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Publication List

Our 2025 list of publications include articles produced by our cluster's researchers as well as publications arising from the hard work of our trial units at St Vincent's University Hospital and The Mater Misericordiae University Hospital.

  • Aceituno, L., Gravely, A. K., O'Kane, G. M., Vogel, A., & Sapisochin, G. (2025). The use of immunotherapy pre-liver transplant. Journal of hepatology, 82(4), 757–759. https://doi.org/10.1016/j.jhep.2024.11.005
  • Beaudry, F. E. G., Li, Z., Borgida, A., Zorigtbaatar, A., Wang, X., Hildebrand, M., Hamza, O., Jang, G. H., Bucur, R., Dodd, A., Wilson, J., Auer, R. C., Saibil, S., Tsang, E. S., Vogel, A., O'Kane, G. M., Gallinger, S., Knox, J. J., Notta, F., Sapisochin, G., … Grant, R. C. (2025). Molecular Tumor Board-Guided Targeted Treatments for Biliary Tract Cancers in a Publicly Funded Healthcare System. Current oncology (Toronto, Ont.), 32(2), 80. https://doi.org/10.3390/curroncol32020080
  • Blasco, A., López-Tarruella, S., Urruticoechea, A., Carrasco, E., Spera, G., Martín, M., Bermejo, B., Chap, L., Ruiz-Borrego, M., Crown, J., García-Saenz, J. A., Chan, A., Guerrero-Zotano, Á., Semiglazov, V., Calvo, L., Pienkowski, T., Herranz, J., & Slamon, D. (2025). Intermediate endpoints as surrogates for long-term outcomes in breast cancer adjuvant chemotherapy trials. The oncologist, 30(9), oyaf263. https://doi.org/10.1093/oncolo/oyaf263
  • Bredin, P., Galvin, Z., & O'Kane, G. M. (2025). Role of immunotherapy in managing cancers prior to liver transplantation. Current opinion in organ transplantation, 30(1), 3–11. https://doi.org/10.1097/MOT.0000000000001187
  • Burke, C., Glynn, T., Jahangir, C., Murphy, C., Buckley, N., Tangney, M., Rahman, A., & Gallagher, W. M. (2025). Exploring the prognostic and predictive potential of bacterial biomarkers in non-gastrointestinal solid tumors. Expert review of molecular diagnostics, 25(4), 117–128. https://doi.org/10.1080/14737159.2025.2465743
  • Carroll, G., Sweeney, F. F., Meaney, C., DeFrein, A. M., Higgins, M. J., Keane, M. M., Hayat, A., & Heckmann, P. (2025). Improving cancer care through electronic libraries: A survey of health professionals' experiences with Ireland's systemic anti-cancer therapy regimen library. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 10781552251367356. Advance online publication. https://doi.org/10.1177/10781552251367356
  • Choi, W. J., Ivanics, T., Claasen, M., Magyar, C. T. J., Li, Z., Tabrizian, P., Rocha, C., Myers, B., O'Kane, G. M., Reig, M., Ferrer Fàbrega, J., Holgin, V., Parikh, N. D., Pillai, A., Hunold, T. M., Vogel, A., Patel, M. S., Singal, A. G., Tadros, M., Feld, J. J., … Sapisochin, G. (2025). Direct-acting antivirals lower mortality and recurrence in HCV-related hepatocellular carcinoma post liver resection: A multicenter international study. Surgery, 183, 109396. https://doi.org/10.1016/j.surg.2025.109396
  • Conduit, C., Inderjeeth, A. J., Allen, R., Martin, A. J., Parulekar, W., Mulroe, E., McJannett, M., Zielinski, R. R., Thomson, A., Tan, T. H., Sandhu, S. K., Reaume, M. N., Pook, D. W., North, S. A., Marx, G. M., Joshua, A., Horvath, L., McDermott, R., Chowdhury, S., Chi, K. N., … ANZUP Cancer Trials Group (2025). Enzalutamide with standard first-line therapy for metastatic hormone-sensitive prostate cancer: a plain language summary of the ENZAMET trial (ANZUP 1304). Future oncology (London, England), 21(6), 627–636. https://doi.org/10.1080/14796694.2024.2440277
  • Corcoran, C., Rani, S., Breslin, S., Gogarty, M., Ghobrial, I. M., Crown, J., & O'Driscoll, L. (2025). Correction: miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer. Molecular cancer, 24(1), 37. https://doi.org/10.1186/s12943-025-02251-8
  • Crown, J., Eustace, A. J., Collins, D. M., Keane, M., Coate, L., Kennedy, J., O'Reilly, S., Kelly, C., O'Connor, M., Martin, M., Murphy, C., Duffy, K., Walshe, J., Gullo, G., Mahgoub, T., Alvarez-Iglesias, A., Parker, I., Donachie, V., Teiserskiene, A., Madden, S. F., … Hennessy, B. T. (2025). TCHL - a phase II neo-adjuvant study assessing TCH (docetaxel, carboplatin and trastuzumab) and TCHL (docetaxel, carboplatin, trastuzumab and lapatinib) in HER-2 positive breast cancer patients: a 5-year follow-up with serum biomarker analysis. Acta oncologica (Stockholm, Sweden), 64, 751–760. https://doi.org/10.2340/1651-226X.2025.43143
  • Demeestere, I., Niman, S. M., Partridge, A. H., Diego, D. S., Kammler, R., Ruggeri, M., Colleoni, M., Shimizu, C., Saura, C., Gelmon, K. A., Saetersdal, A. B., Kroep, J. R., Mailliez, A., Amant, F., Ruız-Borrego, M., Lee, J. E., Kataoka, A., Walshe, J. M., Takei, J., Borstnar, S., … International Breast Cancer Study Group and the POSITIVE Trial Collaborators (2025). Corrigendum to "Hormonal factors predictive of fertility in patients with breast cancer interrupting adjuvant endocrine therapy to attempt pregnancy in POSITIVE trial" [The Breast 83 (2025) 104547]. Breast (Edinburgh, Scotland), 84, 104570. Advance online publication. https://doi.org/10.1016/j.breast.2025.104570
