| Professor Orina Belton |
Fitzsimons, S., Oggero, S., Bruen, R., McCarthy, C., Strowitzki, M. J., Mahon, N. G., et al. (2020). microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression. Frontiers in Immunology, 11.  |
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| Coveney, S., Murphy, S., Belton, O., Cassidy, T., Crowe, M., Dolan, E., et al. (2021). Inflammatory cytokines, high-sensitivity C-reactive protein, and risk of one-year vascular events, death, and poor functional outcome after stroke and transient ischemic attack. International Journal of Stroke. |
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| Coveney, S., Mccabe, J. J., Murphy, S., Belton, O., Gray, C., Cassidy, T., et al. (2021). Dose-Dependent Association of Inflammatory Cytokines with Carotid Atherosclerosis in Transient Ischaemic Attack: Implications for Clinical Trials. Cerebrovascular Diseases. |
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| Assoc Professor Oliver Blacque |
| Lange, K. I., Tsiropoulou, S., Kucharska, K., & Blacque, O. E. (2021). Interpreting the pathogenicity of joubert syndrome missense variants in caenorhabditis elegans. DMM Disease Models and Mechanisms, 14(1). |
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| Acker, N., Smith, H., Devine, C., Oltjen, S. L., Tsiropoulou, S., Smit-McBride, Z., et al. (2021). A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia. Proceedings of the National Academy of Sciences of the United States of America, 118(16). |
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| Park, K., Li, C., Tsiropoulou, S., Gonçalves, J., Kondratev, C., Pelletier, L., et al. (2021). CDKL kinase regulates the length of the ciliary proximal segment. Current Biology, 31(11), 2359-2373.e7. |
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| Dr Gary Brennan |
| Brennan, G. P., & Henshall, D. C. (2020). MicroRNAs as regulators of brain function and targets for treatment of epilepsy. Nature Reviews Neurology, 16(9), 506-519. |
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| Brennan, G. P., Bauer, S., Engel, T., Jimenez-Mateos, E. M., Del Gallo, F., Hill, T. D. M., et al. (2020). Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy.. Neurobiology of disease, 144, 105048. |
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| Casey, S., Goasdoue, K., Miller, S. M., Brennan, G. P., Cowin, G., O’Mahony, A. G., et al. (2020). Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury. Molecular Neurobiology, 57(10), 4322-4344. |
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| Conboy, K., Henshall, D. C., & Brennan, G. P. (2021). Epigenetic principles underlying epileptogenesis and epilepsy syndromes. Neurobiology of Disease, 148. |
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| Wilson, M. M., Henshall, D. C., Byrne, S. M., & Brennan, G. P. (2021). Chd2-related cns pathologies. International Journal of Molecular Sciences, 22(2), 1-20. |
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| Brennan, G. P., Garcia-Curran, M. M., Patterson, K. P., Luo, R., & Baram, T. Z. (2021). Multiple Disruptions of Glial-Neuronal Networks in Epileptogenesis That Follows Prolonged Febrile Seizures. Frontiers in Neurology, 12. |
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| Mathoux, J., Henshall, D. C., & Brennan, G. P. (2021). Regulatory Mechanisms of the RNA Modification m<sup>6</sup>A and Significance in Brain Function in Health and Disease. Frontiers in Cellular Neuroscience, 15. |
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| Reschke, C. R., Silva, L. F. A., Vangoor, V. R., Rosso, M., David, B., Cavanagh, B. L., et al. (2021). Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy. Molecular Therapy, 29(6), 2041-2052. |
|
| Dr Kieran Brennan |
| Brennan, K., Martin, K., FitzGerald, S. P., O’Sullivan, J., Wu, Y., Blanco, A., et al. (2020). A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum. Scientific Reports, 10(1). |
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| Professor Geraldine Butler |
| Pais, P., Califórnia, R., Galocha, M., Viana, R., Ola, M., Cavalheiro, M., et al. (2020). Candida glabrata transcription factor Rpn4 mediates fluconazole resistance through regulation of ergosterol biosynthesis and plasma membrane permeability. Antimicrobial Agents and Chemotherapy, 64(9). |
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| O’Brien, C., Oliveira-Pacheco, J., Cinnéide, E., Hasse, M., Hittinger, C. T., Rogers, T., et al. (2020). Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples. |
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| Mancera, E., Nocedal, I., Hammel, S., Gulati, M., Mitchell, K. F., Andes, D. R., et al. (2021). Evolution of the complex transcription network controlling biofilm formation in candida species. eLife, 10. |
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| O'Brien, C. E., Oliveira-Pacheco, J., Cinnéide, E., Haase, M. A. B., Hittinger, C. T., Rogers, T. R., et al. (2021). Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples. PLoS Pathogens, 17(3). |
