The Charles Institute of Dermatology has several active research projects, spread across 5 different groups and categorized into 8 different thematic areas, which you can view below.
Inflammatory Skin Diseases Projects
Elucidation of the survival characteristics of immature melanocytes in the depigmenting skin disorders vitiligo
Systemic and pilo-sebaceous inflammation in hidradenitis suppurativa
Wound Healing and Wound Care Projects
Chronic wound repair via cell-free delivery of tailored ADSC-derived exosomes using an injectable hydrogel through polarizing M2 macrophages
Diabetic Wound Healing through an Injectable and Tuneable Extracellular Matrix Derived Hydrogel as a Stem Cell Delivery Niche
Mechanism study of the Cu(0)-mediated RDRP; Controlled polymerization of multivinyl monomers
Hyperbranched Poly(beta-amino ester)s based functionalised hydrogel scaffolds for wound healing
Design and development of an injectable hydrogel loaded with exosomes derived of AD-SCs for treatment of chronic skin wounds
Injectable hydrogel combining exosomes for chronic wound repair
Design and development of ECM-based material for wound healing applications
Rare Skin Diseases Projects
A Disruptive Gene Therapy Platform, Replacing viruses in the Treatment of Genetic Conditions (DTIF)
Multifunctional single-chain cyclized/knot polymers and their applications for Recessive Dystrophic Epidermolysis Bullosa (RDEB) wound healing
Investigate the interaction of top-performing non-viral vectors for gene therapy within live system
Development Of Gene-Editing Therapy To Restore Type Vii Collagen For The Treatment Of RDEB Using A Topical RNP Crispr System
Development of Novel Hyperbranched Poly(β-amino ester)s as a New Generation of Biodegradable Tissue Adhesive
Type VII collagen restoration in Recessive Dystrophic Epidermolysis Bullosa using a non-viral CRISPR gene-editing approach
Melanoma and other Skin Cancers Projects
Quantitative analysis of signaling pathway rewiring in melanocytes and melanomas mediated by microenvironmental cues and cell intrinsic factors
Investigations of the homeo-dynamic status of heterogeneous subpopulations of normal human cutaneous melanocytes: a paradigm for understanding melanoma-genesis.
Hair Growth Biology Projects
Discovery of autoantigens that trigger immune-mediated hair loss in Alopecia areata
Skin-Non-Skin Axes Projects
Skin biomarker study in Parkinsonian syndromes
Innovation & Consultancy Services Projects
Skin & Hair Pigmentation Projects
No active projects currently in this area.