Postdoctoral Researcher

Aoise O’Neill is a postdoctoral researcher in the Freeman Lab at the UCD Conway Institute. She earned her BSc in Industrial Biochemistry from the University of Limerick in 2018, and then spent two years in Vancouver, Canada, working at AbCellera Biologics. During her time there, she contributed to therapeutic antibody discovery for infectious diseases. Aoise returned to Ireland to pursue a PhD in tumour immunology at the University of Galway. Her PhD research focused on investigating post-translational modifications as drivers of stromal cell immunosuppression in colorectal cancer, with the goal of targeting this mechanism to reignite innate anti-tumour immunity within the tumour microenvironment.

Aoise’s current work explores the STING pathway as a novel immunotherapeutic target in osteosarcoma, investigating nanoparticle delivery of a STING activator in combination with chemotherapy to enhance anti-tumour immunity and improve disease outcomes.