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UCD Conway SPHERE Publication List


  1. Laura Twomey, Nastassia Navasiolava, Adrien Robin, Marie-Pierre Bareille, Guillemette Gauquelin-Koch, Arnaud Beck, Françoise Larcher, Gerardene Meade-Murphy, Sinead Sheridan, Patricia B. Maguire, Michael Harrison, Bernard Degryse, Niall M. Moyna, Claude Gharib, Marc-Antoine Custaud & Ronan P. Murphy A dry immersion model of microgravity modulates platelet phenotype, miRNA signature, and circulating plasma protein biomarker profile. Sci Rep 11, 21906 (2021). (opens in a new window)https://doi.org/10.1038/s41598-021-01335-x
  2. D. Swan, H. Enright, R. Desmond, G. Le, E. El Hassadi, B. Hennessy, F. Lynott, D. O'Keeffe, M. Crowley, L. Smyth, K. Perera, C. Jennings, F. Ni Ainle, J. Coll, K. Ryan, J. O'Donnell, M. Lavin, N. O'Connell, Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices, Thrombosis Update, 2021, 100086, ISSN 2666-5727, (opens in a new window)https://doi.org/10.1016/j.tru.2021.100086.
  3. O’Reilly, D., Murphy, C.A., Drew, R. et al. Platelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade. Pediatr Res (2021).
  4. Kelliher, S. and Falanga, A., 2021. Thrombosis in myeloproliferative neoplasms: A clinical and pathophysiological perspective. Thrombosis Update, p.100081. 
  5. Sholzberg, M., Tang, G.H., Rahhal, H., AlHamzah, M., Kreuziger, L.B., Áinle, F.N., Alomran, F., Alayed, K., Alsheef, M., AlSumait, F. and Pompilio, C.E., 2021. Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial. bmj375.
  6. Cullivan S, McCormack C, O’Callaghan M, et al. Characteristics of chronic thromboembolic pulmonary hypertension in Ireland. Pulmonary Circulation. October 2021. doi:(opens in a new window)10.1177/2045894021104870
  7. Murphy CA, O'Reilly DP, Edebiri O, Weiss L, Cullivan S, El-Khuffash A, Doyle E, Donnelly JC, Malone FD, Ferguson W, Drew RJ, O'Loughlin J, Neary E, Maguire PB, Kevane B, NíAinle F, McCallion N. Haematological parameters and coagulation in umbilical cord blood following COVID-19 infection in pregnancy. (opens in a new window)Eur J Obstet Gynecol Reprod Biol. 2021 Sep 21;266:99-105. doi: 10.1016/j.ejogrb.2021.09.019. Epub ahead of print. PMID: 34601263; PMCID: PMC8454187.
  8. Cullivan, S., Murphy, C. A., Weiss, L., Comer, S. P., Kevane, B., McCullagh, B., Maguire, P. B., Ainle, F.N., & Gaine, S. P. (2021). Platelets, extracellular vesicles and coagulation in pulmonary arterial hypertension. Pulmonary Circulation, 11(3), https://doi.org/10.1177/20458940211021036
  9. Comer, S. P., Cullivan, S., Szklanna, P. B., Weiss, L., Cullen, S., Kelliher, S., Smolenski, A., Murphy, C., Altaie, H., Curran, J., O'Reilly, K., Cotter, A. G., Marsh, B., Gaine, S., Mallon, P., McCullagh, B., Moran, N., Ainle, F. N., Kevane, B., Maguire, P. B., & Investigators, C. S. (2021). COVID-19 induces a hyperactive phenotype in circulating platelets. Plos Biology, 19(2), Article e3001109. (opens in a new window)https://doi.org/10.1371/journal.pbio.3001109
  10. Cremer, S. E., Catalfamo, J. L., Goggs, R., Seemann, S. E., Kristensen, A. T., Szklanna, P. B., Maguire, P. B., & Brooks, M. B. (2021). The canine activated platelet secretome (CAPS): A translational model of thrombin-evoked platelet activation response. Research and Practice in Thrombosis and Haemostasis, 5(1), 55-68. (opens in a new window)https://doi.org/10.1002/rth2.12450
  11. Othman, M., Cormier, M., Barnes, G. D., Comer, S. P., Connors, J. M., Denorme, F., Khorana, A. A., Casas, P. H. L., Morla, S., Muia, J., Ainle, F. N., Taylor, K. A., van der Wal, D. E., Weyand, A. C., Lavin, M., Registration, I., & Mkt, T. (2021). Harnessing Twitter to empower scientific engagement and communication: The ISTH 2020 virtual congress experience. Research and Practice in Thrombosis and Haemostasis, 5(2), 253-260. (opens in a new window)https://doi.org/10.1002/rth2.12478
