Biomolecular and Biomedical Science

School of Biomolecular and Biomedical Science - Research Publications 2022/23

Below is the list of research publications for the School of Biomolecular and Biomedical Science in the academic year 2022/23.



Chapter

Dr Gary Brennan

Quinlan, S., Henke, C., Brennan, G. P., Henshall, D. C., & Jimenez-Mateos, E. M. (2023). Detection of MicroRNAs in Brain Slices Using In Situ Hybridization. In Methods in Molecular Biology (Vol. 2595, pp. 93-100). doi:10.1007/978-1-0716-2823-2_6

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Dr Hilary Cassidy

Gaspar, V. I., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). In vitro-, ecological-, murine, and human models for examining the effects of EDCs. In Environmental Contaminants and Endocrine Health (pp. 45-53). doi:10.1016/B978-0-12-824464-7.00024-6

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Ms Harsha Ganesan

Shruthi, N. R., Jain, M. S., Ganesan, H., Banerjee, A., Zhang, H., Sun, X. F., & Pathak, S. (2023). Drug Repurposing in Cancer. In Drug Repurposing for Emerging Infectious Diseases and Cancer (pp. 159-179). doi:10.1007/978-981-19-5399-6_8

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Assoc Professor Carmel Hensey

Azzi, A. M., Bartoli, G., Boscoboinik, D., Hensey, C., & Szewczyk, A. (2023). a-Tocopherol and Protein Kinase C Regulation of Intracellular Signaling. In Vitamin E in Health and Disease (pp. 371-384). doi:10.1201/9781003418160-35

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Dr Mohd Faheem Khan

Khan, M. F., & Murphy, C. D. M. (2023). Environmental Remediation by Novel Nanomaterials and Fungi with High-degradation Capacity of Hazardous Contaminants. In Bio and Nanoremediation of Hazardous Environmental Pollutants (pp. 283-310). doi:10.1201/9781003052982-14

Available Online
 

Luqueño, F. F., López-Valdez, F., & Pérez, G. M. (n.d.). Bio and Nanoremediation of Hazardous Environmental Pollutants. CRC Press. doi:10.1201/9781003052982

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Professor Patricia Maguire

Szklanna, P. B., Weiss, L., Namee, B. M., Faryal, R., Kevane, B., Áinle, F. N., & Maguire, P. B. (2023). AI in Haematology. In AI in Clinical Medicine: A Practical Guide for Healthcare Professionals (pp. 184-191). doi:10.1002/9781119790686.ch18

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Assoc Professor Tara McMorrow

Gaspar, V. I., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). In vitro-, ecological-, murine, and human models for examining the effects of EDCs. In Environmental Contaminants and Endocrine Health (pp. 45-53). doi:10.1016/B978-0-12-824464-7.00024-6

Available Online
 
Dr Jennifer Mitchell

Mitchell, J. (2023). ISBN: 978-1-910963-67-8. In L. Padden, D. Elliot, J. Tonge, & L. Hyland (Eds.), Learning from UDL Leaders: UCD University for All Faculty Partner Case Studies. Ireland: UCD Access & Lifelong Learning.

 
Professor Cormac Murphy

Khan, M. F., & Murphy, C. D. M. (2023). Environmental Remediation by Novel Nanomaterials and Fungi with High-degradation Capacity of Hazardous Contaminants. In Bio and Nanoremediation of Hazardous Environmental Pollutants (pp. 283-310). doi:10.1201/9781003052982-14

Available Online
 

Luqueño, F. F., López-Valdez, F., & Pérez, G. M. (n.d.). Bio and Nanoremediation of Hazardous Environmental Pollutants. CRC Press. doi:10.1201/9781003052982

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Dr Emmanuel Reynaud

Walter, A., Slezak, P., Mueller, R., & Kerckhofs, G. (Eds.) (2023). Bioimaging in Tissue Engineering and Regeneration. In . Springer International Publishing. doi:10.1007/978-3-030-85569-7

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Dr Craig Slattery

Gaspar, V. I., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). In vitro-, ecological-, murine, and human models for examining the effects of EDCs. In Environmental Contaminants and Endocrine Health (pp. 45-53). doi:10.1016/B978-0-12-824464-7.00024-6

Available Online
 
Dr Luisa Weiss

Szklanna, P. B., Weiss, L., Namee, B. M., Faryal, R., Kevane, B., Áinle, F. N., & Maguire, P. B. (2023). AI in Haematology. In AI in Clinical Medicine: A Practical Guide for Healthcare Professionals (pp. 184-191). doi:10.1002/9781119790686.ch18

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Conference Paper

Dr Derek Costello

Galvin, D., Woods, M., McCormack, C., Paulose, A., Creaven, B., & Costello, D. (2023). A novel therapy for the treatment of TLR mediated neuroinflammation. In Brain and Neuroscience Advances Vol. 7 (pp. 156). Brighton, UK: SAGE Publishing. doi:10.1177/23982128231180246

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Ralph, A., Fitzsimons, A., Galvin, D., Creaven, B., Blacque, O., & Costello, D. (2023). Investigating a novel coumarin-derivative in models of Alzheimer’s disease in vitro and in vivo. In Brain and Neuroscience Advances Vol. 7 (pp. 157). Brighton, UK: SAGE Publishing. doi:10.1177/2398212823118024

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Abstract (2019). In Brain and Neuroscience Advances Vol. 3. SAGE Publications. doi:10.1177/2398212819855490

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Dr Jessica Davis

Clerkin, S., Wychowaniec, J. K., Singh, K., Davis, J. L., Treacy, N. J., Krupa, I., et al. (2023). UTILITY OF GELATIN METHACRYLOYL (GELMA) HYDROGELS AS TUNEABLE BIOPHYSICAL SCAFFOLDS FOR THE DERIVATION OF HIPSC-DERIVED KIDNEY ORGANOIDS. In TISSUE ENGINEERING PART A Vol. 29 (pp. 1523).

 
Dr Joanna Drabinska

Duggan, N., O’Donoghue, É., Drabinksa, J., Schaffer, K., & McClean, S. (2023). P234 Investigating the role of hypoxia in driving the adaptation of Mycobacterium abscessus infection in cystic fibrosis. In Journal of Cystic Fibrosis Vol. 22 (pp. S137). Elsevier BV. doi:10.1016/s1569-1993(23)00606-9

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Drabinska, J., Mazhova, A., Duggan, N., & McClean, S. (2023). WS07.03 A long-term study of Pseudomonas aeruginosa early patient isolate adaptation to the hypoxic environment. In Journal of Cystic Fibrosis Vol. 22 (pp. S14-S15). Elsevier BV. doi:10.1016/s1569-1993(23)00225-4

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Assoc Professor Caroline Herron

Gil, B., & Herron, C. (2023). CANNABIDIOLIC ACID TREATMENT REVERSES DEFICITS IN SYNAPTIC PLASTICITY IN HIPPOCAMPAL SLICES FROM THE APP/PS1 MOUSE MODEL OF ALZHEIMER'S DISEASE. In 32nd Annual Symposium on the Cannabinoids, International Cannabinoid Research Society, Research Triangle Park, NC, USA Vol. 32 (pp. 149). Galway, Ireland: International Cannabinoid Research Society.

