Dr Marion Rowland MB., BCh., BAO., MPH., PhD
Marion Rowland graduated from Medical School at the National University of Ireland Galway in 1979 (MB, BCh, BAO). Following graduation she spent 2 years in Internship/ Residency postgraduate training in Ireland, involving rotations in General/Internal Medicine, General Surgery, Obstetrics and Gynecology and Pediatrics.
Subsequently she worked in Nigeria as a Medical Officer for over 2 years providing Medical, Pediatric and Obstetric care, in a 200-bed hospital in a densely populated area of Cross River State. Between 1985 and 1989 she provided long-term family practice/ general practitioner locum cover in isolated, mainly Native Indian communities across several provinces in Canada.
On returning to Ireland Dr Rowland completed a Masters in Public Health at University College Dublin, following which she began her career in Epidemiology. She subsequently completed a PhD [Epidemiology] under the supervision of Prof. Leslie Daly at UCD.
For the past 15 years she has been a Clinical Epidemiologist at the School of Medicine and Medical Science at UCD with a special interest in research on pediatric gastrointestinal diseases. Her work has been published on several occasions in the highest impact journals in both Gastroenterology and Pediatrics. She has twice been an invited editorial/commentary provider to the Lancet. She won the overall award for the best research publication from an Irish university at the annual Royal Academy of Medicine of Ireland/IJMS Awards. This award was based on her research on the epidemiology of Helicobacter pylori.
In 2010-11 Dr Rowland worked in the Directorate of Quality and Clinical Care of Health Service Executive to develop a quality improvement/comparative effectiveness research protocols for the chronic disease programs. As part of this project she provided the clinical research support to optimize scheduling of outpatient appointments and investigations using constraint optimization in collaboration with Cork Constraint Computation Centre (4C). An important outcome of this work was to demonstrate that there was significant underutilization of resources which could be much more effectively utilized if new models of scheduling were introduced for appointments and staff rosters.
Dr. Rowland is currently a board member of the Health Research Board, which is the national agency responsible for developing clinical research capacity in Ireland and funding clinical research.
She also maintains her interest in the developing world through her involvement with a number of nongovernmental organizations.
Epidemiological studies, which provide large cohorts of well-characterized participants, are a key platform to enable the translation of new technologies and laboratory techniques into real advances in patient care. As an island nation I believe we have a unique opportunity to contribute to future advances in translational research in a number of areas. My research has focused on long-term epidemiological studies, which seek to increase our understanding of the disease process/phenotype in the areas of Cystic Fibrosis, Helicobacter pylori, and Functional Disorders in Children.
Cystic Fibrosis [CF] is the commonest life-shortening inherited disease of Caucasians. Our research interest is in cystic fibrosis liver disease, which affects 10% of children with CF. We are attempting to identify the risk factors for severe liver disease because of its associated reduced life expectancy. Following on from our earlier studies we are now undertaking a long-term national study of all children with CF in Ireland to characterize the different phenotypes in CF liver disease and to provide a better understanding of the disease process as we search for new therapeutic options. This requires close collaboration with our clinical colleagues across Ireland who provide care for patients with CF.
Helicobacter pylori (H. pylori) causes peptic ulcer disease, which in the past resulted in 20% of all acute hospital admissions. H. pylori is also a risk factor for stomach cancer. Our studies on H. pylori which have been funded by The Wellcome Trust (UK) and the Health Research Board (Ireland) have focused on the prevalence and transmission of infection among families. These studies depend on the co-operation of a network of dedicated family/general practitioners throughout Ireland. The results of these studies have been published on number of occasions in Gastroenterology, the highest-ranking international gastroenterology journal.
Functional Disorders in Children
I lead and collaborate with studies in the area of cyclical vomiting (CVS) and functional abdominal pain in children. The Irish Pediatric Surveillance Unit provided us with a unique opportunity to examine the incidence of CVS, which is considered to be a rare condition in children. Using well-defined criteria for CVS with the IPSU format of monthly surveys of Pediatricians we found that CVS is a relatively common and very distressing condition for children and their families. In raising awareness of CVS among pediatricians nationally we believe that we have also improved the management and outcome of CVS for children in Ireland. We are now engaged in clinical studies on the natural history of CVS with Professor Billy Bourke the pediatric gastroenterologists.