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| Pekmezovic, M., Hovhannisyan, H., Gresnigt, M. S., Iracane, E., Oliveira-Pacheco, J., Siscar-Lewin, S., et al. (2021). Candida pathogens induce protective mitochondria-associated type I interferon signalling and a damage-driven response in vaginal epithelial cells. Nature Microbiology, 6(5), 643-657. |
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| Butler, G., Heitman, J., Idnurm, A., & James, T. Y. (2021). On a Special Collection in MMBR on Sex in Fungi: Molecular Mechanisms and Evolutionary Implications. Microbiology and molecular biology reviews : MMBR, 85(3), e0009421. |
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| Dr Annette Therese Byrne |
| O’Farrell, A. C., Jarzabek, M. A., Lindner, A. U., Carberry, S., Conroy, E., Miller, I. S., et al. (2020). Implementing systems modelling and molecular imaging to predict the efficacy of BCL-2 inhibition in colorectal cancer patient-derived xenograft models. Cancers, 12(10), 1-19. |
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| Connor, K., Murray, D. W., Jarzabek, M. A., Tran, N. L., White, K., Dicker, P., et al. (2020). Targeting the rhogef ßpix/cool-1 in glioblastoma: Proof of concept studies. Cancers, 12(12), 1-19. |
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| Barat, A., Smeets, D., Moran, B., Zhang, W., Cao, S., Das, S., et al. (2020). Combination of variations in inflammation- and endoplasmic reticulum-associated genes as putative biomarker for bevacizumab response in KRAS wild-type colorectal cancer. Scientific Reports, 10(1). |
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| White, K., Connor, K., Clerkin, J., Murphy, B. M., Salvucci, M., O'Farrell, A. C., et al. (2020). New hints towards a precision medicine strategy for IDH wild-type glioblastoma. Annals of Oncology, 31(12), 1679-1692. |
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| Woo, X. Y., Giordano, J., Srivastava, A., Zhao, Z. M., Lloyd, M. W., de Bruijn, R., et al. (2021). Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nature Genetics, 53(1), 86-99. |
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| Woo, X. Y., Giordano, J., Srivastava, A., Zhao, Z. M., Lloyd, M. W., de Bruijn, R., et al. (2021). Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (Nature Genetics, (2021), 53, 1, (86-99), 10.1038/s41588-020-00750-6). Nature Genetics, 53(5), 761. |
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| Assoc Professor Gerard Cagney |
| Mongan, D., Föcking, M., Healy, C., Susai, S. R., Heurich, M., Wynne, K., et al. (2021). Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence. JAMA Psychiatry, 78(1), 77-90. |
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| Heurich, M., Föcking, M., Mongan, D., Cagney, G., & Cotter, D. R. (2021). Dysregulation of complement and coagulation pathways: emerging mechanisms in the development of psychosis. Molecular Psychiatry. |
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| Dowling, C. M., Hollinshead, K. E. R., Di Grande, A., Pritchard, J., Zhang, H., Dillon, E. T., et al. (2021). Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer. Science Advances, 7(3). |
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| Föcking, M., Sabherwal, S., Cates, H. M., Scaife, C., Dicker, P., Hryniewiecka, M., et al. (2021). Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress. Molecular Psychiatry, 26(2), 524-533. |
|
| Dr Hilary Cassidy |
| Kumar, A., Mcgeogh, R., Cassidy, H., Ebhardt, H. A., & Sharma, V. (2020). CX3CR1 positive myeloid cells differentially regulate atherosclerotic vascular smooth muscle contraction by plc dependent activation of transient receptor potential cation (TRPC) channels. Atherosclerosis, 315, e32. |
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| Seidel, C., Zhernovkov, V., Cassidy, H., Kholodenko, B., Matallanas, D., Cosnier, F., & Gaté, L. (2021). Inhaled multi-walled carbon nanotubes differently modulate global gene and protein expression in rat lungs. Nanotoxicology, 15(2), 238-256. |
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| Royds, J., Cassidy, H., Conroy, M. J., Dunne, M. R., Lysaght, J., & McCrory, C. (2021). Examination and characterisation of the effect of amitriptyline therapy for chronic neuropathic pain on neuropeptide and proteomic constituents of human cerebrospinal fluid.. Brain, behavior, & immunity - health, 10, 100184. |
|
| Dr Colm Collins |
| Olli, K. E., Rapp, C., Connell, L. O., Collins, C. B., McNamee, E. N., Jensen, O., et al. (2020). Muc5ac expression protects the colonic barrier in experimental colitis. Inflammatory Bowel Diseases, 26(9), 1353-1367. |
|
| Dr Derek Costello |
| Jones, A. C., Pinki, F., Stewart, G. S., & Costello, D. A. (2021). Inhibition of Urea Transporter (UT)-B Modulates LPS-Induced Inflammatory Responses in BV2 Microglia and N2a Neuroblastoma Cells. Neurochemical Research, 46(6), 1322-1329. |
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| Assoc Professor John Crean |
| Monks, P., Wychowaniec, J. K., McKiernan, E., Clerkin, S., Crean, J., Rodriguez, B. J., et al. (2021). Spatiotemporally Resolved Heat Dissipation in 3D Patterned Magnetically Responsive Hydrogels. Small, 17(5). |
