Newsletter; Publications

WORKING TOWARDS BETTER RHEUMATIC AND ARTHRITIS RESEARCH - TOGETHER

News Rheum is a quarterly newsletter created in response to feedback from patient insight partners at our first Patient Voice in Arthritis Research discussion forum. It is co-produced by patients and researchers with each edition focussing on a specific theme.

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Publications 

Abdalla, A., Khalid, M., Ishaq, Q. et al. Scleroderma-associated cutaneous calcinosis: a remarkable regression post stem cell transplantation. Clin Rheumatol 40, 789–790 (2021). https://doi.org/10.1007/s10067-020-05368-x

Adeeb F, Dorris ER, Morgan NE, Lawless D, Maqsood A, Ng WL, Killeen O, Cummins EP, Taylor CT, Savic S, Wilson AG, Fraser A. A Novel RELA Truncating Mutation in a Familial Behçet’s Disease–like Mucocutaneous Ulcerative Condition, Arthritis and Rheumatology 73(3):490-497. DOI: https://doi.org/10.1002/art.41531

Canavan, M., Floudas, A., Veale, D.J. et al. The PD-1:PD-L1 axis in Inflammatory Arthritis. BMC Rheumatol 5, 1 (2021). https://doi.org/10.1186/s41927-020-00171-2

Carmel Stober, Deepak R. Jadon, April W. Armstrong, Vinod Chandran, Maarten de Wit, Philip S. Helliwell, Philip Mease, Alexis Ogdie, Denis O’Sullivan, Stephen R. Pennington, Thorvardur Löve, Alberto Cauli, Leonieke van Mens, Robin Waxman, Jose U. Scher, Anne Barton, Christopher T. Ritchlin and Oliver FitzGerald. Proceedings of the 2020 GRAPPA Collaborative Research Network (CRN) Meeting, J Rheumatol Suppl. 2021 Jun;97:4-9. https://doi.org/10.3899/jrheum.201667

Cunningham, C. C., Wade, S., Floudas, A., Orr, C., et al. Serum miRNA Signature in Rheumatoid Arthritis and "At-Risk Individuals", Front. Immunol., 03 March 2021. DOI: https://doi.org/10.3389/fimmu.2021.633201

Donnelly S, Wilson AG, Mannan H, Dix C, Whitehill L, Kroll T. (In)Visible illness: A photovoice study of the lived experience of self-managing rheumatoid arthritis. PLoS One. 2021 Mar 8;16(3):e0248151. doi: 10.1371/journal.pone.0248151. Erratum in: PLoS One. 2021 Apr 14;16(4).

Flora Farkas, F., Natsumi Ikumi, N., Elmamoun, M., Agnes Szentpetery, A., FitzGerald, O. Comparison of Composite Measure Remission Targets in Psoriatic Arthritis. The Journal of Rheumatology March 2021, jrheum.200556; DOI: https://doi.org/10.3899/jrheum.200556

Floudas, A., Canavan, M., McGarry, T., Mullan, R., et al. ACPA Status Correlates with Differential Immune Profile in Patients with Rheumatoid Arthritis, Cells 2021, 10(3), 647. DOI: https://doi.org/10.3390/cells10030647

From intent to implementation: Factors affecting public involvement in life science research, PLOS ONE. 2021 Apr 28;16(4): e0250023. doi: 10.1371/journal.pone.0250023. eCollection 2021. John A Burns, Sinead Holden, Kora Korzec, Emma R Dorris

Goodchild, C., O’Rourke, M., Haroon, M. et al. 5-year longitudinal study of clinical and patient-reported outcomes in acute anterior uveitis. Eye 35, 651–658 (2021). https://doi.org/10.1038/s41433-020-0937-6

Helliwell, P.S., Tillett, W., Waxman, R., Coates, L.C., Brooke, M., FitzGerald, O., Packham, J. C., and McHugh, N., on behalf of the PROMPT Study Group Evaluation and Validation of a Patient-completed Psoriatic Arthritis Flare Questionnaire. The Journal of Rheumatology February 2021, jrheum.201317; DOI: https://doi.org/10.3899/jrheum.201317

Is chronic non-infectious osteomyelitis with mandibular involvement a distinct disease?

Jagpal, A., Rahn, E.J., Mudano, A.S., Dalbeth, N., Taylor, W., et al. Which factors predict discordance between a patient and physician on a gout flare?, Rheumatology, Volume 60, Issue 2, February 2021, Pages 773–779, https://pubmed.ncbi.nlm.nih.gov/32793971/

Kieran Murray, Sean Quinn, Matthew Turk, Anna O’Rourke, Eamonn Molloy, Lorraine O’Neill, Ann Barbara Mongey, Ursula Fearon, Douglas J Veale, COVID-19 and rheumatic musculoskeletal disease patients: infection rates, attitudes and medication adherence in an Irish population, Rheumatology, Volume 60, Issue 2, February 2021, Pages 902–906, https://doi.org/10.1093/rheumatology/keaa694

Kieran Orr, C., Vieira-Sousa, E., Fonseca, J. E., Veale, D., Arthroscopic Guided Synovial Biopsies, Front Med (Lausanne). 2021 Feb 11(7) https://doi.org/10.3389/fmed.2020.604582

Leung, Y.Y., Orbai, A.M., Tillett, W., Ogdie, A., Eder, L., et al. Instruments Measuring Physical Function for Psoriatic Arthritis Endorsed at GRAPPA 2020 Annual Meeting: Updates of the GRAPPA-OMERACT Working Group. The Journal of Rheumatology March 2021, DOI: https://doi.org/10.3899/jrheum.201679

McGarry T, Hanlon MM, Marzaioli V, Cunningham CC, Krishna V, Murray K, Hurson C, Gallagher P, Nagpal S, Veale DJ, Fearon U. Rheumatoid arthritis CD14+ monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease. Clin Transl Immunology. 2021 Jan 19;10(1):e1237. doi: 10.1002/cti2.1237. PMID: 33510894; PMCID: PMC7815439.