  • Duffy, M. J., Tang, M., & Crown, J. (2025). MYC as a Target for Cancer Treatment: from Undruggable to Druggable?. Targeted oncology, 20(5), 791–801. https://doi.org/10.1007/s11523-025-01169-x
  • Fasching, P. A., Stroyakovskiy, D., Yardley, D. A., Huang, C. S., Crown, J., Bardia, A., Chia, S., Im, S. A., Martin, M., Xu, B., Loi, S., Barrios, C., Untch, M., Moroose, R., Visco, F., Hortobagyi, G. N., Slamon, D. J., Fresco, R., Zarate, J. P., Li, Z., … Hurvitz, S. A. (2025). Ribociclib Plus Endocrine Therapy in Hormone Receptor-Positive/ERBB2-Negative Early Breast Cancer: 4-Year Outcomes From the NATALEE Randomized Clinical Trial. JAMA oncology, e253700. Advance online publication. https://doi.org/10.1001/jamaoncol.2025.3700
  • García-Saenz, J. A., Spera, G., Pollán, M., Bermejo, B., Ruiz-Borrego, M., Chan, A., Martín, M., Guerrero-Zotano, Á., Calvo, L., Rodríguez-Lescure, Á., Marín, M., Chap, L., Crown, J., Pienkowski, T., Bee, V., Casas, M., Polonio, Ó., Bezares, S., & Slamon, D. (2025). Body mass index as a predictive factor for efficacy of adjuvant taxane-based chemotherapy in early-stage breast cancer patients: A pooled analysis from adjuvant GEICAM Spanish Breast Cancer Group and TRIO Translational Research in Oncology Group studies. International journal of cancer, 157(4), 709–721. https://doi.org/10.1002/ijc.35432
  • Geyer, C. E., Jr, Untch, M., Huang, C. S., Mano, M. S., Mamounas, E. P., Wolmark, N., Rastogi, P., Schneeweiss, A., Redondo, A., Fischer, H. H., D'Hondt, V., Conlin, A. K., Guarneri, V., Wapnir, I. L., Jackisch, C., Arce-Salinas, C., Fasching, P. A., DiGiovanna, M. P., Crown, J. P., Wuelfing, P., … KATHERINE Study Group (2025). Survival with Trastuzumab Emtansine in Residual HER2-Positive Breast Cancer. The New England journal of medicine, 392(3), 249–257. https://doi.org/10.1056/NEJMoa2406070
  • Gillessen, S., Murphy, L., James, N. D., Sachdeva, A., El-Taji, O., Abdel-Aty, H., Adler, A. I., Amos, C., Attard, G., Varughese, M., Gale, J., Brown, S., Srihari, N., Birtle, A. J., Brown, M., Chan, K., Chowdhury, S., Cross, W., Dearnaley, D. P., Din, O., … STAMPEDE investigators (2025). Metformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol. The Lancet. Oncology, 26(8), 1018–1030. https://doi.org/10.1016/S1470-2045(25)00231-1
  • Gillessen, S., Tombal, B., Turco, F., Choudhury, A., Rodriguez-Vida, A., Gallardo, E., Velho, P. I., Nolè, F., Cruz, F., Loriot, Y., McDermott, R., Roumeguere, T., Daugaard, G., Yamamura, R., Bompas, E., Maroto, P., Polo, M. H., da Trindade, K. M., Preto, D. D., Skoneczna, I., … Saad, F. (2025). Decrease in Fracture Rate with Mandatory Bone-protecting Agents in the EORTC 1333/PEACE-3 Trial Comparing Radium-223 Combined with Enzalutamide Versus Enzalutamide Alone: A Safety Analysis. European urology, 87(3), 285–288. https://doi.org/10.1016/j.eururo.2024.11.027
  • Gillessen, S., Turco, F., Davis, I. D., Efstathiou, J. A., Fizazi, K., James, N. D., Shore, N., Small, E., Smith, M., Sweeney, C. J., Tombal, B., Zilli, T., Agarwal, N., Antonarakis, E. S., Aparicio, A., Armstrong, A. J., Bastos, D. A., Attard, G., Axcrona, K., Ayadi, M., … Omlin, A. (2025). Management of Patients with Advanced Prostate Cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC). European urology, 87(2), 157–216. https://doi.org/10.1016/j.eururo.2024.09.017
  • Goldman, J. W., Bueno, A. M., Dooms, C., Jhaveri, K., de Miguel, M., Piha-Paul, S. A., Unni, N., Zick, A., Mahipal, A., Suga, J. M., Naltet, C., Antoñanzas, M., Crown, J., Bebchuk, J., Eli, L. D., Lowenthal, B. H., & Mahalingam, D. (2025). Neratinib Efficacy in Patients With EGFR Exon 18-Mutant Non-Small-Cell Lung Cancer: Findings From the SUMMIT Basket Trial. Clinical lung cancer, 26(3), 191–200.e1. https://doi.org/10.1016/j.cllc.2024.12.003
  • Kelly, S. A., Ronan, K. E., Zameer, M., Brown, J., Johnston, G., Adams, R., Murphy, D., Kelly, D., Darwish, W., McCaffery, J., Coyne, G. O., Harrold, E., Iqbal, S., Cowzer, D., & Duffy, A. G. (2025). An analysis of compassionate access programmes for novel oncology drugs. Irish journal of medical science, 194(3), 807–815. https://doi.org/10.1007/s11845-025-03930-7
  • Keogan, A., Nguyen, T. N. Q., Bouzy, P., Stone, N., Jirstrom, K., Rahman, A., Gallagher, W. M., & Meade, A. D. (2025). Prediction of post-treatment recurrence in early-stage breast cancer using deep-learning with mid-infrared chemical histopathological imaging. NPJ precision oncology, 9(1), 18. https://doi.org/10.1038/s41698-024-00772-x
  • Khan, M. R., Kearney Sheehan, P., Bazin, A., Leonard, C., Corrigan, L., & McDermott, R. (2025). Impact of Testicular Cancer on the Socio-Economic Health, Sexual Health, and Fertility of Survivors-A Questionnaire Based Survey. Cancers, 17(11), 1826. https://doi.org/10.3390/cancers17111826
  • Khan, M., Sheehan, P. K., Bazin, A., Farooq, A. R., Leonard, C., Aleem, U., Corrigan, L., & McDermott, R. (2025). Long-term side effects of testicular cancer and treatment (observational study of mortality and morbidity in testicular cancer survivors). Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 33(5), 413. https://doi.org/10.1007/s00520-025-09447-0