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| Professor William Gallagher |
| Wilkinson, M., Sinclair, P., Dellatorre-Teixeira, L., Swan, P., Brennan, E., Moran, B., et al. (2020). The molecular effects of a high fat diet on endometrial tumour biology. Life, 10(9), 1-17. |
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| Horgan, D., Ciliberto, G., Conte, P., Baldwin, D., Seijo, L., Montuenga, L. M., et al. (2020). Bringing Greater Accuracy to Europe's Healthcare Systems: The Unexploited Potential of Biomarker Testing in Oncology.. Biomedicine hub, 5(3), 182-223. |
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| Watson, W., Gonzalez, C., Russell, N., Azam, H., Corey, E., Morrissey, C., et al. (2020). Inhibition of serum response factor as a new strategy to overcome resistance to enzalutamide in prostate cancer. European Journal of Cancer, 138, S49. |
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| O’Farrell, A. C., Jarzabek, M. A., Lindner, A. U., Carberry, S., Conroy, E., Miller, I. S., et al. (2020). Implementing systems modelling and molecular imaging to predict the efficacy of BCL-2 inhibition in colorectal cancer patient-derived xenograft models. Cancers, 12(10), 1-19. |
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| Slater, K., Heeran, A. B., Garcia-Mulero, S., Kalirai, H., Sanz-Pamplona, R., Rahman, A., et al. (2020). High cysteinyl leukotriene receptor 1 expression correlates with poor survival of uveal melanoma patients and cognate antagonist drugs modulate the growth, cancer secretome, and metabolism of uveal melanoma cells. Cancers, 12(10), 1-27. |
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| Kearns, C., Burke, A., Gallagher, W. M., & Kelly, C. M. (2020). Patient-informed learning to assist development of personalised treatment care plans for breast cancer patients and survivors. European Journal of Cancer, 138, S69. |
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| Connor, K., Conroy, E., White, K., Shiels, L., Gallagher, W., Keek, S., et al. (2020). EXTH-30. EXPANDING THE UTILITY OF PRE-CLINICAL CONTRAST ENHANCED CT (CE-CT) FOR TUMOR DETECTION IN ORTHOTOPIC GBM MODELS USING RADIOMICS. Neuro-Oncology, 22(Supplement_2), ii93. |
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| Dwane, L., O'Connor, A. E., Das, S., Moran, B., Mulrane, L., Pinto-Fernandez, A., et al. (2020). A functional genomic screen identifies the deubiquitinase USP11 as a novel transcriptional regulator of ERa in breast cancer. Cancer Research, 80(22), 5076-5088. |
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| Watson, R. W., Azam, H., Aura, C., Russell, N., McCormack, J., Corey, E., et al. (2020). Inhibition of serum response factor improves response to enzalutamide in prostate cancer. Cancers, 12(12), 1-13. |
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| Barat, A., Smeets, D., Moran, B., Zhang, W., Cao, S., Das, S., et al. (2020). Combination of variations in inflammation- and endoplasmic reticulum-associated genes as putative biomarker for bevacizumab response in KRAS wild-type colorectal cancer. Scientific Reports, 10(1). |
|
| Genua, F., Mirkovic, B., Mullee, A., Levy, M., Gallagher, W. M., Vodicka, P., & Hughes, D. J. (2021). Association of circulating short chain fatty acid levels with colorectal adenomas and colorectal cancer. Clinical Nutrition ESPEN. |
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| Olsson Hau, S., Wahlin, S., Cervin, S., Falk, V., Nodin, B., Elebro, J., et al. (2021). PRR11 unveiled as a top candidate biomarker within the RBM3-regulated transcriptome in pancreatic cancer. Journal of Pathology: Clinical Research. |
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| Collins, D. M., Madden, S. F., Gaynor, N., AlSultan, D., Le Gal, M., Eustace, A. J., et al. (2021). Effects of HER family-targeting tyrosine kinase inhibitors on antibody-dependent cell-mediated cytotoxicity in HER2-expressing breast cancer. Clinical Cancer Research, 27(3), 807-818. |
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| Genua, F., Raghunathan, V., Jenab, M., Gallagher, W. M., & Hughes, D. J. (2021). The Role of Gut Barrier Dysfunction and Microbiome Dysbiosis in Colorectal Cancer Development. Frontiers in Oncology, 11. |
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| Eustace, A. J., Madden, S. F., Fay, J., Collins, D. M., Kay, E. W., Sheehan, K. M., et al. (2021). The role of infiltrating lymphocytes in the neo-adjuvant treatment of women with HER2-positive breast cancer. Breast Cancer Research and Treatment, 187(3), 635-645. |
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| Lynch, S. M., Russell, N. M., Barron, S., Wang, C. J. A., Loughman, T., Dynoodt, P., et al. (2021). Prognostic value of the 6-gene OncoMasTR test in hormone receptor–positive HER2-negative early-stage breast cancer: Comparative analysis with standard clinicopathological factors. European Journal of Cancer, 152, 78-89. |
