Epub 2020 Jan 16. PMID: 31945762; PMCID: PMC7098277.
  • Lorenc A, Hamilton-Shield J, Perry R, Stevens M; CTYA HSCT Adipose and Muscle Late Effects Working Group. Body composition after allogeneic haematopoietic cell transplantation/total body irradiation in children and young people: a restricted systematic review. J Cancer Surviv. 2020 Oct;14(5):624-642. doi: 10.1007/s11764-020-00871-1. Epub 2020 Jul 18. PMID: 32388841; PMCID: PMC7473918.
  • Blaak EE, Roche HM, Afman LA. Editorial: Personalized Nutrition. Front Nutr. 2021 Mar 25;8:669307. doi: 10.3389/fnut.2021.669307. PMID: 33842527; PMCID: PMC8027071.
  • Burton-Pimentel KJ, Pimentel G, Hughes M, Michielsen CC, Fatima A, Vionnet N, Afman LA, Roche HM, Brennan L, Ibberson M, Vergères G. Discriminating Dietary Responses by Combining Transcriptomics and Metabolomics Data in Nutrition Intervention Studies. Mol Nutr Food Res. 2021 Feb;65(4):e2000647. doi: 10.1002/mnfr.202000647. Epub 2021 Jan 29. PMID: 33325641.
  • Ben-Harchache S, Roche HM, Corish CA, Horner KM. The Impact of Protein Supplementation on Appetite and Energy Intake in Healthy Older Adults: A Systematic Review with Meta-Analysis. Adv Nutr. 2021 Mar 31;12(2):490-502. doi: 10.1093/advances/nmaa115. PMID: 33037427.
  • Murphy CH, Flanagan EM, De Vito G, Susta D, Mitchelson KAJ, de Marco Castro E, Senden JMG, Goessens JPB, Mikłosz A, Chabowski A, Segurado R, Corish CA, McCarthy SN, Egan B, van Loon LJC, Roche HM. Does supplementation with leucine- enriched protein alone and in combination with fish-oil-derived n-3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? A randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2021 Apr 19:nqaa449. doi: 10.1093/ajcn/nqaa449. Epub ahead of print. PMID: 33871558.

Orina Belton

  • Fitzsimons S, Oggero S, Bruen R, McCarthy C, Strowitzki MJ, Mahon NG, Ryan N, Brennan EP, Barry M, Perretti M, Belton O. microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression. Front Immunol. 2020 Dec 17;11:576516. doi: 10.3389/fimmu.2020.576516. PMID: 33391256; PMCID: PMC7773661.
  • Oggero S, de Gaetano M, Marcone S, Fitzsimons S, Pinto AL, Ikramova D, Barry M, Burke D, Montero-Melendez T, Cooper D, Burgoyne T, Belton O, Norling LV, Brennan EP, Godson C, Perretti M. Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity. J Extracell Vesicles. 2021 Apr;10(6):12084. doi: 10.1002/jev2.12084. Epub 2021 Apr 27. PMID: 33936566; PMCID: PMC8077084.

John Crean

  • Monks P, Wychowaniec JK, McKiernan E, Clerkin S, Crean J, Rodriguez BJ, Reynaud EG, Heise A, Brougham DF. Spatiotemporally Resolved Heat Dissipation in 3D Patterned Magnetically Responsive Hydrogels. Small. 2021 Feb;17(5):e2004452. doi: 10.1002/smll.202004452. Epub 2020 Dec 28. PMID: 3369876.

Eoin Brennan

  • Serhan CN, Gupta SK, Perretti M, Godson C, Brennan E, Li Y, Soehnlein O, Shimizu T, Werz O, Chiurchiù V, Azzi A, Dubourdeau M, Gupta SS, Schopohl P, Hoch M, Gjorgevikj D, Khan FM, Brauer D, Tripathi A, Cesnulevicius K, Lescheid D, Schultz M, Särndahl E, Repsilber D, Kruse R, Sala A, Haeggström JZ, Levy BD, Filep JG, Wolkenhauer O. The Atlas of Inflammation Resolution (AIR). Mol Aspects Med. 2020 Aug;74:100894. doi: 10.1016/j.mam.2020.100894. Epub 2020 Sep 3. PMID: 32893032; PMCID:
  • Doyle R, Godson C, Brennan E. Promoting resolution in kidney disease: are we nearly there yet? Curr Opin Nephrol Hypertens. 2020 Jan;29(1):119-127. doi: 10.1097/MNH.0000000000000558. PMID: 31599748.
  • Fu T, Mohan M, Brennan EP, Woodman OL, Godson C, Kantharidis P, Ritchie RH, Qin CX. Therapeutic Potential of Lipoxin A<sub>4</sub> in Chronic Inflammation: Focus on Cardiometabolic Disease. ACS Pharmacol Transl Sci. 2020 Jan 17;3(1):43-55. doi: 10.1021/acsptsci.9b00097. PMID: 32259087; MCID: PMC7088989.
  • Benson KA, Murray SL, Doyle R, Doyle B, Dorman AM, Sadlier D, Brennan E,nLarge M, Cavalleri GL, Godson C, Conlon PJ. Diagnostic utility of genetic testing in patients undergoing renal biopsy. Cold Spring Harb Mol Case Stud. 2020 Oct 7;6(5):a005462. doi: 10.1101/mcs.a005462. PMID: 32723786; MCID: PMC7552929.
  • Wilkinson M, Sinclair P, Dellatorre-Teixeira L, Swan P, Brennan E, Moran B, edekind D, Downey P, Sheahan K, Conroy E, Gallagher WM, Docherty N, Roux CL, Brennan DJ. The Molecular Effects of a High Fat Diet on Endometrial Tumour Biology. Life (Basel). 2020 Sep 10;10(9):188. doi: 3390/life10090188. PMID: 32927694; PMCID: PMC7554710.
  • Nair M, Martin WP, Zhernovkov V, Elliott JA, Fearon N, Eckhardt H, McCormack J, Godson C, Brennan EP, Fandriks L, Docherty NG, le Roux CW. Characterization of the renal cortical transcriptome following Roux-en-Y gastric bypass surgery in experimental diabetic kidney disease. BMJ Open Diabetes Res Care. 2020 Jul;8(1):e001113. doi: 10.1136/bmjdrc-2019-001113. Erratum in: BMJ Open Diabetes Res Care. 2020 Aug;8(1): PMID: 32747384; PMCID: PMC7398104.
  • Fitzsimons S, Oggero S, Bruen R, McCarthy C, Strowitzki MJ, Mahon NG, Ryan N, Brennan EP, Barry M, Perretti M, Belton O. microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression. Front Immunol. 2020 Dec 17;11:576516. doi: 10.3389/fimmu.2020.576516. PMID: 33391256; PMCID: PMC7773661.
  • Maciuszek M, Cacace A, Brennan E, Godson C, Chapman TM. Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential. Eur J Med Chem. 2021 Mar 5;213:113167. doi: 10.1016/j.ejmech.2021.113167. Epub 2021 Jan 12. PMID: 33486199.
  • Oggero S, de Gaetano M, Marcone S, Fitzsimons S, Pinto AL, Ikramova D, Barry M, Burke D, Montero-Melendez T, Cooper D, Burgoyne T, Belton O, Norling LV, Brennan EP, Godson C, Perretti M. Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity. J Extracell Vesicles. 2021 Apr;10(6):12084. doi: 10.1002/jev2.12084. Epub 2021 Apr 27. PMID: 33936566; PMCID: PMC8077084.

 

2019

  • Al-Ozairi E, AlAwadhi MM, Al Kandari J, Taghadom E, Abdullah M, Le Roux CW. Photo-Assisted Dietary Method Improves Estimates of Dietary Intake Among People with Sleeve Gastrectomy. Obes Surg. 2019 Feb 13. doi: 10.1007/s11695-019-03736-4. [Epub ahead of print].
  • Andrews D, Oliviero G, De Chiara L, Watson A, Rochford E, Wynne K, Kennedy C, Clerkin S, Doyle B, Godson C, Connell P, O'Brien C, Cagney G, Crean J. Unravelling the transcriptional responses of TGF-β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification. FASEB J. 2019 Feb 19:fj201800566RR. doi: 10.1096/fj.201800566RR. [Epub ahead of print].
  • Braga T, Kraemer-Aguiar LG, Docherty NG, Le Roux CW. Treating prediabetes: why and how should we do it? Minerva Med. 2019 Feb;110(1):52-61. doi: 10.23736/S0026-4806.18.05897-4. Epub 2018 Oct 29. Review.
  • Crifo B, Schaible B, Brown E, Halligan DN, Scholz CC, Fitzpatrick SF, Kirwan A, Roche HM, Criscuoli M, Naldini A, Giffney H, Crean D, Blanco A, Cavadas MA, Cummins EP, Fabian Z, Taylor CT. Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes. J Immunol. 2019 Mar 1;202(5):1521-1530. doi: 10.4049/jimmunol.1800912. Epub 2019 Jan 30.
  • de Gaetano M, Butler E, Gahan K, Zanetti A, Marai M, Chen J, Cacace A, Hams E, Maingot C, McLoughlin A, Brennan E, Leroy X, Loscher CE, Fallon P, Perretti M, Godson C, Guiry PJ. Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A4 mimetics (sLXms). Eur J Med Chem. 2019 Jan 15;162:80-108. doi: 0.1016/j.ejmech.2018.10.049. Epub 2018 Oct 23.
  • Elliott JA, Casey S, Murphy CF, Docherty NG, Ravi N, Beddy P, Reynolds JV, le Roux CW. Risk factors for loss of bone mineral density after curative esophagectomy. Arch Osteoporos. 2019 Jan 9;14(1):6. doi: 10.1007/s11657-018-0556-z.
  • Elliott JA, Docherty NG, Haag J, Eckhardt HG, Ravi N, Reynolds JV, le Roux CW. Attenuation of satiety gut hormones increases appetitive behavior after curative esophagectomy for esophageal cancer. Am J Clin Nutr. 2019 Feb 1;109(2):335-344. doi: 10.1093/ajcn/nqy324.
  • Lenighan YM, McNulty BA, Roche HM. Dietary fat composition: replacement of saturated fatty acids with PUFA as a public health strategy, with an emphasis on α-linolenic acid. Proc Nutr Soc. 2019 Jan 11:1-12. doi: 10.1017/S0029665118002793. [Epub ahead of print].
  • O'Reilly ME, Kajani S, Ralston JC, Lenighan YM, Roche HM, McGillicuddy FC. utritionally Derived Metabolic Cues Typical of the Obese Microenvironment Increase Cholesterol Efflux Capacity of Adipose Tissue Macrophages. Mol Nutr Food Res. 2019 Jan;63(2):e1800713. doi: 10.1002/mnfr.201800713. Epub 2018 Nov 20.
  • Roche HM. Dietary modulation of energy homoeostasis and metabolic-inflammation. Proc Nutr Soc. 2019 Feb 1:1-6. doi: 10.1017/S0029665118002872. [Epub ahead of print]
  • Suliman M, Buckley A, Al Tikriti A, Tan T, le Roux CW, Lessan N, Barakat M. Routine clinical use of Liraglutide 3 mg for the treatment of obesity: Outcomes in non-surgical and bariatric surgery patients. Diabetes Obes Metab. 2019 Feb 15. doi: 10.1111/dom.13672. [Epub ahead of print]