 
Professor Breandán Kennedy

Brugnera, M., Messina, F., Reynolds, A., O'Reilly, N., Kalesnykas, G., Herrero-Vanrell, R., et al. (2022). Brain-derived neurotrophic factor-mimetic compounds in biodegradable microspheres as novel neuroprotective approaches for retinal diseases. In Acta Ophthalmologica Vol. 100. Wiley. doi:10.1111/j.1755-3768.2022.0369

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Pendino, M., Garcia Mulero, S., Sanz Pamplona, R., Marcone, S., O'Connell, F., O'Sullivan, J., et al. (2023). Evaluating cannabinoid receptors as a therapeutic target for uveal melanoma. In BRITISH JOURNAL OF PHARMACOLOGY Vol. 180 (pp. 492-493).

 
Professor Patricia Maguire

Kelliher, S., Ní Áinle, F., Weiss, L., Gamba, S., Fouhy, E., Marchetti, M., et al. (2022). Analysis of the Platelet Proteome Reveals Insights into the Pro-Inflammatory and Pro-Thrombotic State Associated with the Philadelphia Chromosome-Negative Myeloproliferative Neoplasms. In Blood Vol. 140 (pp. 2654-2655). American Society of Hematology. doi:10.1182/blood-2022-167119

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Assoc Professor Siobhán McClean

Duggan, N., O’Donoghue, É., Drabinksa, J., Schaffer, K., & McClean, S. (2023). P234 Investigating the role of hypoxia in driving the adaptation of Mycobacterium abscessus infection in cystic fibrosis. In Journal of Cystic Fibrosis Vol. 22 (pp. S137). Elsevier BV. doi:10.1016/s1569-1993(23)00606-9

Available Online
 

Drabinska, J., Mazhova, A., Duggan, N., & McClean, S. (2023). WS07.03 A long-term study of Pseudomonas aeruginosa early patient isolate adaptation to the hypoxic environment. In Journal of Cystic Fibrosis Vol. 22 (pp. S14-S15). Elsevier BV. doi:10.1016/s1569-1993(23)00225-4

Available Online
 

Carey, C., Drabinsak, J., & McClean, S. (2023). The effect of hypoxic conditions on Burkholderia cenocepacia clinical isolates from individuals with cystic fibrosis. In European Cystic Fibrosis Society Conference Vol. Journal of Cystic Fibrosis 22 (2023): S139-S140..

 
Assoc Professor Tadhg Ó'Cróinín

Whelan, M., Simpson, J., & Ó'Cróinín, T. (2023). A DNA Supercoiling - induced secretory phenotype enhances tight junction disruption, adherens junction breakdown and actin remodelling in 3D intestinal Spheroids for Campylobacter jejuni. In Annual Conference Microbiology Society 2023.

 

Carney, G., Clyne, M., & Ó'Cróinín, T. (2023). Aerobic acclimation and acquisition of fluoroquinolone resistance have a similar impact on the phenotype of Campylobacter isolates. In Microbiology Society Annual Conference 2023.

 

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Edited Book

Dr Hilary Cassidy

Iban˜ez Gaspar, V., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). Environmental Contaminants and Endocrine Health (1st edition ed.). O. Carnevali, & G. Hardiman (Eds.), London, United Kingdom: Elsevier Science Publishing Co Inc.

 
Assoc Professor Tara McMorrow

Iban˜ez Gaspar, V., Cassidy, H., Slattery, C., Connolly, L., & McMorrow, T. (2023). Environmental Contaminants and Endocrine Health (1st edition ed.). O. Carnevali, & G. Hardiman (Eds.), London, United Kingdom: Elsevier Science Publishing Co Inc.

 

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Journal article

Professor Oliver Blacque

Chrystal, P. W., Lambacher, N. J., Doucette, L. P., Bellingham, J., Schiff, E. R., Noel, N. C. L., et al. (2022). The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision. Nature Communications, 13(1). doi:10.1038/s41467-022-33820-w

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Dr Gary Brennan

Leavy, A., Brennan, G. P., & Jimenez-Mateos, E. M. (2022). MicroRNA Profiling Shows a Time-Dependent Regulation within the First 2 Months Post-Birth and after Mild Neonatal Hypoxia in the Hippocampus from Mice. Biomedicines, 10(11). doi:10.3390/biomedicines10112740

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Engel, T., Brennan, G. P., & Soreq, H. (2022). Editorial: The molecular mechanisms of epilepsy and potential therapeutics. Frontiers in Molecular Neuroscience, 15. doi:10.3389/fnmol.2022.1064121

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Brindley, E., Heiland, M., Mooney, C., Diviney, M., Mamad, O., Hill, T. D. M., et al. (2023). Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy. Frontiers in Molecular Neuroscience, 16. doi:10.3389/fnmol.2023.1230942

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Dr Kieran Brennan

Kulka, M., Brennan, K., & Gee, M. M. (2022). Investigation of canine extracellular vesicles in diffuse large B-cell lymphomas. PLoS ONE, 17(9 September). doi:10.1371/journal.pone.0274261

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Brennan, K., Iversen, K. F., Blanco-Fernández, A., Lund, T., Plesner, T., & Mc Gee, M. M. (2022). Extracellular Vesicles Isolated from Plasma of Multiple Myeloma Patients Treated with Daratumumab Express CD38, PD-L1, and the Complement Inhibitory Proteins CD55 and CD59. Cells, 11(21). doi:10.3390/cells11213365

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Gorry, R., Brennan, K., Lavin, P. T. M., Sheridan, R., & Mc Gee, M. M. (2023). Phosphorylation of the prolyl isomerase Cyclophilin A regulates its localisation and release from the centrosome during mitosis. Cell Cycle, 22(8), 951-966. doi:10.1080/15384101.2023.2167430

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Gorry, R. L., Brennan, K., Lavin, P. T. M., Mazurski, T., Mary, C., Matallanas, D., et al. (2023). Cyclophilin A Isomerisation of Septin 2 Mediates Abscission during Cytokinesis. International Journal of Molecular Sciences, 24(13). doi:10.3390/ijms241311084

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Professor Geraldine Butler

Bergin, S. A., Zhao, F., Ryan, A. P., Müller, C. A., Nieduszynski, C. A., Zhai, B., et al. (2022). Systematic Analysis of Copy Number Variations in the Pathogenic Yeast Candida parapsilosis Identifies a Gene Amplification in RTA3 That is Associated with Drug Resistance. mBio, 13(5). doi:10.1128/mbio.01777-22

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Igharo, B., Byrne, K. P., Ghnewa, H., Davey, R. P., Fubara, A., Welc, J., et al. (2022). Draft Genome Sequence of the Yeast Torulaspora quercuum Strain UCD657, Isolated from Soil in Ireland. Microbiology Resource Announcements, 11(11). doi:10.1128/mra.00952-22

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Don, A., Byrne, K. P., Alqaderi, F., Mazhova, A., Chaney, B. O. L., Redmond, S., et al. (2022). Draft Genome Sequence of the Yeast Blastobotrys aristata Strain UCD613, Isolated from Soil in Ireland. Microbiology Resource Announcements, 11(11). doi:10.1128/mra.00957-22

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Lombardi, L., Bergin, S. A., Ryan, A., Zuniga-Soto, E., & Butler, G. (2022). CRISPR-Cas9 Editing Induces Loss of Heterozygosity in the Pathogenic Yeast Candida parapsilosis. mSphere, 7(6). doi:10.1128/msphere.00393-22