  • Knox, J. J., Jang, G. H., Grant, R. C., Zhang, A., Ma, L., Elimova, E., Jang, R., Moore, M., Biagi, J., Tehfe, M., Ramjeesingh, R., Tsang, E. S., Holter, S., Ramotar, S., Hutchinson, S., Liang, S. B., Lungu, I. M., Moura, S., Wang, Y., Perera, S., … O'Kane, G. M. (2025). Whole genome and transcriptome profiling in advanced pancreatic cancer patients on the COMPASS trial. Nature communications, 16(1), 5919. https://doi.org/10.1038/s41467-025-60808-z
  • Krzyzanowska, A., Higgins, D. F., Barron, S., Loughman, T., O'Neill, A., Sheehan, K. M., Wang, C. A., Fender, B., McGuire, L., Fay, J., O'Grady, A., O'Leary, D., Watson, R. W., Bjartell, A., & Gallagher, W. M. (2024). Clinical validation of a biopsy-based six-gene signature prognostic for aggressive prostate cancer. BJUI compass, 6(1), e474. https://doi.org/10.1002/bco2.474
  • Leone, G., Orlando, F., Dutey-Magni, P., Vainauskas, O., Grist, E., Ciani, Y., Lall, S., Thakali, S., Wingate, A., Wetterskog, D., Sachdeva, A., Sydes, M. R., McPhail, N., Sreenivasan, T., O'Sullivan, J. M., Clarke, N. W., Parmar, M. K. B., Brown, L. C., James, N. D., Demichelis, F., … STAMPEDE collaborators (2025). Plasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer: the STAMPEDE Phase 3 Randomized Clinical Trial. JAMA oncology, 11(4), 426–429. Advance online publication. https://doi.org/10.1001/jamaoncol.2024.7051
  • Li, M., Devane, D., Beecher, C., Dowling, M., Duffy, A. G., Duggan, C., Grimes, D. R., Kennan, A., Kilty, C., Nsangi, A., Oxman, A. D., Stewart, D. C., Toomey, E., & Tierney, M. (2025). Developing critical thinking and decision-making skills for cancer information: the Informed Health Choice-Cancer online learning resource. Journal of cancer survivorship : research and practice, 10.1007/s11764-025-01874-6. Advance online publication. https://doi.org/10.1007/s11764-025-01874-6
  • Li, Z., Aliseda, D., Jones, O., Rajendran, L., Magyar, C., Grant, R., O'Kane, G. M., Saborowski, A., Sapisochin, G., & Vogel, A. (2024). Recent advances in systemic therapy for advanced biliary tract cancer: A systematic review and meta-analysis using reconstructed RCT survival data. JHEP reports : innovation in hepatology, 7(3), 101290. https://doi.org/10.1016/j.jhepr.2024.101290
  • Li, Z., Chen, I. C., Centonze, L., Magyar, C. T. J., Choi, W. J., Ivanics, T., O'Kane, G. M., Vogel, A., Erdman, L., De Carlis, L., Lerut, J., Lai, Q., Agopian, V. G., Mehta, N., Chen, C. L., & Sapisochin, G. (2025). Validation of the Toronto recurrence inference using machine-learning for post-transplant hepatocellular carcinoma model. Communications medicine, 5(1), 284. https://doi.org/10.1038/s43856-025-00994-5
  • Li, Z., Chen, I. C., Centonze, L., Magyar, C. T. J., Choi, W. J., Shah, S., O'Kane, G. M., Vogel, A., De Carlis, L., Lerut, J., Lai, Q., Mehta, N., Chen, C. L., & Sapisochin, G. (2025). Analysis of treatment benefits and prognostic factors for posttransplant HCC recurrence in a large Euro-American-Asian cohort. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 31(4), 450–463. https://doi.org/10.1097/LVT.0000000000000501
  • Li, Z., Yan, M., Claasen, M. P. A. W., Rajendran, L., Magyar, C. T. J., Saha, S., Lee, C., Selzner, N., Jaeckel, E., Ghanekar, A., Cattral, M., Sayed, B. A., Selzner, M., McGilvray, I., Shwaartz, C., Reichman, T., O'Kane, G. M., Vogel, A., Grant, R. C., Kim, T. K., … Sapisochin, G. (2025). SBRT for bridging and downstaging HCC before transplant. JHEP reports : innovation in hepatology, 7(8), 101451. https://doi.org/10.1016/j.jhepr.2025.101451
  • Magyar, C. T. J., O'Kane, G. M., Aceituno, L., Li, Z., Vogel, A., Bruix, J., Mazzaferro, V., & Sapisochin, G. (2025). Liver Transplantation for Hepatocellular Carcinoma: An Expanding Cornerstone of Care in the Era of Immunotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 43(5), 589–604. https://doi.org/10.1200/JCO.24.00857
  • Magyar, C. T. J., Perera, S., Rajendran, L., Li, Z., Almugbel, F. A., Feng, S., Choi, W. J., Aceituno, L., Vogel, A., Grant, R. C., Selzner, N., Jaeckel, E., Falla-Rad, N., Knox, J. J., Chen, E. X., Sapisochin, G., & O'Kane, G. M. (2025). Comparative Outcome Analysis of Lenvatinib Versus Sorafenib for Recurrence of Hepatocellular Carcinoma After Liver Transplantation. Transplantation, 109(4), 681–690. https://doi.org/10.1097/TP.0000000000005240
  • Magyar, C. T. J., Rajendran, L., Li, Z., Banz, V., Vogel, A., O'Kane, G. M., Chan, A. C., & Sapisochin, G. (2025). Precision surgery for hepatocellular carcinoma. The lancet. Gastroenterology & hepatology, 10(4), 350–368. https://doi.org/10.1016/S2468-1253(24)00434-5
  • Maharaj, T., Steele, C., Gyorffy, H., Nicholson, S., Milewski, L., Aird, J. J., Mulsow, J., & Cowzer, D. (2025). Young-onset epithelioid type malignant peritoneal mesothelioma with loss of BAP1 gene expression. BMJ case reports, 18(7), e264825. https://doi.org/10.1136/bcr-2025-264825
  • Mahdi, A. F., Ashfield, N., Crown, J., & Collins, D. M. (2025). Pre-Clinical Rationale for Amcenestrant Combinations in HER2+/ER+ Breast Cancer. International journal of molecular sciences, 26(2), 460. https://doi.org/10.3390/ijms26020460
