Based in the Health Science Centre in UCD, we are a strong translational research group, specialising in cellular microbiology and the study of pathogen interactions. We have worked for a long time with the gastrointestinal pathogens Helicobacter pylori and Campylobacter jejuni and more recently we have started to work also with Pseudomonas aeruginosa an opportunistic pathogen that is a particular problem for individuals with cystic fibrosis.
Our area of interest is how bacteria interact with human and animal tissue and cause disease. An area of particular interest is how bacteria colonise and live in mucus. We have developed a number of novel systems to learn how bacteria colonise mucus and interact with different components of mucus. Such knowledge can lead to the development of new therapeutics that can prevent infection as alternatives to antibiotics.
|Location: UCD Health Sciences Centre|
|Director: Dr Marguerite Clyne|
|Tel: 01 7166619|
Three projects that we are currently involved in are:
My research investigates how pathogens such as Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa colonise the gut and the lung. I am involved in an inter-institutional, multidisciplinary consortium of academic and industrial researchers funded by Science Foundation Ireland aimed at understanding the glycobiology of human intestinal infections. I am also funded by the Cystic Fibrosis Association of Ireland and the Health Research Board to investigate how P. aeruginosa colonises and maintains infection in the lung.