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Branco, J., Ryan, A. P., Pinto e Silva, A., Butler, G., Miranda, I. M., & Rodrigues, A. G. (2022). Clinical azole cross-resistance in Candida parapsilosis is related to a novel MRR1 gain-of-function mutation. Clinical Microbiology and Infection, 28(12), 1655.e5-1655.e8. doi:10.1016/j.cmi.2022.08.014

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Nourrisson, C., Moniot, M., Lavergne, R. A., Robert, E., Bonnin, V., Hagen, F., et al. (2023). Acquired fluconazole resistance and genetic clustering in Diutina (Candida) catenulata from clinical samples. Clinical Microbiology and Infection, 29(2), 257.e7-257.e11. doi:10.1016/j.cmi.2022.09.021

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Barsh, G. S., Butler, G., Copenhaver, G. P., Crosson, S., Søgaard-Andersen, L., & Stukenbrock, E. H. (2023). Endless microbes most beautiful and most wonderful. PLoS Genetics, 19(4). doi:10.1371/journal.pgen.1010695

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Daneshnia, F., Hilmioglu-Polat, S., Ilkit, M., Fuentes, D., Lombardi, L., Binder, U., et al. (2023). Whole-genome sequencing confirms a persistent candidaemia clonal outbreak due to multidrug-resistant Candida parapsilosis. Journal of Antimicrobial Chemotherapy, 78(6), 1488-1494. doi:10.1093/jac/dkad112

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Daneshnia, F., Arastehfar, A., Lombardi, L., Binder, U., Scheler, J., Vahedi Shahandashti, R., et al. (2023). Candida parapsilosis isolates carrying mutations outside FKS1 hotspot regions confer high echinocandin tolerance and facilitate the development of echinocandin resistance. International Journal of Antimicrobial Agents, 62(1). doi:10.1016/j.ijantimicag.2023.106831

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Professor Annette Therese Byrne

Miller, I. S., Khan, S., Shiels, L. P., Das, S., O' Farrell, A. C., Connor, K., et al. (2022). Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects. Cancer Medicine, 11(20), 3820-3836. doi:10.1002/cam4.4756

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White, K., Connor, K., Meylan, M., Bougoüin, A., Salvucci, M., Bielle, F., et al. (2023). Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy. Annals of Oncology, 34(3), 300-314. doi:10.1016/j.annonc.2022.11.008

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Caulfield, C., Wu, D., Miller, I. S., Byrne, A. T., Mac Aonghusa, P., Zhuk, S., et al. (2023). BF<inf>2</inf>-Azadipyrromethene Fluorophores for Intraoperative Vital Structure Identification. Molecules, 28(5). doi:10.3390/molecules28052167

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Virassamy, B., Caramia, F., Savas, P., Sant, S., Wang, J., Christo, S. N., et al. (2023). Intratumoral CD8<sup>+</sup> T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer. Cancer Cell, 41(3), 585-601.e8. doi:10.1016/j.ccell.2023.01.004

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Biswas, A., Salvucci, M., Connor, K., Düssmann, H., Carberry, S., Fichtner, M., et al. (2023). Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors. Journal of Neuro-Oncology, 163(2), 327-338. doi:10.1007/s11060-023-04341-3

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Li, R., Sant, S., Brown, E., Caramia, F., Nikolic, B., Clarke, K., et al. (2023). Tucatinib promotes immune activation and synergizes with programmed cell death-1 and programmed cell death-ligand 1 inhibition in HER2-positive breast cancer. Journal of the National Cancer Institute, 115(7), 805-814. doi:10.1093/jnci/djad072

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Assoc Professor Gerard Cagney

Zhang, W., Li, J., Silveira, C. P., Cai, Q., Dawson, K. A., Cagney, G., & Yan, Y. (2022). Nanoscale shape-dependent histone modifications.. PNAS nexus, 1(4), pgac172. doi:10.1093/pnasnexus/pgac172

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Davis, J. L., Kennedy, C., Clerkin, S., Treacy, N. J., Dodd, T., Moss, C., et al. (2022). Single-cell multiomics reveals the complexity of TGFß signalling to chromatin in iPSC-derived kidney organoids. Communications biology, 5(1), 1301. doi:10.1038/s42003-022-04264-1

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Susai, S. R., Healy, C., Mongan, D., Heurich, M., Byrne, J. F., Cannon, M., et al. (2022). Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis. Translational Psychiatry, 12(1). doi:10.1038/s41398-022-02217-0

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Dr Hilary Cassidy

Liu, Z., Krstic, A., Neve, A., Casalou, C., Rauch, N., Wynne, K., et al. (2023). Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells. International Journal of Molecular Sciences, 24(14). doi:10.3390/ijms241411821

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Ms Patrizia Colucci

Gómez Sánchez, A., Colucci, P., Moran, A., Moya López, A., Colligris, B., Álvarez, Y., & Kennedy, B. (2023). Systemic treatment with cigarette smoke extract affects zebrafish visual behaviour, intraocular vasculature morphology and outer segment phagocytosis. doi:10.12688/openreseurope.15491.1

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Colucci, P., Giannaccini, M., Baggiani, M., Kennedy, B. N., Dente, L., Raffa, V., & Gabellini, C. (2023). Neuroprotective Nanoparticles Targeting the Retina: A Polymeric Platform for Ocular Drug Delivery Applications. Pharmaceutics, 15(4). doi:10.3390/pharmaceutics15041096

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Dr Eric Conway

Healy, E., McCole, R., Monger, C., Nolan, J., Conway, E., Brien, G., et al. (2022). EZH1-PRC2 Identifies a Potential Reservoir for Disease Relapse in Quiescent Cancer Cells Refractory to EZH2 Enzymatic Inhibition. Blood, 140(Supplement 1), 3049-3050. doi:10.1182/blood-2022-168762

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Assoc Professor John Crean

McKiernan, E. P., Moloney, C., Chaudhuri, T. R., Clerkin, S., Behan, K., Straubinger, R. M., et al. (2022). Formation of hydrated PEG layers on magnetic iron oxide nanoflowers shows internal magnetisation dynamics and generates high in-vivo efficacy for MRI and magnetic hyperthermia. Acta Biomaterialia, 152, 393-405. doi:10.1016/j.actbio.2022.08.033

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Davis, J. L., Kennedy, C., Clerkin, S., Treacy, N. J., Dodd, T., Moss, C., et al. (2022). Single-cell multiomics reveals the complexity of TGFß signalling to chromatin in iPSC-derived kidney organoids. Communications biology, 5(1), 1301. doi:10.1038/s42003-022-04264-1

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Treacy, N. J., Clerkin, S., Davis, J. L., Kennedy, C., Miller, A. F., Saiani, A., et al. (2023). Growth and differentiation of human induced pluripotent stem cell (hiPSC)-derived kidney organoids using fully synthetic peptide hydrogels.. Bioactive materials, 21, 142-156. doi:10.1016/j.bioactmat.2022.08.003

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Dr Jessica Davis

Davis, J. L., Kennedy, C., Clerkin, S., Treacy, N. J., Dodd, T., Moss, C., et al. (2022). Single-cell multiomics reveals the complexity of TGFß signalling to chromatin in iPSC-derived kidney organoids. Communications biology, 5(1), 1301. doi:10.1038/s42003-022-04264-1

Available Online
 

Treacy, N. J., Clerkin, S., Davis, J. L., Kennedy, C., Miller, A. F., Saiani, A., et al. (2023). Growth and differentiation of human induced pluripotent stem cell (hiPSC)-derived kidney organoids using fully synthetic peptide hydrogels.. Bioactive materials, 21, 142-156. doi:10.1016/j.bioactmat.2022.08.003