 

2018

  • Al-Najim W, Docherty NG, le Roux CW. Food Intake and Eating Behavior After Bariatric Surgery. Physiol Rev. 2018 Jul 1;98(3):1113-1141. doi: 10.1152/physrev.00021.2017. Review.
  • Al-Najim W, le Roux CW. Pharmacotherapy in conjunction with lifestyle for the treatment of obesity complications, is it enough?Ann Transl Med. 2018 Dec;6(Suppl 2):S109. doi: 10.21037/atm.2018.11.60. No abstract available.
  • Al-Najim W, le Roux CW, Docherty NG. Integrated insights into the role of alpha-melanocyte stimulatory hormone in the control of food intake and glycaemia. Peptides. 2018 Feb;100:243-248. doi: 10.1016/j.peptides.2017.12.003. Review.·        
  • Abdeen GN, Miras AD, Alqhatani AR, le Roux CW. Sugar Detection Threshold After Laparoscopic Sleeve Gastrectomy in Adolescents. Obes Surg. 2018 May;28(5):1302-1307. doi: 10.1007/s11695-017-2999-5.
  • Balfe A, Lennon G, Lavelle A, Docherty NG, Coffey JC, Sheahan K, Winter DC, O'Connell PR. Isolation and gene expression profiling of intestinal epithelial cells: crypt isolation by calcium chelation from in vivo samples. Clin Exp Gastroenterol. 2018 Jan 12;11:29-37. doi: 10.2147/CEG.S145224. eCollection 2018.
  • Bass GA, Heneghan HM. Negative Press for Intraoperative Provocative Testing in Bariatric Surgery-Blown Out of Proportion? J Am Coll Surg. 2018 Oct;227(4):475. doi: 10.1016/j.jamcollsurg.2018.07.002. No abstract available.
  • Brennan EP, Mohan M, McClelland A, Tikellis C, Ziemann M, Kaspi A, Gray SP, Pickering R, Tan SM, Ali-Shah ST, Guiry PJ, El-Osta A, Jandeleit-Dahm K, Cooper ME, Godson C, Kantharidis P. Lipoxins Regulate the Early Growth Response-1 Network and Reverse Diabetic Kidney Disease. J Am Soc Nephrol. 2018 May;29(5):1437-1448. doi: 10.1681/ASN.2017101112. Epub 2018 Feb 28.
  • Brennan EP, Mohan M, McClelland A, de Gaetano M, Tikellis C, Marai M, Crean D, Dai A, Beuscart O, Derouiche S, Gray SP, Pickering R, Tan SM, Godson-Treacy M, Sheehan S, Dowdall JF, Barry M, Belton O, Ali-Shah ST, Guiry PJ, Jandeleit-Dahm K, Cooper ME, Godson C, Kantharidis P. Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis. Diabetes. 2018 Dec;67(12):2657-2667. doi: 10.2337/db17-1317. Epub 2018 Sep 13.
  • Christensen BJ, Schmidt JB, Nielsen MS, Tækker L, Holm L, Lunn S, Bredie WLP, Ritz C, Holst JJ, Hansen T, Hilbert A, le Roux CW, Hulme OJ, Siebner H, Morville T, Naver L, Floyd AK, Sjödin A. Patient profiling for success after weight loss surgery (GO Bypass study): An interdisciplinary study protocol. Contemp Clin Trials Commun. 2018 Feb 17;10:121-130. doi: 10.1016/j.conctc.2018.02.002. eCollection 2018 Jun.
  • Chuah LL, Miras AD, Perry LM, Frankel AH, Towey DJ, Al-Mayahi Z, Svensson W, le Roux CW. Measurement of glomerular filtration rate in patients undergoing obesity surgery. BMC Nephrol. 2018 Dec 29;19(1):383. doi: 10.1186/s12882-018-1188-7.
  • Craig H, le Roux C, Keogh F, Finucane FM. How Ethical Is Our Current Delivery of Care to Patients with Severe and Complicated Obesity? Obes Surg. 2018 Jul;28(7):2078-2082. doi: 10.1007/s11695-018-3301-1. Review.
  • Curran AM, Scott-Boyer MP, Kaput J, Ryan MF, Drummond E, Gibney ER, Gibney MJ, Roche HM, Brennan L. A proteomic signature that reflects pancreatic beta-cell function. PLoS One. 2018 Aug 30;13(8):e0202727. doi: 10.1371/journal.pone.0202727. eCollection 2018.
  • de Gaetano M, McEvoy C, Andrews D, Cacace A, Hunter J, Brennan E, Godson C. Specialized Pro-resolving Lipid Mediators: Modulation of Diabetes-Associated Cardio-, Reno-, and Retino-Vascular Complications. Front Pharmacol. 2018 Dec 19;9:1488. doi: 10.3389/fphar.2018.01488. eCollection 2018. Review.
  • Doody A, Jackson S, Elliott JA, Canavan RJ, Godson C, Slattery D, Twomey PJ, McKenna MJ, le Roux CW, Docherty NG. Validating the association between plasma tumour necrosis factor receptor 1 levels and the presence of renal injury and functional decline in patients with Type 2 diabetes. J Diabetes Complications. 2018 Jan;32(1):95-99. doi: 10.1016/j.jdiacomp.2017.09.007. Epub 2017 Sep 18.
  • Doyle R, Sadlier DM, Godson C. Semin. Pro-resolving lipid mediators: Agents of anti-ageing? Immunol. 2018 Dec; 40:36-48. doi: 10.1016/j.smim.2018.09.002. Epub 2018 Oct 4. Review. PMID: 30293857.
  • Elliott JA, Casey S, Murphy CF, Docherty NG, Ravi N, Beddy P, Reynolds JV, le Roux CW. Risk factors for loss of bone mineral density after curative esophagectomy. Arch Osteoporos. 2019 Jan 9;14(1):6. doi: 10.1007/s11657-018-0556-z.
  • Fatima A, Connaughton RM, Weiser A, Murphy AM, O'Grada C, Ryan M, Brennan L, O'Gaora P, Roche HM. Weighted Gene Co-Expression Network Analysis Identifies Gender Specific Modules and Hub Genes Related to Metabolism and Inflammation in Response to an Acute Lipid Challenge. Mol Nutr Food Res. 2018 Jan;62(2). doi: 10.1002/mnfr.201700388. Epub 2017 Dec 11.
  • Friedman AN, Wahed AS, Wang J, Courcoulas AP, Dakin G, Hinojosa MW, Kimmel PL, Mitchell JE, Pomp A, Pories WJ, Purnell JQ, le Roux C, Spaniolas K, Steffen KJ, Thirlby R, Wolfe B. Effect of Bariatric Surgery on CKD Risk. J Am Soc Nephrol. 2018 Apr;29(4):1289-1300. doi: 10.1681/ASN.2017060707. Epub 2018 Jan 15.
  • Glaysher MA, Mohanaruban A, Prechtl CG, Goldstone AP, Miras AD, Lord J, Chhina N, Falaschetti E, Johnson NA, Al-Najim W, Smith C, Li JV, Patel M, Ahmed AR, Moore M, Poulter N, Bloom S, Darzi A, Le Roux C, Byrne JP, Teare JP. A randomised controlled trial of a duodenal-jejunal bypass sleeve device (EndoBarrier) compared with standard medical therapy for the management of obese subjects with type 2 diabetes mellitus. BMJ Open. 2017 Nov 15;7(11):e018598. doi: 10.1136/bmjopen-2017-018598.
  • Heneghan HM, Kerrigan DD. Laparoscopic SADI-S as a salvage procedure for failed gastric bypass and sleeve gastrectomy: How I do it. Surg Obes Relat Dis. 2018 May;14(5):715-718. doi: 10.1016/j.soard.2018.01.043. Epub 2018 Feb 7. No abstract available.
  • Hughes MF, Lenighan YM, Godson C, Roche HM. Exploring Coronary Artery Disease GWAs Targets With Functional Links to Immunometabolism. Front Cardiovasc Med. 2018 Nov 6;5:148. doi: 10.3389/fcvm.2018.00148. eCollection 2018. Review.
  • Jain AK, le Roux CW, Puri P, Tavakkoli A, Gletsu-Miller N, Laferrère B, Kellermayer R, DiBaise JK, Martindale RG, Wolfe BM. Proceedings of the 2017 ASPEN Research Workshop-Gastric Bypass: Role of the Gut.
  • Kajani S, Curley S, McGillicuddy FC. Unravelling HDL-Looking beyond the Cholesterol Surface to the Quality Within. Int J Mol Sci. 2018 Jul 6;19(7). pii: E1971. doi: 10.3390/ijms19071971. Review. JPEN J Parenter Enteral Nutr. 2018 Feb;42(2):279-295. doi: 10.1002/jpen.1121. Review.
  • le Roux C, Aroda V, Hemmingsson J, Cancino AP, Christensen R, Pi-Sunyer X. Comparison of Efficacy and Safety of Liraglutide 3.0 mg in Individuals with BMI above and below 35 kg/m²: A Post-hoc Analysis.Obes Facts. 2017;10(6):531-544. doi: 10.1159/000478099. Epub 2017 Nov 17.