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| Fitzgerald, J., Higgins, D., Mazo Vargas, C., Watson, W., Mooney, C., Rahman, A., et al. (2021). Future of biomarker evaluation in the realm of artificial intelligence algorithms: Application in improved therapeutic stratification of patients with breast and prostate cancer. Journal of Clinical Pathology, 74(7), 429-434. |
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| Doherty, T., McKeever, S., Al-Attar, N., Murphy, T., Aura, C., Rahman, A., et al. (2021). Feature fusion of Raman chemical imaging and digital histopathology using machine learning for prostate cancer detection. Analyst, 146(13), 4195-4211. |
|
| Dr Jana Haase |
| Kalinichenko, L. S., Mühle, C., Jia, T., Anderheiden, F., Datz, M., Eberle, A. L., et al. (2021). Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects. Molecular Psychiatry. |
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| Assoc Professor Chandralal Hewage |
| Timmons, P. B., & Hewage, C. M. (2020). HAPPENN is a novel tool for hemolytic activity prediction for therapeutic peptides which employs neural networks. Scientific Reports, 10(1). |
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| Timmons, P. B., & Hewage, C. M. (2021). ENNAACT is a novel tool which employs neural networks for anticancer activity classification for therapeutic peptides. Biomedicine and Pharmacotherapy, 133. |
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| Timmons, P. B., & Hewage, C. M. (2021). Biophysical study of the structure and dynamics of the antimicrobial peptide maximin 1. Journal of Peptide Science. |
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| Timmons, P. B., & Hewage, C. (2021). APPTEST is an innovative new method for the automatic prediction of peptide tertiary structures. |
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| Timmons, P. B., & Hewage, C. (2021). ENNAVIA is an innovative new method which employs neural networks for antiviral and anti-coronavirus activity prediction for therapeutic peptides. |
|
| Dr David Hughes |
| Genua, F., Mirkovic, B., Mullee, A., Levy, M., Gallagher, W. M., Vodicka, P., & Hughes, D. J. (2021). Association of circulating short chain fatty acid levels with colorectal adenomas and colorectal cancer. Clinical Nutrition ESPEN. |
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| Butt, J., Jenab, M., Werner, J., Fedirko, V., Weiderpass, E., Dahm, C. C., et al. (2021). Association of Pre-diagnostic Antibody Responses to Escherichia coli and Bacteroides fragilis Toxin Proteins with Colorectal Cancer in a European Cohort. Gut Microbes, 13(1), 1-14. |
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| Rothwell, J. A., Murphy, N., Beševic, J., Kliemann, N., Jenab, M., Ferrari, P., et al. (2021). Metabolic Signatures of Healthy Lifestyle Patterns and Colorectal Cancer Risk in a European Cohort. Clinical Gastroenterology and Hepatology. |
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| Aglago, E. K., Rinaldi, S., Freisling, H., Jiao, L., Hughes, D. J., Fedirko, V., et al. (2021). Soluble receptor for advanced glycation end-products (sRAGE) and colorectal cancer risk: A case-control study nested within a European prospective cohort. Cancer Epidemiology Biomarkers and Prevention, 30(1), 182-192. |
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| Outzen, M., Tjønneland, A., Hughes, D. J., Jenab, M., Frederiksen, K., Schomburg, L., et al. (2021). Toenail selenium, plasma selenoprotein P and risk of advanced prostate cancer: A nested case-control study. International Journal of Cancer, 148(4), 876-883. |
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| Genua, F., Raghunathan, V., Jenab, M., Gallagher, W. M., & Hughes, D. J. (2021). The Role of Gut Barrier Dysfunction and Microbiome Dysbiosis in Colorectal Cancer Development. Frontiers in Oncology, 11. |
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| Aglago, E. K., Schalkwijk, C. G., Freisling, H., Fedirko, V., Hughes, D. J., Jiao, L., et al. (2021). Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study. Carcinogenesis, 42(5), 705-713. |
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| Tsilidis, K. K., Papadimitriou, N., Dimou, N., Gill, D., Lewis, S. J., Martin, R. M., et al. (2021). Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: A Mendelian randomization study. American Journal of Clinical Nutrition, 113(6), 1490-1502. |
|
| Professor Breandán Kennedy |
| Slater, K., Heeran, A. B., Garcia-Mulero, S., Kalirai, H., Sanz-Pamplona, R., Rahman, A., et al. (2020). High cysteinyl leukotriene receptor 1 expression correlates with poor survival of uveal melanoma patients and cognate antagonist drugs modulate the growth, cancer secretome, and metabolism of uveal melanoma cells. Cancers, 12(10), 1-27. |
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| Kennedy, S. A., Morrissey, M. E., Dunne, M. R., O'Connell, F., Butler, C. T., Cathcart, M. C., et al. (2020). Combining 1,4-dihydroxy quininib with Bevacizumab/FOLFOX alters angiogenic and inflammatory secretions in ex vivo colorectal tumors. BMC Cancer, 20(1). |