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Dr Monica De Gaetano

de Gaetano, M. (2023). Development of synthetic lipoxin-A4 mimetics (sLXms): New avenues in the treatment of cardio-metabolic diseases. Seminars in Immunology, 65. doi:10.1016/j.smim.2022.101699

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Millar, B., & de Gaetano, M. (2023). Posing the rationale for synthetic lipoxin mimetics as an adjuvant treatment to gold standard atherosclerosis therapies. Frontiers in Pharmacology, 14. doi:10.3389/fphar.2023.1125858

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Dr Joanna Drabinska

O'Connor, A., Jurado-Martín, I., Mysior, M. M., Manzira, A. L., Drabinska, J., Simpson, J. C., et al. (2023). A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis. MicrobiologyOpen, 12(1). doi:10.1002/mbo3.1311

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Professor William Gallagher

Mazo, C., Aura, C., Rahman, A., Gallagher, W. M., & Mooney, C. (2022). Application of Artificial Intelligence Techniques to Predict Risk of Recurrence of Breast Cancer: A Systematic Review. Journal of Personalized Medicine, 12(9). doi:10.3390/jpm12091496

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Krzyzanowska, A., Barron, S., Loughman, T., Higgins, D. F., Sheehan, K. M., Chan-Ju Wang, A., et al. (2022). 1411P Development and validation of a novel six-gene signature to accurately risk stratify men with early-stage prostate cancer to aid in treatment decision making. Annals of Oncology, 33, S1190. doi:10.1016/j.annonc.2022.07.1897

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Antoranz, A., Van Herck, Y., Bolognesi, M. M., Lynch, S. M., Rahman, A., Gallagher, W. M., et al. (2022). Mapping the Immune Landscape in Metastatic Melanoma Reveals Localized Cell–Cell Interactions That Predict Immunotherapy Response. Cancer Research, 82(18), 3275-3290. doi:10.1158/0008-5472.CAN-22-0363

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Miller, I. S., Khan, S., Shiels, L. P., Das, S., O' Farrell, A. C., Connor, K., et al. (2022). Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects. Cancer Medicine, 11(20), 3820-3836. doi:10.1002/cam4.4756

Available Online
 

Azam, H., Maher, S., Clarke, S., Carruthers, N., Marcone, S., Gallagher, W., & Prencipe, M. (2022). Serum response factor and androgen receptor; partners in crime in prostate cancer progression. European Urology Open Science, 44, S216. doi:10.1016/s2666-1683(22)01976-0

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Connor, K., Conroy, E., White, K., Shiels, L., Keek, S., Ibrahim, A., et al. (2022). MODL-24. ESTABLISHING A CLINICALLY RELEVANT CT AND ASSOCIATED RADIOMICS PIPELINE FOR INTRACRANIAL RODENT TUMOUR MODELS. Neuro-Oncology, 24(Supplement_7), vii295-vii296. doi:10.1093/neuonc/noac209.1151

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Wahlin, S., Boman, K., Moran, B., Nodin, B., Gallagher, W. M., Karnevi, E., & Jirström, K. (2022). Pre-clinical and clinical studies on the role of RBM3 in muscle-invasive bladder cancer: longitudinal expression, transcriptome-level effects and modulation of chemosensitivity. BMC Cancer, 22(1). doi:10.1186/s12885-021-09168-7

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Krzyzanowska, A., Barron, S., Higgins, D. F., Loughman, T., O'Neill, A., Sheehan, K. M., et al. (2023). Development, Validation, and Clinical Utility of a Six-gene Signature to Predict Aggressive Prostate Cancer. European Urology Focus. doi:10.1016/j.euf.2023.04.004

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Azam, H., Maher, S., Clarke, S., Gallagher, W. M., & Prencipe, M. (2023). SRF inhibitors reduce prostate cancer cell proliferation through cell cycle arrest in an isogenic model of castrate-resistant prostate cancer. Cell Cycle, 22(14-16), 1759-1776. doi:10.1080/15384101.2023.2229713

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Slater, K., Bosch, R., Smith, K. F., Jahangir, C. A., Garcia-Mulero, S., Rahman, A., et al. (2023). 1,4-dihydroxy quininib modulates the secretome of uveal melanoma tumour explants and a marker of oxidative phosphorylation in a metastatic xenograft model. Frontiers in Medicine, 9. doi:10.3389/fmed.2022.1036322

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Krzyzanowska, A., Barron, S., Higgins, D., Loughman, T., Sheehan, K., Chan-Ju Wang, A., et al. (2023). Development and clinical validation of a novel biopsy-based six-gene signature to accurately risk-stratify men with early-stage prostate cancer to aid treatment decision making.. Journal of Clinical Oncology, 41(6_suppl), 374. doi:10.1200/jco.2023.41.6_suppl.374

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Krzyzanowska, A., Barron, S., Higgins, D. F., Loughman, T., Sheehan, K. M., Chan-Ju Wang, A., et al. (2023). MP17-08 CLINICAL VALIDATION OF A NOVEL SIX-GENE RISK-STRATIFICATION SIGNATURE TO SUPPORT TREATMENT DECISIONS FOR MEN DIAGNOSED WITH PROSTATE CANCER. Journal of Urology, 209(Supplement 4). doi:10.1097/ju.0000000000003237.08

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Kinsella, Z., Blümel, A., Lucas, M., Lindner, A., Gonzalez, C. A., Rahman, A., et al. (2023). Abstract 5787: Modelling the spatial heterogeneity of CD45-positive tumor infiltrating lymphocytes in early-stage, estrogen receptor-positive breast cancer. Cancer Research, 83(7_Supplement), 5787. doi:10.1158/1538-7445.am2023-5787

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Lucas, M. W., Hurley, C., Kinsella, Z., Gonzalez, C., Burke, C., Rahman, A., et al. (2023). 78P Multiplex immunohistochemistry and digital pathology analysis examining the prevalence and prognostic value of tertiary lymphoid structures in early stage hormone positive, HER2-negative breast cancer. ESMO Open, 8(1), 101301. doi:10.1016/j.esmoop.2023.101301

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Lucas, M., Kinsella, Z., Gonzalez, C. A., Hurley, C., O'Grady, A., Fay, J., et al. (2023). The immune microenvironment in hormone positive, HER2 negative breast cancer: A focus on tumour infiltrating lymphocytes, spatial phenotypes and tertiary lymphoid structures.. Journal of Clinical Oncology, 41(16_suppl), 2522. doi:10.1200/jco.2023.41.16_suppl.2522

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Thagaard, J., Broeckx, G., Page, D. B., Jahangir, C. A., Verbandt, S., Kos, Z., et al. (2023). Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: a report of the international immuno-oncology biomarker working group. Journal of Pathology, 260(5), 498-513. doi:10.1002/path.6155

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Page, D. B., Broeckx, G., Jahangir, C. A., Verbandt, S., Gupta, R. R., Thagaard, J., et al. (2023). Spatial analyses of immune cell infiltration in cancer: current methods and future directions. A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer. Journal of Pathology, 260(5), 514-532. doi:10.1002/path.6165

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Ms Harsha Ganesan

Ganesan, H., Nandy, S. K., Banerjee, A., Pathak, S., Zhang, H., & Sun, X. F. (2022). RNA-Interference-Mediated miR-122-Based Gene Regulation in Colon Cancer, a Structural In Silico Analysis. International Journal of Molecular Sciences, 23(23). doi:10.3390/ijms232315257