  • Mehra, N., Antonarakis, E. S., Park, S. H., Goh, J. C., McDermott, R., Sala Gonzalez, N., Fong, P. C., Greil, R., De Santis, M., Yanez, P. E., Huang, Y. H., Begbie, S. D., Rey, F., Kramer, G., Suzuki, H., Saretsky, T. L., Ghate, S. R., Cui, Y., Hosius, C., & Yu, E. Y. (2025). Patient-reported Outcomes in KEYLYNK-010: Pembrolizumab Plus Olaparib Versus Abiraterone or Enzalutamide for Participants with Biomarker-unselected, Previously Treated Metastatic Castration-resistant Prostate Cancer. European urology oncology, 8(4), 1030–1040. https://doi.org/10.1016/j.euo.2025.04.018
  • Myojin, Y., Babaei, S., Trehan, R., Hoffman, C., Kedei, N., Ruf, B., Benmebarek, M. R., Bauer, K. C., Huang, P., Ma, C., Monge, C., Xie, C., Hrones, D., Duffy, A. G., Armstrong, P., Kocheise, L., Desmond, F., Buchalter, J., Galligan, M., Cantwell, C., … Greten, T. F. (2025). Multiomics analysis of immune correlatives in hepatocellular carcinoma patients treated with tremelimumab plus durvalumab. Gut, 74(6), 983–995. https://doi.org/10.1136/gutjnl-2024-334026
  • O'Grady, S., Ralston, J. C., McKiernan, E., Drummond, F. J., Rynne, J., Mitchell, D., Bray, I., Gallagher, W. M., Drury, A., & Kolch, W. (2025). Research opportunities in precision oncology: perspectives on biospecimen and genomic data sharing from adults with cancer in Ireland. Irish journal of medical science, 10.1007/s11845-025-04082-4. Advance online publication. https://doi.org/10.1007/s11845-025-04082-4
  • O'Grady, S., Ralston, J. C., McKiernan, E., Lanigan, F., Salauddin, M., Sharmin, S., McVeigh, T., Gallagher, W. M., Guerin, S., Rahman, A., & Kolch, W. (2025). Invisible spectrum: a model for minority community public engagement in cancer research. Research involvement and engagement, 11(1), 53. https://doi.org/10.1186/s40900-025-00726-y
  • Peccatori, F. A., Niman, S. M., Partridge, A. H., Ruggeri, M., Colleoni, M., Saura, C., Shimizu, C., Satersdal, A. B., Kroep, J. R., Gelmon, K., Amant, F., Mailliez, A., Moore, H. C. F., Ruiz-Borrego, M., Walshe, J. M., Borges, V. F., Gombos, A., Kataoka, A., Rousset-Jablonski, C., Borstnar, S., … International Breast Cancer Study Group and the POSITIVE Trial Collaborators (2025). Breastfeeding After Hormone Receptor-Positive Breast Cancer: Results From the POSITIVE Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 43(24), 2712–2719. https://doi.org/10.1200/JCO-24-02697
  • Petrylak, D. P., Ratta, R., Matsubara, N., Korbenfeld, E., Gafanov, R., Mourey, L., Todenhöfer, T., Gurney, H., Kramer, G., Bergman, A. M., Zalewski, P., De Santis, M., Armstrong, A. J., Gerritsen, W., Pachynski, R., Byun, S. S., Retz, M., Levesque, E., McDermott, R., Bracarda, S., … Fizazi, K. (2025). Pembrolizumab Plus Docetaxel Versus Docetaxel for Previously Treated Metastatic Castration-Resistant Prostate Cancer: The Randomized, Double-Blind, Phase III KEYNOTE-921 Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 43(14), 1638–1649. https://doi.org/10.1200/JCO-24-01283
  • Rimassa, L., Lamarca, A., O'Kane, G. M., Edeline, J., McNamara, M. G., Vogel, A., Fassan, M., Forner, A., Kendall, T., Adeva, J., Casadei-Gardini, A., Fornaro, L., Hollebecque, A., Lowery, M. A., Macarulla, T., Malka, D., Mariamidze, E., Niger, M., Ustav, A., Bridgewater, J., … Braconi, C. (2025). Correction to "New systemic treatment paradigms in advanced biliary tract cancer and variations in patient access across Europe" [The Lancet Regional Health - Europe, volume 50, March 2025, 101170]. The Lancet regional health. Europe, 53, 101306. https://doi.org/10.1016/j.lanepe.2025.101306
  • Rischin, D., Porceddu, S., Day, F., Brungs, D. P., Christie, H., Jackson, J. E., Stein, B. N., Su, Y. B., Ladwa, R., Adams, G., Bowyer, S. E., Otty, Z., Yamazaki, N., Bossi, P., Challapalli, A., Hauschild, A., Lim, A. M., Patel, V. A., Walker, J. L., De Liz Vassen Schurmann, M., … C-POST Trial Investigators (2025). Adjuvant Cemiplimab or Placebo in High-Risk Cutaneous Squamous-Cell Carcinoma. The New England journal of medicine, 393(8), 774–785. https://doi.org/10.1056/NEJMoa2502449
  • Tang, M., Crown, J., & Duffy, M. J. (2025). Targeting MYC for the treatment of breast cancer: use of the novel MYC-GSPT1 degrader, GT19630. Investigational new drugs, 43(1), 167–179. https://doi.org/10.1007/s10637-024-01504-5
  • Van den Hurk, K., Lommen, K., Coussement, L., van den Kerkhof, D., Beckers, M., Trooskens, G., Van Neste, L., Oosterhof, M., van Doorn, R., van den Oord, J. J., Kerkhofs, T., Aarts, M. J. B., Ramaekers, B., Joore, M., Winnepenninckx, V. J. L., Van Criekinge, W., Gallagher, W., De Meyer, T., Smits, K. M., & van Engeland, M. (2025). Comprehensive Analysis of the Melanoma DNA Methylome Identifies LY75 Methylation as an Independent Marker Predicting Poor Clinical Outcome. The Journal of investigative dermatology, S0022-202X(25)02311-5. Advance online publication. https://doi.org/10.1016/j.jid.2025.07.010
  • Victory, L., Quigley, C., Doheny, J., Flynn, A., Potter, S., & Moloney, F. J. (2025). Goldfinger: a case of a patient with metal tattooing mimicking recurrent melanoma. Clinical and experimental dermatology, 50(2), 491–493. https://doi.org/10.1093/ced/llae370

Our 2024 list of publications include articles produced by our cluster's researchers as well as publications arising from the hard work of our trial units at St Vincent's University Hospital and The Mater Misericordiae University Hospital.