  • le Roux CW, Schauer PR. Prevention Is Better Than Cure: The Next Frontier for Bariatric Surgery? Ann Intern Med. 2018 Sep 4;169(5):343-344. doi: 10.7326/M18-2114. Epub 2018 Aug 7. No abstract available.
  • le Roux CW, Heneghan HM. Bariatric Surgery for Obesity. Med Clin North Am. 2018 Jan;102(1):165-182. doi: 10.1016/j.mcna.2017.08.011. Review.
  • Lyons CL, Roche HM. Nutritional Modulation of AMPK-Impact upon Metabolic-Inflammation. Int J Mol Sci. 2018 Oct 9;19(10). pii: E3092. doi: 10.3390/ijms19103092. Review.
  • Mangan A, Docherty NG, Le Roux CW, Al-Najim W. Current and emerging pharmacotherapy for prediabetes: are we moving forward? Expert Opin Pharmacother. 2018 Oct;19(15):1663-1673. doi: 10.1080/14656566.2018.1517155. Epub 2018 Sep 10. Review.
  • Mangan A, Le Roux CW, Miller NG, Docherty NG. Iron and Vitamin D/Calcium Deficiency after Gastric Bypass: Mechanisms Involved and Strategies to Improve Oral Supplement Disposition. Curr Drug Metab. 2018 Oct 26. doi: 10.2174/1389200219666181026160242. [Epub ahead of print].
  • Martin WP, Docherty NG, Le Roux CW. Impact of bariatric surgery on cardiovascular and renal complications of diabetes: a focus on clinical outcomes and putative mechanisms.Expert Rev Endocrinol Metab. 2018 Sep;13(5):251-262. doi: 10.1080/17446651.2018.1518130. Epub 2018 Sep 19.
  • McMorrow AM, Connaughton RM, Magalhães TR, McGillicuddy FC, Hughes MF, Cheishvili D, Morine MJ, Ennis S, Healy ML, Roche EF, Tremblay RE, Szyf M, Lithander FE, Roche HM. Personalized Cardio-Metabolic Responses to an Anti-Inflammatory Nutrition Intervention in Obese Adolescents: A Randomized Controlled Crossover Trial. Mol Nutr Food Res. 2018 May;62(10):e1701008. doi: 10.1002/mnfr.201701008.
  • Mingrone G, Bornstein S, Le Roux CW. Optimisation of follow-up after metabolic surgery. Lancet Diabetes Endocrinol. 2018 Jun;6(6):487-499. doi: 10.1016/S2213-8587(17)30434-5. Epub 2018 Jan 29. Review.
  • Miras AD, Kamocka A, Patel D, Dexter S, Finlay I, Hopkins JC, Khan O, Reddy M, Sedman P, Small P, Somers S, Cro S, Walton P, le Roux CW, Welbourn R. Obesity surgery makes patients healthier and more functional: real world results from the United Kingdom National Bariatric Surgery Registry. Surg Obes Relat Dis. 2018 Jul;14(7):1033-1040. doi: 10.1016/j.soard.2018.02.012. Epub 2018 Feb 15.
  • Miras AD, le Roux CW. Surgery: The new gold-standard - medical gastric bypass. Nat Rev Endocrinol. 2018 May;14(5):257-258. doi: 10.1038/nrendo.2018.28. Epub 2018 Mar 16. No abstract available.
  • Murphy CF, Docherty NG, le Roux CW. Liraglutide: another reason to target prediabetes?
  • Murphy CF, le Roux CW. Can we exonerate GLP-1 receptor agonists from blame for adverse pancreatic events? Ann Transl Med. 2018 May;6(10):186. doi: 10.21037/atm.2018.03.06. No abstract available.
  • Ooi GJ, Earnest A, Doyle L, Laurie C, Wentworth JM, Sikaris K, le Roux CW, Burton PR, O'Brien PE, Brown WA. Detailed Description of Change in Serum Cholesterol Profile with Incremental Weight Loss After Restrictive Bariatric Surgery. Obes Surg. 2018 May;28(5):1351-1362. doi: 10.1007/s11695-017-3015-9.
  • Patel N, Mohanaruban A, Ashrafian H, Le Roux C, Byrne J, Mason J, Hopkins J, Kelly J, Teare J. EndoBarrier®: a Safe and Effective Novel Treatment for Obesity and Type 2 Diabetes? Obes Surg. 2018 Jul;28(7):1980-1989. doi: 10.1007/s11695-018-3123-1.
  • Roncero-Ramos I, Rangel-Zuñiga OA, Lopez-Moreno J, Alcala-Diaz JF, Perez-Martinez P, Jimenez-Lucena R, Castaño JP, Roche HM, Delgado-Lista J, Ordovas JM, Camargo A, Lopez-Miranda J. Mediterranean Diet, Glucose Homeostasis, and Inflammasome Genetic Variants: The CORDIOPREV Study. Mol Nutr Food Res. 2018 May;62(9):e1700960. doi: 10.1002/mnfr.201700960. Epub 2018 Apr 20.
  • Sergi D, Campbell FM, Grant C, Morris AC, Bachmair EM, Koch C, McLean FH, Muller A, Hoggard N, de Roos B, Porteiro B, Boekschoten MV, McGillicuddy FC, Kahn D, Nicol P, Benzler J, Mayer CD, Drew JE, Roche HM, Muller M, Nogueiras R, Dieguez C, Tups A, Williams LM. SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice. Genes Nutr. 2018 Nov 29;13:28. doi: 10.1186/s12263-018-0619-1. eCollection 2018.
  • Shulman A, Peltonen M, Andersson-Assarsson JC, Sjöholm K, le Roux CW, Svensson PA. Reply: Bariatric surgery and chronic kidney disease: much hope, but proof is still awaited. Int J Obes (Lond). 2018 Aug;42(8):1534. doi: 10.1038/s41366-018-0159-1. Epub 2018 Jul 17. No abstract available.
  • Sinclair P, Brennan DJ, le Roux CW. Gut adaptation after metabolic surgery and its influences on the brain, liver and cancer. Nat Rev Gastroenterol Hepatol. 2018 Oct;15(10):606-624. doi: 10.1038/s41575-018-0057-y. Review.
  • Sinclair P, Docherty N, le Roux CW. Metabolic Effects of Bariatric Surgery. Clin Chem. 2018 Jan;64(1):72-81. doi: 10.1373/clinchem.2017.272336. Epub 2017 Nov 21. Review.
  • Sladek S, Kearney C, Crean D, Brama PAJ, Tajber L, Fawcett K, Labberte MC, Leggett B, Brayden DJ. Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation. Drug Deliv Transl Res. 2018 Oct;8(5):1421-1435. doi: 10.1007/s13346-018-0557-x.
  • Søndergaard Nielsen M, Rasmussen S, Just Christensen B, Ritz C, le Roux CW, Berg Schmidt J, Sjödin A. Bariatric Surgery Does Not Affect Food Preferences, but Individual Changes in Food Preferences May Predict Weight Loss. Obesity (Silver Spring). 2018 Dec;26(12):1879-1887. doi: 10.1002/oby.22272. Epub 2018 Nov 13.
  • Spector AC, Kapoor N, Price RK, Pepino MY, E Livingstone MB, le Roux CW. Proceedings from the 2018 Association for Chemoreception Annual Meeting Symposium: Bariatric Surgery and Its Effects on Taste and Food Selection. Chem Senses. 2018 Dec 4. doi: 10.1093/chemse/bjy076. [Epub ahead of print].
  • Tang T, Abbott S, le Roux CW, Wilson V, Singhal R, Bellary S, Tahrani AA. Preoperative weight loss with glucagon-like peptide-1 receptor agonist treatment predicts greater weight loss achieved by the combination of medical weight management and bariatric surgery in patients with type 2 diabetes: A longitudinal analysis. Diabetes Obes Metab. 2018 Mar;20(3):745-748. doi: 10.1111/dom.13131. Epub 2017 Nov 22.
  • Wallenius V, Dirinck E, Fändriks L, Maleckas A, le Roux CW, Thorell A. Glycemic Control after Sleeve Gastrectomy and Roux-En-Y Gastric Bypass in Obese Subjects with Type 2 Diabetes Mellitus. Obes Surg. 2018 Jun;28(6):1461-1472. doi: 10.1007/s11695-017-3061-3.
  • van Zuydam NR, Ahlqvist E, Sandholm N, Deshmukh H, …. Brennan EP, Sadlier DM, Martin F, Godson C,….McCarthy MI. A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. Diabetes. 2018 Jul;67(7):1414-1427. doi: 10.2337/db17-0914. Epub 2018 Apr 27.·         Werling M, Fändriks L, Olbers T, Mala T, Kristinsson J, Stenlöf K, Wallenius V, Docherty NG, le Roux CW. Biliopancreatic Diversion is associated with greater increases in energy expenditure than Roux-en-Y Gastric Bypass. PLoS One. 2018 Apr 4;13(4):e0194538. doi: 10.1371/journal.pone.0194538. eCollection 2018.