Providing a research support to liaison psychiatry and pediatric gastroenterology we helped identify the key factors in the successful management of functional abdominal pain in children.
I believe it is a responsibility for clinical epidemiologists to support clinicians who are undertaking clinical research projects in their own area. It is often difficult for young clinicians to initiate research because of the challenges involved in study design and analysis of data. This has resulted in my involvement in projects across a wide range of specialties varying from oral Crohns disease, dermatology to colorectal surgery.
| Sponsor : Health Research Board (HRB)
Title : The Natural History of Cystic Fibrosis Liver Disease- Refining the Phenotype
Start Date / End Date : 06-OCT-14 / 04-JAN-18
| Sponsor : Health Research Board (HRB)
Title : An evaluation of Helicobacter pylori prevalence and strain diversity in a unique cohort of adolescents in a developed country
Start Date / End Date : 01-NOV-12 / 31-OCT-15
| Sponsor : Health Research Board (HRB)
Title : The Natural History of Cystic Fibrosis Liver Disease
Start Date / End Date : 06-APR-11 / 06-OCT-14
| Sponsor : Health Research Board (HRB)
Title : The Natural History of Cystic Fibrosis Liver Disease - A Ten Year Follow-Up Study
Start Date / End Date : 07-JUN-10 / 06-AUG-10
|Rowland M, Bourke B, Drumm B (2008) 'Helicobacter pylori and peptic ulcer disease' In: Walker, WA. Goulet, O. Kleinman, RE. Sherman, PM. Shneider, BL. Sanderson, IR (eds). Pediatric Gastrointestinal Disease Pathophysiology, Diagnosis Management. Hamilton: BC Decker Hamilton. [Details]|
|Rowland M, Bourke B, Drumm B (2000) 'Gastritis and Peptic Ulcer Disease' In: Walker, WA. Durie, PR. Hamilton, JR. Walker-Smith JA. Watkins JB (eds). Pediatric Gastrointestinal Disease Pathophysiology, Diagnosis Management. St Louis: Mosby. , pp.383-404 [Details]|
|Rowland M, Drumm B (1996) 'Helicobacter pylori infection in children In Helicobcater pylori' In: Hunt, RH Tytgat, GNJ (eds). Basic Mechanisms to Clinical Cure. Dordrecht: Kluwer Academic Publications. , pp.286-294 [Details]|
Peer Reviewed Journals
|Rowland, M. and Gallagher, C. and Gallagher, C.G. and Laoide, R.T. and Canny, G. and Broderick, A.M. and Drummond, J. and Greally, P. and Slattery, D. and Daly, L. and McElvaney, N.G. and Bourke, B. (2015) 'Outcome in patients with cystic fibrosis liver disease'. Journal of Cystic Fibrosis, 14 (1):120-126. [DOI] [Details]|
|Hirsch C, Tegtmeyer N, Rohde M, Rowland M, Oyarzabal OA, Backert S. (2012) 'Live Helicobacter pylori in the root canal of endodontic-infected deciduous teeth'. Journal of gastroenterology, 47 (8). [Details]|
|Drumm BR, Bourke B, Drummond J, McNicholas F, Quinn S, Broderick A, Taaffe S, Twomey J, Rowland M (2012) 'Cyclic vomiting syndrome in children:A prospective study'. Neurogastroenterology and Motility, . [Details]|
|Brett, T,Rowland, M,Drumm, B (2012) 'An approach to functional abdominal pain in children and adolescents'. British Journal of General Practice, 62 :386-387. [DOI] [Details]|
|Hussey S, Fleming P, Rowland M, Harty S, Chan L, Broderick A, Drumm B, Bourke B (2011) 'Disease outcome for children who present with oral manifestations of Crohn's disease'. European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 12 (3):167-169. [Details]|
