Drug-induced Renal disease, Diabetic Kidney Disease, Renal cancer, Primary Cilia, Proteomics, Toxicology, Nanotoxicology, Novel Therapeutics
Cancer
Cancer research activity within SBBS is focused on the identification, mechanistic anchoring and clinical validation of molecular determinants of tumour progression, with a particular interest in biomarker discovery/translation and drug development to facilitate precision therapy.
SBBS cancer researchers are centrally involved in flagship nationally-funded cancer research programmes, for example the SFI-funded strategic research cluster (opens in a new window)(opens in a new window)Molecular Therapeutics for Cancer Ireland, and the Irish Cancer Society’s first collaborative cancer research centre,(opens in a new window)(opens in a new window) Breast-Predict.
Research Interests: Chromatin, Histone Modifications, Epigenetics, Transcription, Acute Myeloid Leukemia, Ovarian Cancer
Research Interests: (opens in a new window)BREAST-PREDICT; biomarkers; breast cancer; melanoma; proteomics; tumour progression.
Research Interests: Model organisms, Xenopus; Aven; apoptosis; cell cycle regulation.
Research Interests: NMR spectroscopy; molecular modelling; peptides; Structural biology; diabetes; antimicrobial; protein; GIP structure; GPCR structure.
Research Interests: Cancer Epidemiology, Cohort Studies, Genetics, Dietary/lifestyle, Nutrition, Micronutrients, Metabolism, Microbiome, Gastrointestinal Cancers.
Research Interests: Vision and Blindness; Ocular Pharmacology and Genetics; Colorectal Cancer; Vascular Biology; Neurodegeneration; Drug Discovery and Delivery.
Research Interests: Mechanisms of Disease; Cancer; Blood and bone cancer; Tumour microenvironment, Extracellular vesicles (EVs), EV-based liquid biopsy, Multiomics; Peptidyl prolyl isomerases; Cyclophilin A; Bcl-2 proteins.
Research Interests: biotherapeutics; biotechnology; activity of the calcium binding protein secretagogin in neuronal cells; protein networks.
Research Interests: bioinformatics, including gene expression data analysis; genomics.
Research Interests: serpin (serine protease inhibitor) superfamily of proteins; role of particular serpins in cancer; 'non-inhibitory serpins' including PEDF (pigment epithelial derived factor), maspin (mammary serpin) and thyroxine binding.