 

2017

  • Arora T, Seyfried F, Docherty N.G, le Roux C.W, Perkins R, Bäckhed F Diabetes-associated microbiota in fa/fa rats is modified by Roux-en-Y gastric bypass International Society of Microbial Ecology Journal (ISME) 2017. 11(9):2035-2046 201.
  • Borgeson E, Wallenius, Syed, GH Darshi, M Rodriguez JL Bioresrud C Ragnmark Ek M Bjorklund P, Quiding-Jabrink, M Fandriks L Godson C* Sharma, K High-fat diet-induced pathophysiology is reduced by AICAR in an adiponectin-independent manner Diabetalogia 2017 Apr;60(4):729-739.
  • Boulenouar S, Michelet X, Duquette D, Alvarez D, Hogan AE, Dold C, O'Connor D, Stutte S, Tavakkoli A, Winters D, Exley MA, O'Shea D, Brenner MB, von Andrian U, Lynch L. Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity Immunity. 2017 Feb 21;46(2):273-286. PMID: 28228283.
  • Brennan E, Wang B, McClelland A, Mohan M, Marai M, Beuscart O, Derouiche S, Gray S, Pickering R, Tikellis C, de Gaetano M, Barry M, Belton O, Ali-Shah ST, Guiry P, Jandeleit-Dahm KAM, Cooper ME, Godson C, Kantharidis P. Protective Effect of let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis. Diabetes. 2017 Aug;66(8):2266-2277.
  • Brennan EP, Cacace A, Godson C. Specialized pro-resolving mediators in renal fibrosis. Mol Aspects Med. 2017 May 11.
  • Bruen R, Curley S, Kajani S, Crean D, O'Reilly ME, Lucitt MB, Godson CG, McGillicuddy FC, Belton O. Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis. Cardiovasc Diabetol. 2017 Nov 6;16(1):143-156.
  • Bruen R, Fitzsimons S, Belton O. Atheroprotective effects of conjugated linoleic acid. Br J Clin Pharmacol. 2017 Jan;83(1):46-53.
  • Cohen R, Le Roux CW, Junqueira S, Ribeiro RA, Luque A. Roux-En-Y Gastric Bypass in Type 2 Diabetes Patients with Mild Obesity: a Systematic Review and Meta-analysis. Obes Surg. 2017 Aug 7.
  • Cohen RV, Luque A, Junqueira S, Ribeiro RA, Le Roux CW. What is the impact on the healthcare system if access to bariatric surgery is delayed? Surg Obes Relat Dis. 2017 Sep;13(9):1619-1627. doi: 10.1016/j.soard.2017.03.025. Epub 2017 Mar 31. PMID: 28499887.
  • Cummins EP, Crean D. 'Hypoxia and Inflammatory Bowel Disease.' Microbes and infection. 2017; 19(3):210-21.
  • DeChiara L., Andrews D., Watson A., Oliviero G.,  Cagney G. and Crean J. miR302 regulates SNAI1 expression to control mesangial cell plasticity Scientific Reports, 2017, in press.
  • Docherty N.G, Fändriks L, le Roux C.W, Hallesrund P, Werling M. Urinary Sodium Excretion after Gastric Bypass Surgery Surgery for Obesity and Related Diseases (SOARD)  13(9):1506-1514 2017.
  • Doody A, Jackson, S, Elliott JA, Canavan R, Godson C, Slattery D, Twomey P, McKenna M, le Roux CW, Docherty NG 1Validating the Association between Plasma Tumour Necrosis Factor Receptor 1 Levels and the Presence of Renal Injury and Functional Decline in Patients with Type 2 Diabetes Journal of Diabetes & its Complications 2017 [Epub ahead of print].
  • Elliott JA, Docherty N.G, Eckhardt HG, Doyle SL, Guinan EM, Ravi N, Reynolds JV, Roux CW. Weight Loss, Satiety, and the Postprandial Gut Hormone Response After Esophagectomy: A Prospective Study. Annals of  Surgery  266(1):82-90 2017.
  • Higgins DF, Ewart LM, Masterson E, Tennant S, Grebnev G, Prunotto M, Pomposiello S, Conde-Knape K, Martin FM, Godson C. BMP7-induced-Pten inhibits Akt and prevents renal fibrosis. Biochim Biophys Acta. 2017 Sep 18;1863(12):3095-3104.
  • Hyde KM, Blonde GD, le Roux CW, Spector AC. Liraglutide suppression of caloric intake competes with the intake-promoting effects of a palatable cafeteria diet, but does not impact food or macronutrient selection. Physiol Behav. 2017 Aug 1;177:4-12.
  • Laurenius A, Werling M, le Roux CW, Fändriks L, Olbers T. Dumping symptoms is triggered by fat as well as carbohydrates in patients operated with Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2017 Jul;13(7):1159-1164.
  • le Roux CW, Astrup A, Fujioka K, Greenway F, Lau DC, Van Gaal L, Ortiz RV, Wilding JP, Skjøth TV, Manning LS, Pi-Sunyer X; 3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial. SCALE Obesity.; Prediabetes NN8022-1839 Study Group. Lancet. 2017 Feb 22. pii: S0140-6736(17)30069-7.
  • MacLellan GA, Dunlevy C, O'Malley E, Blake C, Breen C, Gaynor K, Wallace N, Yoder R, Casey D, Mehegan J, O'Shea D, Fullen BM. Musculoskeletal pain profile of obese individuals attending a multidisciplinary weight management service Pain. 2017 Apr 5.
  • Marcone S, Belton O, Fitzgerald DJ. Milk-derived bioactive peptides and their health promoting effects: a potential role in atherosclerosis. Br J Clin Pharmacol. 2017 Jan;83(1):152-162.
  • Mazzei L, Cuello-Carrión FD, Docherty NG, Manucha W. Heat shock protein 70/nitric oxide effect on stretched tubular epithelial cells linked to WT-1 cytoprotection during neonatal obstructive nephropathy. Int Urol Nephrol. 2017 [Epub ahead of print].
  • McEvoy C, de Gaetano M, Giffney HE, Bahar B, Cummins EP, Brennan EP, Barry M, Belton O, Godson CG, Murphy EP, Crean D. NR4A Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells. Front Immunol. 2017 Jan 23;8:7.
  • Miras AD, Herring R, Vusirikala A, Shojaee-Moradi F, Jackson NC, Chandaria S, Jackson SN, Goldstone AP, Hakim N, Patel AG, Umpleby AM, Le Roux CW. Measurement of hepatic insulin sensitivity early after the bypass of the proximal small bowel in humans. Obes Sci Pract. 2017 Mar;3(1):95-98.
  • Miras AD, le Roux CW. Metabolic Surgery in a Pill. Cell Metab. 2017 May 2;25(5):985-987.
  • Neff K.J,  Elliott J.A, Jackson S.N,   Corteville C,  Abegg K, Godson C, , Boza C,  Lutz T.A,  Docherty N.G,  le Roux C.W.  Effect of Roux-en-Y Gastric Bypass and Diet induced Weight Loss on Diabetic Kidney Disease in the Zucker Diabetic Fatty Rat Surgery for Obesity and Related Diseases (SOARD) 13(1):21-27 2017.
  • Nielsen MS, Christensen BJ, Ritz C, Rasmussen S, Hansen TT, Bredie WLP, le Roux CW, Sjödin A, Schmidt JB. Roux-En-Y Gastric Bypass and Sleeve Gastrectomy Does Not Affect Food Preferences When Assessed by an Ad libitum Buffet Meal. Obes Surg. 2017 Apr 14.
  • O'Neill KN, Finucane FM, le Roux CW, Fitzgerald AP, Kearney PM. Unmet need for bariatric surgery. Surg Obes Relat Dis. 2017 Jun;13(6):1052-1056. doi: 10.1016/j.soard.2016.12.015. Epub 2016 Dec 23. PMID: 28256395.
  • Ooi GJ, Doyle L, Tie T, Wentworth JM, Laurie C, Earnest A, Cowley MA, Sikaris K, le Roux CW, Burton PR, O'Brien PE, Brown WA. Weight loss after laparoscopic adjustable gastric band and resolution of the metabolic syndrome and its components. Int J Obes (Lond). 2017 Jun;41(6):902-908.
  • Risstad H, Kristinsson JA, Fagerland MW, le Roux CW, Birkeland KI, Gulseth HL, Thorsby PM, Vincent RP, Engström M, Olbers T, Mala T. Bile acid profiles over 5 years after gastric bypass and duodenal switch: results from a randomized clinical trial. Surg Obes Relat Dis. 2017 Sep;13(9):1544-1553.
  • Taha O, Hussein A, Abdelaal M, al-Najim W, le Roux CW, Docherty NG Impact of abdominal subcutaneous fat reduction on glycemic control in obese patients with type 2 diabetes mellitus Bariatric Surgical Practice and Patient Care 2017 in press.
  • Tang T, Abbott S, le Roux CW, Wilson V, Singhal R, Bellary S, Tahrani A. Preoperative Weight Loss With GLP-1 Receptor Agonist Treatment Predicts Greater Weight Loss Achieved by the Combination of Medical Weight Management And Bariatric Surgery In Patients With Type 2 Diabetes: A Longitudinal Analysis. Diabetes Obes Metab. 2017 Oct 20. doi: 10.1111/dom.13131. Epub ahead of print] PMID: 29053203.

 

