Charles Seminar Series 2020-21,'Scarring Alopecias' with guest speaker Matt Harries, Wednesday 12th May at 12Pm
Date of Talk: 12th Mau at 12PM via Adobe Connect
Talk Title: Scarring Alopecias
Speaker Details; Affiliation: Dr Matt Harries, PhD, FRCP,The Dermatology Centre, Salford Royal NHS Foundation Trust, Salford, Greater Manchester, UK; andCentre for Dermatology Research, University of Manchester, MAHSC and NIHR Manchester Biomedical Research Centre, Manchester, UK.
If you are UCD-affiliated or a consultant dermatologist in Ireland and would like to register for this talk, please email firstname.lastname@example.org
Dr Matthew Harries became a Specialist Registrar in Dermatology in Manchester in 2003. During training he spent time studying the hair immune system in cicatricial alopecias, working in both Manchester and Lübeck with Professor Ralf Paus. He was awarded a PhD from the University of Manchester in 2011. He now works as a Consultant Dermatologist in Salford and is an Honorary Senior Lecturer at the University of Manchester. He is the deputy lead for the NIHR Manchester BRC inflammatory hair disorders program, and a committee member for the British Hair and Nails Society, BSF large grant awards committee and Alopecia UK research committee. He is currently leading the BAD guidelines update for alopecia areata and is writing a chapter in the next Rook Textbook of Dermatology.
Abstract for talk
Primary cicatricial alopecias (PCA) are a rare group of inflammatory disorders that cause permanent hair loss. They are characterised clinically by loss of visible follicular ostia with variable degrees of inflammation, and histologically by perifollicular inflammation, hair follicle destruction with eventual replacement of follicles with scar-like fibrous tissue. It is of paramount importance that clinicians who manage patients with hair loss can accurately diagnose these disorders. The aim of this talk is to present a rational and pragmatic guide to the assessment, investigation, diagnosis, and treatment of patients with PCA, focusing on particularly on lichen planopilaris and frontal fibrosing alopecia. Pathogenesis will also be discussed, particularly highlighting hair follicle stem cell loss, immune privilege collapse and EMT as key processes in permanent hair follicle destruction.