|Sykora J, Rowland M; (2011) 'Helicobacter pylori in Pediatrics'. Helicobacter, Supp1 :59-64. [Details]|
|Drumm B, Rowland M; (2011) 'Why is Helicobacter pylori disappearing? More questions than answers'. Jornal de pediatria, 87 (5):369-370. [DOI] [Details]|
|Koletzko S, Jones NL, Goodman KJ, Gold B, Rowland M, Cadranel S, Chong S, Colletti RB, Casswall T, Elitsur Y, Guarner J, Kalach N, Madrazo A, Megraud F, Oderda G; (2011) 'Evidence-based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection in children'. Journal of pediatric gastroenterology and nutrition, 53 (2):230-243. [DOI] [Details]|
|Kezic S, O'Regan GM, Yau N, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, McLean WH, Irvine AD; (2011) 'Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity'. Allergy, 66 (7):934-940. [DOI] [Details]|
|Rowland M, Bourke B. ; (2011) 'Liver disease in cystic fibrosis'. Current Opinion in Pulmonary Medicine, 17 :461-466. [Details]|
|O'Regan GM, Kemperman PM, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Rowland M, Puppels GJ, McLean WH, Caspers PJ, Irvine AD; (2010) 'Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes'. Clinical Immunology, 126 (3):574-800. [DOI] [Details]|
|Rowland M, Fleming P, Bourke B; (2010) 'Looking in the mouth for Crohn's disease'. Inflammatory bowel diseases, 16 :332-337. [DOI] [Details]|
|1. Rowland M, Gallagher CG, O'Laoide R, Canny G, Broderick A, Hayes R, Greally P, Slattery D, Daly L, Durie P, Bourke B; (2010) 'Outcome in cystic fibrosis liver disease'. American Journal of Gastroenterology, 106 (1):104-109. [Details]|
|Bartlett, JR,Friedman, KJ,Ling, SC,Pace, RG,Bell, SC,Bourke, B,Castaldo, G,Castellani, C,Cipolli, M,Colombo, C,Colombo, JL,Debray, D,Fernandez, A,Lacaille, F,Macek, M,Rowland, M,Salvatore, F,Taylor, CJ,Wainwright, C,Wilschanski, M,Zemkova, D,Hannah, WB,Phillips, MJ,Corey, M,Zielenski, J,Dorfman, R,Wang, YF,Zou, F,Silverman, LM,Drumm, ML,Wright, FA,Lange, EM,Durie, PR,Knowles, MR,Gene Modifier Study Grp; (2009) 'Genetic Modifiers of Liver Disease in Cystic Fibrosis'. JAMA-Journal of the American Medical Association, 302 :1076-1083. [Details]|
|Fitzpatrick, E,Bourke, B,Drumm, B,Rowland, M; (2008) 'The incidence of cyclic vomiting syndrome in children: Population-based study'. American Journal of Gastroenterology, 103 :991-995. [DOI] [Details]|
|Brennan DJ , Moynagh M , Brannigan AE , Gleeson F , Rowland M , O'Connell PR; (2007) 'Routine mobilization of the splenic flexure is not necessary during anterior resection for rectal cancer'. Diseases of the Colon and Rectum, 50 :302-307. [Details]|
|Rowland M, Fitzpatrick E, Bourke B, Drumm B, ; (2007) 'Outcome for children with cyclical vomiting syndrome'. Archives of Disease in Childhood, 92 (11):1001-1004. [DOI] [Details]|
|Rowland, M,Daly, L,Vaughan, M,Higgins, A,Bourke, B,Drumm, B; (2006) 'Age-Specific incidence of Helicobacter pylori'. GASTROENTEROLOGY, 130 (NA):65-72. [DOI] [Details]|
|Finn SM, Rowland M, Lawlor F, Kinsella W, Chan L, Byrne O, O'Mahony O, Bourke B. ; (2006) 'The significance of cutaneous spider naevi in children'. Archives of Disease in Childhood, 91 (7):604-605. [Details]|