  • AlSendi, M., Flynn, C. R., Khan, M. R., Selvadurai, P., Crown, J., McDermott, R. S., Walshe, J. M., Fennelly, D. W., Hanrahan, E. O., Doherty, M., & Higgins, M. J. (2024). Pilot study of the implementation of G8 screening tool, Cognitive screening assessment and Chemotherapy Toxicity assessment in older adults with cancer in a Tertiary University Hospital in Ireland. Irish journal of medical science, 193(1), 45–50. https://doi.org/10.1007/s11845-023-03446-y
  • Azam, H., Veale, C., Zitzmann, K., Marcone, S., Gallagher, W. M., & Prencipe, M. (2024). Identification of druggable targets from the interactome of the Androgen Receptor and Serum Response Factor pathways in prostate cancer. PloS one, 19(12), e0309491. https://doi.org/10.1371/journal.pone.0309491
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  • McSorley, L. M., Tharmabala, M., Al Rahbi, F., Keane, F., Evoy, D., Geraghty, J. G., Rothwell, J., McCartan, D. P., Greally, M., O'Connor, M., O'Mahony, D., Keane, M., Kennedy, M. J., O'Reilly, S., Millen, S. J., Crown, J. P., Kelly, C. M., Prichard, R. S., Quinn, C. M., & Walshe, J. M. (2024). Real-World Analysis of the Clinical and Economic Impact of the 21-Gene Recurrence Score (RS) in Invasive Lobular Early-Stage Breast Carcinoma in Ireland. Current oncology (Toronto, Ont.), 31(3), 1302–1310. https://doi.org/10.3390/curroncol31030098
  • Miceli, R., Eriksson, H., Lo Russo, G., Alfieri, S., Moksnes Bjaanæs, M., Pietrantonio, F., De Cecco, L., Prelaj, A., Proto, C., Franzén, J., McDonnell, D., Berenguer Pina, J. J., Beninato, T., Mazzeo, L., Giannatempo, P., Verzoni, E., Crown, J., Helland, Å., & Eustace, A. (2024). Gender Difference in sidE eFfects of ImmuNotherapy: a possible clue to optimize cancEr tReatment (G-DEFINER): study protocol of an observational prospective multicenter study. Acta oncologica (Stockholm, Sweden), 63, 213–219. https://doi.org/10.2340/1651-226X.2024.24179
  • Moser, J. C., Bhatia, S., Amin, A., Pavlick, A. C., Betts, K. A., Du, E. X., Poretta, T., Shelley, K., Srinivasan, S., Sakkal, L. A., Palaia, J., Lobo, M., Pe Benito, M., Linton, J. A., Chen, Y., Xu, C., Yin, L., Sundar, M., & Weber, J. (2024). Clinical outcomes of adjuvant nivolumab in resected stage III melanoma: comparison of CheckMate 238 trial and real-world data. Cancer immunology, immunotherapy : CII, 73(7), 116. https://doi.org/10.1007/s00262-024-03697-3
  • O'Kane, G., Tabrizian, P., Aceituno, L., Kulik, L., & Sapisochin, G. (2024). Integrating immune check inhibitors in liver transplantation for hepatocellular carcinoma: The right time and the right patient. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 24(10), 1719–1721. https://doi.org/10.1016/j.ajt.2024.06.006
  • O'Reilly, M., Krstic, A., Iglesias-Martinez, L. F., Ryan, É. J., Moran, B., Winter, D., Sheahan, K., McDermott, R., & Kolch, W. (2024). Genomic and Transcriptomic Analysis of a Patient with Early-Onset Colorectal Cancer and Therapy-Induced Focal Nodular Hyperplasia: A Case Report. Journal of personalized medicine, 14(6), 639. https://doi.org/10.3390/jpm14060639
  • Powell, S., Kulakova, K., Hanratty, K., Khan, R., Casserly, P., Crown, J., Walsh, N., & Kennedy, S. (2024). Molecular Analysis of Salivary and Lacrimal Adenoid Cystic Carcinoma. Cancers, 16(16), 2868. https://doi.org/10.3390/cancers16162868
  • Quirke, N. P., Cullinane, C., Turk, M. A., Shafique, N., Evoy, D., Geraghty, J., McCartan, D., Quinn, C., Walshe, J. M., McDermott, E., Rutherford, C., & Prichard, R. S. (2024). Invasive lobular carcinoma of the breast; clinicopathologic profile and response to neoadjuvant chemotherapy over a 15-year period. Breast (Edinburgh, Scotland), 76, 103739. https://doi.org/10.1016/j.breast.2024.103739
  • Rajaram, S., Synnott, N. C., Crown, J., Madden, S. F., & Duffy, M. J. (2024). Targeting mutant p53 with arsenic trioxide: A preclinical study focusing on triple negative breast cancer. Translational oncology, 46, 102025. https://doi.org/10.1016/j.tranon.2024.102025
  • Rastogi, P., Bandos, H., Lucas, P. C., van 't Veer, L. J., Wei, J. J., Geyer, C. E., Jr, Fehrenbacher, L., Chia, S. K. L., Brufsky, A. M., Walshe, J. M., Soori, G. S., Dakhil, S. R., Paik, S., Swain, S. M., Menicucci, A. R., Audeh, M. W., Wolmark, N., & Mamounas, E. P. (2024). Utility of the 70-Gene MammaPrint Assay for Prediction of Benefit From Extended Letrozole Therapy in the NRG Oncology/NSABP B-42 Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 42(30), 3561–3569. https://doi.org/10.1200/JCO.23.01995
  • Robledo, K. P., Lefresne, S., Soon, Y. Y., Sahgal, A., Pinkham, M. B., Nichol, A., Soo, R. A., Parmar, A., Hegi-Johnson, F., Doherty, M., Solomon, B. J., Shultz, D. B., Tham, I. W., Sacher, A. G., Tey, J., Leong, C. N., Koh, W. Y., Huang, Y., Ang, Y. L. E., Low, J., … Ho, C. (2024). Protocol for a systematic review with prospective individual patient data meta-analysis in EGFR-mutant NSCLC with brain metastases to assess the effect of SRS+osimertinib compared to osimertinib alone: the STARLET Collaboration. BMJ open, 14(7), e078335. https://doi.org/10.1136/bmjopen-2023-078335
  • Ronan, K., Jordan, E., Leonard, C., & McDermott, R. (2024). Frequency of next-generation sequencing, prevalence of targetable mutations and response to targeted therapies amongst patients with metastatic urothelial cancer in Ireland: a multi-centre retrospective study of real-world data. Irish journal of medical science, 193(3), 1155–1161. https://doi.org/10.1007/s11845-023-03569-2
  • Shore, N., Carles, J., McDermott, R., Agarwal, N., & Tombal, B. (2024). Treatment intensification with radium-223 plus enzalutamide in patients with metastatic castration-resistant prostate cancer. Frontiers in medicine, 11, 1460212. https://doi.org/10.3389/fmed.2024.1460212
  • Slamon, D. J., Diéras, V., Rugo, H. S., Harbeck, N., Im, S. A., Gelmon, K. A., Lipatov, O. N., Walshe, J. M., Martin, M., Chavez-MacGregor, M., Bananis, E., Gauthier, E., Lu, D. R., Kim, S., & Finn, R. S. (2024). Overall Survival With Palbociclib Plus Letrozole in Advanced Breast Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 42(9), 994–1000. https://doi.org/10.1200/JCO.23.00137
  • Slamon, D., Lipatov, O., Nowecki, Z., McAndrew, N., Kukielka-Budny, B., Stroyakovskiy, D., Yardley, D. A., Huang, C. S., Fasching, P. A., Crown, J., Bardia, A., Chia, S., Im, S. A., Ruiz-Borrego, M., Loi, S., Xu, B., Hurvitz, S., Barrios, C., Untch, M., Moroose, R., … Hortobagyi, G. (2024). Ribociclib plus Endocrine Therapy in Early Breast Cancer. The New England journal of medicine, 390(12), 1080–1091. https://doi.org/10.1056/NEJMoa2305488