2016

  • Beaton H, Andrews D, Parsons M, Murphy M, Gaffney A, Kavanagh D, McKay GJ, Maxwell AP, Taylor CT, Cummins EP, Godson C, Higgins DF, Murphy P, Crean J. Wnt6 regulates epithelial cell differentiation and is dysregulated in renal fibrosis Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F35-45.
  • Cavadas MAS, Mesnieres M, Crifo B, Cabrero Manresa M, Selfridge,AC  Fabian Z, Scholz CC, Nolan KA, Rocha LA, Tambuwala MM, Brown S, Wdowicz A, Corbett D, Murphy KJ, Godson C, Cummins EP, TaylorCT, Cheong A REST is a hypoxia-inducible repressor of transcription  Sci Reports 2016.
  • Coluzzi I, Raparelli L, Guarnacci L, Paone E, Del Genio G, le Roux CW, Silecchia G. Food Intake and Changes in Eating Behavior After Laparoscopic Sleeve Gastrectomy. Obes Surg. 2016 Jan 7. [Epub ahead of print] PMID: 26744284.
  • Connaughton RM, McMorrow AM, McGillicuddy FC, Lithander FE, Roche HM. Impact of anti-inflammatory nutrients on obesity-associated metabolic-inflammation from childhood through to adulthood. Proc Nutr Soc 75(02):115-124, 2016.
  • Cummins EP, Keogh CE, Crean D, Taylor CT. 'The Role of HIF in Immunity and Inflammation.' Mol Aspects Med. 2016; 47-48:24-34.
  • De Chiara L, Crean J. Emerging Transcriptional Mechanisms in the Regulation of Epithelial to Mesenchymal Transition and Cellular Plasticity in the Kidney. J Clin Med. 2016 Jan 12; 5(1). pii: E6. doi: 10.3390/jcm5010006.
  • de Gaetano M, Crean D, Barry M, Belton O. M1- and M2-Type Macrophage Responses Are Predictive of Adverse Outcomes in Human Atherosclerosis. Front Immunol. 2016 Jul 19;7:275. doi: 10.3389/fimmu.2016.00275.
  • Dutia R, Embrey M, O'Brien S, Haeusler RA, Agénor KK, Homel P, McGinty J, Vincent RP, Alaghband-Zadeh J, Staels B, le Roux CW, Yu J, Laferrère B. Temporal changes in bile acid levels and 12α-hydroxylation after Roux-en-Y gastric bypass surgery in type 2 diabetes. Int J Obes (Lond). 2016 Mar;40(3):554.
  • Elliott JA, le Roux CW. Type 2 diabetes with BMI<30 kg/m2: Can we predict success of metabolic surgery? Surg Obes Relat Dis. 2016 Mar 16. pii: S1550-7289(16)00102-7. doi: 10.1016/j.soard.2016.03.012. PMID: 27130137.
  • Gaul D, Mat A, O'Shea D, Issartel J. Impaired Visual Motor Coordination in Obese Adults., J Obes. 2016;2016:6178575. Epub 2016 Nov 22. PMID: 27994885.
  • Healy NP, Kirwan AM, McArdle MA, Holohan K, Nongonierma AB, Keane D, Kelly S, Celkova L, Lyons CL, McGillicuddy FC, Finucane OM, Murray BA, Kelly PM, Brennan L, Fitzgerald RJ, Roche HM. A casein hydrolysate protects mice against high fat diet induced hyperglycemia by attenuating NLRP3 inflammasome‐mediated inflammation and improving insulin signaling.  Mol Nutr Food Res 2016.
  • Hunt KF, Dunn JT, le Roux CW, Reed LJ, Marsden PK, Patel AG, Amiel SA. Differences in Regional Brain Responses to Food Ingestion After Roux-en-Y Gastric Bypass and the Role of Gut Peptides: A Neuroimaging Study. Diabetes Care. 2016 Oct;39(10):1787-95. doi: 10.2337/dc15-2721. PMID: 27660120.
  • Jung J, Ha TK, Lee J, Lho Y, Nam M, Lee D, le Roux CW, Ryu DH, Ha E, Hwang GS. Changes in one-carbon metabolism after duodenal-jejunal bypass surgery. Am J Physiol Endocrinol Metab. 2016 Jan 19:ajpendo.00260.2015.
  • le Roux C.W, Engstrom M,, Bjornfot N,, Fandriks L, Docherty N.G Equivalent Increases in Circulating GLP-1 Following Jejunal Delivery of Intact and Hydrolysed Casein: Relevance to Satiety Induction Following Bariatric Surgery. Obesity surgery 26(8):1851-8 2016.
  • Lynch L, Hogan AE, Duquette D, Lester C, Banks A, LeClair K, Cohen DE, Ghosh A, Lu B, Corrigan M, Stevanovic D, Maratos-Flier E, Drucker DJ, O'Shea D, Brenner M. iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy. Cell Metab. 2016 Sep 13;24(3):510-9.PMID: 27593966.
  • Lyons CL, Kennedy EB, Roche HM, 2016. Metabolic Inflammation-Differential Modulation by Dietary Constituents. Nutrients, 8(5):247, 2016.
  • Maghsoodi N, Alaghband-Zadeh J, Cross G, Werling M, Fandriks L, Docherty NG, Olbers T, Dew T, Sherwood R, Vincent R.P, Le Roux C.W. Elevated Fasting & Post-prandial C-Terminal Telopeptide (CTX) after Roux-en-Y gastric bypass (RYGB). Ann Clin Biochem. 54(4):495-500 2016.
  • Mathes CM, Letourneau C, Blonde GD, le Roux CW, Spector AC. Roux-en-Y Gastric Bypass in Rats Progressively Decreases the Proportion of Fat Calories Selected from a Palatable Cafeteria Diet. Am J Physiol Regul Integr Comp Physiol. 2016 Feb 10:ajpregu.00444.2015.
  • McDarby F, O'Hora D, O'Shea D, Byrne M. Pediatr Obes. Taking the sweetness out of the 'Share a Coke' marketing campaign: the influence of personalized labelling on elementary school children's bottled drink choices 2016 Nov 24. doi: 10.1111/ijpo.12193. PMID: 27884050.
  • McKay, G., Kavanagh, D., Crean, J., Maxwell, A.P. Bioinformatic evaluation of transcriptional regulation of WNT pathway genes with reference to diabetic nephropathy. Journal of Diabetes Research, 2016:7684038. doi: 10.1155/2016/7684038.
  • McKenna I, Hughes S, Barnes-Holmes D, De Schryver M, Yoder R, O'Shea D. Obesity, food restriction, and implicit attitudes to healthy and unhealthy foods: Lessons learned from the implicit relational assessment procedure. Appetite. 2016 May 1;100:41-54. doi: 10.1016/j.appet.2016.02.013. Epub 2016 Feb 11. PMID: 2687721
  • Mossberg KE, Pournaras DJ, Welbourn R, le Roux CW, Brogren H. Differential response of plasma plasminogen activator inhibitor 1 after weight loss surgery in patients with or without type 2 diabetes. Surg Obes Relat Dis. 2016 Mar 14. PMID: 27387691.
  • Neff KJ, Baud G, Raverdy V, Caiazzo R, Verkindt H, Noel C, le Roux CW, Pattou F. Renal Function and Remission of Hypertension After Bariatric Surgery: a 5-Year Prospective Cohort Study. Obes Surg. 2016 Sep 14. PMID: 27628054.
  • Neff KJ, le Roux CW. Bariatric surgery: traversing the CROSSROADS into mainstream diabetes care. Diabetologia. 2016 May;59(5):942-4. doi: 10.1007/s00125-016-3928-1. Epub 2016 Mar 16. No abstract available. PMID: 26983923.
  • O’Reilly M, Dillon E, Guo W, Finucane O, McMorrow A, Murphy A, Lyons C, Jones D, Ryan M, Gibney M, Gibney E, Brennan L, de la Llera Moya M, Reilly M.P, Roche H M, McGillicuddy FC. High-Density Lipoprotein Proteomic Composition, and not Efflux Capacity, Reflects Differential Modulation of Reverse Cholesterol Transport by Saturated and Monounsaturated Fat Diets.  Circulation 133, 1838-1850, 2016. DOI: 10.1161/CIRCULATIONAHA.115.020278. 
  • O’Sullivan S, Jun Wang J , Docherty N.G, , Noreen Boyle2 Kana-Lis S, Gilmer J, Medina C. Inhibition of Matrix Metalloproteinase-9 by a Barbituate-Nitrate Hybrid Ameliorates Dextran Sulphate Sodium-Induced Colitis-Effect on Inflammation Related Genes British Journal of Pharmacology 174(7):512-524 2016.
  • Oliverio G., O’Brien GL, Watson A, Streubel G, Jerman E, Andrews D, Doyle B, Munawar N, Bracken A, Crean J, Cagney G. Dynamic Protein interactions of the Polycomb Repressive Complex 2 during differentiation of pluripotent cells. Molecular and Cellular Proteomics, 2016. doi: 10.1074/mcp.M116.062240.
  • Pournaras DJ, Hardwick RH, le Roux CW. Gastrointestinal surgery for obesity and cancer: 2 sides of the same coin. Surg Obes Relat Dis. 2016 Dec 23. pii: S1550-7289(16)30878-4. doi: 10.1016/j.soard.2016.12.014. [Epub ahead of print] PMID: 28161354.
  • Pournaras DJ, Nygren J, Hagström-Toft E, Arner P, le Roux CW, Thorell A. Improved glucose metabolism after gastric bypass: evolution of the paradigm. Surg Obes Relat Dis. 2016 Mar 23. PMID: 27387696
  • Qvigstad E, Gulseth HL, Risstad H, le Roux CW, Berg TJ, Mala T, Kristinsson JA. A novel technique of Roux-en-Y gastric bypass reversal for postprandial hyperinsulinemic hypoglycaemia: A case report. Int J Surg Case Rep. 2016 Feb 27;21:91-94. doi: 10.1016/j.ijscr.2016.02.033. PMID: 26957187.
  • van Avesaat M, Troost FJ, Westerterp-Plantenga MS, Helyes Z, le Roux CW, Dekker J, Masclee AA, Keszthelyi D. Capsaicin-induced satiety is associated with gastrointestinal distress but not with the release of satiety hormones. Am J Clin Nutr. 2016 Feb;103(2):305-13.
  • Wang B, Yao K, Huuskes BM, Shen H-H, Zhuang J, Godson C, Brennan EP, Wilkinson-Berka JL, Wise AF, Ricardo SD. Mesenchymal stem cells deliver exogenous microRNA let7c via exosomes to attenuate renal fibrosis Mol. Ther.  Aug;24(7):1290-30 2016.
  • Welbourn R, Dixon J, Barth JH, Finer N, Hughes CA, le Roux CW, Wass J; Guidance Development Group. NICE-Accredited Commissioning Guidance for Weight Assessment and Management Clinics: a Model for a Specialist Multidisciplinary Team Approach for People with Severe Obesity. Obes Surg. 2016 Jan 6. [Epub ahead of print] PMID: 26738895.
  • Welbourn R, le Roux CW, Owen-Smith A, Wordsworth S, Blazeby JM. Why the NHS should do more bariatric surgery; how much should we do? BMJ. 2016 May 11;353:i1472. doi: 10.1136/bmj.i1472. PMID: 27169605.
  • Wilding JP, Overgaard RV, Jacobsen LV, Jensen CB, le Roux CW. Exposure-response analyses of liraglutide 3.0 mg for weight management. Diabetes Obes Metab. 2016 Feb 2. doi: 10.1111/dom.12639. [Epub ahead of print] PMID: 26833744.
  • Zanchi D, Meyer-Gerspach AC, Suenderhauf C, Janach K, le Roux CW, Haller S, Drewe J, Beglinger C, Wölnerhanssen BK, Borgwardt S. Differential effects of L-tryptophan and L-leucine administration on brain resting state functional networks and plasma hormone levels. Sci Rep. 2016 Oct 20;6:35727.