|Rowland M, Broderick A, Bourke B. ; (2006) 'Behavioral and nutritional treatment to improve energy intake and growth in toddlers and preschool-aged children with cystic fibrosis'. Paediatrics, 118 (1):432-433. [Details]|
|Harty S, Fleming P, Rowland M, Crushell E, McDermott M, Drumm B, Bourke B. ; (2005) 'A prospective study of the oral manifestations of Crohns disease'. Clinical Gastroenterology and Hepatology, 3 :886-891. [Details]|
|Rowland, M.,Bourke, B.,Drumm, B.; (2005) 'Do the Rome criteria help the doctor or the patient?'. J Pediatr Gastroenterol Nutr, 41 Suppl 1 :S32-3. [Details]|
|Corbett K, Kelleher S, Rowland M, Daly L, Drumm B, Canny G, Greally P, Hayes R, Bourke B.; (2004) 'Cystic fibrosis-associated liver disease: A population-based study'. Journal of Paediatrics, 145 :327-332. [Details]|
|Crushell E, Rowland M, Doherty M, Gormally S, Harty S, Bourke B, Drumm B. ; (2003) 'Importance of parental conceptual model of illness in severe recurrent abdominal pain'. Paediatrics, (112):1368-1372. [Details]|
|Sharif F, McDermott M, Dillon M, Rowland M, Kelleher S, Drumm B, Bourke B. ; (2002) 'Focally enhanced gastritis in Crohn disease and ulcerative colitis'. American Journal of Gastroenterology, 97 :1415-1420. [Details]|
|Drumm B, Imrie C, Rowland M, Bourke B, ; (2001) 'Is Helicobacter pylori infection in childhood a risk factor for gastric cancer?'. Pediatrics, 107 (2):373-380. [Details]|
|Rowland, M; Drumm, B; ; (2001) 'Helicobacter pylori and sudden-infant-death syndrome'. Lancet, 357 (9253):327-327. [Details]|
|Imrie, C; Rowland, M; Bourke, B; Drumm, B; ; (2001) 'Limitations to carbon 13-labeled urea breath testing for Helicobacter pylori in infants'. Pediatrics, 139 (5):734-737. [Details]|
|Rowland M, Kumar D, Daly L, O'Connor P, Vaughan D, Drumm B.; (1999) 'Low rates of Helicobacter pylori reinfection in children'. Gastroenterology, 117 :336-341. [Details]|
|Drumm B, Rowland M, Imrie C, Bourke B, ; (1999) 'How should Helicobacter pylori infected children be managed?'. Gut, 45 Suppl 1 (NA):1-9. [Details]|
|Rowland, M,Drumm, B; (1998) 'Clinical significance of Helicobacter infection in children'. British Medical Bulletin, 54 :95-103. [Details]|
|Rowland, M; Lambert, I; Gormally, S; Daly, LE; Thomas, JE; Hetherington, C; Durnin, M; Drumm, B; ; (1998) 'C-13 urea breath test for the diagnosis of Helicobacter pylori in children'. Gut, 43 (NA):8-8. [Details]|
|Rowland M, Kumar D, O'Connor P, Daly LE, Drumm B. ; (1997) 'Reinfection with Helicobacter pylori in children'. GUT, 41 (NA):33-33. [Details]|
|Rowland, M, Lambert, I, Gormally, S, Daly, LE, Thomas, JE, Hetherington, C, Durnin, M, Drumm, B, ; (1997) 'Carbon 13 - Labeled urea breath test for the diagnosis of Helicobacter pylori infection in children'. Pediatrics, 131 (6):815-820. [Details]|
|Rowland, M; Kumar, D; OConnor, P; Daly, LE; Drumm, B; ; (1997) 'Reinfection with Helicobacter pylori in children'. Gastroenterology, 112 (4):273-273. [Details]|
|Sharif, F., McDermott, M., Dillon, M., Rowland, M., Kelleher, S., Drumm, B., and Bourke, B.; (0) 'Focally enhanced gastritis in Crohn disease and ulcerative colitis'. American Journal of Gastroenterology, . [Details]|