  • Treacy, T., O'Meara, Y., Galligan, M. C., Henry, A. L., Lensen, S. F., Higgins, M. J., Hickey, M., & Brennan, D. J. (2024). The Sleepio After Cancer (SAC) study. Digital cognitive behavioural therapy for insomnia (dCBT-I) in women cancer patients - Trial protocol of a randomised controlled trial. Contemporary clinical trials, 136, 107337. https://doi.org/10.1016/j.cct.2023.107337
  • Tuzova AV, Moran B, Russell NM, et al. Deciphering epigenetic regulation of enhancers in high-risk prostate cancer. Genes Chromosomes Cancer. 2024; 63(2):e23218. doi:10.1002/gcc.23218
  • Venken, T., Miller, I. S., Arijs, I., Thomas, V., Barat, A., Betge, J., Zhan, T., Gaiser, T., Ebert, M. P., O'Farrell, A. C., Prehn, J., Klinger, R., O'Connor, D. P., Moulton, B., Murphy, V., Serna, G., Nuciforo, P. G., McDermott, R., Bird, B., Leonard, G., … Byrne, A. T. (2024). Analysis of cell free DNA to predict outcome to bevacizumab therapy in colorectal cancer patients. NPJ genomic medicine, 9(1), 33. https://doi.org/10.1038/s41525-024-00415-x
  • Walsh, M., Jordan, A., Schäfer, L., Joha, J., Heapes, B., Noonan, M., Gallagher, W., Gallagher, H., Manecksha, R. P., Galvin, D., Nason, G., Martin, T., Lyons, C., O'Connor, R., UCD Prostate Patient Advisory Committee, Drummond, F. J., Kilty, C., & Perry, A. S. (2024). IMPROVER (Involving Men with Prostate Cancer in Engaged Research): Assessing Patient Experience With Testing, Diagnosis, And Surveillance. Clinical genitourinary cancer, 22(3), 102063. https://doi.org/10.1016/j.clgc.2024.102063
  • Weiss, L., Uhrig, W., Kelliher, S., Szklanna, P. B., Prendiville, T., Comer, S. P., Edebiri, O., Egan, K., Lennon, Á., Kevane, B., Murphy, S., Ní Áinle, F., & Maguire, P. B. (2024). Proteomic analysis of extracellular vesicle cargoes mirror the cardioprotective effects of rivaroxaban in patients with venous thromboembolism. Proteomics. Clinical applications, 18(4), e202300014. https://doi.org/10.1002/prca.202300014
  • Zhihao Li, Christian T.J. Magyar, Grainne M. O'Kane, Gonzalo Sapisochin, Chapter 25 - Challenges of liver transplantation for transplant oncology indications, Editor(s): Maen A. Abdelrahim, Transplant Oncology, Academic Press, 2025, Pages 295-311, ISBN 9780443219016, https://doi.org/10.1016/B978-0-443-21901-6.00025-2.

Our 2023 list of publications include articles produced by our cluster's researchers as well as publications arising from the hard work of our trial units at St Vincent's University Hospital and The Mater Misericordiae University Hospital.

  • Westphalen, C. B., Federer-Gsponer, J., Pauli, C., Karapetyan, A. R., Chalabi, N., Durán-Pacheco, G., ... & Krämer, A. (2023). Baseline mutational profiles of patients with carcinoma of unknown primary origin enrolled in the CUPISCO study. ESMO open, 8(6), 102035.
  • Vergote, I., Van Nieuwenhuysen, E., O'Cearbhaill, R. E., Westermann, A., Lorusso, D., Ghamande, S., ... & Monk, B. J. (2023). Tisotumab vedotin in combination with carboplatin, pembrolizumab, or bevacizumab in recurrent or metastatic cervical cancer: results from the innovaTV 205/GOG-3024/ENGOT-cx8 study. Journal of clinical oncology, 41(36), 5536.
  • Jhaveri, K., O’Shaughnessy, J., Fasching, P. A., Tolaney, S. M., Yardley, D. A., Sharma, V. K., ... & Rugo, H. S. (2023). Matching-adjusted indirect comparison of PFS and OS comparing ribociclib plus letrozole versus palbociclib plus letrozole as first-line treatment of HR+/HER2− advanced breast cancer. Therapeutic Advances in Medical Oncology, 15, 17588359231216095.
  • Dalli, J., Epperlein, J. P., Jindal, A., Potter, S., & Cahill, R. A. (2023). A Case Report Demonstrating Quantitative Indocyanine Green Fluorescence Angiography for Single-Versus Dual-vein Microvascular Anastomosis. Plastic and Reconstructive Surgery–Global Open, (12), e5468.
  • Lynch, E., Duffy, A. G., & Kelly, R. J. (2023). Role of Immunotherapy in Gastroesophageal Cancers—Advances, Challenges and Future Strategies. Cancers, 15(22), 5401.
  • Kim, H. R., Awad, M. M., Navarro, A., Gottfried, M., Peters, S., Csőszi, T., ... & Rudin, C. M. (2023). Patient-Reported Health-Related Quality of Life in KEYNOTE-604: Pembrolizumab or Placebo Added to Etoposide and Platinum as First-Line Therapy for Extensive-Stage Small Cell Lung Cancer. JTO Clinical and Research Reports, 4(11), 100572.
  • Ronan, K., Jordan, E., Leonard, C., & McDermott, R. (2023). Frequency of next-generation sequencing, prevalence of targetable mutations and response to targeted therapies amongst patients with metastatic urothelial cancer in Ireland: a multi-centre retrospective study of real-world data. Irish Journal of Medical Science (1971-), 1-7.
  • Duffy, M. J., & Crown, J. (2023). Circulating tumor DNA (ctDNA): can it be used as a pan-cancer early detection test?. Critical Reviews in Clinical Laboratory Sciences, 1-13.
  • McMahon, M. E., O'Brien, L., Heary, T., Potter, S., & O'Sullivan, B. (2023). Management of the intraoperative loss of microsurgical needles: A literature review and clinical survey. The Surgeon. 
  • Murtagh, G., Januzzi, J. L., Scherrer‐Crosbie, M., Neilan, T. G., Dent, S., Ho, J. E., ... & Akhter, N. (2023). Circulating Cardiovascular Biomarkers in Cancer Therapeutics‐Related Cardiotoxicity: Review of Critical Challenges, Solutions, and Future Directions. Journal of the American Heart Association, 12(21), e029574.
  • Cosgrove, N., Eustace, A. J., O’Donovan, P., Madden, S. F., Moran, B., Crown, J., ... & Furney, S. J. (2023). Predictive modelling of response to neoadjuvant therapy in HER2+ breast cancer. NPJ Breast Cancer, 9(1), 72.
  • Kummar, S., Shen, L., Hong, D. S., McDermott, R., Keedy, V. L., Casanova, M., ... & Tan, D. S. (2023). Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas. Cancer, 129(23), 3772-3782.
  • O’Reilly, M., & Higgins, M. (2023). Evolving role of liquid biopsies in management of breast cancer. Hospital Professional News. https://hospitalprofessionalnews.ie/2023/02/14/evolving-role-of-liquid-biopsies-in-management-of-breast-cancer/
  • Reynolds, J. V., Preston, S. R., O'Neill, B., Lowery, M. A., Baeksgaard, L., Crosby, T., ... & O'Sullivan, J. (2023). Trimodality therapy versus perioperative chemotherapy in the management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction (Neo-AEGIS): an open-label, randomised, phase 3 trial. The Lancet Gastroenterology & Hepatology.