 

2015

  • Chuah LL, Miras AD, Papamargaritis D, Jackson SN, Olbers T, le Roux CW. Impact of perioperative management of glycemia in severely obese diabetic patients undergoing gastric bypass surgery. Surg Obes Relat Dis. 2015 May-Jun;11(3):578-84. doi: 10.1016/j.soard.2014.11.004. Epub 2014 Nov 13. PMID: 25863535.
  • Abegg K, Corteville C, Docherty N.G, Boza C, Lutz T.A, Muñoz R, le Roux C.W. Effect of bariatric surgery combined with medical therapy versus intensive medical therapy or calorie restriction and weight loss on glycemic control in Zucker diabetic fatty rats. Am J Physiol Regul Integr Comp Physiol 15;308(4):R321-329. 2015.
  • Alsters SI, Goldstone AP, Buxton JL, Zekavati A, Sosinsky A, Yiorkas AM, Holder S, Klaber RE, Bridges N, van Haelst MM, le Roux CW, Walley AJ, Walters RG, Mueller M, Blakemore AI. Truncating Homozygous Mutation of Carboxypeptidase E (CPE) in a Morbidly Obese Female with Type 2 Diabetes Mellitus, Intellectual Disability and Hypogonadotrophic Hypogonadism. PLoS One. 2015 Jun 29;10(6):e0131417.
  • Arora T, Velagapudi V, Pournaras DJ, Welbourn R, le Roux CW, Orešič M, Bäckhed F. Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission. PLoS One. 2015 May 6;10 (5):e0126401. doi: 10.1371/journal.pone.0126401. eCollection 2015. PMID: 25946120.
  • Belgaumkar AP, Vincent RP, Carswell KA, Hughes RD, Alaghband-Zadeh J, Mitry RR, le Roux CW, Patel AG. Changes in Bile Acid Profile After Laparoscopic Sleeve Gastrectomy are Associated with Improvements in Metabolic Profile and Fatty Liver Disease. Obes Surg. 2015 Sep 4. [Epub ahead of print] PMID: 26337697.
  • Borgeson E, Johnston,A  Lee, YS, Till,A Syed, GH Ali Shah, T, Guiry PJ, Dalli, J Colas,R Serhan, CN, Sharma, K and Godson C.  Lipoxin A4 attenuates obesity-induced adipose inflammation and associated liver and kidney disease. Cell Metab. 2015 Jul 7;22(1):125-3.
  • Boxwell AJ, Chen Z, Mathes CM, Spector AC, le Roux CW, Travers SP, Travers JB. Effects of high-fat diet and gastric bypass on neurons in the caudal solitary nucleus. Physiol Behav. 2015 Dec 1;152(Pt B):329-39.
  • Breen C, Ryan M, Gibney MJ, O'Shea D. Diabetes-related nutrition knowledge and dietary intake among adults with type 2 diabetes. Br J Nutr. 2015 Aug 14;114(3):439-47.
  • Carolan E, Tobin LM, Mangan BA, Corrigan M, Gaoatswe G, Byrne G, Geoghegan J, Cody D, O'Connell J, Winter DC, Doherty DG, Lynch L, O'Shea D, Hogan AE. Altered distribution and increased IL-17 production by mucosal-associated invariant T cells in adult and childhood obesity  J Immunol. 2015 Jun 15;194(12):5775-80.
  • Crean D, Cummins EP, Bahar B, Mohan H, McMorrow JP, Murphy EP. 'Adenosine Modulates NR4A Orphan Nuclear Receptors to Attenuate Hyperinflammatory Responses in Monocytic Cells.' J Immunol. 2015; 195(4):1436-48.
  • de Gaetano M, Alghamdi K, Marcone S, Belton O. Conjugated linoleic acid induces an atheroprotective macrophage MΦ2 phenotype and limits foam cell formation. J Inflamm (Lond). 2015 Feb 19;12:15. doi: 10.1186/s12950-015-0060-9. eCollection 2015.
  • de Jonge C, Rensen SS, Verdam FJ, Vincent RP, Bloom SR, Buurman WA, le Roux CW, Bouvy ND, Greve JW. Impact of Duodenal-Jejunal Exclusion on Satiety Hormones. Obes Surg. 2015 Oct 7. [Epub ahead of print] PMID: 26446491.
  • Del Genio G, Gagner M, Limongelli P, Tolone S, Pournaras D, le Roux CW, Brusciano L, Licia Mozzillo A, Del Genio F, Docimo L. Remission of type 2 diabetes in patients undergoing biliointestinal bypass for morbid obesity: a new surgical treatment. Surg Obes Relat Dis. 2015 Dec 7. pii: S1550-7289(15)01093-X. doi: 10.1016/j.soard.2015.12.003. [Epub ahead of print] PMID: 27150339.
  • Di Francesco L, Dovizio M, Trenti A, Marcantoni E, Moore A, O'Gaora P, McCarthy C, Tacconelli S, Bruno A, Alberti S, Gizzo S, Nardelli GB, Orso G, Belton O, Trevisi L, Dixon DA, Patrignani P. Dysregulated post-transcriptional control of COX-2 gene expression in gestational diabetic endothelial cells. Br J Pharmacol. 2015 172(18): 4575-4587.
  • Elliott JA, Jackson S, King S, McHugh R, Docherty N.G, Reynolds J.V, le Roux C.W.  Gut Hormone Suppression Increases Food Intake After Esophagectomy With Gastric Conduit Reconstruction. Annals of Surgery 262: 824-829; discussion 829-830 2015.
  • Finucane OM, Lyons CL, Murphy AM, Reynolds CM, … Tierney AC, Morine MJ, Alcala-Diaz JF, Lopez-Miranda J, O'Connor DP, O'Neill LA, McGillicuddy FC, Roche HM. Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity. Diabetes. 64(6):2116-28, 2015.
  • Gaoatswe G, Kent BD, Corrigan MA, Nolan G, Hogan AE, McNicholas WT, O'Shea D. Invariant Natural Killer T Cell Deficiency and Functional Impairment in Sleep Apnea: Links to Cancer Comorbidity. Sleep. 2015 Oct 1;38(10):1629-34.
  • Goldstone AP, Miras AD, Scholtz S, Jackson S, Neff KJ, Pénicaud L, Geoghegan J, Chhina N, Durighel G, Bell JD, Meillon S, le Roux CW. Link between increased satiety gut hormones and reduced food reward following gastric bypass surgery for obesity. J Clin Endocrinol Metab. 2015 Nov 18:jc20152665. [Epub ahead of print] PMID: 26580235.
  • Jennings P, Crean D, Aschauer L, Limonciel A, Moenks K, Kern G, Hewitt P, Lhotta K, Lukas A, Wilmes A, Leonard MO. 'Interleukin-19 as a Translational Indicator of Renal Injury.' Arch Toxicol. 2015; 89(1):101-6.
  • Lavelle A, Lennon G, O'Sullivan O, Docherty N, Balfe A, Maguire A, Mulcahy H.E, Doherty G, O'Donoghue D, Hyland J, Ross R.P, Coffey J.C, Sheahan K, Cotter P.D, Shanahan F, Winter D.C, O'Connell PR. Spatial variation of the colonic microbiota in patients with ulcerative colitis and control volunteers. Gut. 64(10):1553-61.2015.
  • Locke AE, Genetic studies of body mass index yield new insights for obesity biology Nature. 2015 Feb 12;518(7538):197-206.
  • Maguire PJ, Power KA, O'Higgins AC, Jackson S, Harley R, le Roux CW, Turner MJ. Maternal C-reactive protein in early pregnancy. Eur J Obstet Gynecol Reprod Biol. 2015 Oct;193:79-82.
  • Marcantoni E, Dovizio M, O Gaora P, Di Francesco L, Bendaya I, Schiavone S, Trenti A, Guillem-Llobat P, Zambon A, Nardelli GB, Trevisi L, Patrignani P, Belton O  Dysregulation of gene expression in human fetal endothelial cells from gestational diabetes in response to TGF-β1. Prostaglandins Other Lipid Mediat. 2015 Mar 26.
  • Marcone S, Haughton K, Simpson PJ, Belton O, Fitzgerald DJ. Milk-derived bioactive peptides inhibit human endothelial-monocyte interactions via PPAR-γ dependent regulation of NF-κB.J Inflamm (Lond). 2015 Jan 20;12(1):1. doi: 10.1186/s12950-014-0044-1. eCollection 2015.PMID: 25632270.
  • Mathes CM, Bohnenkamp RA, Blonde GD, Letourneau C, Corteville C, Bueter M, Lutz TA, le Roux CW, Spector AC. Gastric bypass in rats does not decrease appetitive behavior towards sweet or fatty fluids despite blunting preferential intake of sugar and fat. Physiol Behav. 2015 Apr 1;142:179-88.
  • Mathes CM, Bohnenkamp RA, le Roux CW, Spector AC. Reduced sweet and fatty fluid intake after Roux-en-Y gastric bypass in rats is dependent on experience without change in stimulus motivational potency. Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15;309(8):R864-74.
  • McMorrow AM, Connaughton RM, Lithander FE, Roche HM. Adipose tissue dysregulation and metabolic consequences in childhood and adolescent obesity: potential impact of dietary fat quality. Proc Nutr Soc. 74(01):67-82, 2015.
  • Minihane AM, Vinoy S, Russell WR, Baka A, Roche HM, et al. Low-grade inflammation, diet composition and health: current research evidence and its translation. Br J Nutr. 114(07): 999-1012, 2015. DOI: 10.1017/S0007114515002093 (IF:3.311; C:31).
  • Miras AD, Chuah LL, Khalil N, Nicotra A, Vusirikala A, Baqai N, Graham C, Ravindra S, Lascaratos G, Oliver N, le Roux CW. Type 2 diabetes mellitus and microvascular complications 1 year after Roux-en-Y gastric bypass: a case-control study. Diabetologia. 2015 Jul;58(7):1443-7. doi: 10.1007/s00125-015-3595-7.
  • Murphy EP, Crean D. 'Molecular Interactions between NR4A Orphan Nuclear Receptors and NF-kappaB are Required for Appropriate Inflammatory Responses and Immune Cell Homeostasis.' Biomolecules. 2015; 5(3):1302-18.
  • Nolan KA, Brennan EP, Scholz CC, Cullen C, Ryan A, Taylor CT, Godson C*. Paricalcitol protects against TGF-β1-induced fibrotic responses in hypoxia and stabilises HIF-α in renal epithelia. Exp Cell Res. 2015 Jan 15;330(2):371-81.
  • O'Connor E, Green S, Kiely C, O'Shea D, Egaña M. Differential effects of age and type 2 diabetes on dynamic vs. peak response of pulmonary oxygen uptake during exercise. J Appl Physiol (1985). 2015 Apr 15;118(8):1031-9. PMID: 25701005.
  • Pi-Sunyer X, Astrup A, Fujioka K, Greenway F, Halpern A, Krempf M, Lau DC, le Roux CW, Violante Ortiz R, Jensen CB, Wilding JP; SCALE Obesity and Prediabetes NN8022-1839 Study Group. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. New England Journal Medicine. 2015 Jul 2;373(1):11-22.
  • Pournaras DJ, le Roux CW. Type 2 diabetes: multimodal treatment of a complex disease. Lancet. 2015 Sep 5;386(9997):936-7. doi: 10.1016/S0140-6736(15)00132-4.PMID: 2636945.
  • Quill B, Irnaten M, Docherty N.G, McElnea E.M, Wallace D.M, Clark A.F, O'Brien C.J. Calcium channel blockade reduces mechanical strain-induced extracellular matrix gene response in lamina cribrosa cells. Br J Ophthalmol. 99(7):1009-14 2015.
  • Risstad H, Søvik TT, Engström M, Aasheim ET, Fagerland MW, Olsén MF, Kristinsson JA, le Roux CW, Bøhmer T, Birkeland KI, Mala T, Olbers T. Five-year outcomes after laparoscopic gastric bypass and laparoscopic duodenal switch in patients with body mass index of 50 to 60: a randomized clinical trial. JAMA Surg. 2015 Apr;150(4):352-61.
  • Sam AH, Sleeth ML, Thomas EL, Ismail NA, Mat Daud N, Chambers E, Shojaee-Moradie F, Umpleby M, Goldstone AP, le Roux CW, Bech P, Busbridge M, Laurie R, Cuthbertson DJ, Buckley A, Ghatei MA, Bloom SR, Frost GS, Bell JD, Murphy KG. Circulating pancreatic polypeptide concentrations predict visceral and liver fat content. J Clin Endocrinol Metab. 2015 Mar;100(3):1048-52.
  • Sathyapalan T, Thatcher NJ, Hammersley R, Rigby AS, Courts FL, Pechlivanis A, Gooderham NJ, Holmes E, le Roux CW, Atkin SL. Aspartame sensitivity? A double blind randomised crossover study. PLoS One. 2015 Mar 18;10(3):e0116212. doi: 10.1371/journal.pone.0116212. eCollection 2015. Erratum in: PLoS One. 2015;10(5):e0126039.
  • Shungin D New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015 Feb 12;518(7538):187-96.
  • Somerville R, McKenzie K, Eslami S, Breen C, O'Shea D, Wall P. Poor mental health in severely obese patients is not explained by the presence of comorbidities. Clin Obes. 2015 Feb;5(1):12-21.
  • Spector AC, le Roux CW, Munger SD, Travers SP, Sclafani A, Mennella JA. Proceedings of the 2015 A.S.P.E.N. Research Workshop-Taste Signaling: Impact on Food Selection, Intake, and Health. JPEN J Parenter Enteral Nutr. 2015 Nov 23. pii: 0148607115617438. [Epub ahead of print] PMID: 26598504.
  • Todd JN, Dahlström EH, Salem RM, Sandholm N, Forsblom C; FinnDiane Study Group, McKnight AJ, Maxwell AP, Brennan E, Sadlier D, Godson C, Groop PH, Hirschhorn JN, Florez JC. Genetic Evidence for a Causal Role of Obesity in Diabetic Kidney Disease. Diabetes. 2015 Dec;64(12):4238-46.
  • Tremaroli V, Karlsson F, Werling M, Ståhlman M, Kovatcheva-Datchary P, Olbers T, Fändriks L, le Roux CW, Nielsen J, Bäckhed F. Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation. Cell Metab. 2015 Aug 4;22(2):228-38.
  • Werling M, Fändriks L, Olbers T, Bueter M, Sjöström L, Lönroth H, Wallenius V, Stenlöf K, le Roux CW. Roux-en-Y Gastric Bypass Surgery Increases Respiratory Quotient and Energy Expenditure during Food Intake. PLoS One. 2015 Jun 22;10(6):e0129784.
  • Wu Q, Li JV, Seyfried F, le Roux CW, Ashrafian H, Athanasiou T, Fenske W, Darzi A, Nicholson JK, Holmes E, Gooderham NJ. Metabolic phenotype-microRNA data fusion analysis of the systemic consequences of Roux-en-Y gastric bypass surgery. Int J Obes (Lond). 2015 Jul;39(7):1126-34.