  12. Sholzberg, M., Tang, G. H., Negri, E., Rahhal, H., Kreuziger, L. B., Pompilio, C. E., James, P., Fralick, M., AlHamzah, M., Alomran, F., Tseng, E., Lim, G., Lillicrap, D., Carrier, M., Ainle, F. N., Beckett, A., da Costa, B. R., Thorpe, K., Middeldorp, S., Lee, A., Cushman, M., & Juni, P. (2021). Coagulopathy of hospitalised COVID-19: A Pragmatic Randomised Controlled Trial of Therapeutic Anticoagulation versus Standard Care as a Rapid Response to the COVID-19 Pandemic (RAPID COVID COAG - RAPID Trial): A structured summary of a study protocol for a randomized controlled trial. Trials, 22(1), Article 202. (opens in a new window)https://doi.org/10.1186/s13063-021-05076-0
  13. Klok FA, Ageno W, Ay C, Bäck M, Barco S, Bertoletti L, Becattini C, Carlsen J, Delcroix M, van Es N, Huisman MV, Jara-Palomares L, Konstantinides S, Lang I, Meyer G, Ní Áinle F, Rosenkranz S, Pruszczyk P. State of the Art Review: "Optimal follow-up after acute pulmonary embolism: a position paper of the ESC Working Group on Pulmonary Circulation and Right Ventricular Function, in collaboration with the ESC Working Group on Atherosclerosis and Vascular Biology”; endorsed by the European Respiratory Society (ERS)" European Heart Journal 2021 (in press)
  14. Sholzberg M, Tang GT, Rahhal H, AlHamzah M, Baumann Kreuziger L, Ní Áinle F, Alomran F, Alayed K, Alsheef M, AlSumait F, Pompilio CE, Sperlich C, Tangri S, Tang T, Jaksa P, Suryanarayan D, Almarshoodi M, Castellucci L, James PD, Lillicrap D, Carrier M, Beckett A, Colovos C, Jayakar J, Arsenault M-P, Wu C, Doyon K, Andreou R, Dounaevskaia V, Tseng E, Lim G, Fralick M, Middeldorp S, Lee AYY, Zuo F, da Costa BR, Thorpe KE, Negri EM, Cushman M, Jüni P for the RAPID Trial investigators. Heparin for Moderately Ill Patients with Covid-19. medRxiv preprint (opens in a new window)https://doi.org/10.1101/2021.07.08.21259351
  15. Weiss L, Keaney J, Szklanna PB, Prendiville T, Uhrig W, Wynne K, Kelliher S, Ewins K, Comer SP, Egan K, O’Rourke E, Moran E, Petrov G, Patel A, Lennon A, Blanco A, Kevane B, Murphy S, Ní Áinle F*, Maguire PB*. (*Joint corresponding authors). Non-valvular atrial fibrillation patients anticoagulated with rivaroxaban compared with warfarin exhibit reduced circulating extracellular vesicles with attenuated pro-inflammatory protein signatures. J Thromb Haemost. 2021 in press
  16. Sklanna PB, Altaie H, Comer SP, Cullivan S, Kelliher S, Weiss L, Curran J, O’Reilly K, Cotter AG, Marsh B, Gaine S, Mallon P, McCullagh B, Ní Áinle F, Kevane B, Maguire P. Routine haematological parameters may be predictors of COVID-19 severity. Frontiers in Medicine 2021 (Accepted for publication)
  17. Barco S, Valerio L, Galli A, Turatti G, Mahmoudpour SH, Ageno W, Castellucci LA, Cesarman-Maus G, Ddungu H, De Paula EV, Dumantepe M, Goldhaber SZ, Guillermo Esposito MC, Klok FA, Kucher N, McLintock C, Ní Áinle F, Simioni P, Spirk D, Spyropoulos AC, Urano T, Zhai Z, Hunt B, Konstantinides SV. Global reporting of pulmonary embolism-related deaths in the WHO mortality database: vital registration data from 123 countries. Research and Practice in Thrombosis and Haemostasis 2021 doi:10.1002/rth2.12520 ​


  1. Murphy, C. A., O'Reilly, D. P., Neary, E., El-Khuffash, A., NiAinle, F., McCallion, N., & Maguire, P. B (2020). A review of the role of extracellular vesicles in neonatal physiology and pathology. Pediatric Research. https://doi.org/10.1038/s41390-020-01240-5