  • O’Reilly, E., Khalifa, K., Cosgrave, J., Azam, H., Prencipe, M., Simpson, J. C., ... & Perry, A. S. (2023). Cannabidiol Inhibits the Proliferation and Invasiveness of Prostate Cancer Cells. Journal of Natural Products.
  • Fong, C. H., Meti, N., Kruser, T., Weiss, J., Liu, Z. A., Takami, H., ... & Shultz, D. B. (2023). Recommended first-line management of asymptomatic brain metastases from EGFR mutant and ALK positive non-small cell lung cancer varies significantly according to specialty: an international survey of clinical practice. Journal of Thoracic Disease, 15(8), 4367.
  • Lynch, E., Duffy, A. G., & Kelly, R. J. (2023). Brave new world-new and emerging treatments for gastric cancer. Chinese Clinical Oncology, cco-23.
  • Kieran, R., Mitchell, T., Fazari, A. A., Chinoy, A., Moloney, C., & McCaffrey, J. (2023). DPD deficiency in an Irish oncology centre: Prevalence and clinical implications. Journal of Oncology Pharmacy Practice, 10781552231192107.
  • Thagaard, J., Broeckx, G., Page, D. B., Jahangir, C. A., Verbandt, S., Kos, Z., ... & Salgado, R. (2023). Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: a report of the international immuno-oncology biomarker working group. The Journal of Pathology.
  • Page, D. B., Broeckx, G., Jahangir, C. A., Verbandt, S., Gupta, R. R., Thagaard, J., ... & Bouchmaa, N. (2023). Spatial analyses of immune cell infiltration in cancer: current methods and future directions. A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer. The Journal of Pathology.
  • Beauchamp, K., Moran, B., O’Brien, T., Brennan, D., Crown, J., Sheahan, K., & Cotter, M. B. (2023). Carcinoma of unknown primary (CUP): an update for histopathologists. Cancer and Metastasis Reviews, 1-12.
  • Azam, H., Maher, S., Clarke, S., Gallagher, W. M., & Prencipe, M. (2023). SRF inhibitors reduce prostate cancer cell proliferation through cell cycle arrest in an isogenic model of castrate-resistant prostate cancer. Cell Cycle, 1-18.
  • Donnelly, M., Ryan, O. K., Ryan, É. J., Creavin, B., O’Reilly, M., McDermott, R., ... & Winter, D. C. (2023). Total neoadjuvant therapy versus standard neoadjuvant treatment strategies for the management of locally advanced rectal cancer: network meta-analysis of randomized clinical trials. British Journal of Surgery, znad177.
  • Carolan, D., Milling, R., Quinlan, C., Carr, S., Kinsella, A., McDermott, B. R., ... & Potter, S. (2023). Are Plastic Surgery Trainees Accurate Assessors of Their Own Microsurgical Skill?. JPRAS open.
    Flynn, C. R., Kumar, A. P., O'Shea, D., & Higgins, M. J. (2023). Alpelisib-induced thyroiditis in a patient with metastatic breast cancer: Is routine monitoring of thyroid function required?. Current Problems in Cancer: Case Reports, 9, 100219.
  • Silva, R., Glennon, K., Metoudi, M., Moran, B., Salta, S., Slattery, K., ... & Brennan, D. J. (2023). Unveiling the epigenomic mechanisms of acquired platinum‐resistance in high‐grade serous ovarian cancer. International Journal of Cancer, 153(1), 120-132.
  • Tang, M., Crown, J., & Duffy, M. J. (2023). Degradation of MYC by the mutant p53 reactivator drug, COTI-2 in breast cancer cells. Investigational New Drugs, 1-10.
  • Slamon, D. J., Fasching, P. A., Hurvitz, S., Chia, S., Crown, J., Martín, M., ... & Hortobagyi, G. N. (2023). Rationale and trial design of NATALEE: a Phase III trial of adjuvant ribociclib+ endocrine therapy versus endocrine therapy alone in patients with HR+/HER2− early breast cancer. Therapeutic Advances in Medical Oncology, 15, 17588359231178125.
  • Myers, C., Bennett, K., Kelly, C., Walshe, J., O’Sullivan, N., Quinn, M., ... & Cahir, C. (2023). Impact of COVID-19 on health care and quality of life in women with breast cancer. JNCI Cancer Spectrum, 7(3), pkad033.
  • Mamounas, E. P., Bandos, H., Rastogi, P., Lembersky, B. C., Jeong, J. H., Geyer Jr, C. E., ... & Wolmark, N. (2023). Ten-year Update: NRG Oncology/NSABP B-42 Randomized Trial: Extended Letrozole Therapy in Early-stage Breast Cancer. JNCI: Journal of the National Cancer Institute, djad078.
  • Antonarakis, E. S., Park, S. H., Goh, J. C., Shin, S. J., Lee, J. L., Mehra, N., McDermott, R., Sala-Gonzalez, N., Fong, P. C., Greil, R., Retz, M., Sade, J. P., Yanez, P., Huang, Y. H., Begbie, S. D., Gafanov, R. A., De Santis, M., Rosenbaum, E., Kolinsky, M. P., Rey, F., … Yu, E. Y. (2023). Pembrolizumab Plus Olaparib for Patients With Previously Treated and Biomarker-Unselected Metastatic Castration-Resistant Prostate Cancer: The Randomized, Open-Label, Phase III KEYLYNK-010 Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, JCO2300233. Advance online publication. https://doi.org/10.1200/JCO.23.00233
  • Partridge, A. H., Niman, S. M., Ruggeri, M., Peccatori, F. A., Azim Jr, H. A., Colleoni, M., ... & Pagani, O. (2023). Interrupting endocrine therapy to attempt pregnancy after breast cancer. New England Journal of Medicine, 388(18), 1645-1656.
  • Abida, W., Campbell, D., Patnaik, A., Bryce, A. H., Shapiro, J., Bambury, R. M., ... & Chowdhury, S. (2023). Rucaparib for the Treatment of Metastatic Castration-resistant Prostate Cancer Associated with a DNA Damage Repair Gene Alteration: Final Results from the Phase 2 TRITON2 Study. European Urology.
  • Sheill, G., Brady, L., Hayes, B., Baird, A. M., Guinan, E., Vishwakarma, R., ... & Finn, S. (2023). ExPeCT: a randomised trial examining the impact of exercise on quality of life in men with metastatic prostate cancer. Supportive Care in Cancer, 31(5), 292.
  • Early Breast Cancer Trialists’ Collaborative Group. (2023). Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials. The Lancet, 401(10384), 1277-1292.
  • Denkert, C., Lambertini, C., Fasching, P. A., Pogue-Geile, K. L., Mano, M. S., Untch, M., ... & Basik, M. (2023). Biomarker Data from the Phase III KATHERINE Study of Adjuvant T-DM1 versus Trastuzumab for Residual Invasive Disease after Neoadjuvant Therapy for HER2-Positive Breast Cancer. Clinical Cancer Research, 29(8), 1569-1581.