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Dr Daniel Hawtree

Görgü, L., Hawtree, D., O'Grady, M. J., Muldoon, C., Masterson, B., Meijer, W. G., et al. (2023). The MÉRA Data Extraction toolkit. Meteorological Applications, 30(1). doi:10.1002/met.2111

Available Online
 
Assoc Professor Caroline Herron

Li, Y., Zhang, F., Herron, C. E., Rosales, I., Heredia, A., Buchete, N. -V., & Rodriguez, B. J. (2023). Cannabidiol-Mediated Sequestration of Alzheimer’s Amyloid-&amp;lt;i&amp;gt;ß&amp;lt;/i&amp;gt; Peptides in ADDL Oligomers. American Journal of Molecular Biology, 13(02), 113-126. doi:10.4236/ajmb.2023.132008

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Dr David Hughes

Demircan, K., Chillon, T. S., Bracken, T., Bulgarelli, I., Campi, I., Du Laing, G., et al. (2022). Association of COVID-19 mortality with serum selenium, zinc and copper: Six observational studies across Europe. Frontiers in Immunology, 13. doi:10.3389/fimmu.2022.1022673

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Karavasiloglou, N., Hughes, D. J., Murphy, N., Schomburg, L., Sun, Q., Seher, V., et al. (2023). Prediagnostic serum calcium concentrations and risk of colorectal cancer development in 2 large European prospective cohorts. American Journal of Clinical Nutrition, 117(1), 33-45. doi:10.1016/j.ajcnut.2022.10.004

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Aglago, E. K., Cross, A. J., Riboli, E., Fedirko, V., Hughes, D. J., Fournier, A., et al. (2023). Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study. British Journal of Cancer, 128(8), 1529-1540. doi:10.1038/s41416-023-02164-7

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Daniel, N., Genua, F., Jenab, M., Mayén, A. -L., Chrysovalantou Chatziioannou, A., Keski-Rahkonen, P., & Hughes, D. J. (2023). The role of the gut microbiome in the development of hepatobiliary cancers.. Hepatology (Baltimore, Md.). doi:10.1097/hep.0000000000000406

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Genua, F., Butt, J., Waterboer, T., & Hughes, D. J. (2023). Association of Antibody Responses to Fusobacterium nucleatum and Streptococcus gallolyticus Proteins with Colorectal Adenoma and Colorectal Cancer. Digestive Diseases and Sciences, 68(8), 3300-3311. doi:10.1007/s10620-023-08001-4

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Professor Breandán Kennedy

Moran, A. L., Fehilly, J. D., Floss Jones, D., Collery, R., & Kennedy, B. N. (2022). Regulation of the rhythmic diversity of daily photoreceptor outer segment phagocytosis in vivo. FASEB Journal, 36(10). doi:10.1096/fj.202200990RR

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Smith, A. J., Advani, J., Brock, D. C., Nellissery, J., Gumerson, J., Dong, L., et al. (2022). GATD3A, a mitochondrial deglycase with evolutionary origins from gammaproteobacteria, restricts the formation of advanced glycation end products. BMC Biology, 20(1). doi:10.1186/s12915-022-01267-6

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Gómez Sánchez, A., Colucci, P., Moran, A., Moya López, A., Colligris, B., Álvarez, Y., & Kennedy, B. (2023). Systemic treatment with cigarette smoke extract affects zebrafish visual behaviour, intraocular vasculature morphology and outer segment phagocytosis. doi:10.12688/openreseurope.15491.1

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Sundaramurthi, H., Tonelotto, V., Wynne, K., O'Connell, F., O’Reilly, E., Costa-Garcia, M., et al. (2023). Ergolide mediates anti-cancer effects on metastatic uveal melanoma cells and modulates their cellular and extracellular vesicle proteomes. doi:10.12688/openreseurope.15973.1

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Slater, K., Bosch, R., Smith, K. F., Jahangir, C. A., Garcia-Mulero, S., Rahman, A., et al. (2023). 1,4-dihydroxy quininib modulates the secretome of uveal melanoma tumour explants and a marker of oxidative phosphorylation in a metastatic xenograft model. Frontiers in Medicine, 9. doi:10.3389/fmed.2022.1036322

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Colucci, P., Giannaccini, M., Baggiani, M., Kennedy, B. N., Dente, L., Raffa, V., & Gabellini, C. (2023). Neuroprotective Nanoparticles Targeting the Retina: A Polymeric Platform for Ocular Drug Delivery Applications. Pharmaceutics, 15(4). doi:10.3390/pharmaceutics15041096

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Martin Kenny

Dhami, S. P. S., Patmore, S., Comerford, C., Byrne, C., Cavanagh, B., Castle, J., et al. (2022). Breast cancer cells mediate endothelial cell activation, promoting von Willebrand factor release, tumor adhesion, and transendothelial migration. Journal of Thrombosis and Haemostasis, 20(10), 2350-2365. doi:10.1111/jth.15794

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Dr Mohd Faheem Khan

Khan, M. F., & Murphy, C. D. (2022). Cytochrome P450 5208A3 is a promiscuous xenobiotic biotransforming enzyme in Cunninghamella elegans. Enzyme and Microbial Technology, 161. doi:10.1016/j.enzmictec.2022.110102

Available Online

Dobson, L. S., Zhang, Q., McKay, B. A., Oke, O., Isanbor, C., Khan, M. F., et al. (2023). Aryl (ß,ß',ß"-Trifluoro)-tert-butyl: A Candidate Motif for the Discovery of Bioactives. Organic Letters. doi:10.1021/acs.orglett.3c02236

Available Online

Khan, M. F., & Murphy, C. D. (2023). Fluorotelomer alcohols are efficiently biotransformed by Cunninghamella elegans. Environmental Science and Pollution Research, 30(9), 23613-23623. doi:10.1007/s11356-022-23901-0

Available Online

Khan, M. F., Chowdhary, S., Koksch, B., & Murphy, C. D. (2023). Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds. Environmental Science and Technology, 57(26), 9762-9772. doi:10.1021/acs.est.3c01240

Available Online

Khan, M. F., Paul Guin, J., Thampi, R. K., Sullivan, J. A., & Murphy, C. D. (2023). Enhanced removal of perfluorooctanoic acid with sequential photocatalysis and fungal treatment. Environmental Science and Pollution Research, 30(39), 91478-91486. doi:10.1007/s11356-023-28588-5

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Dr Lisa Lombardi

Lombardi, L., Bergin, S. A., Ryan, A., Zuniga-Soto, E., & Butler, G. (2022). CRISPR-Cas9 Editing Induces Loss of Heterozygosity in the Pathogenic Yeast Candida parapsilosis. mSphere, 7(6). doi:10.1128/msphere.00393-22

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Salzberg, L. I., Martos, A. A. R., Lombardi, L., Jermiin, L. S., Blanco, A., Byrne, K. P., & Wolfe, K. H. (2022). A widespread inversion polymorphism conserved among Saccharomyces species is caused by recurrent homogenization of a sporulation gene family. PLoS Genetics, 18(11). doi:10.1371/journal.pgen.1010525

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Daneshnia, F., Arastehfar, A., Lombardi, L., Binder, U., Scheler, J., Vahedi Shahandashti, R., et al. (2023). Candida parapsilosis isolates carrying mutations outside FKS1 hotspot regions confer high echinocandin tolerance and facilitate the development of echinocandin resistance. International Journal of Antimicrobial Agents, 62(1). doi:10.1016/j.ijantimicag.2023.106831