  2. Mooney, C., Eogan, M., Ainle, F. N., Cleary, B., Gallagher, J. J., O'Loughlin, J., & Drew, R. J (2020). Predicting bacteraemia in maternity patients using full blood count parameters: A supervised machine learning algorithm approach. International Journal of Laboratory Hematology. https://doi.org/10.1111/ijlh.13434
  3. Skeith, L., Blondon, M., & Ainle, F. N. (2020). Understanding and Preventing Placenta-Mediated Pregnancy Complications. Hamostaseologie, 40(03), 356-363. (opens in a new window)https://doi.org/10.1055/a-1184-8388
  4. Ainle, F. N., & Kevane, B. (2020). Which patients are at high risk of recurrent venous thromboembolism (deep vein thrombosis and pulmonary embolism)? Hematology-American Society of Hematology Education Program (1), 201-212. (opens in a new window)https://doi.org/10.1182/hematology.2020002268
  5. Andrew, L., Ainle, F. N., Blondon, M., Rodger, M. A., & Skeith, L. (2020). Preventing postpartum venous thromboembolism: A call to action to reduce undue maternal morbidity and mortality. Thrombosis Research, 193, 190-197. https://doi.org/10.1016/j.thromres.2020.07.007
  6. Ewins, K., & Ainle, F. N. (2020). VTE risk assessment in pregnancy. Research and Practice in Thrombosis and Haemostasis, 4(2), 183-192. https://doi.org/10.1002/rth2.12290
  7. Gleeson, E. M., Rehill, A. M., Fox, O. W., Ainle, F. N., McDonnell, C. J., Rushe, H. J., McCluskey, S., O'Donnell, J. S., & Preston, R. J. S. (2020). Apolipoprotein A-I enhances activated protein C cytoprotective activity. Blood Advances, 4(11), 2404-2408. https://doi.org/10.1182/bloodadvances.2019001316
  8. Hobohm, L., Keller, K., Valerio, L., Ainle, F. N., Klok, F. A., Munzel, T., Kucher, N., Lankeit, M., Konstantinides, S. V., & Barco, S. (2020). Fatality rates and use of systemic thrombolysis in pregnant women with pulmonary embolism. Esc Heart Failure, 7(5), 2365-2372. https://doi.org/10.1002/ehf2.12775
  9. Kelliher, S., Maguire, P. B., Szklanna, P. B., Weiss, L., Ewins, K., O'Doherty, R., Angelov, D., Ni Ainle, F., & Kevane, B. (2020). Pathophysiology of the Venous Thromboembolism Risk in Preeclampsia. Hamostaseologie, 40(05), 594-604. https://doi.org/10.1055/a-1162-3905
  10. Konstantinides, S. V., Meyer, G., Becattini, C., Bueno, H., Geersing, G. J., Harjola, V. P., Huisman, M. V., Humbert, M., Jennings, C. S., Jimenez, D., Kucher, N., Lang, I. M., Lankeit, M., Lorusso, R., Mazzolai, L., Meneveau, N., Ainle, F. N., Prandoni, P., Pruszczyk, P., Righini, M., Torbicki, A., Van Belle, E., & Zamorano, J. L. (2020). 2019 ESC Guidelines for the dignosis and management of acute pulmonary embolism development Toed in colaboration with the European Respiratory Society (ERS). European Heart Journal, 41(4), 543-603. https://doi.org/10.1093/eurheartj/ehz405
  11. Maguire, P. B., Parsons, M. E., Szklanna, P. B., Zdanyte, M., Munzer, P., Chatterjee, M., Wynne, K., Rath, D., Comer, S. P., Hayden, M., Ainle, F. N., & Gawaz, M. (2020). Comparative Platelet Releasate Proteomic Profiling of Acute Coronary Syndrome versus Stable Coronary Artery Disease. Frontiers in Cardiovascular Medicine, 7, Article 101. https://doi.org/10.3389/fcvm.2020.00101
  12. O'Flaherty, D., Enright, S., Ainle, F. N., & Hayes, N. (2020). Intraoperative cell salvage as part of a blood conservation strategy in an obstetric population with abnormal placentation at a large Irish tertiary referral centre: an observational study. Irish Journal of Medical Science, 189(3), 1053-1060. https://doi.org/10.1007/s11845-020-02182-x
  13. O'Shaughnessy, F., O'Reilly, D., & Ainle, F. N. (2020). Current opinion and emerging trends on the treatment, diagnosis, and prevention of pregnancy-associated venous thromboembolic disease: a review. Translational Research, 225, 20-32. https://doi.org/10.1016/j.trsl.2020.06.004