  • Harvey, H., Carroll, H., Murphy, V., Ballot, J., O'Grady, M., O'Hare, D., ... & O'Reilly, S. (2023). The Impact of a National Cyberattack Affecting Clinical Trials: The Cancer Trials Ireland Experience. JCO Clinical Cancer Informatics, 7, e2200149.
  • Facon, T., Kumar, S., Plesner, T., Orlowski, R. Z., Moreau, P., Bahlis, N., ... & Usmani, S. Z. (2019). Daratumumab plus lenalidomide and dexamethasone for untreated myeloma. New England Journal of Medicine, 380(22), 2104-2115.
  • Roche, S., Gaule, P., Winrow, D., Mukherjee, N., O’Neill, F., Conlon, N. T., ... & Eustace, A. J. (2023). Preclinical evaluation of Insulin-like growth factor receptor 1 (IGF1R) and Insulin Receptor (IR) as a therapeutic targets in triple negative breast cancer. Plos one, 18(3), e0282512.
  • Fizazi, K., Piulats, J. M., Reaume, M. N., Ostler, P., McDermott, R., Gingerich, J. R., ... & Bryce, A. H. (2023). Rucaparib or physician’s choice in metastatic prostate cancer. New England Journal of Medicine, 388(8), 719-732.
  • de Azambuja, E., Agostinetto, E., Procter, M., Eiger, D., Pondé, N., Guillaume, S., ... & Committee, A. S. (2023). Cardiac safety of dual anti-HER2 blockade with pertuzumab plus trastuzumab in early HER2-positivebreast cancer in the APHINITY trial. ESMO Open, 8(1), 100772.
  • Monge, C., Xie, C., Myojin, Y., Coffman, K., Hrones, D. M., Wang, S., ... & Greten, T. F. (2023). Phase I/II study of PexaVec in combination with immune checkpoint inhibition in refractory metastatic colorectal cancer. Journal for Immunotherapy of Cancer, 11(2).
  • O’Neill, F., Allen-Coyle, T. J., Roche, S., Meiller, J., Conlon, N. T., Swan, N., ... & Clynes, M. (2023). Alteration in Levels of Specific miRNAs and Their Potential Protein Targets between Human Pancreatic Cancer Samples, Adjacent Normal Tissue, and Xenografts Derived from These Tumors. Life, 13(3), 608.
  • O’Reilly, M., Linehan, A., Krstic, A., Kolch, W., Sheahan, K., Winter, D. C., & Mc Dermott, R. (2023). Oncotherapeutic Strategies in Early Onset Colorectal Cancer. Cancers, 15(2), 552.
  • Lynch, E., Duffy, A. G., & Kelly, R. J. (2023). Immune Checkpoint Inhibitors: Changing the Treatment Landscape in Esophagogastric Adenocarcinoma. Pharmaceuticals, 16(1), 102. 

Our 2022 list of publications include articles produced by our cluster's researchers as well as publications arising from the hard work of our trial units at St Vincent's University Hospital and The Mater Misericordiae University Hospital.

  • Gnant, M., Dueck, A. C., Frantal, S., Martin, M., Burstein, H. J., Greil, R., ... & Mayer, E. L. (2022). Adjuvant palbociclib for early breast cancer: the PALLAS trial results (ABCSG-42/AFT-05/BIG-14-03). Journal of Clinical Oncology, 40(3), 282.
  • Kelliher, S., Ní Áinle, F., Weiss, L., Gamba, S., Fouhy, E., Marchetti, M., ... & Kevane, B. (2022). Analysis of the Platelet Proteome Reveals Insights into the Pro-Inflammatory and Pro-Thrombotic State Associated with the Philadelphia Chromosome-Negative Myeloproliferative Neoplasms. Blood, 140(Supplement 1), 2654-2655.
  • Cowzer, D., Zameer, M., Conroy, M., Kolch, W., & Duffy, A. G. (2022). Targeting KRAS in Pancreatic Cancer. Journal of Personalized Medicine, 12(11), 1870.
  • Mucci, L. A., Vinson, J., Gold, T., Gerke, T., Filipenko, J., Green, R. M., ... & IRONMAN Global Team. (2022). IRONMAN: A Novel International Registry of Men With Advanced Prostate Cancer. JCO Global Oncology, 8, e2200154.
  • Duffy, M. J., Mullooly, M., Bennett, K., & Crown, J. (2022). Vitamin D Supplementation: Does It Have a Preventative or Therapeutic Role in Cancer?. Nutrition and Cancer, 1-11.
  • McNevin, C. S., Cadoo, K., Baird, A. M., Finn, S. P., & McDermott, R. (2022). PARP Inhibitors in Advanced Prostate Cancer in Tumors with DNA Damage Signatures. Cancers, 14(19), 4751.
  • Carroll, H. K., Higgins, M. J., & O'Reilly, S. (2022). Trastuzumab Deruxtecan in HER2-Low Breast Cancer. The New England journal of medicine, 387(12), 1144.
  • Duffy, M. J., Tang, M., Rajaram, S., O’Grady, S., & Crown, J. (2022). Targeting Mutant p53 for Cancer Treatment: Moving Closer to Clinical Use?. Cancers, 14(18), 4499.
  • Powles, T., Tomczak, P., Park, S. H., Venugopal, B., Ferguson, T., Symeonides, S. N., … KEYNOTE-564 Investigators (2022). Pembrolizumab versus placebo as post-nephrectomy adjuvant therapy for clear cell renal cell carcinoma (KEYNOTE-564): 30-month follow-up analysis of a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet. Oncology, 23(9), 1133–1144. https://doi.org/10.1016/S1470-2045(22)00487-9
  • Duffy, M. J., & Crown, J. (2022). Circulating Tumor DNA as a Biomarker for Monitoring Patients with Solid Cancers: Comparison with Standard Protein Biomarkers. Clinical Chemistry, 68(11), 1381-1390.
  • Ding, X., Sharko, A. C., McDermott, M. S., Schools, G. P., Chumanevich, A., Ji, H., ... & Broude, E. V. (2022). Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo. Proceedings of the National Academy of Sciences, 119(32), e2201073119.
  • Mukherjee, N., Browne, A., Ivers, L., Santra, T., Cremona, M., Hennessy, B. T., ... & Eustace, A. J. (2022). A Systems Biology Approach to Investigate Kinase Signal Transduction Networks That Are Involved in Triple Negative Breast Cancer Resistance to Cisplatin. Journal of Personalized Medicine, 12(8), 1277.
  • Tang, M., O’Grady, S., Crown, J., & Duffy, M. J. (2022). MYC as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigations with the novel MYC inhibitor, MYCi975. Breast Cancer Research and Treatment, 195(2), 105-115.
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