Skin biomarker study in Parkinsonian syndromes


Project Title: Skin biomarker study in Parkinsonian syndromes

Thematic Area: Skin-Non Skin Axes

Focus of Research: Parkinson's


This is a collaborative research between DNI and University College Dublin (UCD). Our goal is to look for early and non-invasive diagnostic marker for Parkinson's disease and differentiate it from other parkinsonian disorders such as multisystem atrophy (MSA), progressive supranuclear palsy (PSP), diffuse lewy body disease (DBLD), corticobasal degeneration (CBD) and fronto-temporal dementia (FTD). We will collect skin samples with sebutape and punch biopsy, as well as blood samples will be taken to examine the expression of proteins as well as quantify the proteins associated with the above mentioned diseases to establish skin as a potential biomarker.

Funded by: Michael J. Fox Foundation

PI: Prof. Timothy Lynch

Other Group/team members: Dr Dimitra Khalil-Chaity, Prof Desmond Tobin

Project Duration: January 2020- January 2024