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| Buckley, A. M., Dunne, M. R., Morrissey, M. E., Kennedy, S. A., Nolan, A., Davern, M., et al. (2020). Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib. Scientific Reports, 10(1). |
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| Sánchez, A. G., Álvarez, Y., Colligris, B., & Kennedy, B. (2021). Affordable and Effective Optokinetic Response Methods to Assess Visual Acuity and Contrast Sensitivity in Larval to Juvenile Zebrafish. |
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| Campiani, G., Cavella, C., Osko, J. D., Brindisi, M., Relitti, N., Brogi, S., et al. (2021). Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors. Journal of Medicinal Chemistry, 64(14), 9960-9988. |
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| Gómez Sánchez, A., Álvarez, Y., Colligris, B., & Kennedy, B. (2021). Affordable and effective optokinetic response methods to assess visual acuity and contrast sensitivity in larval to juvenile zebrafish. |
|
| Dr Karen Lange |
| Lange, K. I., Tsiropoulou, S., Kucharska, K., & Blacque, O. E. (2021). Interpreting the pathogenicity of joubert syndrome missense variants in caenorhabditis elegans. DMM Disease Models and Mechanisms, 14(1). |
|
| Professor Patricia Maguire |
| Kelliher, S., Maguire, P. B., Szklanna, P. B., Weiss, L., Ewins, K., O'Doherty, R., et al. (2020). Pathophysiology of the Venous Thromboembolism Risk in Preeclampsia. Hamostaseologie, 40(5), 594-604. |
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| O’Reilly, D., Murphy, C. A., Drew, R., El-Khuffash, A., Maguire, P. B., Ainle, F. N., & Mc Callion, N. (2021). Platelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade. Pediatric Research. |
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| Cremer, S. E., Catalfamo, J. L., Goggs, R., Seemann, S. E., Kristensen, A. T., Szklanna, P. B., et al. (2021). The canine activated platelet secretome (CAPS): A translational model of thrombin-evoked platelet activation response. Research and Practice in Thrombosis and Haemostasis, 5(1), 55-68. |
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| Murphy, C. A., Neary, E., O’Reilly, D. P., Cullivan, S., EL-Khuffash, A., NíAinle, F., et al. (2021). The role of the calibrated automated thrombogram in neonates: describing mechanisms of neonatal haemostasis and evaluating haemostatic drugs. European Journal of Pediatrics. |
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| Cullivan, S., Murphy, C. A., Weiss, L., Comer, S. P., Kevane, B., McCullagh, B., et al. (2021). Platelets, extracellular vesicles and coagulation in pulmonary arterial hypertension. Pulmonary Circulation, 11(3). |
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| Comer, S. P., Cullivan, S., Szklanna, P. B., Weiss, L., Cullen, S., Kelliher, S., et al. (2021). COVID-19 induces a hyperactive phenotype in circulating platelets. PLoS Biology, 19(2). |
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| Szklanna, P. B., Altaie, H., Comer, S. P., Cullivan, S., Kelliher, S., Weiss, L., et al. (2021). Routine Hematological Parameters May Be Predictors of COVID-19 Severity. Frontiers in Medicine, 8. |
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| Murphy, C. A., O’Reilly, D. P., Neary, E., EL-Khuffash, A., NíAinle, F., McCallion, N., & Maguire, P. B. (2021). A review of the role of extracellular vesicles in neonatal physiology and pathology. Pediatric Research, 90(2), 289-299. |
|
| Dr Simone Marcone |
| McCann, E., O'Sullivan, J., & Marcone, S. (2021). Targeting cancer-cell mitochondria and metabolism to improve radiotherapy response. Translational Oncology, 14(1). |
|
| Assoc Professor Siobhán McClean |
| Sainz-Mejías, M., Jurado-Martín, I., & McClean, S. (2020). Understanding Pseudomonas aeruginosa-Host Interactions: The Ongoing Quest for an Efficacious Vaccine. Cells, 9(12). |
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| Schijns, V., Majhen, D., Van Der Ley, P., Thakur, A., Summerfield, A., Berisio, R., et al. (2021). Rational vaccine design in times of emerging diseases: The critical choices of immunological correlates of protection, vaccine antigen and immunomodulation. Pharmaceutics, 13(4). |
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| Jurado-Martín, I., Sainz-Mejías, M., & McClean, S. (2021). Pseudomonas aeruginosa: An audacious pathogen with an adaptable arsenal of virulence factors. International Journal of Molecular Sciences, 22(6), 1-37. |
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| Pither, M. D., McClean, S., Silipo, A., Molinaro, A., & Di Lorenzo, F. (2021). A chronic strain of the cystic fibrosis pathogen Pandoraea pulmonicola expresses a heterogenous hypo-acylated lipid A. Glycoconjugate Journal, 38(2), 135-144. |
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| Ma, C., & McClean, S. (2021). Mapping global prevalence of acinetobacter baumannii and recent vaccine development to tackle it. Vaccines, 9(6). |
|
| Assoc Professor Margaret McGee |
| Brennan, K., Martin, K., FitzGerald, S. P., O’Sullivan, J., Wu, Y., Blanco, A., et al. (2020). A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum. Scientific Reports, 10(1). |