  14. Rosovsky, R. P., Sanfilippo, K. M., Wang, T. F., Rajan, S. K., Shah, S., Martin, K. A., Ainle, F. N., Huisman, M., Hunt, B. J., Kahn, S. R., Kevane, B., Lee, A. Y. Y., McLintock, C., & Kreuziger, L. B. (2020). Anticoagulation practice patterns in COVID-19: A global survey. Research and Practice in Thrombosis and Haemostasis, 4(6), 969-983. https://doi.org/10.1002/rth2.12414


  1. Szklanna, P. B., Parsons, M. E., Wynne, K., O'Connor, H., Egan, K., Allen, S., Ainle, F. N., & Maguire, P. B. (2019). The Platelet Releasate is Altered in Human Pregnancy. Proteomics Clinical Applications, 13(3), Article 1800162. https://doi.org/10.1002/prca.201800162
  2. Tardy, B., Buchmuller, A., Bistervels, I. M., Ainle, F. N., & Middeldorp, S. (2019). Thromboprophylaxis in pregnant women: For whom and which LMWH dosage? Journal of Thrombosis and Haemostasis, 17(8), 1401-1403. https://doi.org/10.1111/jth.14547
  3. Tardy, B., Chalayer, E., Kamphuisen, P. W., Ainle, F. N., Verhamme, P., Varlet, M. N., Chauleur, C., Rodger, M., Merah, A., Buchmuller, A., Bistervels, I., De Sancho, M. T., Middeldorp, S., Bertoletti, L., & Anticoagulatio, S. S. C. S. C. (2019). Definition of bleeding events in studies evaluating prophylactic antithrombotic therapy in pregnant women: A systematic review and a proposal from the ISTH SSC. Journal of Thrombosis and Haemostasis, 17(11), 1979-1988. https://doi.org/10.1111/jth.14576
  4. Ward, C. M., Andrews, R. K., Wolberg, A., Lip, G. Y. H., Eikelboom, J., De Meyer, S. F., Mast, A., Flick, M., Urano, T., Ny, T., Cutler, D., Ju, L. A., Zhu, C., Randi, A. M., O'Donnell, J. S., O'Brien, S. H., Fijnvandraat, K., Shima, M., Nathwani, A., Luyendyk, J., Vanhoorelbeke, K., Barco, S., Chuansumrit, A., Stanworth, S. J., Curry, N., Del Rio, J. M., Battinelli, E. M., Bos, M. H. A., Reinhardt, C., Peter, K., Gomez, K., Danese, E., Rak, J., Flaumenhaft, R., Di Paola, J., Nilsson, S., Severin, S., Eto, K., Hitchcock, I. S., Ni, H. Y., Despotovic, J., Boilard, E., Rondina, M., Mangin, P., Hamilton, J. R., Suzuki-Inoue, K., Tsukiji, N., Conway, E. M., Maas, C., Emsley, J., Jenne, C. N., Fuchs, T. A., Weitz, J., Johnsen, J. M., Rauova, L., Spyropoulos, A., Goto, S., Verhamme, P., Miranda, S., Rodger, M., Ainle, F., Schreiber, K., Thomas, M., Gal, G., Zentner, D., McLintock, C., Magnusson, M., & Speakers, I. S. A. (2019). Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia. Research and Practice in Thrombosis and Haemostasis, 3(3), 431-497. https://doi.org/10.1002/rth2.12225
  5. Dillon, A., Egan, K., Kevane, B., Galvin, Z., Maguire, P., Ni Ainle, F., & Stewart, S. (2019). Liver stiffness and thrombin generation in compensated cirrhosis. Research and Practice in Thrombosis and Haemostasis, 3(2), 291-297. https://doi.org/10.1002/rth2.12173
  6. Enright, S., Varadkar, S., Demaio, A., Flynn, C., Ainle, F. N., & Hehir, M. P. (2019). Antecedents of red cell transfusion in a large contemporary obstetric cohort. Journal of Perinatal Medicine, 47(2), 195-199. https://doi.org/10.1515/jpm-2018-0227
  7. Ewins, K., Ainle, F. N., Cheallaigh, C. N., Dunlea, E., Kelliher, S., Imbalzano, E., Bortoluzzi, C., Jou, I., Alfonso-Megido, J., Diaz-Pedroche, M. D., & Monreal, M. (2019). Higher Rates of Death and Major Bleeding Highlight the Inequities That Exist in the Care of People with Venous Thromboembolism Who Experience Social Exclusion: Findings from a Prospective Registry of 79735 Patients (RIETE). Blood, 134. https://doi.org/10.1182/blood-2019-130745