 

2014

  • Ahern T, Khattak A, O'Malley E, Dunlevy C, Kilbane M, Woods C, McKenna MJ, O'Shea D. Association Between Vitamin D Status and Physical Function in the Severely Obese. J Clin Endocrinol Metab. 2014 Apr 15:jc20141704. 
  • Angelopoulos T, Kokkinos A, Liaskos C, Tentolouris N, Alexiadou K, Miras AD, Mourouzis I, Perrea D, Pantos C, Katsilambros N, Bloom SR, le Roux CW. The effect of slow spaced eating on hunger and satiety in overweight and obese patients with type 2 diabetes mellitus. BMJ Open Diabetes Res Care. 2014 Jul 2;2(1).
  • Bächler T, Schiesser M, Lutz TA, le Roux CW, Bueter M. Where to begin and where to end? Preoperative assessment for patients undergoing metabolic surgery. Dig Surg. 2014;31(1):25-32.
  • Bhutta HY, Deelman TE, le Roux CW, Ashley SW, Rhoads DB, Tavakkoli A. Intestinal sweet-sensing pathways and metabolic changes after Roux-en-Y gastric bypass surgery. Am J Physiol Gastrointest Liver Physiol. 2014 Sep 1;307(5):G588-93.
  • Breen C, Ryan M, McNulty B, Gibney MJ, Canavan R, O'Shea D. High saturated-fat and low-fibre intake: a comparative analysis of nutrient intake in individuals with and without type 2 diabetes. Nutr Diabetes. 2014 Feb 3;4:e104.
  • Carswell KA, Vincent RP, Belgaumkar AP, Sherwood RA, Amiel SA, Patel AG, le Roux CW. The effect of bariatric surgery on intestinal absorption and transit time. Obes Surg. 2014 May;24(5):796-805.
  • Elias E, Casselbrant A, Werling M, Abegg K, Vincent RP, Alaghband-Zadeh J, Olbers T, le Roux CW, Fändriks L, Wallenius V. Bone mineral density and expression of vitamin D receptor-dependent calcium uptake mechanisms in the proximal small intestine after bariatric surgery. Br J Surg. 2014 Nov;101(12):1566-75. doi: 10.1002/bjs.9626. Epub 2014 Sep 10.
  • Goyale A, Ashley SL, Taylor DR, Elnenaei MO, Alaghband-Zadeh J, Sherwood RA, le Roux CW, Vincent RP. Predicting refeeding hypophosphataemia: Insulin growth factor 1 (IGF-1) as a diagnostic biochemical marker for clinical practice. Ann Clin Biochem. 2014 Mar 7.
  • Hickey FB, Corcoran JB, Griffin B, Bhreathnach U, Mortiboys H, Reid HM, Andrews D, Byrne S, Furlong F, Martin F, Godson C*, Murphy M. IHG-1 increases mitochondrial fusion and bioenergetic function.  Diabetes. 2014 Dec;63(12):4314-25.
  • Jimenez-Gomez Y, Cruz-Teno C, Rangel-Zuñiga OA, Peinado JR, Perez-Martinez P, Delgado-Lista J, Garcia-Rios A, Camargo A, Vazquez-Martinez R, Ortega-Bellido M, Perez-Jimenez F, Roche HM, Malagon MM, Lopez-Miranda J. Effect of  dietary fat modification on subcutaneous white adipose tissue insulin sensitivity in patients with metabolic syndrome. Mol Nutr Food Res Nov;58(11):2177-88, 2014 .
  • Kim JY, Ha TK, le Roux CW. Metabolic effects of gastrectomy with or without omentectomy in gastric cancer. Hepatogastroenterology. 2014 Sep;61(134):1830-4.
  • Laurenius A, Werling M, Le Roux CW, Fändriks L, Olbers T. More symptoms but similar blood glucose curve after oral carbohydrate provocation in patients with a history of hypoglycemia-like symptoms compared to asymptomatic patients after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2014 Apr 18. pii: S1550-7289(14)00156-7. doi: 10.1016/j.soard.2014.04.007.
  • Lennon G, Balfe Á, Bambury N, Lavelle A, Maguire A, Docherty N.G, Coffey J.C, Winter D.C, Sheahan K, O'Connell PR. Correlations between colonic crypt mucin chemotype, inflammatory grade and Desulfovibrio species in ulcerative colitis. Colorectal Dis. 16(5):O161-169. 2014.
  • Lyons T, Neff KJ, Benn J, Chuah LL, le Roux CW, Gilchrist M. Body mass index and diabetes status do not affect postoperative infection rates after bariatric surgery. Surg Obes Relat Dis. 2014 Mar-Apr;10(2):291-7.
  • McAllan L, Skuse P, Cotter PD, O'Connor P, Cryan JF, Ross RP, Fitzgerald G,        Roche HM, Nilaweera, KN. Protein quality and the protein to carbohydrate ratio within a high fat diet influences energy balance and fatty acids and  polyphenols. Mol Nutr Food Res. 58(8):1708-1720, 2014.
  • McElnea E.M, Hughes E, McGoldrick A, McCann A, Quill B, Docherty N, Irnaten M,  Farrell M, Clark A.F, O'Brien C.J, Wallace D.M. Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells. BMC Ophthalmol. 14:153. 2014.
  • Miras AD, Al-Najim W, Jackson SN, McGirr J, Cotter L, Tharakan G, Vusirikala A, le Roux CW, Prechtl CG, Scholtz S. Psychological characteristics, eating behavior, and quality of life assessment of obese patients undergoing weight loss interventions. Scand J Surg. 2014 Jul 22.
  • Miras AD, Risstad H, Baqai N, Law S, Søvik TT, Mala T, Olbers T, Kristinsson JA, le Roux CW. Application of the International Diabetes Federation and American Diabetes Association criteria in the assessment of metabolic control after bariatric surgery. Diabetes Obes Metab. 2014 Jan;16(1):86-9.
  • Miras AD, Seyfried F, Phinikaridou A, Andia ME, Christakis I, Spector AC, Botnar RM, le Roux CW. Rats fed diets with different energy contribution from fat do not differ in adiposity. Obes Facts. 2014;7(5):302-10.
  • Neff KJ, Chuah LL, Aasheim ET, Jackson S, Dubb SS, Radhakrishnan ST, Sood AS, Olbers T, Godsland IF, Miras AD, le Roux CW. Beyond weight loss: evaluating the multiple benefits of bariatric surgery after Roux-en-Y gastric bypass and adjustable gastric band. Obes Surg. 2014 May;24(5):684-91.
  • Neff KJ, Prener C, Chuah LL, O'Donnell K, Godsland IF, Miras AD, le Roux CW. A holistic assessment of bariatric surgical outcomes in a Northern Irish cohort. Ir Med J. 2014 Jan;107(1):24-6.
  • O'Grada CM, Morine MJ, Morris C, Ryan M, Dillon ET, Walsh M, Gibney ER, Brennan L, Gibney MJ, Roche HM.  PBMCs reflect the immune component of the WAT transcriptome--implications as biomarkers of metabolic health in the postprandial state. Mol Nutr Food Res. 58(4):808-20, 2014.
  • Papamargaritis D, Aasheim ET, Sampson B, le Roux CW. Copper, selenium and zinc levels after bariatric surgery in patients recommended to take multivitamin-mineral supplementation. J Trace Elem Med Biol. 2014 Sep 16. pii: S0946-672X(14)00174-6.
  • Rodríguez-Peña A.B, Fuentes-Calvo I, Docherty N.G, Arévalo M, Grande M.T, Eleno N, Pérez-Barriocanal F, López-Novoa J.M. Effect of angiotensin II and small GTPase Ras signaling pathway inhibition on early renal changes in a murine model of obstructive nephropathy. Biomed Res Int. 2014:124902 2014.
  • Salinari S, le Roux CW, Bertuzzi A, Rubino F, Mingrone G. Duodenal-jejunal bypass and jejunectomy improve insulin sensitivity in Goto-Kakizaki diabetic rats without changes in incretins or insulin secretion. Diabetes. 2014 Mar;63(3):1069-78.
  • Scholtz S, Miras AD, Chhina N, Prechtl CG, Sleeth ML, Daud NM, Ismail NA, Durighel G, Ahmed AR, Olbers T, Vincent RP, Alaghband-Zadeh J, Ghatei MA, Waldman AD, Frost GS, Bell JD, le Roux CW, Goldstone AP. Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding. Gut. 2014 Jun;63(6):891-902.
  • Seyfried F, Bueter M, Spliethoff K, Miras AD, Abegg K, Lutz TA, le Roux CW. Roux-en Y Gastric Bypass Is Superior to Duodeno-Jejunal Bypass in Improving Glycaemic Control in Zucker Diabetic Fatty Rats. Obes Surg. 2014 Jun 15.
  • Tako AA, Kotiadis K, Vasilakis C, Miras A, le Roux CW. Improving patient waiting times: a simulation study of an obesity care service. BMJ Qual Saf. 2014 May;23(5):373-81.
  • Taylor DR, Alaghband-Zadeh J, Cross GF, Omar S, le Roux CW, Vincent RP. Urine bile acids relate to glucose control in patients with type 2 diabetes mellitus and a body mass index below 30 kg/m2. PLoS One. 2014 Apr 15;9(4):e93540.
  • Tobin AM, Hackett CB, Rogers S, Collins P, Richards HL, O'Shea D, Kirby B. Body Mass Index, Waist Circumference and HOMA-IR correlate with PASI in psoriasis patients receiving phototherapy. Br J Dermatol. 2014 Feb 23.
  • Tynan GA, Hearnden CH, Oleszycka E, Lyons CL, Coutts G, O'Connell J, Corrigan MA, Lynch L, Campbell M, Callanan JJ, Mok KH, Geoghegan J, O'Farrelly C, Allan SM, Roche HM, O'Shea DB, Lavelle EC. Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1α-dependent inflammation. Diabetes. 63(6):2037-50, 2014.
  • Werling M, Fändriks L, Royce VP, Cross GF, le Roux CW, Olbers T. Preoperative assessment of gut hormones does not correlate to weight loss after Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis. 2014 Sep-Oct;10(5):822-8.
  • Yang S, Wang B, Humphries F, Hogan AE, O'Shea D, Moynagh PN. The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance. Immunity. 2014 Dec 18;41(6):973-87.