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| Wu, Y., Brennan, K., Fernández, A. B., & Mc Gee, M. M. (2021). Cyclophilin A regulates secretion of tumour-derived extracellular vesicles. Translational Oncology, 14(8). |
|
| Professor Wim Meijer |
| Ballesté, E., Demeter, K., Masterson, B., Timoneda, N., Sala-Comorera, L., & Meijer, W. G. (2020). Implementation and integration of microbial source tracking in a river watershed monitoring plan. Science of the Total Environment, 736. |
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| Reynolds, L. J., Sala-Comorera, L., Martin, N. A., Nolan, T. M., Stephens, J. H., Gitto, A., et al. (2020). Correlation between antimicrobial resistance and faecal contamination in small urban streams and bathing waters. Science of the Total Environment, 739. |
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| Reynolds, L. J., Martin, N. A., Sala-Comorera, L., Callanan, K., Doyle, P., O’Leary, C., et al. (2021). Identifying Sources of Faecal Contamination in a Small Urban Stream Catchment: A Multiparametric Approach. Frontiers in Microbiology, 12. |
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| Sala-Comorera, L., Nolan, T. M., Reynolds, L. J., Venkatesh, A., Cheung, L., Martin, N. A., et al. (2021). Bacterial and Bacteriophage Antibiotic Resistance in Marine Bathing Waters in Relation to Rivers and Urban Streams. Frontiers in Microbiology, 12. |
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| Sala-Comorera, L., Reynolds, L. J., Martin, N. A., O'Sullivan, J. J., Meijer, W. G., & Fletcher, N. F. (2021). Decay of infectious SARS-CoV-2 and surrogates in aquatic environments. Water Research, 201. |
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| Brandão, J., Gangneux, J. P., Arikan-Akdagli, S., Barac, A., Bostanaru, A. C., Brito, S., et al. (2021). Mycosands: Fungal diversity and abundance in beach sand and recreational waters — Relevance to human health. Science of the Total Environment, 781. |
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| Furuta, Y., Cheng, C., Zorigt, T., Paudel, A., Izumi, S., Tsujinouchi, M., et al. (2021). Direct regulons of atxa, the master virulence regulator of bacillus anthracis. mSystems, 6(4). |
|
| Dr Steven Middleton |
| Chen, S., He, L., Huang, A. J. Y., Boehringer, R., Robert, V., Wintzer, M. E., et al. (2020). A hypothalamic novelty signal modulates hippocampal memory. Nature, 586(7828), 270-274. |
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| Professor Cormac Murphy |
| Gimenez, D., Phelan, A., Murphy, C. D., & Cobb, S. L. (2021). <sup>19</sup>F NMR as a tool in chemical biology. Beilstein Journal of Organic Chemistry, 17, 293-318. |
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| Khan, M. F., & Murphy, C. D. (2021). Bacterial degradation of the anti-depressant drug fluoxetine produces trifluoroacetic acid and fluoride ion. Applied Microbiology and Biotechnology. |
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| Khan, M. F., & Murphy, C. D. (2021). 3-Hydroxytyrosol regulates biofilm growth in Cunninghamella elegans. Fungal Biology, 125(3), 211-217. |
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| Gimenez, D., Phelan, A., Murphy, C. D., & Cobb, S. L. (2021). Fengycin A Analogues with Enhanced Chemical Stability and Antifungal Properties. Organic Letters, 23(12), 4672-4676. |
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| Dr Tanja Narancic |
| Narancic, T., Salvador, M., Hughes, G. M., Beagan, N., Abdulmutalib, U., Kenny, S. T., et al. (2021). Genome analysis of the metabolically versatile Pseudomonas umsongensis GO16: the genetic basis for PET monomer upcycling into polyhydroxyalkanoates. Microbial Biotechnology. |
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| Tiso, T., Narancic, T., Wei, R., Pollet, E., Beagan, N., Schröder, K., et al. (2021). Towards bio-upcycling of polyethylene terephthalate. Metabolic Engineering, 66, 167-178. |
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| Assoc Professor David O'Connell |
| McGauran, G., Dorris, E., Borza, R., Morgan, N., Shields, D. C., Matallanas, D., et al. (2020). Resolving the Interactome of the Human Macrophage Immunometabolism Regulator (MACIR) with Enhanced Membrane Protein Preparation and Affinity Proteomics. Proteomics, 20(19-20). |
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| Reiter, T., Pajenda, S., O'Connell, D., Lynch, C., Kapps, S., Agis, H., et al. (2021). Renal Expression of Light Chain Binding Proteins. Frontiers in Medicine, 7. |
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| Professor Kevin O'Connor |
| Guzik, M. W., Duane, G. F., Kenny, S. T., Casey, E., Mielcarek, P., Wojnarowska, M., & O’Connor, K. E. (2021). A polyhydroxyalkanoates bioprocess improvement case study based on four fed-batch feeding strategies. Microbial Biotechnology. |
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| Narancic, T., Salvador, M., Hughes, G. M., Beagan, N., Abdulmutalib, U., Kenny, S. T., et al. (2021). Genome analysis of the metabolically versatile Pseudomonas umsongensis GO16: the genetic basis for PET monomer upcycling into polyhydroxyalkanoates. Microbial Biotechnology. |