Modifications in a UK Multicenter Study. The Journal of Rheumatology March 2021. DOI: https://doi.org/10.3899/jrheum.201674

Murray K, Floudas A, Murray C, et al. First use of tofacitinib to treat an immune checkpoint inhibitor-induced arthritis BMJ Case Reports CP 2021;14. https://casereports.bmj.com/content/14/2/e238851

Murray, Grainne M et al. The Lancet Rheumatology, Volume 3, Issue 2, e90 - e92. DOI: https://doi.org/10.1016/S2665-9913(20)30414-8

Murray, K., Turk, M., Alammari, Y. et al. Long-term remission and biologic persistence rates: 12-year real-world data. Arthritis Res Ther 23, 25 (2021). https://doi.org/10.1186/s13075-020-02380-z

Nair N, Barton A, Wilson AG. Cell-specific epigenetic drivers of pathogenesis in rheumatoid arthritis. Epigenomics. 2021 Apr;13(7):549-560. doi: 10.2217/epi-2020-0380. Epub 2021 Apr 6. PMID: 33820439.

O’Leary, D., Killeen, O.G. & Wilson, A.G. Genetics of chronic nonbacterial osteomyelitis in the irish population: no significant association with rare FBLIM1 variants. Pediatr Rheumatol 19, 32 (2021). https://doi.org/10.1186/s12969-021-00533-1

O’Leary, D., Wilson, A.G., MacDermott, EJ. et al. Variability in phenotype and response to treatment in chronic nonbacterial osteomyelitis; the Irish experience of a national cohort. Pediatric Rheumatology 19, 45 (2021). DOI: https://doi.org/10.1186/s12969-021-00530-4

Oliver J, Nair N, Orozco G, Smith S, Hyrich KL, Morgan A, Isaacs J, Wilson AG; BRAGGSS, Barton A, Plant D. Transcriptome-wide study of TNF-inhibitor therapy in rheumatoid arthritis reveals early signature of successful treatment. Arthritis Res Ther. 2021 Mar 10;23(1):80. doi: 10.1186/s13075-021-02451-9. Erratum in: Arthritis Res Ther. 2021 May 8;23(1):139. PMID: 33691749; PMCID: PMC7948368. 

Oliver, J., Nair, N., Orozco, G. et al. Correction to: Transcriptome-wide study of TNF-inhibitor therapy in rheumatoid arthritis reveals early signature of successful treatment. Arthritis Res Ther 23, 139 (2021). https://doi.org/10.1186/s13075-021-02519-6

Stober C, Jadon DR, Armstrong AW, Chandran V, de Wit M, Helliwell PS, Mease P, Ogdie A, O'Sullivan D, Pennington SR, Löve T, Cauli A, van Mens L, Waxman R, Scher JU, Barton A, Ritchlin CT, FitzGerald O. (2021). Proceedings of the 2020 GRAPPA Collaborative Research Network (CRN) Meeting. The Journal of Rheumatology, February 2021 jrheum.201667.

Taylor, W., Dalbeth, N., Saag, K.G., Singh, J.A., Rahn, et al. Flare Rate Thresholds for Patient Assessment of Disease Activity States in Gout. The Journal of RheumatologyFeb 2021, 48 (2) 293-298;https://doi.org/10.3899/jrheum.191242

Tedeschi, S.K., Pascart, T., Latourte, A., Godsave, C., Kundakci, B., Naden, R.P., Taylor, W.J., Dalbeth, N., Neogi, T., Perez-Ruiz, F., Rosenthal, A., Becce, F., Pascual, E., Andres, M., Bardin, T., Doherty, M., Ea, H.-K., Filippou, G., FitzGerald, J., Guitierrez, M., Iagnocco, A., Jansen, T.L., Kohler, M.J., Lioté, F., Matza, M., McCarthy, G.M., Ramonda, R., Reginato, A.M., Richette, P., Singh, J.A., Sivera, F., So, A., Stamp, L.K., Yinh, J., Yokose, C., Terkeltaub, R., Choi, H. and Abhishek, A. (2021), Identifying potential classification criteria for calcium pyrophosphate deposition disease (CPPD): Item generation and item reduction. Arthritis Care & Research. Accepted Author Manuscript. https://doi.org/10.1002/acr.24619 

Tillett, W., FitzGerald, O., Coates, L.C., Packham, J., Deepak, J. R., et al. on behalf of the PROMPT Study Group. Composite Measures for Routine Clinical Practice in Psoriatic Arthritis: Testing of Shortened Versions in a UK Multicenter Study. The Journal of Rheumatology March 2021, jrheum.201675; DOI: https://doi.org/10.3899/jrheum.201675

Tillett, W., FitzGerald, O., Coates, L.C., Packham, J., Deepak, J. R., et al. on behalf of the PROMPT Study Group. Composite Measures for Clinical Trials in Psoriatic Arthritis: Testing Pain and Fatigue

Turk M, Murray K, Alammari Y, et alThe effects of alcohol consumption and its associations with disease activity among 979 patients with inflammatory arthritisRMD Open 2021;7:e001510. doi: 10.1136/rmdopen-2020-001510

Turk, J.N., Zahavi, E.R., Gorman, A.E. et al. Exploring the effect of alcohol on disease activity and outcomes in rheumatoid arthritis through systematic review and meta-analysis. Sci Rep 11, 10474 (2021). https://doi.org/10.1038/s41598-021-89618-1