  8. Ewins, K., Ainle, F. N., Dunlea, E., Kelliher, S., Sandys, V., Rooney, H., Macken, L., & Cliona, N. C. (2019). Socially Excluded Persons in Ireland Have an Increased Annual Risk of Hospitalisation Due to Venous Thromboembolic Disease. Blood, 134. https://doi.org/10.1182/blood-2019-130371
  9. Grande, R., Dovizio, M., Marcone, S., Szklanna, P. B., Bruno, A., Ebhardt, H. A., Cassidy, H., Ainle, F. N., Caprodossi, A., Lanuti, P., Marchisio, M., Mingrone, G., Maguire, P. B., & Patrignani, P. (2019). Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells. Frontiers in Pharmacology, 10, Article 7. https://doi.org/10.3389/fphar.2019.00007
  10. Haire, G., Egan, K., Parmar, K., McKinnon, T., Monteith, C., O'Connor, H., Kevane, B., Maguire, P., Szklanna, P. B., Galligan, M., Donnelly, J. C., Allen, S., McCallion, N., Hunt, B., & Ainle, F. N. (2019). Alterations in fibrin formation and fibrinolysis in early onset-preeclampsia: Association with disease severity. European Journal of Obstetrics & Gynecology and Reproductive Biology, 241, 19-23. https://doi.org/10.1016/j.ejogrb.2019.07.035
  11. Hickey, A., Dunlea, E., & Ainle, F. N. (2019). A clinical audit investigating the use of venous thromboembolism (vte) risk assessments in the mater misericordiae university hospital (mmuh) and appropriate prescribing of prophylaxis. Irish Journal of Medical Science, 188, S34-S35.
  12. Kacprzyk, J., Parsons, M., Maguire, P. B., & Stewart, G. S. (2019). Examining gender effects in different types of undergraduate science assessment. Irish Educational Studies, 38(4), 467-480. https://doi.org/10.1080/03323315.2019.1645721
  13. Kelliher, S., Hall, P., Kevane, B., Dinu, D., Ewins, K., MacMahon, P., Ainle, F. N., & Breslin, T. (2019). Implementation of an acute DVT ambulatory care pathway in a large urban centre: current challenges and future opportunities. Thrombosis Journal, 17, Article 14. https://doi.org/10.1186/s12959-019-0203-y
  14. Kelliher, S., Weiss, L., Szklanna, P., Egan, K., Prendiville, T., Moran, E., Petrov, G., Blanco, A., Lennon, A., Murphy, S., Keaney, J., Ainle, F. N., & Maguire, P. (2019). Rivaroxaban Reduces the Levels of Extracellular Vesicles in Patients with Venous Thromboembolism and Non-Valvular Atrial Fibrillation. Blood, 134. https://doi.org/10.1182/blood-2019-126166
  15. Kevane, B., Day, M., Bannon, N., Lawler, L., Breslin, T., Andrews, C., Johnson, H., Fitzpatrick, M., Murphy, K., Mason, O., O'Neill, A., Donohue, F., & Ainle, F. N. (2019). Venous thromboembolism incidence in the Ireland east hospital group: a retrospective 22-month observational study. Bmj Open, 9(6), Article e030059. https://doi.org/10.1136/bmjopen-2019-030059
  16. Miller, I. S., Shiels, L. P., Buckley, G., Connor, K., Byrne, A. T., & Ainle, F. N. (2019). Interrogating the in vivo anti-metastatic action of tinzaparin and simvastatin in an orthotopic surgical resection mouse model of triple negative breast cancer. Cancer Research, 79(13). https://doi.org/10.1158/1538-7445.am2019-2012
  17. O'Brien, K. T., Golla, K., Kranjc, T., O'Donovan, D., Allen, S., Maguire, P., Simpson, J. C., O'Connell, D., Moran, N., & Shields, D. C. (2019). Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome. Plos One, 14(1), Article e0210337. https://doi.org/10.1371/journal.pone.0210337
  18. O'Shaughnessy, F., Donnelly, J. C., Bennett, K., Damkier, P., Ainle, F. N., & Cleary, B. J. (2019). Prevalence of postpartum venous thromboembolism risk factors in an Irish urban obstetric population. Journal of Thrombosis and Haemostasis, 17(11), 1875-1885. (opens in a new window)https://doi.org/10.1111/jth.14568


