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Develop novel molecular processes and techniques for use in biotechnology

A key aim of this research theme is to develop and enhance world-leading molecular research techniques that can then be utilised in the biotechnology and biomedical industry. This includes investigating novel crop varieties to tackle the ever-increasing threat of disease, and developing targeted CRISPR technology that will assist alleviating challenges produced by climate change. The theme also encompasses the development of novel in vitro mammalian cell models and tests for disease detection.


Paul McCabe: GRASS: Green Research Applications For Market Success. (Enterprise Ireland Innovation Partnership Grant) 2018-2020

Paul McCabe: One plant – dozens of applications: Establishing a breeding programme for the highly versatile crop Cannabis sativa. (IRC Enterprise Partnership Postdoctoral Scheme) 2019-2021

Paul McCabe / Joanna Kacprzyk: Pharming of high value compounds from plant cell cultures grown in bioreactors. (UCD Newman Postdoctoral Fellowship) 2019-2021

Rainer Melzer: The development of wheat varieties with enhanced disease resistance and gene containment. (UCD-CSC Scholarship) 2017-2021

Rainer Melzer: Towards establishing hemp as a sustainable crop for Irish agriculture. (IRC-EPA postgraduate scholarship) 2019-2023

Rainer Melzer: A developmental and genetic analysis of flower development in hemp - Cannabis sativa (UCD-CSC Scholarship) 2019-2023

Carl Ng: CRISPR on Guard: a novel approach for regulating gene expression in stomatal guard cells for climate smart agriculture. (IRC) 2016-2020

Antoinette Perry: epiCaPture: developing a urine test for early detection of aggressive prostate cancer. (Enterprise Ireland) 2019-2021

Jeremy Simpson: Development of a high-content screening imaging and analysis platform to dissect nanoparticle-cell interactions in 3D cell culture systems. This project provides a national platform to enable quantitative studies of novel classes of nanoparticles, as therapeutic delivery devices, to be tested on in vitro 3D animal cell models. (SFI Curam Research Centre for Medical Devices) 2016-2021

Jeremy Simpson: Molecular dissection of the mechanisms of nanoparticle penetrance into 3D cancer cell models. This project aims to develop several new models of cancer spheroids representing various human tissues and organs, and then investigate the mechanisms by which synthetic nanoparticles enter these spheroids and then transit between individual cells. (IRC) 2019-2023

School of Biology and Environmental Science