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Professor Patricia Maguire

Rohlfing, A. K., Kolb, K., Sigle, M., Ziegler, M., Bild, A., Münzer, P., et al. (2022). ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury. Nature Communications, 13(1). doi:10.1038/s41467-022-29341-1

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Contursi, A., Fullone, R., Szklanna-Koszalinska, P., Marcone, S., Lanuti, P., Taus, F., et al. (2023). Tumor-Educated Platelet Extracellular Vesicles: Proteomic Profiling and Crosstalk with Colorectal Cancer Cells. Cancers, 15(2). doi:10.3390/cancers15020350

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O’Reilly, D., Murphy, C. A., Moore, C. M., Ní Áinle, F., Gormley, I. C., Morrell, C. N., et al. (2023). Markers of platelet activation foR identification of late onset sEpsis in infaNTs: PARENT study protocol. Pediatric Research. doi:10.1038/s41390-023-02812-x

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Weiss, L., MacLeod, H., Comer, S. P., Cullivan, S., Szklanna, P. B., Ní Áinle, F., et al. (2023). An optimized protocol to isolate quiescent washed platelets from human whole blood and generate platelet releasate under clinical conditions. STAR Protocols, 4(2). doi:10.1016/j.xpro.2023.102150

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Dr Mario Manresa

Manresa, M. C., Miki, H., Miller, J., Okamoto, K., Dobaczewska, K., Herro, R., et al. (2022). A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis. Journal of Immunology, 209(12), 2341-2351. doi:10.4049/jimmunol.2200326

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Miki, H., Kiosses, W. B., Manresa, M. C., Gupta, R. K., Sethi, G. S., Herro, R., et al. (2023). Lymphotoxin beta receptor signaling directly controls airway smooth muscle deregulation and asthmatic lung dysfunction. Journal of Allergy and Clinical Immunology, 151(4), 976-990.e5. doi:10.1016/j.jaci.2022.11.016

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Miki, H., & Manresa, M. C. (2023). Novel fibroblast phenotypes in homeostasis and chronic inflammation: From functions to potential regulators. Journal of Physiology, 601(12), 2273-2291. doi:10.1113/JP284620

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Assoc Professor Siobhán McClean

Quinn, C., Tomás-Cortázar, J., Ofioritse, O., Cosgrave, J., Purcell, C., McAloon, C., et al. (2023). GlnH, a Novel Antigen That Offers Partial Protection against Verocytotoxigenic Escherichia coli Infection. Vaccines, 11(1). doi:10.3390/vaccines11010175

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O'Connor, A., Jurado-Martín, I., Mysior, M. M., Manzira, A. L., Drabinska, J., Simpson, J. C., et al. (2023). A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis. MicrobiologyOpen, 12(1). doi:10.1002/mbo3.1311

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Dunne, K., Reece, E., McClean, S., Doyle, S., Rogers, T. R., Murphy, P., & Renwick, J. (2023). Aspergillus fumigatus Supernatants Disrupt Bronchial Epithelial Monolayers: Potential Role for Enhanced Invasion in Cystic Fibrosis. Journal of Fungi, 9(4). doi:10.3390/jof9040490

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Roszkowiak, J., McClean, S., Mironczuk, A. M., & Augustyniak, D. (2023). The Direct Anti-Virulence but Not Bactericidal Activity of Human Neutrophil Elastase against Moraxella catarrhalis. International Journal of Molecular Sciences, 24(7). doi:10.3390/ijms24076607

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Karah, N., Mateo-Estrada, V., Castillo-Ramírez, S., Higgins, P. G., Havenga, B., Khan, W., et al. (2023). The <i>Acinetobacter baumannii</i> website (Ab-web): a multidisciplinary knowledge hub, communication platform, and workspace.. FEMS microbes, 4, xtad009. doi:10.1093/femsmc/xtad009

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Assoc Professor Margaret McGee

Kulka, M., Brennan, K., & Gee, M. M. (2022). Investigation of canine extracellular vesicles in diffuse large B-cell lymphomas. PLoS ONE, 17(9 September). doi:10.1371/journal.pone.0274261

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Brennan, K., Iversen, K. F., Blanco-Fernández, A., Lund, T., Plesner, T., & Mc Gee, M. M. (2022). Extracellular Vesicles Isolated from Plasma of Multiple Myeloma Patients Treated with Daratumumab Express CD38, PD-L1, and the Complement Inhibitory Proteins CD55 and CD59. Cells, 11(21). doi:10.3390/cells11213365

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Gorry, R., Brennan, K., Lavin, P. T. M., Sheridan, R., & Mc Gee, M. M. (2023). Phosphorylation of the prolyl isomerase Cyclophilin A regulates its localisation and release from the centrosome during mitosis. Cell Cycle, 22(8), 951-966. doi:10.1080/15384101.2023.2167430

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Gorry, R. L., Brennan, K., Lavin, P. T. M., Mazurski, T., Mary, C., Matallanas, D., et al. (2023). Cyclophilin A Isomerisation of Septin 2 Mediates Abscission during Cytokinesis. International Journal of Molecular Sciences, 24(13). doi:10.3390/ijms241311084

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Assoc Professor Tara McMorrow

Obaidi, I., Blanco Fernández, A., & McMorrow, T. (2022). Curcumin Sensitises Cancerous Kidney Cells to TRAIL Induced Apoptosis via Let-7C Mediated Deregulation of Cell Cycle Proteins and Cellular Metabolism. International Journal of Molecular Sciences, 23(17). doi:10.3390/ijms23179569

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Ibáñez Gaspar, V., & McMorrow, T. (2023). The Curcuminoid EF24 in Combination with TRAIL Reduces Human Renal Cancer Cell Migration by Decreasing MMP-2/MMP-9 Activity through a Reduction in H<inf>2</inf>O<inf>2</inf>. International Journal of Molecular Sciences, 24(2). doi:10.3390/ijms24021043

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Professor Wim Meijer

Reynolds, L. J., Gonzalez, G., Sala-Comorera, L., Martin, N. A., Byrne, A., Fennema, S., et al. (2022). SARS-CoV-2 variant trends in Ireland: Wastewater-based epidemiology and clinical surveillance. Science of the Total Environment, 838. doi:10.1016/j.scitotenv.2022.155828

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Mahon, J. M., Monleon, A. J. C., Gill, L. W., O’Sullivan, J. J., & Meijer, W. G. (2022). Wastewater-based epidemiology (WBE) for SARS-CoV-2 – A review focussing on the significance of the sewer network using a Dublin city catchment case study. Water Science and Technology, 86(6), 1402-1425. doi:10.2166/wst.2022.278

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Steenbeek, R., Emke, E., Vughs, D., Matias, J., Boogaerts, T., Castiglioni, S., et al. (2022). Spatial and temporal assessment of crack cocaine use in 13 European cities through wastewater-based epidemiology. Science of the Total Environment, 847. doi:10.1016/j.scitotenv.2022.157222

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Görgü, L., Hawtree, D., O'Grady, M. J., Muldoon, C., Masterson, B., Meijer, W. G., et al. (2023). The MÉRA Data Extraction toolkit. Meteorological Applications, 30(1). doi:10.1002/met.2111