  1. Parsons, M. E. M., Szklanna, P. B., Guerrero, J. A., Wynne, K., Dervin, F., O'Connell, K., Allen, S., Egan, K., Bennett, C., McGuigan, C., Gheveart, C., Ainle, F. N., & Maguire, P. B. (2018). Platelet Releasate Proteome Profiling Reveals a Core Set of Proteins with Low Variance between Healthy Adults. Proteomics, 18(15), Article 1800219. https://doi.org/10.1002/pmic.201800219
  2. Haire, G., Egan, K., Kevane, B., Fay, M., Fortune, A., Savage, R., Doran, E., O'Neill, C., Walsh, K., Kenny, D., Lennon, A., Maguire, P., & Ainle, F. N. (2018). Characterization of Platelet Activation in Patients with Eisenmenger Syndrome. Blood, 132. https://doi.org/10.1182/blood-2018-99-116914
  3. Kevane, B., Allen, S., Walsh, K., Egan, K., Maguire, P. B., Galligan, M. C., Kenny, D., Savage, R., Doran, E., Lennon, A., Neary, E., & Ainle, F. N. (2018). Dual endothelin-1 receptor antagonism attenuates platelet-mediated derangements of blood coagulation in Eisenmenger syndrome. Journal of Thrombosis and Haemostasis, 16(8), 1572-1579. https://doi.org/10.1111/jth.14159
  4. Kevane, B., Day, M., Bannon, N., Lawler, L., Breslin, T., Andrews, C., Johnson, H., Fitzpatrick, M., Murphy, K., Mason, O., Kelliher, S., O'Neill, A., Donohue, F., & Ainle, F. N. (2018). Estimating the Burden of Hospital-Acquired Venous Thromboembolism: The Argument for Implementation of Mandatory Risk Reduction Strategies. Blood, 132. https://doi.org/10.1182/blood-2018-99-112143
  5. Kevane, B., & O'Connell, N. (2018). The current and future role of plasma-derived clotting factor concentrate in the treatment of haemophilia A. Transfusion and Apheresis Science, 57(4), 502-506. https://doi.org/10.1016/j.transci.2018.07.012
  6. Mac Mahon, C., McDonnell, M., Dunne, M., Crowne, M., Crumlish, J., O'Gorman, P., Brannagan, C., Roche, C., Greene, R., Fitzsimon, C., Deegan, C., Browne, J., Davenport, K., Coveney, S., Fortune, A., Ainle, F. N., Fay, M., Breslin, T., & Murphy, S. (2018). ANTICOAGULANT ASSOCIATED INTRACEREBRAL HAEMORRHAGE - A PROTOCOL TO REDUCE TIME TO TREATMENT. Age and Ageing, 47. https://doi.org/10.1093/ageing/afy140.111
  7. Maguire, P., Szklanna, P., Parsons, M., Wynne, K., O'Connor, H., O'Connell, K., Egan, K., McGuigan, C., Rickard, S., & Ainle, F. N. (2018). The Hundred-Person Platelet Releasate Project (100PREPs): A Barcode for Human Health and Disease. Blood, 132. https://doi.org/10.1182/blood-2018-99-115421
  8. Maguire, P. B., Donlon, T., Parsons, M., Wynne, K., Dillon, E., Ni Ainle, F., & Szklanna, P. B. (2018). Proteomic Analysis Reveals a Strong Association of beta-Catenin With Cadherin Adherens Junctions in Resting Human Platelets. Proteomics, 18(9), Article 1700419. https://doi.org/10.1002/pmic.201700419
  9. Monteith, C., Egan, K., O'Connor, H., Maguire, P., Kevane, B., Szklanna, P. B., Cooley, S., Malone, F., & Ainle, F. N. (2018). Early onset preeclampsia is associated with an elevated mean platelet volume (MPV) and a greater rise in MPV from time of booking compared with pregnant controls: results of the CAPE study. Journal of Perinatal Medicine, 46(9), 1010-1015. https://doi.org/10.1515/jpm-2017-0188
  10. O'Reilly, D., Egan, K., Burke, O., Griffiths, A., Neary, E., Blanco, A., Szklanna, P., Maguire, P., McCallion, N., & Ainle, F. N. (2018). The Population of Circulating Extracellular Vesicles Dramatically Alters after Very Premature Delivery-a Previously Unrecognised Postnatal Adaptation Process? Blood, 132. https://doi.org/10.1182/blood-2018-99-113180
  11. O'Shaughnessy, F., Donnelly, J., Cooley, S., Bennett, K., Ainle, F. N., & Cleary, B. (2018). Initiating postpartum pharmacological thromboprophylaxis: A comparison of international recommendations. American Journal of Obstetrics and Gynecology, 218(1), S493-S494.


