SBBS Research Scholarships 2023:
Project title: The serotonin transporter as a G protein-coupled transporter: in vitro and in vivo evidence for coupling of serotonin transport and the G protein cycle
PI: Dr (opens in a new window)Jana Haase
The laboratory of Dr. Jana Haase is seeking to recruit a PhD student to study a novel regulatory mechanism of the serotonin transporter (SERT). Our recent data suggest that SERT interacts with heterotrimeric G proteins in much the same way as G protein coupled receptors (GPCRs). The aim of this project is to study in detail the G protein-SERT interaction and its consequences for SERT function, serotonin signalling, and the mechanism of action of antidepressants and psychostimulants. The results of the project are also expected to generate novel insight into molecular mechanisms underlying disease-associated SERT variants. The project will provide the candidate with state-of-the-art training in the areas of molecular biology, biochemistry, cell biology, pharmacology and non-mammalian animal models (C. elegans) as well as networking opportunities through local and international collaborations.
Requirements:Applicants should have a minimum of upper 2nd class honours
degree in Neuroscience, Pharmacology, Biochemistry, Cell Biology or related biomedical science
discipline.
Conditions:
- September/October 2023 start date.
- Full EU fees + €20,000 per annum stipend over four years; EU/UK applicants only
- The student will be enrolled in a Structured PhD programme, associated with the School.
- Each student is required to demonstrate in appropriate laboratory practicals as part of their funded scholarship. Demonstrating hours and lab practicals are detailed and assigned by the SBBS Demonstrating Committee (maximum hours: 288 per annum) .
- The student and supervisor are required to submit an application for an IRC Postgraduate Scholarship in the first year of their SBBS-funded research scholarship
Apply: Applications should contain a 1-page cover letter outlining your interest and suitability for the
position, a detailed CV and contact information for 2 referees. Applications should be received by
email to jana.haase@ucd.ie, no later than July 30th 2023. Informal inquiries may be made by
email prior to the application deadline.