Available Online

Cogliati, M., Arikan-Akdagli, S., Barac, A., Bostanaru, A. C., Brito, S., Çerikçioglu, N., et al. (2023). Environmental and bioclimatic factors influencing yeasts and molds distribution along European shores. Science of the Total Environment, 859. doi:10.1016/j.scitotenv.2022.160132

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Martin, N. A., Gonzalez, G., Reynolds, L. J., Bennett, C., Campbell, C., Nolan, T. M., et al. (2023). Adeno-Associated Virus 2 and Human Adenovirus F41 in Wastewater during Outbreak of Severe Acute Hepatitis in Children, Ireland. Emerging Infectious Diseases, 29(4), 751-760. doi:10.3201/eid2904.221878

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Nolan, T. M., Reynolds, L. J., Sala-Comorera, L., Martin, N. A., Stephens, J. H., O'Hare, G. M. P., et al. (2023). Land use as a critical determinant of faecal and antimicrobial resistance gene pollution in riverine systems. Science of the Total Environment, 871. doi:10.1016/j.scitotenv.2023.162052

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Gao, G., O’Sullivan, J. J., Corkery, A., Bedri, Z., O’Hare, G. M. P., & Meijer, W. G. (2023). The Use of Transport Time Scales as Indicators of Pollution Persistence in a Macro-Tidal Setting. Journal of Marine Science and Engineering, 11(5), 1073. doi:10.3390/jmse11051073

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Martin, N. A., Sala-Comorera, L., Gao, G., Corkery, A., Reynolds, L. J., Nolan, T. M., et al. (2023). Inclusion of hydrodynamic properties of bathing waters is critical in selecting faecal indicators to assess public health impacts of faecal contamination. Water Research, 242. doi:10.1016/j.watres.2023.120137

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Professor Cormac Murphy

Sweeney, J. B., McDonnell, K., & Murphy, C. D. (2022). Improving the specificity of E. coli acetate/propionate exclusion biosensors via iterative engineering. Enzyme and Microbial Technology, 160. doi:10.1016/j.enzmictec.2022.110091

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Khan, M. F., & Murphy, C. D. (2022). Cytochrome P450 5208A3 is a promiscuous xenobiotic biotransforming enzyme in Cunninghamella elegans. Enzyme and Microbial Technology, 161. doi:10.1016/j.enzmictec.2022.110102

Available Online

Dobson, L. S., Zhang, Q., McKay, B. A., Oke, O., Isanbor, C., Khan, M. F., et al. (2023). Aryl (ß,ß',ß"-Trifluoro)-tert-butyl: A Candidate Motif for the Discovery of Bioactives. Organic Letters. doi:10.1021/acs.orglett.3c02236

Available Online

Bhatt, P., Chen, S., & Murphy, C. (2023). Editorial: Recent advancements in microbe-pesticide interaction: a smart-soil bioremediation approach. Frontiers in Microbiology, 14. doi:10.3389/fmicb.2023.1206179

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Khan, M. F., & Murphy, C. D. (2023). Fluorotelomer alcohols are efficiently biotransformed by Cunninghamella elegans. Environmental Science and Pollution Research, 30(9), 23613-23623. doi:10.1007/s11356-022-23901-0

Available Online

Khan, M. F., Chowdhary, S., Koksch, B., & Murphy, C. D. (2023). Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds. Environmental Science and Technology, 57(26), 9762-9772. doi:10.1021/acs.est.3c01240

Available Online

Khan, M. F., Paul Guin, J., Thampi, R. K., Sullivan, J. A., & Murphy, C. D. (2023). Enhanced removal of perfluorooctanoic acid with sequential photocatalysis and fungal treatment. Environmental Science and Pollution Research, 30(39), 91478-91486. doi:10.1007/s11356-023-28588-5

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Professor Keith Murphy

Holtby, A. R., McGivney, B. A., Browne, J. A., Katz, L. M., Murphy, K. J., & Hill, E. W. (2023). Variation in salivary cortisol responses in yearling Thoroughbred racehorses during their first year of training. PLoS ONE, 18(4 April). doi:10.1371/journal.pone.0284102

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Holtby, A. R., Hall, T. J., McGivney, B. A., Han, H., Murphy, K. J., MacHugh, D. E., et al. (2023). Integrative genomics analysis highlights functionally relevant genes for equine behaviour. Animal Genetics, 54(4), 457-469. doi:10.1111/age.13320

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Dr Tanja Narancic

Liu, S., Narancic, T., Tham, J. L., & O’Connor, K. E. (2023). ß-oxidation–polyhydroxyalkanoates synthesis relationship in Pseudomonas putida KT2440 revisited. Applied Microbiology and Biotechnology, 107(5-6), 1863-1874. doi:10.1007/s00253-023-12413-7

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Dr Seema Nathwani

Wang, S., Malebari, A. M., Greene, T. F., Kandwal, S., Fayne, D., Nathwani, S. M., et al. (2023). Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells.. Pharmaceuticals (Basel, Switzerland), 16(7), 1000. doi:10.3390/ph16071000

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Assoc Professor David O'Connell

Ward, S. E., Guest, T., Byrne, C., Lopes, P., O'Sullivan, J. M., Doherty, D., et al. (2023). Macrophage Galactose Lectin Contributes to the Regulation of FVIII (Factor VIII) Clearance in Mice - Brief Report. Arteriosclerosis, Thrombosis, and Vascular Biology, 43(4), 540-546. doi:10.1161/ATVBAHA.122.317807

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Professor John O'Connor

Moreton, N., Puzio, M., & O'Connor, J. J. (2022). The effects of the superoxide dismutase mimetic, MnTMPyP, post hypoxia and oxygen glucose deprivation in isolated rat hippocampal slices. Brain Research Bulletin, 190, 105-115. doi:10.1016/j.brainresbull.2022.09.021

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Puzio, M., Moreton, N., Sullivan, M., Scaife, C., Glennon, J. C., & O’Connor, J. J. (2023). An Electrophysiological and Proteomic Analysis of the Effects of the Superoxide Dismutase Mimetic, MnTMPyP, on Synaptic Signalling Post-Ischemia in Isolated Rat Hippocampal Slices. Antioxidants, 12(4). doi:10.3390/antiox12040792

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Professor Kevin O'Connor

Offei, B., Braun-Galleani, S., Venkatesh, A., Casey, W. T., O'Connor, K. E., Byrne, K. P., & Wolfe, K. H. (2022). Identification of genetic variants of the industrial yeast Komagataella phaffii (Pichia pastoris) that contribute to increased yields of secreted heterologous proteins. PLoS Biology, 20(12). doi:10.1371/journal.pbio.3001877

Available Online

Liu, S., Narancic, T., Tham, J. L., & O’Connor, K. E. (2023). ß-oxidation–polyhydroxyalkanoates synthesis relationship in Pseudomonas putida KT2440 revisited. Applied Microbiology and Biotechnology, 107(5-6), 1863-1874. doi:10.1007/s00253-023-12413-7

Available Online

Gaffey, J., O’Donovan, C., Murphy, D., O’Connor, T., Walsh, D., Vergara, L. A., et al. (2023). Synergetic Benefits for a Pig Farm and Local Bioeconomy Development from Extended Green Biorefinery Value Chains. Sustainability (Switzerland), 15(11). doi:10.3390/su15118692

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Assoc Professor Tadhg Ó'Cróinín