  1. O'Shaughnessy, F., Donnelly, J. C., Cooley, S. M., Deering, M., Raman, A., Gannon, G., Hickey, J., Holland, A., Hayes, N., Bennett, K., Ainle, F. N., & Cleary, B. J. (2017). Thrombocalc: implementation and uptake of personalized postpartum venous thromboembolism risk assessment in a high-throughput obstetric environment. Acta Obstetricia Et Gynecologica Scandinavica, 96(11), 1382-1390. https://doi.org/10.1111/aogs.13206
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  1. O'Connor, H. D., Egan, K., Kevane, B., Malone, F. D., Cooley, S. M., Geary, M., Maguire, P. B., Szklanna, P., Tully, E. C., Neary, E., O'Loughlin, J., Allen, S., McCallion, N., & Ainle, F. N. (2016). Coagulation balance in early onset preeclampsia (EOP). American Journal of Obstetrics and Gynecology, 214(1), S408-S408. https://doi.org/10.1016/j.ajog.2015.10.829
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  7. Atzei, P., Maguire, P. B., Kennedy, B. N., & Moynagh, P. N. (2008). Cactin, a novel regulator of TLR signalling pathways. Journal of Neuroimmunology, 197(2), 162-162.
  8. Harmon, S., Preston, R. J. S., Ainle, F. N., Johnson, J. A., Cunningham, M. S., Smith, O. P., White, B., & O'Donnell, J. S. (2008). Dissociation of Activated Protein C Functions by Elimination of Protein S Cofactor Enhancement. Journal of Biological Chemistry, 283(45), 30531-30539. https://doi.org/10.1074/jbc.M802338200
  9. Johnson, J., Ainle, F. N., Harmon, S., O'Donnell, J. S., & Preston, R. J. S. (2008). A Single Amino Acid Substitution (I18V) in the Gla Domain of Activated Protein C Markedly Impairs Ability of PE and GlyCer to Enhance Anticoagulant Activity. Blood, 112(11), 1055-1055.
  10. Murphy, C., Crotty, F., Smyth, E. C., Healy, G., Breathnach, O. S., Grogan, L., Ainle, F. N., & Murphy, P. (2008). Alterations in serum prothrombotic markers induced by treatment with bevacizumab-based chemotherapy regimens. Journal of Clinical Oncology, 26(15). https://doi.org/10.1200/jco.2008.26.15_suppl.15034
  11. O'Riordan, A., Johnston, O., McMorrow, T., Wynne, K., Maguire, P., Hegarty, J. E., McCormick, A., Watson, A. J., Cagney, G., Gallagher, W. M., & Ryan, M. R. (2008). Identification of Apolipoprotein AI as a serum biomarker of chronic kidney disease in liver transplant recipients, using proteomic techniques. Proteomics Clinical Applications, 2(9), 1338-1348. (opens in a new window)https://doi.org/10.1002/prca.200780167


  2. Behan, A. T., Foy, M., Wynne, K., Clarke, M., Sullivan, M., Cotter, D. R., & Maguire, P. B. (2007). Analysis of membrane microdomain-associated proteins in the insular cortex of post-mortem human brain. Proteomics Clinical Applications, 1(10), 1324-1331. https://doi.org/10.1002/prca.200700047
  3. Coppinger, J. A., & Maguire, P. B. (2007). Insights into the platelet releasate. Current Pharmaceutical Design, 13(26), 2640-2646. https://doi.org/10.2174/138161207781662885
  4. Coppinger, J. A., O'Connor, R., Wynne, K., Flanagan, M., Sullivan, M., Maguire, P. B., Fitzgerald, D. J., & Cagney, G. (2007). Moderation of the platelet releasate response by aspirin. Blood, 109(11), 4786-4792. https://doi.org/10.1182/blood-2006-07-038539
  5. Costello, D., Tharmabala, M., Ainle, F. N., Spooner, M., Appleby, N., & Murphy, P. (2007). Risk factors and sequelae of cerebral vein thrombosis: A five year retrospective audit. Haematologica-the Hematology Journal, 92, 305-305.