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| O'connor, K. E. (2021). Microbiology challenges and opportunities in the circular economy. Microbiology (United Kingdom), 167(1), 1-3. |
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| Malagurski, I., Frison, R., Maurya, A. K., Neels, A., Andjelkovic, B., Senthamaraikannan, R., et al. (2021). Polyhydroxyoctanoate films reinforced with titanium dioxide microfibers for biomedical application. Materials Letters, 285. |
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| Pekmezovic, M., Krusic, M. K., Malagurski, I., Milovanovic, J., Stepien, K., Guzik, M., et al. (2021). Polyhydroxyalkanoate/antifungal polyene formulations with monomeric hydroxyalkanoic acids for improved antifungal efficiency. Antibiotics, 10(6). |
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| Tiso, T., Narancic, T., Wei, R., Pollet, E., Beagan, N., Schröder, K., et al. (2021). Towards bio-upcycling of polyethylene terephthalate. Metabolic Engineering, 66, 167-178. |
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| Dr Niamh O'Sullivan |
| Fowler, P. C., Byrne, D. J., Blackstone, C., & O’sullivan, N. C. (2020). Loss of the mitochondrial fission GTPase Drp1 contributes to neurodegeneration in a drosophila model of hereditary spastic paraplegia. Brain Sciences, 10(9), 1-18. |
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| Dr Maria Prencipe |
| Kumari, P., Pillai, V. V. S., Rodriguez, B. J., Prencipe, M., & Benedetto, A. (2020). Sub-toxic concentrations of ionic liquids enhance cell migration by reducing the elasticity of the cellular lipid membrane. Journal of Physical Chemistry Letters, 11(17), 7327-7333. |
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| Watson, W., Gonzalez, C., Russell, N., Azam, H., Corey, E., Morrissey, C., et al. (2020). Inhibition of serum response factor as a new strategy to overcome resistance to enzalutamide in prostate cancer. European Journal of Cancer, 138, S49. |
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| Watson, R. W., Azam, H., Aura, C., Russell, N., McCormack, J., Corey, E., et al. (2020). Inhibition of serum response factor improves response to enzalutamide in prostate cancer. Cancers, 12(12), 1-13. |
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| Dr Helen Reid |
| Mulvaney, E. P., Reid, H. M., Bialesova, L., Mendes-Ferreira, P., Adão, R., Brás-Silva, C., & Kinsella, B. T. (2020). Efficacy of the thromboxane receptor antagonist NTP42 alone, or in combination with sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension. European Journal of Pharmacology, 889. |
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| Dr Emmanuel Reynaud |
| de Niz, M., Kehrer, J., Brancucci, N. M. B., Moalli, F., Reynaud, E. G., Stein, J. V., & Frischknecht, F. (2020). 3D imaging of undissected optically cleared Anopheles stephensi mosquitoes and midguts infected with Plasmodium parasites. PLoS ONE, 15(9 September). |
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| Torres-Leguizamon, M., Reynaud, E., Nefau, T., & Duplessy-Garson, C. (2020). La reduction des risques a distance, un programme adapte et efficace pour faire face a la pandemie de COVID-19. Psychotropes (Paris, France), 26, 123-137. |
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| Monks, P., Wychowaniec, J. K., McKiernan, E., Clerkin, S., Crean, J., Rodriguez, B. J., et al. (2021). Spatiotemporally Resolved Heat Dissipation in 3D Patterned Magnetically Responsive Hydrogels. Small, 17(5). |
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| Merces, G. O. T., Kennedy, C., Lenoci, B., Reynaud, E. G., Burke, N., & Pickering, M. (2021). The incubot: A 3D printer-based microscope for long-term live cell imaging within a tissue culture incubator. HardwareX, 9. |
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| Dr Michelle Rich |
| Copp, J. N., Pletzer, D., Brown, A. S., Van der Heijden, J., Miton, C. M., Edgar, R. J., et al. (2020). Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections.. mBio, 11(5). |
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| Hall, K. R., Robins, K. J., Williams, E. M., Rich, M. H., Calcott, M. J., Copp, J. N., et al. (2020). Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues.. eLife, 9. |
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| Sharrock, A. V., McManaway, S. P., Rich, M. H., Mumm, J. S., Hermans, I. F., Tercel, M., et al. (2021). Engineering the <i>Escherichia coli</i> Nitroreductase NfsA to Create a Flexible Enzyme-Prodrug Activation System.. Frontiers in pharmacology, 12, 701456. |
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| Rich, M. H., Sharrock, A. V., Ashoorzadeh, A., Patterson, A. V., Smaill, J. B., & Ackerley, D. F. (2021). Directed evolution of the B. subtilis nitroreductase YfkO improves activation of the PET-capable probe SN33623 and CB1954 prodrug.. Biotechnology letters, 43(1), 203-211. |
