My One Health PhD project focused on human triple negative breast cancer and feline mammary adenocarcinoma. These cancers are extremely aggressive and are associated with poorer outcomes for patients, compared to other types of breast cancer. In collaboration with clinicians in MMUH and SVUH, I collected blood samples from patients who had been diagnosed with this invasive triple negative breast cancer. Similarly, in collaboration with vets across Ireland, blood samples were collected from feline patients with mammary cancer. I analysed nanoparticles called extracellular vesicles from these blood samples. Using lab-based techniques, I discovered that these nanoparticles can potentially distinguish patients with cancer from healthy individuals. For the first time, we demonstrated the similarities between breast cancer in humans and mammary cancer in felines. We also showed that comparative research approaches can potentially benefit both humans and animals concurrently.
The highlights of my experience as a PhD student include the exhilarating achievement of being the leading author in my inaugural publication. I also had the privilege to present my work at numerous national and international conferences around Ireland and abroad. Through these opportunities, I could both disseminate my research findings and cultivate valuable professional relationships, which played a pivotal role in my personal and academic development. Additionally, I enjoyed taking part in the many scientific communication opportunities. Taking part in UCD’s ThesisIn3 competition was a particularly enjoyable experience.
While it is important to choose a topic that you are passionate about, I also believe it is crucial to select an environment in which you can grow and develop as an independent researcher. As PhD students, we are unique, so finding a supportive supervisor and research group that aligns with your working style is very important. Additionally, I would strongly encourage students to maintain the hobbies they had before starting the program, as having an outlet unrelated to your research can be a lifesaver during more stressful times. Similarly, it's important to enjoy the social aspects that come with being a PhD student. Balancing hard work and enjoyable downtime is key to the success and well-being of a PhD student.
I thoroughly enjoyed my time as a PhD student in UCD. The opportunities to form collaborations with various University Hospitals and UCD schools, fostered a multidisciplinary approach to my research project. Additionally, UCD's extensive expertise and resources greatly supported my PhD project. Prof. Amanda McCann and Dr. Pamela Kelly provided invaluable supervision throughout my project and also importantly encouraged my growth as an independent researcher. UCD also offered professional development opportunities through courses and modules which have been a huge help to me as I continue to navigate continuing my research career. Most importantly, the PhD journey allowed me to form lasting friendships with fellow students. These were crucial for my everyday contentment but also enhanced my overall experience.
Visit Jane's Orcid profile here.