  6. Foy, M., & Maguire, P. B. (2007). Recent advances in the characterisation of the platelet membrane system by proteomics. Current Pharmaceutical Design, 13(26), 2647-2655. https://doi.org/10.2174/138161207781662911
  7. Kerrigan, S. W., Jakubovics, N. S., Keane, C., Maguire, P., Wynne, K., Jenkinson, H. F., & Cox, D. (2007). Role of streptococcus gordonii surface proteins SspA/SspB and hsa in platelet function. Infection and Immunity, 75(12), 5740-5747. https://doi.org/10.1128/iai.00909-07
  8. Langabeer, S. E., Ainle, F. N., Conneally, E., & Lawler, M. (2007). Incidence and significance of the JAK2 V617F mutation in patients with chronic myeloproliferative disorders. Irish Journal of Medical Science, 176(2), 105-109. (opens in a new window)https://doi.org/10.1007/s11845-007-0026-x


  1. Ainle, F. N., Hayden, P. J., Crosby, P., Murphy, K., McCarthy, D., Kelly, J., & Neat, M. J. (2006). Concurrent rearrangement of BCL1 and BCL6 with a single immunoglobulin locus in a case of diffuse large B-cell lymphoma. Leukemia & Lymphoma, 47(12), 2655-2656. https://doi.org/10.1080/10428190600909586


  1. Kelly, P., Maguire, P. B., Bennett, M., Fitzgerald, D. J., Edwards, R. J., Thiede, B., Treumann, A., Collins, J. K., O'Sullivan, G. C., Shanahan, F., & Dunne, C. (2005). Correlation of probiotic Lactobacillus salivarius growth phase with its cell wall-associated proteorne. Fems Microbiology Letters, 252(1), 153-159. (opens in a new window)https://doi.org/10.1016/j.femsle.2005.08.051


  1. McRedmond, J. P., Park, S. D., Reilly, D. F., Coppinger, J. A., Maguire, P. B., Shields, D. C., & Fitzgerald, D. J. (2004). Integration of proteomics and genomics in platelets - A profile of platelet proteins and platelet-specific genes. Molecular & Cellular Proteomics, 3(2), 133-144. https://doi.org/10.1074/mcp.M300063-MCP200
  2. Coppinger, J. A., Cagney, G., Toomey, S., Kislinger, T., Belton, O., McRedmond, J. P., Cahill, D. J., Emili, A., Fitzgerald, D. J., & Maguire, P. B. (2004). Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood, 103(6), 2096-2104. https://doi.org/10.1182/blood-2003-08-2804
  3. Foy, M., Treumann, A., Fitzgerald, D. J., Maguire, P. B., & Kerrigan, S. K. (2004). Characterization of platelet lipid rafts leads to the identification of RGS-19, which forms a phosphorylation-dependent complex with 14-3-3 xi. Blood, 104(11), 181A-181A. (opens in a new window)https://doi.org/10.1182/blood.V104.11.625.625


  1. Maguire, P. B., Wynne, K. J., Harney, D. F., O'Donoghue, N. M., Stephens, G., & Fitzgerald, D. J. (2002). Identification of the phosphotyrosine proteome from thrombin activated platelets. Proteomics, 2(6), 642-648. (opens in a new window)https://doi.org/10.1002/1615-9861(200206)2:6<642::aid-prot642>3.0.co;2-i


  1. Ohlendieck, K., Fromming, G. R., Murray, B. E., Maguire, P. B., Leisner, E., Traub, I., & Pette, D. (1999). Effects of chronic low-frequency stimulation on Ca2+-regulatory membrane proteins in rabbit fast muscle. Pflugers Archiv-European Journal of Physiology, 438(5), 700-708. (opens in a new window)https://doi.org/10.1007/s004240051096


  1. Maguire, P. B., & Ohlendieck, K. (1996). Oligomerization of sarcoplasmic reticulum Ca2+-ATPase from rabbit skeletal muscle. Febs Letters, 396(2-3), 115-118. https://doi.org/10.1016/0014-5793(96)01106-4

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