|Finn, S.M., Rowland, M., Lawlor, F., Kinsella, W., Chan, L., Byrne, O., O'Mahony, O. Bourke, B.; (2006) 'The significance of cutaneous spider maevi in children' Arch Dis Child . [Details]|
|Harty, S., Fleming, P., Rowland, M., Crushell, E., McDermott, M., Drumm, B., Bourke, B.; (2005) 'A prospective study of the oral manifestations of Crohn's disease' Clin Gastroenterol Hepatol . [Details]|
|Harty, S., Fleming, P., Rowland, M., Crushell, E., McDermott, M., Drumm, B., Bourke, B.; (2005) 'A prospective stidy of the oral manifestations of Crohn's disease' Clin Gastroenterol Hepatol . [Details]|
|Brennan, DJ,Moynagh, M,Brannigan, AE,Gleeson, F,Rowland, M,O'Connell, PR (2007) DISEASES OF THE COLON & RECTUM Routine mobilization of the splenic flexure is not necessary during anterior resection for rectal cancer , pp.302-307 [DOI] [Details]|
|Rowland, M,Bourke, B,Drumm, B (2005) JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION Functional abdominal pain - Do the Rome criteria help the doctor or the patient? , pp.32-33 [Details]|
|Rowland, M,Imrie, C,Bourke, B,Drumm, B (1999) GUT How should Helicobacter pylori infected children be managed? , pp.36-39 [Details]|
|Drumm, B,Rowland, M; (2003) The epidemiology of Helicobacter pylori: Where to from here?. Editorial [Details]|
|Rowland, M,Drumm, B; (2001) Helicobacter pylori and sudden-infant-death syndrome. Editorial [Details]|
|Drumm, B,Bourke, B,McNicholas, F,Broderick, A,Quinn, S,Drummond, J,Rowland, M (2011) CYCLICAL VOMITING SYNDROME, A PROSPECTIVE STUDY. Abstract [Details]|
|Barnes, F,Rowland, M,Watt, P (2011) THE HIGH FREQUENCY CHEST COMPRESSION (HFCC) VEST AS A COMPLEMENTARY INTERVENTION IN PERSONS WITH CYSTIC FIBROSIS WHO FIND IT DIFFICULT TO ENGAGE IN EFFECTIVE EXERCISE OR PHYSIOTHERAPY. Abstract [Details]|
|Clegg, M,Shafat, A,Dobson, M,Rowland, M (2007) The effect of lactulose and inulin on gastric emptying in men. Abstract [Details]|
|Rowland, M,Lambert, I,Gormally, S,Daly, LE,Thomas, JE,Hetherington, C,Durnin, M,Drumm, B (1998) C-13 urea breath test for the diagnosis of Helicobacter pylori in children. Abstract [Details]|
|Rowland, M,Kumar, D,OConnor, P,Daly, LE,Drumm, B (1997) Reinfection with Helicobacter pylori in children. Abstract [Details]|
|Imrie, C,Rowland, M,Bourke, B,Drumm, B (2001) Is Helicobacter pylori infection in childhood a risk factor for gastric cancer?. Reviews [Details]|
|Rowland, M,Broderick, A,Bourke, B (2006) Behavioral and nutritional treatment to improve energy intake and growth in toddlers and preschool-aged children with cystic fibrosis. Letters [DOI] [Details]|
|Bourke, B,Rowland, M (2006) Pulmonary prognosis in cystic fibrosis patients with liver disease - Reply. Letters [DOI] [Details]|
|Crushell, E,Rowland, M (2005) Biopsychosocial approach to functional abdominal pain. Letters [Details]|
|Drumm, B,Rowland, M,Imrie, C (1999) Sensitivity of urease-based test on diagnosis of Helicobacter pylori in children and the elderly. Letters [Details]|
|Fitzpatrick E, Sherlock M, Drumm B, Rowland M.; The incidence of cyclic vomiting syndrome in the pediatric population in Ireland. [Other], Presented to the Neurogastroenterology & Motility 2006 Joint International Meeting, Boston, MA .|