Carney, G., Weimer, B. C., Clyne, M., & Cróinín, T. (2023). Different stages of the infection cycle are enriched for Campylobacter strains with distinct phenotypes and levels of fluoroquinolone resistance. Microbiology (United Kingdom), 169(6). doi:10.1099/mic.0.001349

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Assoc Professor Niamh O'Sullivan

Byrne, D. J., Garcia-Pardo, M. E., Cole, N. B., Batnasan, B., Heneghan, S., Sohail, A., et al. (2022). Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia. Acta Neuropathologica Communications, 10(1). doi:10.1186/s40478-022-01343-6

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O'Sullivan, N. (2023). The nilpotent genus of finitely generated residually nilpotent groups. Journal of Group Theory. doi:10.1515/jgth-2022-0098

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Dr Maria Prencipe

Azam, H., Maher, S., Clarke, S., Carruthers, N., Marcone, S., Gallagher, W., & Prencipe, M. (2022). Serum response factor and androgen receptor; partners in crime in prostate cancer progression. European Urology Open Science, 44, S216. doi:10.1016/s2666-1683(22)01976-0

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Azam, H., Maher, S., Clarke, S., Gallagher, W. M., & Prencipe, M. (2023). SRF inhibitors reduce prostate cancer cell proliferation through cell cycle arrest in an isogenic model of castrate-resistant prostate cancer. Cell Cycle, 22(14-16), 1759-1776. doi:10.1080/15384101.2023.2229713

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Dr Jens Rauch

Liu, Z., Krstic, A., Neve, A., Casalou, C., Rauch, N., Wynne, K., et al. (2023). Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells. International Journal of Molecular Sciences, 24(14). doi:10.3390/ijms241411821

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Imoto, H., Rauch, N., Neve, A. J., Khorsand, F., Kreileder, M., Alexopoulos, L. G., et al. (2023). A Combination of Conformation-Specific RAF Inhibitors Overcome Drug Resistance Brought about by RAF Overexpression. Biomolecules, 13(8). doi:10.3390/biom13081212

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Dr Emmanuel Reynaud

Reynaud, E. (2022). The Blaschka legacy, illuminating the oceans from the heart of Europe. FMR magazine (Franco Maria Ricci Magazine).


Dr Julen Tomás Cortázar

Trentelman, J. J. A., de Vogel, F. A., Colstrup, E., Sima, R., Coumou, J., Koetsveld, J., et al. (2022). Identification of novel conserved Ixodes vaccine candidates; a promising role for non-secreted salivary gland proteins. Vaccine, 40(52), 7593-7603. doi:10.1016/j.vaccine.2022.10.032

Available Online

Quinn, C., Tomás-Cortázar, J., Ofioritse, O., Cosgrave, J., Purcell, C., McAloon, C., et al. (2023). GlnH, a Novel Antigen That Offers Partial Protection against Verocytotoxigenic Escherichia coli Infection. Vaccines, 11(1). doi:10.3390/vaccines11010175

Available Online

Rana, V. S., Kitsou, C., Dutta, S., Ronzetti, M. H., Zhang, M., Bernard, Q., et al. (2023). Dome1-JAK-STAT signaling between parasite and host integrates vector immunity and development.. Science (New York, N.Y.), 379(6628), eabl3837. doi:10.1126/science.abl3837

Available Online
Dr Luisa Weiss

Weiss, L., MacLeod, H., Comer, S. P., Cullivan, S., Szklanna, P. B., Ní Áinle, F., et al. (2023). An optimized protocol to isolate quiescent washed platelets from human whole blood and generate platelet releasate under clinical conditions. STAR Protocols, 4(2). doi:10.1016/j.xpro.2023.102150

Available Online
Assoc Professor Margaret Worrall

Singh, S., O’Reilly, S., Gewaid, H., Bowie, A. G., Gautier, V., & Worrall, D. M. (2022). Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication. International Journal of Molecular Sciences, 23(20). doi:10.3390/ijms232012522

Available Online
Dr Yan Yan

Zhang, W., Li, J., Silveira, C. P., Cai, Q., Dawson, K. A., Cagney, G., & Yan, Y. (2022). Nanoscale shape-dependent histone modifications.. PNAS nexus, 1(4), pgac172. doi:10.1093/pnasnexus/pgac172

Available Online

Wang, Y. F., Zhou, Y., Sun, J. B., Wang, X., Jia, Y., Ge, K., et al. (2023). The Yin and Yang of the protein corona on the delivery journey of nanoparticles. Nano Research, 16(1), 715-734. doi:10.1007/s12274-022-4849-6

Available Online

Behan, J. A., Xie, Z., Wang, Y. F., Yang, X., Aastrup, T., Yan, Y., et al. (2023). Quartz Crystal Microbalance Method to Measure Nanoparticle-Receptor Interactions and Evaluate Nanoparticle Design Efficiency. JACS Au, 3(6), 1623-1633. doi:10.1021/jacsau.3c00084

Available Online

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Other

Dr Daniel Hawtree

Zurovec, O., Hawtree, D., Leach, S., & Lynch, B. (2023). Impact of agricultural land use and management on available soil phosphorus content in agricultural catchments of Ireland. doi:10.5194/egusphere-egu23-17071

Available Online
 

Mellander, P. -E., Hawtree, D., Ezzati, G., Murphy, C., Galloway, J., Jackson-Blake, L., et al. (2023). Land to water phosphorus transfer processes under climate change. doi:10.5194/egusphere-egu23-6014

Available Online
 

Hawtree, D., Galloway, J., Zurovec, O., Jackson-Blake, L., Norling, M., & Mellander, P. -E. (2023). Performance of a Parsimonious Phosphorus Model (SimplyP) in Two Contrasting Agricultural Catchments in Ireland. doi:10.5194/egusphere-egu23-7759

Available Online
 

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Poster

Dr Jana Haase

Jones, A. K. C., Spreng, S. A., Brown, E., Mc Veigh, C. J., Inoue, A., Ahnert-Hilger, G., & Haase, J. (2023). Serotonin transporter regulation by Ga proteins: evidence for coupling of serotonin transport and the G protein cycle. Poster session presented at the meeting of 20th Meeting of the International Society for Serotonin Research "Serotonin on the Mexican Caribbean”.

 

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Preprint

Professor Oliver Blacque

Pir, M., Yenisert, F., Karaman, A., Begar, E., Tsiropoulou, S., Firat-Karalar, E. N., et al. (2023). CilioGenics: an integrated method and database for predicting novel ciliary genes. doi:10.1101/2023.03.31.535034

Available Online
 
Dr Eric Conway

Deevy, O., Monger, C., Matrà, F., Tuck, E., Conway, E., Rodighiero, S., et al. (2023). Dominant negative and directional dysregulation of Polycomb function in<i>EZH2</i>-mutant human growth disorders. doi:10.1101/2023.06.01.543208

Available Online
 
Dr Emmanuel Reynaud

Andrea, S., Kevin, M., Brian J, R., & Emmanuel G, R. (2023). The Use of Fluid-phase 3D Printing to Pattern Alginate-gelatin Hydrogel Properties to Guide Cell Growth and Behaviour<i>In Vitro</i>. doi:10.1101/2023.07.08.547691

Available Online
 

Reynaud, E., Gutierrez-Heredia, L., Garbett, A., Horn, E., Carlsson, J., & Collins, P. (2023). Rise of the Cybercrabs: how digital cloning in an integrated taxonomic framework can support deep-sea exploration. doi:10.1101/2023.03.16.532964

Available Online
 

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