Proteomics is the large-scale study of proteins. All the proteins in a cell or tissue can be analysed in a single experiment. A researcher may want to identify the molecules present in a sample that they have isolated, or to compare the relative levels of proteins in samples from healthy and diseased tissue. We can also help analyse single molecules in detail: map protein modifications like phosphorylation or methylation, or identify interacting proteins and drug binding sites.
The Mass Spectrometry Resource is dedicated to biological mass spectrometry, the analytical technique capable of accurately determining the mass, charge and chemical structures of molecules. We offer the dedicated strategic support of our expert team, both before mass spectrometry (sample preparation and separation) and after (data analysis, bioinformatics) to enable our research and commercial partners to take full advantage of their results.
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Our instrumentation is capable of covering all aspects of modern proteomic science including quantitative proteomics, protein post-translational modifications and protein-protein interactions. We use two mass spectrometry platforms.
Guiding you to the various stages of experiment analysis, including protein identification and quantitation, statistical evaluation, data mining, and pathway analysis.
The Proteomics Core offer the dedicated strategic support of our expert team, both before mass spectrometry (sample preparation and separation) and after (data analysis, bioinformatics) to enable our research and commercial partners to take full advantage of their results. The approach to each research project is bespoke.
Please contact a member of the team (details below) to book your research project support appointment.
Given the nature of the facility, Core staff provide a full service offering and guide researchers at all stages of the experimental process. Please contact one of the team to initiate your bespoke proteomics solution.
(opens in a new window)Book a personal data analysis session with Prof. Matthias Wilm
Our team are involved in the delivery of both accredited graduate and continuing professional development modules to scientists
involved in proteomic research.
Prof. Matthias Wilm has extensive experience of mass spectrometry and proteomics. He contributed decisively to the development of proteomic techniques while he was at the European Molecular Biology Laboratory (EMBL).
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Over the course of his doctoral and postdoctoral studies, Eugene has amassed expertise across sample preparation, mass spectrometric methodology, data processing and downstream pathway analysis.
