The facility has a 600MHz and a 500MHz NMR equipped with probes for high sensitivity 1H analysis. A sample jet system attached to the 600MHz instrument enables high throughput analysis.
Nuclear Magnetic Resonance (NMR)
Nuclear magnetic resonance is a tool used to characterise small molecules. It is widely used by biological scientists to study both small and large biomolecules such as proteins and DNA. In this facility, NMR is used to study metabolism and in particular metabolites and lipoproteins.
Metabolomics
Metabolomics is the analysis of small molecules called metabolites in biological samples. Assessment of these metabolites can reveal information on metabolic pathways and alterations in different diseases and conditions.
Lipoprotein Profiling
Lipoproteins are particles made of lipids and proteins that transport water-insoluble lipids in the blood. Cholesterol and triglycerides are two types of lipids found in lipoproteins. The NMR based in vitro diagnostic research (IVDr) system was developed to quantify lipoproteins and lipoprotein subfractions, see the following class and subclasses:
- Main VLDL, IDL, LDL and HDL classes
- Six VLDL subclasses
- Six LDL sub-classes
- Four HDL-subclasses
To register your interest, contact:
Professor Lorraine Brennan
T: (+353-1) 716 6872
E: (opens in a new window)lorraine.brennan@ucd.ie