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| Dr Laura Sala-Comorera |
| Ballesté, E., Demeter, K., Masterson, B., Timoneda, N., Sala-Comorera, L., & Meijer, W. G. (2020). Implementation and integration of microbial source tracking in a river watershed monitoring plan. Science of the Total Environment, 736. |
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| Reynolds, L. J., Sala-Comorera, L., Martin, N. A., Nolan, T. M., Stephens, J. H., Gitto, A., et al. (2020). Correlation between antimicrobial resistance and faecal contamination in small urban streams and bathing waters. Science of the Total Environment, 739. |
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| Sala-Comorera, L., Caudet-Segarra, L., Galofré, B., Lucena, F., Blanch, A. R., & García-Aljaro, C. (2020). Unravelling the composition of tap and mineral water microbiota: Divergences between next-generation sequencing techniques and culture-based methods. International Journal of Food Microbiology, 334. |
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| Ballesté, E., Blanch, A. R., Mendez, J., Sala-Comorera, L., Maunula, L., Monteiro, S., et al. (2021). Bacteriophages Are Good Estimators of Human Viruses Present in Water. Frontiers in Microbiology, 12. |
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| Reynolds, L. J., Martin, N. A., Sala-Comorera, L., Callanan, K., Doyle, P., O’Leary, C., et al. (2021). Identifying Sources of Faecal Contamination in a Small Urban Stream Catchment: A Multiparametric Approach. Frontiers in Microbiology, 12. |
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| Sala-Comorera, L., Nolan, T. M., Reynolds, L. J., Venkatesh, A., Cheung, L., Martin, N. A., et al. (2021). Bacterial and Bacteriophage Antibiotic Resistance in Marine Bathing Waters in Relation to Rivers and Urban Streams. Frontiers in Microbiology, 12. |
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| Sala-Comorera, L., Reynolds, L. J., Martin, N. A., O'Sullivan, J. J., Meijer, W. G., & Fletcher, N. F. (2021). Decay of infectious SARS-CoV-2 and surrogates in aquatic environments. Water Research, 201. |
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| Dr Julen Tomás Cortázar |
| Trentelman, J. J. A., Sima, R., Krezdorn, N., Tomás-Cortázar, J., Barriales, D., Takumi, K., et al. (2020). A combined transcriptomic approach to identify candidates for an anti-tick vaccine blocking B. afzelii transmission.. Scientific reports, 10(1), 20061. |
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| Knorr, S., Reissert-Oppermann, S., Tomás-Cortázar, J., Barriales, D., Azkargorta, M., Iloro, I., et al. (2021). Identification and Characterization of Immunodominant Proteins from Tick Tissue Extracts Inducing a Protective Immune Response against <i>Ixodes ricinus</i> in Cattle.. Vaccines, 9(6). |
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| Trentelman, J. J. A., Tomás-Cortázar, J., Knorr, S., Barriales, D., Hajdusek, O., Sima, R., et al. (2021). Probing an Ixodes ricinus salivary gland yeast surface display with tick-exposed human sera to identify novel candidates for an anti-tick vaccine.. Scientific reports, 11(1), 15745. |
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| Dr Dieter Waschbusch |
| Waschbüsch, D., & Khan, A. R. (2020). Phosphorylation of Rab GTPases in the regulation of membrane trafficking.. Traffic (Copenhagen, Denmark), 21(11), 712-719. |
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| Waschbüsch, D., Berndsen, K., Lis, P., Knebel, A., Lam, Y. P. Y., Alessi, D. R., & Khan, A. R. (2021). Structural basis for the specificity of PPM1H phosphatase for Rab GTPases. EMBO Reports. |
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| McGrath, E., Waschbüsch, D., Baker, B. M., & Khan, A. R. (2021). LRRK2 binds to the Rab32 subfamily in a GTP-dependent manner <i>via</i> its armadillo domain.. Small GTPases, 12(2), 133-146. |
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| Waschbüsch, D., Purlyte, E., & Khan, A. R. (2021). Dual arginine recognition of LRRK2 phosphorylated Rab GTPases.. Biophysical journal, 120(9), 1846-1855. |
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| Dr Yan Yan |
| Boselli, L., Lopez, H., Zhang, W., Cai, Q., Giannone, V. A., Li, J., et al. (2020). Classification and biological identity of complex nano shapes. Communications Materials, 1(1). |
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| Dawson, K. A., & Yan, Y. (2021). Current understanding of biological identity at the nanoscale and future prospects. Nature Nanotechnology, 16(3), 229-242. |
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| Boselli, L., Lopez, H., Zhang, W., Cai, Q., Giannone, V. A., Li, J., et al. (2021). Author Correction: Classification and biological identity of complex nano shapes. Communications Materials, 2(1). |
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| Wang, Y. -F., Zhang, C., Yang, K., Wang, Y., Shan, S., Yan, Y., et al. (2021). Transportation of AIE-visualized nanoliposomes is dominated by the protein corona. National Science Review, 8(6). |
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