2013

  • Brennan EP, Nolan KA, Borgeson E,  Gough OS, McEvoy C, Docherty NG, Higgins DF, Murphy M, Sadlier DM,Ali-Shah T, Guiry PJ, The GENIE Consortium, Savage D, Maxwell AP, Martin F, Godson C* Lipoxins attenuate renal fibrosis by induction of let-7c and suppression of TGFβR1 J Am Soc Nephrol 2013, 24(4):627-37.
  • Briggs AD, Mytton OT, Madden D, O'Shea D, Rayner M, Scarborough P. The potential impact on obesity of a 10% tax on sugar-sweetened beverages in Ireland, an effect assessment modelling study. BMC Public Health. 2013 Sep 17;13:860.
  • Carolan E, Hogan AE, Corrigan M, Gaotswe G, O'Connell J, Foley N, O'Neill LA, Cody D, O'Shea D. The impact of childhood obesity on inflammation, innate immune cell frequency and metabolic microRNA expression. J Clin Endocrinol Metab. 2013 Jan 1.
  • Cohen R, le Roux CW, Papamargaritis D, Salles JE, Petry T, Correa JL, Pournaras DJ, Galvao Neto M, Martins B, Sakai P, Schiavon CA, Sorli C. Role of proximal gut exclusion from food on glucose homeostasis in patients with Type 2 diabetes. Diabet Med. 2013 Jun 26. doi: 10.1111/dme.12268.
  • de Gaetano M, Dempsey E, Marcone S, James WG, Belton O. Conjugated linoleic acid targets β2 integrin expression to suppress monocyte adhesion. J Immunol. 2013 Oct 15;191(8):4326-36.
  • de Jonge C, Rensen SS, Verdam FJ, Vincent RP, Bloom SR, Buurman WA, le Roux CW, Schaper NC, Bouvy ND, Greve JW. Endoscopic duodenal-jejunal bypass liner rapidly improves type 2 diabetes. Obes Surg. 2013 Sep;23(9):1354-60.
  • Faherty, N., O’Donovan, H.C., Kavanagh, D., Madden, S., McKay, G.J., Maxwell, A.P., Martin, F., Godson, C. and Crean, J. TGF-beta and CCN2/CTGF mediate actin related gene expression by differential E2F1/CREB activation. BMC Genomics 2013, 14:525  doi:10.1186/1471-2164-14-525.
  • Hogan AE, Gaoatswe G, Lynch L, Corrigan MA, Woods C, O'Connell J, O'Shea D. Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus. Diabetologia. 2013 Dec 21.
  • Irnaten M, Barry R.C, Wallace D.M, Docherty N.G, Quill B, Clark A.F, O'Brien C.J. Elevated maxi-K(+) ion channel current in glaucomatous lamina cribrosa cells. Exp Eye Res. 115C:224-229. 2013
  • Kavanagh, D., Savage, D.A., Patterson, C., McKnight, A.J., Crean, J., Alexander P Maxwell, A.P.,  McKay, G.J. Haplotype association analysis of genes within the WNT signalling pathways indiabetic nephropathy BMC Nephrology 2013, 14:126.
  • Lynch, J., Meehan, M.H., Crean, J., Copeland, J., Stallings, R.L., Bray, I.M. Metastasis Suppressor microRNA-335 Targets the Formin Family of Actin Nucleators. PLoS One. 2013 Nov 5;8(11).
  • McArdle MA, Finucane OM, Connaughton RM, McMorrow AM, Roche HM. Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies. Front. Endocrinol 4, 52, 2013.
  • McCarthy C, Duffy MM, Mooney D, James WG, Griffin MD, Fitzgerald DJ, Belton O. IL-10 mediates the immunoregulatory response in conjugated linoleic acid-induced regression of atherosclerosis. FASEB J. 2013 Feb;27(2):499-510.
  •  McCarthy C, Lieggi NT, Barry D, Mooney D, de Gaetano M, James WG, McClelland S, Barry MC, Escoubet-Lozach L, Li AC, Glass CK, Fitzgerald DJ, Belton O Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid. EMBO Mol Med. 2013 Sep;5(9):1443-57.
  • O'Shea D, Corrigan M, Dunne MR, Jackson R, Woods C, Gaoatswe G, Moynagh PN, O'Connell J, Hogan AE. Changes in human dendritic cell number and function in severe obesity may contribute to increased susceptibility to viral infection Int J Obes (Lond). 2013 Feb.
  • Osto M, Abegg K, Bueter M, le Roux CW, Cani PD, Lutz TA. Roux-en-Y gastric bypass surgery in rats alters gut microbiota profile along the intestine. Physiol Behav. 2013 Jul 2;119:92-6.
  • Phillips CM, Tierney AC, Perez-Martinez P, Defoort C, Blaak EE, Gjelstad IMF, Lopez-Miranda J, Kiec-Klimczak M, Malczewska-Malec M, Drevon CA, Hall W, Lovegrove JA, Karlstrom B, Risérus U, Roche HM. Obesity and body fat classification in the metabolic syndrome: Impact on cardiometabolic risk metabotype.  Obesity 21 (1): E154-E161, 2013.
  • Pournaras DJ, le Roux CW. Are bile acids the new gut hormones? Lessons from weight loss surgery models. Endocrinology. 2013 Jul;154(7):2255-6.
  • Sam AH, Busbridge M, Amin A, Webber L, White D, Franks S, Martin NM, Sleeth M, Ismail NA, Daud NM, Papamargaritis D, le Roux CW, Chapman RS, Frost G, Bloom SR, Murphy KG. Hepcidin levels in diabetes mellitus and polycystic ovary syndrome. Diabet Med. 2013 Jun 24. doi: 10.1111/dme.12262.
  • Seyfried F, Miras AD, Bueter M, Prechtl CG, Spector AC, le Roux CW. Effects of preoperative exposure to a high-fat versus a low-fat diet on ingestive behavior after gastric bypass surgery in rats. Surg Endosc. 2013 Nov;27(11):4192-201.

View my collection, "Diabetes Complications Research Centre" from NCBI